[Hub]/) : Traits : Systolic Blood Pressure : ← →

chr1:47,997,898-49,629,562

Best TWAS P=6.06e-08 · Best GWAS P=5.09e-09 conditioned to 7.02e-09

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Hippocampus RP5-1024N4.4 0.27 0.07 lasso 9 0.12 1.1e-03 5.1 5.2 2.5e-07 -0.01 0.01 0.95 FALSE
2 GTEx Brain Nucleus accumbens basal ganglia RP5-1024N4.4 0.28 0.26 lasso 8 0.27 5.2e-08 5.1 5.2 2.5e-07 -0.02 0.01 0.99 FALSE
3 GTEx Breast Mammary Tissue (Female) RP5-1024N4.4 0.32 0.18 enet 18 0.21 9.1e-07 5.1 5.3 1.0e-07 -0.03 0.01 0.99 FALSE
4 GTEx Cells Transformed fibroblasts RP5-1024N4.4 0.10 0.08 lasso 4 0.08 1.3e-06 5.2 5.2 1.5e-07 -0.03 0.01 0.99 FALSE
5 GTEx Esophagus Muscularis RP5-1024N4.4 0.35 0.35 lasso 4 0.37 3.1e-23 5.1 5.4 6.1e-08 -0.01 0.01 0.99 TRUE
6 GTEx Heart Atrial Appendage RP5-1024N4.4 0.31 0.23 lasso 7 0.20 2.6e-09 5.0 5.2 1.9e-07 -0.02 0.01 0.99 FALSE
7 GTEx Liver SPATA6 0.20 0.15 enet 20 0.15 5.9e-05 5.2 -5.3 1.2e-07 0.01 0.01 0.96 FALSE
8 GTEx Pituitary RP5-1024N4.4 0.21 0.30 lasso 7 0.29 5.3e-08 5.0 5.1 2.9e-07 -0.02 0.01 0.99 FALSE
9 GTEx Stomach RP5-1024N4.4 0.26 0.26 lasso 6 0.25 2.1e-12 5.1 5.2 2.5e-07 -0.01 0.01 0.99 FALSE
10 GTEx Vagina RP5-1024N4.4 0.31 0.19 lasso 8 0.14 4.9e-04 5.1 5.2 1.7e-07 0.00 0.01 0.95 FALSE
11 The Cancer Genome Atlas Lung Squamous Cell Carcinoma SLC5A9 0.07 0.02 enet 17 0.04 3.4e-05 -4.4 5.3 1.4e-07 -0.02 0.01 0.73 FALSE