Best TWAS P=7.72e-09 · Best GWAS P=4.68e-08 conditioned to 0.758
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | RMI1 | 0.07 | 0.06 | lasso | 3 | 0.06 | 1.4e-07 | 5.3 | -5.4 | 6.9e-08 | -0.97 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Testis | RMI1 | 0.12 | 0.11 | enet | 15 | 0.14 | 1.3e-06 | -4.6 | -5.5 | 3.4e-08 | -0.81 | 0.03 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RMI1 | 0.02 | 0.02 | blup | 31 | 0.01 | 8.8e-04 | 5.3 | -5.8 | 7.7e-09 | -0.93 | 0.01 | 0.91 | TRUE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | RMI1 | 0.03 | 0.03 | lasso | 4 | 0.04 | 4.1e-05 | 5.3 | -5.7 | 1.5e-08 | -0.91 | 0.01 | 0.96 | FALSE |
| 5 | The Cancer Genome Atlas | Brain Lower Grade Glioma | RMI1 | 0.03 | 0.03 | blup | 31 | 0.01 | 1.2e-02 | 5.3 | -5.6 | 1.6e-08 | -0.97 | 0.01 | 0.96 | FALSE |