Best TWAS P=2.84e-09 · Best GWAS P=4.18e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | THOC7 | 0.10 | 0.10 | lasso | 5 | 0.06 | 2.7e-08 | 5.9 | -5.9 | 2.8e-09 | -1.00 | 0.00 | 1.00 | TRUE |
| 2 | GTEx | Testis | THOC7 | 0.18 | 0.04 | lasso | 3 | 0.04 | 6.8e-03 | 3.7 | -5.2 | 2.2e-07 | -0.64 | 0.04 | 0.73 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | THOC7 | 0.18 | 0.15 | bslmm | 599 | 0.16 | 2.1e-20 | 5.9 | -5.5 | 4.5e-08 | -0.91 | 0.00 | 1.00 | FALSE |