TWAS
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Usage
Models
Genes
Traits
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Traits
:
Reaction Time
:
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chr20:46,840,115-48,410,403
Best TWAS P=8.44e-08 · Best GWAS P=1.43e-06 conditioned to 0.327
46.8M
47M
47.2M
47.4M
47.6M
47.8M
48M
48.2M
48.4M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Colon Transverse
ARFGEF2
0.11
0.07
enet
12
0.09
2.9e-05
-4.4
-5.4
8.4e-08
-0.79
0.04
0.91
TRUE
1
GTEx
Artery Tibial
CSE1L
0.12
0.03
lasso
6
0.04
3.8e-04
-4.6
-5.3
1.5e-07
-0.69
0.04
0.93
FALSE