Best TWAS P=2.12e-07 · Best GWAS P=2.23e-07 conditioned to 0.179
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RP9P | 0.02 | 0.02 | lasso | 1 | 0.02 | 2.1e-05 | 5.2 | 5.2 | 2.2e-07 | 1.00 | 0 | 0.99 | FALSE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | KBTBD2 | 0.06 | 0.01 | lasso | 3 | 0.01 | 7.2e-02 | 5.1 | 5.2 | 2.1e-07 | 0.87 | 0 | 0.68 | TRUE |