Best TWAS P=6.5e-09 · Best GWAS P=2.45e-09 conditioned to 0.0143
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | CCDC85A | 0.07 | 0.04 | lasso | 3 | 0.03 | 3.2e-04 | -5.8 | -5.8 | 6.5e-09 | 0.75 | 0.00 | 0.99 | TRUE |
| 2 | GTEx | Brain Cerebellar Hemisphere | CCDC85A | 0.28 | 0.23 | lasso | 4 | 0.19 | 1.2e-05 | 5.2 | 5.2 | 2.0e-07 | -0.49 | 0.07 | 0.80 | FALSE |
| 3 | GTEx | Thyroid | CCDC85A | 0.17 | 0.08 | lasso | 6 | 0.05 | 6.4e-05 | 5.2 | 5.3 | 1.1e-07 | -0.52 | 0.06 | 0.93 | FALSE |