Hub : Traits :

Systolic Blood Pressure

5611 significantly associated models · 1282 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 752566 2761863 28 9 1.2e-24 1.0e-23 NaN NaN ANKRD65 LOC441869 NADK PUSL1 SLC35E2
2 1 5611729 7460433 4 1 4.6e-11 3.1e-10 2.1e-02 87 THAP3
3 1 7715776 9571422 2 1 8.0e-14 5.0e-13 1.0e+00 100 RERE
4 1 10435170 12731572 10 9 1.2e-95 4.9e-87 NaN NaN AGTRAP CLCN6 FBXO6 MTHFR NPPA RP4-635E18.7
5 1 15119708 16844848 11 2 4.4e-21 1.2e-15 6.9e-03 89 PLEKHM2 SPEN
6 1 24372971 25768937 1 1 1.1e-08 7.5e-14 7.5e-13 8 CLIC4
7 1 26327671 30246262 12 4 1.2e-13 1.7e-09 4.7e-01 99 FCN3 MECR PHACTR4 PIGV
8 1 35489692 36134052 1 1 2.0e-07 9.6e-08 1.6e-01 93 ZMYM4
9 1 37480144 39186794 6 1 1.2e-12 4.4e-11 8.7e-01 100 FHL3
10 1 40791792 44618031 14 3 1.8e-20 2.4e-19 1.0e+00 100 C1orf84 FOXJ3 SLFNL1
11 1 45278094 46664249 1 1 1.2e-07 1.2e-06 3.4e-01 96 MMACHC
12 1 47997898 49629562 3 1 6.1e-08 5.1e-09 7.0e-09 2 RP5-1024N4.4
13 1 56260814 57805550 1 1 3.4e-12 3.1e-17 9.2e-14 22 PPAP2B
14 1 59073430 60921087 1 1 6.0e-14 8.7e-24 2.1e-13 47 FGGY
15 1 66304567 67938108 2 1 1.1e-10 1.2e-10 1.7e-01 96 SGIP1
16 1 88453303 90145331 5 1 1.3e-19 2.2e-21 9.0e-04 88 GTF2B
17 1 112312154 114367116 10 6 2.6e-25 3.0e-33 0.0e+00 -1930 LRIG2 RHOC SLC16A1 WNT2B
18 1 150008790 151786372 2 1 6.5e-08 6.1e-07 2.1e-05 27 GABPB2
19 1 156010787 157406190 1 1 3.8e-08 8.1e-08 6.5e-05 45 MRPL24
20 1 168375973 170032254 3 4 1.3e-10 6.6e-11 3.0e-10 7 ATP1B1 BLZF1 NME7
21 1 183961643 185416670 1 1 5.6e-09 4.0e-11 5.2e-06 52 EDEM3
22 1 195927451 197414097 2 1 1.1e-08 2.4e-09 2.8e-03 75 CFHR4
23 1 209059239 210729897 3 1 1.2e-08 3.9e-10 1.4e-05 52 TRAF3IP3
24 1 226488826 229344237 12 2 6.6e-15 3.2e-20 6.4e-08 66 IBA57 RP5-1087E8.3
25 1 230142626 231548480 3 2 6.1e-31 1.7e-29 1.0e+00 100 AGT
26 2 19492579 20908767 1 1 7.1e-12 1.8e-20 8.0e-12 46 MATN3
27 2 23453834 26068509 9 2 2.5e-20 2.3e-16 6.3e-01 100 ADCY3 UBXN2A
28 2 26624843 29344127 9 4 4.8e-09 2.7e-47 4.0e-38 20 CGREF1 IFT172 RP11-373D23.3
29 2 36726921 38571255 4 1 1.9e-14 6.2e-17 6.0e-08 58 PRKD3
30 2 41877732 44242779 8 5 9.9e-14 7.8e-15 2.0e-04 77 AC010883.5 FTOP1 HAAO KCNG3 PLEKHH2
31 2 55079242 56843605 3 1 1.9e-09 1.4e-11 1.0e-13 -21 PNPT1
32 2 62658256 66055613 8 2 9.8e-22 7.5e-22 1.0e+00 100 CEP68 WDPCP
33 2 67654113 70310878 5 2 6.1e-12 7.0e-12 3.0e-13 -13 GFPT1 PPP3R1
34 2 72774203 74187703 3 1 1.3e-08 1.8e-07 6.6e-01 99 FBXO41
35 2 84662093 87126250 8 3 1.8e-14 1.4e-13 6.4e-01 100 ATOH8 MRPL35 TCF7L1
36 2 111957073 113572357 2 1 3.8e-09 4.1e-09 1.0e+00 100 TMEM87B
37 2 113667753 115095488 3 1 8.0e-12 6.1e-12 3.4e-02 90 RABL2A
38 2 128601766 129196810 1 1 6.5e-08 3.8e-07 2.2e-01 94 UGGT1
39 2 134979415 136403272 1 1 1.6e-07 6.7e-07 1.2e-01 90 CCNT2
40 2 163760604 166170073 2 3 1.0e-14 1.5e-54 2.7e-37 33 FIGN GRB14
41 2 169860718 171256597 1 1 2.7e-07 2.5e-07 1.0e+00 100 PHOSPHO2
42 2 171683107 173114238 1 1 1.5e-07 1.7e-05 8.5e-02 84 CYBRD1
43 2 174238261 176247301 3 2 2.1e-10 1.0e-10 5.8e-01 99 OLA1 WIPF1
44 2 176342243 177746117 2 1 8.0e-11 2.8e-13 4.0e-04 76 HOXD-AS1
45 2 179617370 182636467 2 2 1.5e-08 2.8e-09 6.8e-02 91 UBE2E3 ZNF385B
46 2 190225250 192525536 8 2 4.4e-13 2.5e-13 1.7e-01 96 GLS HIBCH
47 2 200086752 201571143 3 1 1.2e-07 4.5e-10 7.0e-05 59 C2orf69
48 2 202952678 204549680 2 1 4.0e-13 1.5e-13 1.0e+00 100 CARF
49 2 215101843 216908910 2 1 3.1e-10 8.3e-23 4.0e-16 31 ABCA12
50 2 217967913 219878756 6 2 1.2e-15 1.8e-14 3.2e-10 33 TMBIM1 TNS1
51 2 241356797 242767801 1 1 7.4e-08 6.1e-06 9.0e-01 100 PASK
52 3 10617048 13321852 3 2 1.0e-18 8.0e-20 4.8e-03 90 MKRN2 VGLL4
53 3 19512074 20920840 1 1 1.5e-07 1.6e-06 1.6e-02 75 SGOL1
54 3 26563909 28211713 2 3 2.4e-36 3.7e-36 2.3e-01 99 SLC4A7
55 3 36794597 38562579 1 1 1.6e-07 1.2e-10 1.8e-04 66 ITGA9
56 3 40594264 42967174 2 1 3.3e-10 3.6e-10 3.1e-01 97 ULK4
57 3 46730749 50455031 18 2 9.6e-22 1.9e-21 1.0e+00 100 NME6 UBA7
58 3 52047421 53489090 1 1 9.1e-08 3.5e-08 1.2e-04 52 NEK4
59 3 65732113 67154946 1 1 1.3e-07 1.4e-09 2.5e-03 75 LRIG1
60 3 84317575 86808226 1 1 5.5e-11 2.4e-14 1.3e-05 67 CADM2
61 3 120924204 122973506 4 2 4.4e-10 5.2e-10 5.0e-01 99 FAM162A SLC15A2
62 3 123792729 125314016 1 1 7.8e-22 3.8e-20 1.7e-01 98 ITGB5
63 3 132957293 134987090 5 2 3.8e-18 6.9e-21 9.2e-03 92 RPL39P5 RYK
64 3 135273949 136746974 2 1 1.4e-08 7.2e-09 1.0e+00 100 PCCB
65 3 137189600 138819532 2 1 1.9e-11 5.9e-11 1.0e+00 100 MRAS
66 3 153142317 154733231 3 1 6.5e-12 5.2e-12 3.6e-11 8 DHX36
67 3 157125828 159106064 3 1 5.1e-11 1.5e-08 7.7e-01 100 RP11-379F4.7
68 3 159248823 161788101 8 2 9.3e-13 4.9e-11 8.0e-01 100 C3orf57 TRIM59
69 3 166760899 168242895 1 1 3.3e-08 2.0e-06 3.4e-02 80 SERPINI1
70 3 168789705 170198967 3 1 1.9e-13 1.7e-27 5.7e-24 14 ACTRT3
71 3 182826316 184429414 3 1 9.5e-12 4.7e-09 5.7e-01 99 MAP6D1
72 3 184607480 186049228 1 1 5.6e-12 6.4e-13 6.1e-03 86 SENP2
73 3 195279119 197080597 5 2 2.6e-10 3.9e-11 1.9e-01 96 NRROS RNF168
74 4 1024287 3740612 7 6 3.0e-10 8.9e-09 1.5e-64 -770 FAM193A FGFR3 MXD4 POLN RGS12
75 4 7060959 8621167 2 1 3.7e-09 3.7e-09 1.2e-01 93 AFAP1
76 4 14310407 15767752 1 1 9.7e-12 1.8e-10 1.7e-02 86 CPEB2
77 4 16922182 18507692 3 2 5.6e-14 1.2e-12 7.7e-03 86 DCAF16 MED28
78 4 26383043 26986737 1 1 8.6e-09 4.4e-12 1.2e-04 69 TBC1D19
79 4 47645550 53598975 9 1 2.0e-11 9.7e-12 1.0e+00 100 OCIAD1
80 4 55517005 57110821 5 2 2.3e-15 6.7e-11 9.6e-01 100 PDCL2 SRD5A3
81 4 69893854 70120699 1 1 1.3e-08 8.6e-09 1.0e+00 100 UGT2B7
82 4 76539958 78026629 1 1 8.0e-08 7.6e-11 4.4e-05 61 CCDC158
83 4 80407869 82578407 3 3 1.0e-39 5.3e-115 7.1e-20 84 C4orf22 FGF5 PRDM8
84 4 83124080 84515968 1 1 3.0e-08 6.7e-07 8.3e-01 100 THAP9-AS1
85 4 85698680 87621473 2 1 5.0e-27 8.7e-24 9.1e-01 100 RP13-514E23.2
86 4 101579972 102968082 2 1 7.7e-08 3.1e-21 8.1e-17 22 AP001816.1
87 4 106265432 107966499 2 1 9.2e-09 9.9e-12 1.4e-09 21 TBCK
88 4 108661802 109204013 1 1 2.9e-08 4.1e-08 2.7e-03 70 HADH
89 4 110590479 112179424 1 2 8.2e-12 4.0e-17 3.1e-04 82 ENPEP
90 4 119605671 120922444 1 1 8.4e-09 4.3e-08 3.1e-02 84 C4orf3
91 4 143569058 145092857 1 1 5.7e-12 2.9e-14 9.4e-05 74 GAB1
92 4 145982563 147552337 1 1 8.2e-16 1.1e-15 3.8e-02 93 ZNF827
93 4 155890241 157568422 4 3 1.5e-32 7.6e-30 4.9e-06 84 CTSO GUCY1A3 RP11-588K22.2
94 5 32015725 34125961 2 2 3.8e-14 9.5e-82 6.5e-66 20 CTD-2203K17.1 NPR3
95 5 42908384 44403631 1 1 1.5e-07 7.0e-05 3.5e-05 -8 NNT
96 5 52157374 53672849 1 1 3.2e-09 3.2e-16 9.9e-18 -10 NDUFS4
97 5 57547419 58039977 1 1 1.5e-07 1.7e-07 2.6e-02 82 GAPT
98 5 60903201 62529686 3 1 6.6e-14 8.0e-13 4.5e-01 99 IPO11
99 5 70709459 72201058 1 1 1.4e-09 8.8e-08 9.8e-01 100 MAP1B
100 5 77380723 78977661 1 1 3.9e-08 1.5e-14 4.6e-11 27 ARSB
101 5 95416676 97065386 2 6 1.5e-08 2.5e-10 NaN NaN AC008865.1 ERAP1
102 5 107390303 109224099 1 1 3.6e-09 7.3e-10 2.9e-03 77 FER
103 5 117683871 119277107 1 1 2.3e-08 4.7e-06 1.1e-02 69 DMXL1
104 5 121488203 123449266 5 2 1.1e-19 5.2e-21 1.1e-08 63 CSNK1G3 SNX24
105 5 126587995 128220643 4 3 2.5e-14 9.8e-24 2.1e-07 73 CTC-228N24.3 FLJ33630 SLC12A2
106 5 131699867 133140038 2 1 9.2e-11 3.2e-10 1.0e+00 100 ZCCHC10
107 5 138036255 142404354 35 4 1.7e-14 2.3e-13 4.4e-01 99 DNAJC18 NDUFA2 PCDHA6 SPRY4
108 5 147012186 149338157 5 5 4.0e-14 3.7e-18 2.3e-06 70 ABLIM3 ADRB2 FBXO38 HTR4
109 5 154607639 157879489 2 2 3.2e-09 4.8e-33 3.3e-36 -10 LSM11 SGCD
110 5 172620700 174088123 1 1 3.7e-11 1.3e-11 1.0e+00 100 CPEB4
111 5 178640760 180195862 1 1 2.6e-09 2.4e-06 1.7e-01 92 RNF130
112 6 12020241 13990267 2 1 3.8e-10 3.2e-11 1.8e-02 87 RP1-257A7.5
113 6 34747603 36581149 4 4 1.1e-10 2.8e-11 7.6e-03 84 SRPK1 TCP11 TEAD3
114 6 42052577 44034691 5 2 1.2e-17 1.7e-18 1.0e+00 100 MEA1 ZNF318
115 6 53645566 54379332 1 1 1.8e-07 1.6e-07 7.2e-03 74 C6orf142
116 6 55222696 56954550 1 1 4.6e-13 1.6e-12 5.2e-01 99 COL21A1
117 6 78880271 80486611 2 1 3.1e-16 1.7e-15 1.0e+00 100 IRAK1BP1
118 6 95831017 97979053 5 1 3.5e-16 1.8e-16 1.0e+00 100 UFL1
119 6 116950734 119578310 5 2 5.3e-21 1.2e-11 5.1e-01 99 GOPC PLN
120 6 125970401 127355237 1 1 7.7e-11 8.7e-54 3.6e-45 17 CENPW
121 6 133575570 135005715 3 2 9.7e-08 3.2e-09 1.7e-01 94 TBPL1 TCF21
122 7 511203 1796562 1 1 2.5e-07 1.5e-14 5.9e-14 5 GPR146
123 7 1854263 3264728 1 1 4.9e-13 6.7e-13 1.0e+00 100 LFNG
124 7 5726022 7141565 1 1 4.2e-08 9.9e-06 7.4e-01 100 RAC1
125 7 23913624 25508637 2 1 5.1e-10 8.0e-10 1.5e-01 94 MPP6
126 7 26010759 28401337 4 4 1.8e-29 1.4e-40 3.1e-04 93 HIBADH HOXA10 SKAP2
127 7 45709404 46210616 1 1 6.6e-14 1.8e-19 1.5e-07 66 IGFBP3
128 7 46616776 48315796 1 2 2.7e-10 9.3e-10 1.6e-01 95 TNS3
129 7 55334240 56823372 2 1 2.1e-08 2.1e-08 1.0e+00 100 CCT6A
130 7 74339397 75842792 6 1 3.8e-08 1.9e-07 2.8e-01 96 TRIM73
131 7 76506844 77966572 2 1 8.2e-10 1.9e-09 1.7e-02 84 PTPN12
132 7 91046993 93160671 10 2 1.3e-23 8.5e-26 1.1e-03 90 CDK6 PEX1
133 8 164984 2381004 6 3 1.2e-10 3.4e-07 1.1e-01 90 CLN8 ERICH1 RPL23AP53
134 8 21758119 23678000 2 2 2.1e-11 4.5e-11 1.0e+00 100 C8orf58 SLC25A37
135 8 25453126 26151802 1 1 9.3e-08 1.6e-31 4.1e-26 18 EBF2
136 8 37329315 38989813 10 1 9.0e-15 1.6e-14 4.8e-02 93 DDHD2
137 8 41585384 43081251 1 1 4.2e-10 2.9e-09 3.9e-01 98 SLC20A2
138 8 82017372 83452091 1 1 3.3e-09 3.6e-12 5.3e-05 66 SNX16
139 8 95213858 96825195 2 1 3.7e-09 2.4e-13 5.1e-12 11 TP53INP1
140 8 100887350 102369781 1 1 2.4e-15 3.1e-15 1.0e+00 100 SNX31
141 8 119737284 121136001 1 1 1.1e-17 3.5e-17 3.6e-04 82 NOV
142 8 140840550 144515639 7 4 9.0e-15 4.7e-19 2.3e-05 78 ARC CASC7 DENND3 TSNARE1
143 9 108998 883226 1 1 1.3e-07 2.1e-08 3.1e-02 85 CBWD1
144 9 18674055 20068518 1 1 2.6e-08 5.3e-07 6.5e-01 99 RP11-513M16.7
145 9 33487023 34942510 2 2 1.7e-08 1.3e-06 1.0e-01 88 PRSS3 UBAP1
146 9 35656875 36147128 1 1 8.7e-08 7.5e-06 2.7e-02 76 HRCT1
147 9 115471346 117517897 3 2 5.2e-10 5.0e-11 1.0e+00 100 POLE3 ZNF618
148 9 122669622 124304612 3 2 1.6e-08 2.5e-07 6.7e-01 99 MEGF9 PSMD5-AS1
149 9 125006622 129422783 11 14 1.6e-13 5.2e-13 NaN NaN GAPVD1 GOLGA1 MAPKAP1 OLFML2A PBX3 PPP6C PSMB7 RABGAP1
150 9 133571587 135074103 1 1 1.1e-09 3.9e-06 2.9e-02 78 PRRC2B
151 9 135581102 137019776 1 1 9.2e-09 2.5e-19 4.6e-12 41 ADAMTS13
152 10 18221643 19637020 3 2 4.5e-35 3.9e-53 2.4e-44 17 CACNB2 NSUN6
153 10 31402767 33506928 3 1 8.5e-14 9.8e-13 8.1e-02 94 KIF5B
154 10 59329755 65606229 10 8 2.7e-19 1.1e-36 1.8e-36 1 ADO ARID5B BICC1 C10orf107 CCDC6 CISD1 RHOBTB1 TMEM26
155 10 68861272 70532990 3 1 6.9e-13 3.0e-12 5.3e-01 99 SIRT1
156 10 74206576 77160682 20 1 1.8e-25 9.0e-19 5.6e-02 95 FUT11
157 10 81208964 82984432 6 1 2.3e-10 6.3e-12 6.8e-04 76 DYDC2
158 10 93754543 97524313 7 10 1.7e-21 1.9e-37 NaN NaN CYP2C8 HELLS HHEX NOC3L
159 10 101548177 106371784 30 16 1.8e-52 2.3e-60 1.0e+00 100 C10orf26 CNNM2 DPCD FBXW4 LDB1 OBFC1 POLL RP11-179B2.2 SEC31B SFXN2 SFXN3 TMEM180 TRIM8
160 10 113675738 116178891 4 4 2.9e-19 6.0e-33 3.1e-14 60 ADRB1 C10orf118 GPAM TCF7L2
161 10 120954350 122399277 1 1 3.8e-08 2.2e-07 5.1e-08 -10 SEC23IP
162 10 123438113 124973104 2 1 4.6e-10 1.9e-11 1.5e-03 78 HTRA1
163 10 133048749 134466163 1 1 5.1e-09 4.4e-10 1.1e-09 5 PPP2R2D
164 11 350917 2705175 7 7 2.2e-50 2.2e-55 NaN NaN LSP1 RP13-870H17.3 TNNI2 TNNT3
165 11 8458749 11414338 7 5 2.4e-35 7.2e-33 5.5e-05 89 ADM MRVI1 RNF141 ST5 SWAP70
166 11 12611333 18106069 13 5 3.8e-26 4.0e-29 4.7e-12 62 ARNTL COPB1 DKFZp686O24166 SOX6
167 11 21661311 23094558 1 1 2.3e-08 4.2e-12 1.5e-09 24 SLC17A6
168 11 27139110 27734420 1 1 1.6e-09 1.0e-14 1.6e-08 47 LGR4
169 11 29646947 31048683 2 1 3.4e-14 5.9e-12 2.2e-01 97 ARL14EP
170 11 31286472 32044946 1 1 1.7e-08 6.4e-10 4.0e-03 78 ELP4
171 11 45258966 48783497 26 5 3.8e-44 6.3e-37 NaN NaN ACP2 MYBPC3 NUP160 PHF21A
172 11 50001972 50495703 1 1 4.5e-17 2.9e-24 3.5e-13 49 LOC441601
173 11 56253681 58178587 7 2 8.4e-21 1.1e-15 4.1e-13 18 LRRC55 MED19
174 11 62922117 66333072 19 10 1.3e-20 7.6e-19 NaN NaN FIBP GPR137 KAT5 MARK2 NAALADL1 SIPA1 SNX32
175 11 75453877 76959598 2 1 1.6e-09 2.0e-12 1.3e-04 70 C11orf30
176 11 99859184 101559718 2 1 4.2e-83 3.0e-81 1.0e+00 100 ARHGAP42
177 11 106485489 108027561 3 1 9.7e-24 3.5e-30 1.2e-08 75 RP11-819C21.1
178 11 110721187 112491227 7 1 1.5e-12 1.3e-12 1.0e+00 100 C11orf1
179 11 116352008 117800682 3 1 3.2e-10 3.1e-11 4.4e-03 82 SIDT2
180 11 119388572 120797604 1 1 1.9e-08 4.1e-09 2.3e-07 23 OAF
181 12 327421 1795687 1 1 6.2e-11 2.0e-08 4.7e-01 98 RAD52
182 12 12175854 13658205 2 1 2.6e-10 3.8e-14 3.4e-16 -16 APOLD1
183 12 26027207 28538435 5 2 2.1e-10 4.5e-12 2.7e-10 17 BHLHE41 MED21
184 12 47671905 51912062 21 10 1.3e-23 2.7e-23 1.0e+00 100 AQP5 ATF1 CERS5 DIP2B FMNL3 HDAC7 LIMA1 RP4-605O3.4 SENP1
185 12 52702633 54134291 1 1 1.5e-09 2.7e-14 3.6e-08 48 EIF4B
186 12 54158993 54760824 4 1 1.0e-22 9.7e-26 1.2e-04 86 HOXC8
187 12 79275054 80775817 1 1 4.8e-08 2.4e-12 5.5e-10 22 PAWR
188 12 89116708 90799212 5 7 7.1e-51 5.8e-71 NaN NaN ATP2B1 GALNT4 POC1B RP11-981P6.1
189 12 109231851 113517494 29 9 9.6e-54 8.1e-58 NaN NaN ADAM1A BRAP GLTP MMAB NAA25 SH2B3 TMEM116 TRAFD1 TRPV4
190 12 120044549 123701010 6 4 6.9e-11 4.4e-08 6.5e-01 99 KDM2B RSRC2 SIRT4 WDR66
191 13 29386474 30865365 1 1 2.1e-07 6.6e-13 3.5e-07 50 SLC7A1
192 13 41092698 42640341 2 1 1.4e-11 2.0e-10 6.1e-02 91 NAA16
193 13 95603622 97402915 2 1 2.2e-08 2.3e-07 4.1e-03 69 DNAJC3-AS1
194 13 112931650 115106996 4 2 1.0e-22 1.4e-21 1.0e+00 100 MCF2L-AS1 UPF3A
195 14 22670975 24147787 4 2 1.4e-12 3.8e-12 7.0e-07 49 RBM23 RP11-298I3.1
196 14 35173418 36972226 2 5 4.3e-13 4.8e-14 NaN NaN NFKBIA RALGAPA1
197 14 50199169 51830366 2 1 1.4e-09 6.6e-10 1.0e+00 100 SAV1
198 14 52408380 53940700 3 2 2.4e-12 5.0e-17 4.0e-09 51 RP11-841O20.2 STYX
199 14 69639433 72273020 2 2 1.2e-09 3.4e-10 1.0e+00 100 PCNX SMOC1
200 14 73012484 76340208 18 3 2.0e-14 1.7e-10 7.5e-01 100 PNMA1 RP4-647C14.2 RPS6KL1
201 14 99421061 101101120 4 3 2.2e-11 1.3e-10 4.3e-01 98 CYP46A1 DEGS2 EML1
202 15 39530508 42957373 25 9 7.2e-20 8.2e-19 NaN NaN BAHD1 EIF2AK4 EXD1 GCHFR INO80 MAPKBP1 OIP5-AS1 PLA2G4B RTF1
203 15 50147368 51678028 2 1 1.6e-13 4.3e-14 3.5e-02 92 TRPM7
204 15 62636766 64123980 4 1 9.6e-12 1.6e-11 1.0e+00 100 RP11-244F12.3
205 15 66662107 68183665 1 1 9.1e-08 2.0e-10 6.4e-11 -6 SMAD3
206 15 73933444 76108550 15 1 1.6e-44 7.8e-43 4.9e-02 98 CSK
207 15 80272818 81737095 2 2 8.7e-18 2.9e-23 1.3e-02 94 ABHD17C FAM108C1
208 15 84945185 86489699 2 1 1.8e-08 4.4e-12 1.5e-05 61 PDE8A
209 15 90712555 92187978 6 8 2.9e-70 1.2e-58 NaN NaN FES FURIN HDDC3 UNC45A
210 15 92463303 94048686 1 1 2.6e-07 8.1e-08 1.0e+00 100 FAM174B
211 16 661142 5627737 31 24 3.8e-23 3.0e-20 NaN NaN AC006111.1 ADCY9 ANKS3 CCDC154 CLCN7 GFER GLYR1 HAGH LA16c-358B7.3 LA16c-390E6.4 NAT15 NUDT16L1 RNPS1 ROGDI RPS2 SEPT12 SLC9A3R2 UBE2I UBN1 ZNF500 ZNF598
212 16 11231857 12767048 2 1 4.7e-08 4.4e-10 1.1e-04 61 RP11-166B2.1
213 16 19937475 21352507 4 1 5.9e-09 4.0e-17 2.3e-17 -2 DCUN1D3
214 16 24162204 25620010 1 1 1.0e-19 2.5e-19 1.0e+00 100 SLC5A11
215 16 29682945 31077409 3 1 8.3e-10 5.0e-10 1.0e+00 100 MYLPF
216 16 52222053 52828325 1 1 2.0e-08 1.2e-08 6.2e-02 89 TOX3
217 16 65813302 67691515 6 1 8.6e-10 1.7e-09 1.0e+00 100 CES2
218 16 69062879 72569466 13 3 7.9e-11 8.6e-15 2.2e-06 63 ATXN1L CMTR2 PDXDC2P
219 16 74270536 76197034 6 2 2.7e-27 9.5e-29 1.0e+00 100 TMEM170A ZFP1
220 16 81966047 84527021 1 1 3.5e-10 2.1e-09 4.1e-01 98 CDH13
221 16 89281093 90172696 1 1 1.4e-09 1.5e-05 4.4e-04 34 MC1R
222 17 554080 3287175 10 4 1.3e-18 3.4e-22 8.1e-05 83 CRK PAFAH1B1 SMG6 WDR81
223 17 5664752 9070646 35 9 1.1e-20 5.7e-18 1.0e+00 100 ACADVL ACAP1 C17orf68 CYB5D1 DULLARD ELP5 KIAA0753 SENP3 SLC2A4
224 17 17051974 18923818 11 2 9.2e-12 3.9e-10 3.5e-04 67 TOM1L2 TOP3A
225 17 19142226 20522444 2 1 1.4e-09 1.5e-08 4.2e-01 98 RP11-78O7.2
226 17 28398977 29844909 2 1 4.9e-08 4.6e-08 2.6e-05 41 CRLF3
227 17 29959697 31506495 2 1 7.1e-09 2.0e-08 2.5e-01 96 C17orf75
228 17 39420932 41393295 2 1 1.0e-07 4.3e-07 2.2e-02 79 CNP
229 17 41946180 48347817 76 36 2.4e-38 1.4e-48 NaN NaN AC015936.3 AC091133.1 ADAM11 ARL17A ARL17B C17orf104 C17orf69 CBX1 EFCAB13 GOSR2 HOXB3 HOXB4 HOXB9 ITGB3 KANSL1 KIF18B LRRC46 NMT1 NSF NSFP1 PLCD3 RP11-156P1.3 RP11-6N17.6 RP5-1029K10.2 SCRN2 SNF8 SNX11 UBE2Z
230 17 55704465 58660283 5 2 3.0e-11 7.5e-10 2.3e-01 96 AC099850.1 RPS6KB1
231 17 58828402 63353913 12 5 1.2e-24 6.5e-22 1.9e-02 94 ACE DDX5 MARCH10 RP11-332H18.4 TEX2
232 17 73128150 74629867 10 1 6.2e-13 1.9e-12 1.7e-01 96 TRIM47
233 17 75977988 77462467 3 1 7.1e-15 5.9e-14 9.6e-02 95 CYTH1
234 17 78467411 80023050 2 2 1.9e-09 5.1e-10 1.0e+00 100 AZI1 RP11-1055B8.4
235 18 69836 1512239 4 3 5.8e-16 4.2e-16 1.0e+00 100 TYMS YES1
236 18 46650437 48954160 2 2 2.7e-11 4.1e-13 2.4e-11 15 MAPK4 MYO5B
237 18 51553172 52058680 1 1 5.4e-08 9.5e-09 7.7e-04 66 POLI
238 18 55013074 56767327 1 1 1.2e-09 2.2e-09 1.0e+00 100 NEDD4L
239 19 1086043 2947152 6 2 2.6e-16 2.0e-16 1.0e+00 100 ATP8B3 PLEKHJ1
240 19 6374813 7771742 1 1 1.8e-10 8.9e-23 4.8e-22 3 ZNF557
241 19 9637688 13237502 6 6 1.6e-18 5.6e-19 5.1e-08 62 DOCK6 KANK2 S1PR2 SMARCA4 ZNF443
242 19 16462417 18007950 3 1 4.7e-15 6.9e-17 1.0e+00 100 CTD-3032J10.3
243 19 20885811 22643745 3 1 1.2e-12 7.7e-09 1.6e-03 70 ZNF100
244 19 33630693 34258707 1 1 6.0e-08 1.6e-09 6.3e-05 56 PEPD
245 19 36712656 38948356 6 1 9.1e-10 2.0e-07 4.5e-01 98 ZNF585B
246 19 45585167 46994833 4 1 1.9e-14 2.2e-13 1.8e-01 97 AC074212.6
247 19 48464978 50108983 9 1 3.3e-15 2.1e-15 7.9e-02 95 RASIP1
248 20 7847156 9112333 1 1 3.8e-11 8.5e-18 3.0e-09 52 PLCB1
249 20 18506005 20398583 1 1 1.5e-07 1.1e-07 2.1e-07 5 SLC24A3
250 20 29833609 32083711 6 2 6.3e-12 4.4e-15 5.0e-06 66 COMMD7 HM13
251 20 33110042 34829868 6 1 3.0e-10 4.7e-09 7.3e-01 100 UQCC1
252 20 39782899 40490356 1 1 1.5e-07 4.4e-11 5.3e-05 62 CHD6
253 20 42040938 43508687 1 2 8.4e-11 3.9e-14 9.2e-05 73 JPH2
254 20 46551079 48603940 5 1 1.2e-11 2.4e-18 1.0e-08 57 PREX1
255 20 56858751 58262841 5 8 5.3e-23 2.8e-42 NaN NaN CTSZ NELFCD TH1L TUBB1 ZNF831
256 20 61522825 62912463 12 11 2.8e-18 9.9e-16 NaN NaN LIME1 OPRL1 RGS19 SLC2A4RG ZBTB46
257 21 34316133 35954601 1 1 2.3e-07 2.4e-09 1.9e-03 73 ITSN1
258 21 44251223 45879403 3 1 1.0e-10 4.5e-13 1.2e-12 4 PDXK
259 22 19262852 20330744 3 5 9.7e-12 3.4e-12 1.0e+00 100 AC006547.13 AC006547.14 ARVCF
260 22 29033458 29704125 2 2 7.0e-13 1.3e-14 4.8e-03 87 C22orf31 ZNRF3
261 22 37394391 38907849 3 1 3.5e-09 5.2e-08 6.8e-01 99 TRIOBP
262 22 40195017 41047764 3 1 2.4e-10 4.3e-08 9.5e-01 100 SGSM3
263 22 41840407 43232818 1 1 1.1e-10 1.1e-08 1.7e-01 94 CYP2D7P1
264 22 49939309 51219006 1 1 1.3e-07 6.9e-08 3.8e-05 42 TRABD

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Bipolar Disorder (2018) 1.19 1 0 0.0 0.00 1.0e+00 NEK4
Bipolar Disorder or Schizophrenia 1.52 16 10 22.2 -0.45 4.7e-02 C2orf69 CGREF1 CNNM2 CYP2D7P1 DDHD2 FES FURIN GALNT4 HDDC3 MARK2 MPP6 NDUFA2 NEK4 NSUN6 TMEM180 ZMYM4
Depressed Affect (Nagel 2018) 1.25 6 5 11.1 -0.03 9.6e-01 ACP2 ARL17B ARNTL NSF NUP160 RERE
Depression (Nagel 2018) 1.20 3 0 0.0 0.00 1.0e+00 NDUFA2 PCCB RERE
Intelligence (Savage-Jansen 2018) 1.16 19 11 24.4 -0.14 5.6e-01 AC008865.1 ARL17A ATXN1L C17orf68 C2orf69 DCAF16 EDEM3 FBXO41 FBXW4 KANSL1 MYBPC3 NDUFA2 NEK4 NSF NSFP1 PREX1 SLC5A11 TRIOBP UBA7
Neuroticism (Nagel 2018) 1.47 15 10 22.2 -0.19 4.8e-01 ACP2 ADM ARL17A ARL17B ARNTL CNNM2 KANSL1 MMAB NSF NSFP1 NUP160 PCCB PPP6C RERE RNF130
Schizophrenia (2018) 1.61 12 5 11.1 -0.37 1.5e-01 C2orf69 CNNM2 CYP2D7P1 FES FURIN HDDC3 MARK2 NDUFA2 PCCB PCNX RERE ZMYM4
Worry (Nagel 2018) 1.53 14 7 15.6 -0.21 4.3e-01 ARL17A ARL17B CADM2 CNNM2 GOLGA1 MMAB NEK4 NSF NUP160 PCCB PEPD PPP6C RP11-78O7.2 SMG6
Alzheimer’s Disease (including proxy) 1.07 2 1 2.2 0.00 1.0e+00 ACE PRKD3
Crohns Disease (2017) 1.31 9 7 15.6 0.36 3.4e-01 AC008865.1 ADO C11orf30 RASIP1 RP11-373D23.3 SLC20A2 SLC2A4RG SMAD3 UBA7
Irritable Bowel Disease (IBD) 1.38 15 7 15.6 0.42 1.1e-01 AC008865.1 ADCY3 C11orf30 GABPB2 HHEX LSP1 NADK RGS19 RP11-373D23.3 SLC20A2 SLC2A4RG SMAD3 TMBIM1 TNNI2 UBA7
Ulcerative Colitis (UC) 1.33 5 2 4.4 0.87 2.2e-03 LSP1 OPRL1 RGS19 TNNI2 UBA7
Major Depression (MDD) 1.30 1 0 0.0 0.00 1.0e+00 FES
Reaction Time 1.56 10 8 17.8 -0.13 7.1e-01 ARL17A BRAP C2orf69 KANSL1 NAA25 NSF NSFP1 OLA1 PHF21A SH2B3
Verbal and Numeric Reasoning (VNR) 1.21 10 4 8.9 -0.49 1.5e-01 ATXN1L C17orf68 C2orf69 DCAF16 FBXO41 MYBPC3 NEK4 PREX1 SLC5A11 UBA7
Breast Cancer 2.27 20 9 20.0 0.13 5.1e-01 ADCY3 ADCY9 CPEB4 CSK CTC-228N24.3 FES FIBP FURIN HDDC3 LDB1 MMACHC NSF SGSM3 SLC4A7 SNX32 TCF7L2 TNNT3 TOM1L2 TOX3 ZCCHC10
Ovarian Cancer 1.23 3 1 2.2 0.00 1.0e+00 ARL17B HOXB4 RP11-6N17.6
Prostate Cancer 1.34 2 2 4.4 0.00 1.0e+00 C11orf30 SKAP2
Age at First Birth 1.14 1 1 2.2 0.00 1.0e+00 UBA7
Bipolar Disorder (2011) 1.55 1 0 0.0 0.00 1.0e+00 NEK4
Body Mass Index (BMI) (2010) 1.43 2 1 2.2 0.00 1.0e+00 MYBPC3 TRIM73
Coronary Artery Disease (CAD) 1.98 5 1 2.2 0.39 5.2e-01 CNNM2 MRAS PPAP2B RP1-257A7.5 TCF21
Crohns Disease (2012) 1.24 5 4 8.9 -0.17 7.8e-01 AC008865.1 RASIP1 SLC2A4RG SMAD3 UBA7
Fasting Glucose 1.34 2 2 4.4 0.00 1.0e+00 ACP2 CGREF1
HbA1C 1.01 1 0 0.0 0.00 1.0e+00 ADAM1A
HDL Cholesterol 1.37 10 3 6.7 -0.62 4.3e-02 ACP2 ADRB1 GRB14 MYBPC3 MYO5B PIGV RAC1 RP11-244F12.3 SIPA1 SNX32
LDL Cholesterol 1.33 6 2 4.4 -0.22 6.7e-01 BRAP MKRN2 RASIP1 SCRN2 SH2B3 SMARCA4
Lupus 1.20 3 0 0.0 0.00 1.0e+00 ARID5B PLEKHJ1 TCP11
Neuroticism (2016) 1.22 2 1 2.2 0.00 1.0e+00 ADM NUP160
Primary Biliary Cirrhosis 1.17 2 1 2.2 0.00 1.0e+00 SH2B3 TRIM59
Rheumatoid Arthritis 1.23 2 1 2.2 0.00 1.0e+00 ARID5B SH2B3
Schizophrenia (2014) 1.58 14 7 15.6 -0.34 1.7e-01 C2orf69 CERS5 CGREF1 CNNM2 CYP2D7P1 FES FURIN HDDC3 MARK2 NEK4 PCCB PCNX RERE TOM1L2
Triglycerides 1.27 7 5 11.1 0.95 1.3e-03 CGREF1 GRB14 IFT172 RGS12 RP11-373D23.3 SIDT2 ZNF557
Type 2 Diabetes (T2D) (2012) 1.49 3 2 4.4 0.00 1.0e+00 HHEX LRIG1 TCF7L2
Ulcerative Colitis 1.26 3 0 0.0 0.00 1.0e+00 LSP1 TMBIM1 TNNI2
Blood Eosinophil Count 1.67 70 53 117.8 0.43 1.3e-04 AC006547.13 AC006547.14 AC010883.5 AC074212.6 ACADVL ACAP1 ADAM1A ADRB2 ARL17B ARVCF BRAP C11orf30 CDK6 CERS5 CLIC4 CPEB4 CTC-228N24.3 DCUN1D3 EFCAB13 ELP5 FIBP FLJ33630 FOXJ3 FUT11 GABPB2 GALNT4 GLTP HHEX HTR4 KAT5 LIMA1 MED19 NAA25 NAT15 NEK4 NFKBIA NNT NSF OIP5-AS1 PDXK PHACTR4 PIGV PLCD3 POC1B PSMB7 RERE RP11-156P1.3 RP11-981P6.1 RP5-1029K10.2 RTF1 SFXN2 SH2B3 SIPA1 SMAD3 SNF8 SNX32 SPRY4 TCP11 TEAD3 THAP9-AS1 TMEM116 TOM1L2 TP53INP1 TRAFD1 TRIM47 TRIM8 TRPV4 UBA7 UBE2Z ZNF831
Blood Platelet Count 1.91 129 98 217.8 0.09 2.9e-01 AC006547.13 AC006547.14 AC010883.5 AC015936.3 AC074212.6 ADAM11 ADAM1A ADAMTS13 ADO ANKS3 ARID5B ARL17A ARVCF ATF1 ATXN1L C10orf107 C4orf3 C8orf58 CARF CDK6 CERS5 CGREF1 CHD6 CLIC4 CRK CSK CTSZ DCAF16 DCUN1D3 DIP2B DKFZp686O24166 DNAJC18 DYDC2 EDEM3 ERAP1 FER FIBP GOSR2 GPAM GPR137 GTF2B HDAC7 HDDC3 HELLS HM13 IFT172 IPO11 IRAK1BP1 ITGA9 JPH2 KAT5 LDB1 LFNG LIMA1 LIME1 LRRC55 MAP6D1 MED28 MEGF9 MMACHC MPP6 MRPL24 MTHFR MYBPC3 NAA25 NEK4 NELFCD NMT1 NSFP1 NUDT16L1 OBFC1 OCIAD1 PAFAH1B1 PCCB PEX1 PHOSPHO2 PIGV PNMA1 POC1B PPAP2B PSMB7 PSMD5-AS1 RASIP1 RGS12 RHOBTB1 RHOC RNPS1 RP11-244F12.3 RP11-373D23.3 RP11-6N17.6 RP11-78O7.2 RP11-981P6.1 RP13-514E23.2 RP4-605O3.4 RP5-1029K10.2 RPS6KB1 RPS6KL1 SAV1 SENP1 SEPT12 SGCD SH2B3 SIDT2 SIPA1 SIRT1 SLC25A37 SLC2A4RG SLC4A7 SMG6 SNF8 SNX16 SNX32 TEAD3 TH1L TMBIM1 TMEM116 TMEM170A TRABD TRAF3IP3 TRIM8 TRPV4 TUBB1 UBE2Z UBN1 WDR66 WNT2B YES1 ZNF318 ZNF500
Blood Red Count 1.32 89 69 153.3 0.17 9.1e-02 AC010883.5 ACTRT3 ADAM1A ADM ARL17B ARNTL BRAP C17orf69 C1orf84 C2orf69 CBWD1 CCDC158 CLCN6 CLIC4 CNNM2 CPEB4 CRK CSK CTSZ CYB5D1 EIF2AK4 ELP4 EXD1 GCHFR GOSR2 GRB14 GTF2B HELLS HHEX HM13 HOXB4 HOXB9 IFT172 INO80 ITSN1 LRRC46 MAPKAP1 MAPKBP1 MC1R MKRN2 MMACHC MTHFR MYBPC3 MYLPF NAA16 NAA25 NEK4 NELFCD NME6 NOV NPPA NSF NUP160 OBFC1 PAWR PBX3 PDXK PEX1 PHF21A PLCD3 PLEKHH2 POLI RP11-156P1.3 RP11-332H18.4 RP11-6N17.6 RPS6KB1 RTF1 SCRN2 SENP1 SH2B3 SLC20A2 SLC2A4RG SLC9A3R2 SMOC1 ST5 TH1L TMEM116 TMEM87B TP53INP1 TRAFD1 TRIM8 TRIOBP TUBB1 UBA7 UBE2E3 ULK4 WDR66 ZNF100 ZNF443
Blood White Count 1.65 75 55 122.2 0.48 1.5e-06 AC006547.13 AC006547.14 AC010883.5 ACP2 ADAM1A ADRB2 APOLD1 ARHGAP42 ARVCF ATF1 BHLHE41 BRAP C10orf118 C1orf84 C4orf3 CCT6A CDK6 CERS5 CGREF1 CRK CSNK1G3 CTC-228N24.3 CYB5D1 DCAF16 DENND3 DMXL1 FBXO38 FER FES FLJ33630 FURIN GLYR1 HELLS HOXC8 HTR4 IFT172 LA16c-358B7.3 LIMA1 MC1R MYBPC3 NAA16 NAA25 NFKBIA NNT NUDT16L1 NUP160 PAWR PLA2G4B PLCB1 POLI PSMB7 RERE RP11-373D23.3 RP11-6N17.6 RP11-78O7.2 RP4-605O3.4 RP5-1029K10.2 RPS6KB1 RTF1 S1PR2 SGCD SGOL1 SH2B3 SIRT1 SLC5A11 SLC9A3R2 THAP9-AS1 TMEM116 TMEM87B TOM1L2 TRAF3IP3 TRAFD1 TRPM7 UBA7 UBE2E3
Heel T-Score 1.62 88 64 142.2 0.17 8.7e-02 AC015936.3 ACP2 ADCY9 ARHGAP42 ARID5B ARL14EP ARL17A ARL17B BHLHE41 BICC1 C17orf69 CARF CBWD1 CDK6 CES2 CHD6 CNNM2 CPEB2 CPEB4 CSNK1G3 CYB5D1 CYBRD1 DCAF16 DDX5 DNAJC18 DYDC2 ELP5 ERAP1 FHL3 FLJ33630 GLS GTF2B HM13 IBA57 KANSL1 KAT5 KIF18B LDB1 LFNG LOC441601 LRIG2 LRRC55 NELFCD NMT1 NOV NSF NSFP1 NUP160 PEX1 PHF21A PLEKHM2 PLN PRSS3 PSMB7 RERE RP11-166B2.1 RP11-981P6.1 RP13-514E23.2 RP4-635E18.7 RPS2 RPS6KL1 SEC31B SENP2 SGIP1 SIPA1 SLC5A11 SLC9A3R2 SMG6 SNX32 SOX6 ST5 STYX TCF7L1 TCP11 THAP3 TMBIM1 TMEM87B TRABD TRIOBP UBA7 UBE2E3 UGGT1 VGLL4 WNT2B ZCCHC10 ZNF318 ZNF827 ZNRF3
BMI 1.48 63 43 95.6 -0.20 8.7e-02 AC006547.14 AC091133.1 ACP2 ADCY3 ADCY9 AP001816.1 ARL14EP ARNTL ARVCF C2orf69 C4orf22 C6orf142 CARF CNNM2 CPEB4 DHX36 DNAJC3-AS1 ERAP1 FAM108C1 FIBP GALNT4 GFPT1 GRB14 HTR4 KDM2B LRIG1 MYBPC3 NADK NEK4 NUP160 OLA1 PEPD PLEKHM2 POC1B PPAP2B RGS19 ROGDI RP11-179B2.2 RP11-981P6.1 RP13-870H17.3 RSRC2 SENP2 SFXN2 SFXN3 SGSM3 SLC25A37 SLC2A4RG SLC35E2 SLC5A11 SLC9A3R2 SNF8 SNX11 SNX32 ST5 TCF7L2 TEAD3 THAP3 TRIM47 TRIM73 TRIM8 UBA7 UBE2Z UBN1
Height 1.77 185 156 346.7 -0.34 4.2e-07 AC010883.5 AC074212.6 AC091133.1 ACAP1 ACE ACP2 ADAM11 ADCY3 ADCY9 ADM ADO ADRB1 ANKS3 ARC ARHGAP42 ARID5B ARL14EP ARL17A ARL17B ATF1 ATXN1L AZI1 C11orf30 C17orf104 C17orf68 C1orf84 CCNT2 CCT6A CDK6 CENPW CERS5 CGREF1 CLIC4 COPB1 CRK CRLF3 CSNK1G3 CTD-2203K17.1 CYBRD1 CYTH1 DCAF16 DDX5 DHX36 DKFZp686O24166 DNAJC18 DPCD EDEM3 EFCAB13 EXD1 FBXW4 FER FES FGGY FHL3 FLJ33630 FURIN GAB1 GAPVD1 GCHFR GFER GFPT1 GLYR1 GOLGA1 GOPC GOSR2 GTF2B HADH HM13 INO80 ITSN1 KANK2 KANSL1 KCNG3 KIAA0753 KIF5B LIMA1 LRIG2 LSM11 LSP1 MAP6D1 MAPKAP1 MEA1 MED19 MED28 MMACHC MPP6 MRPL24 MXD4 MYBPC3 MYLPF NEK4 NFKBIA NMT1 NOC3L NOV NPR3 NSF NSFP1 NUDT16L1 NUP160 OAF OCIAD1 OIP5-AS1 PBX3 PCCB PEX1 PHF21A PIGV PLCD3 POLL POLN PPP2R2D PPP3R1 PPP6C PREX1 PSMD5-AS1 PTPN12 PUSL1 RABGAP1 RABL2A RASIP1 RERE RGS12 RHOC ROGDI RP11-1055B8.4 RP11-166B2.1 RP11-179B2.2 RP11-332H18.4 RP11-373D23.3 RP11-379F4.7 RP13-514E23.2 RP4-605O3.4 RP4-635E18.7 RP5-1029K10.2 RPL39P5 RPS6KL1 RSRC2 RTF1 RYK S1PR2 SAV1 SCRN2 SEC23IP SENP2 SENP3 SEPT12 SFXN2 SH2B3 SIPA1 SLC25A37 SLC4A7 SLC5A11 SLC9A3R2 SLFNL1 SMARCA4 SMG6 SMOC1 SNF8 SNX11 SNX32 SRD5A3 SRPK1 TCP11 TEX2 TMBIM1 TMEM170A TMEM180 TRIM73 TRIOBP TRPM7 UBE2Z UBN1 UBXN2A UGGT1 UPF3A UQCC1 WNT2B ZFP1 ZNF318 ZNF500 ZNF557 ZNF585B ZNF827 ZNF831
Waist Hip Ratio (WHR) 1.83 52 41 91.1 0.55 3.5e-06 ADAM1A ADCY3 ADM BHLHE41 C22orf31 CASC7 CFHR4 CPEB4 CTC-228N24.3 CTD-3032J10.3 DKFZp686O24166 DMXL1 FLJ33630 GABPB2 GAPVD1 GPAM GPR137 GRB14 HOXC8 ITGA9 KAT5 MAPKBP1 MEA1 MKRN2 MRAS MRVI1 NEK4 OPRL1 PCCB PCNX PDCL2 PEPD PLA2G4B PPP6C PTPN12 RASIP1 RGS19 RP11-156P1.3 RP11-332H18.4 RSRC2 SIPA1 SNX32 SRD5A3 SWAP70 TCF7L2 TMBIM1 TOM1L2 UQCC1 ZCCHC10 ZMYM4 ZNF318 ZNRF3
Smoking Status 1.49 14 8 17.8 -0.38 1.1e-01 ADAM1A ARL17B C17orf75 CADM2 GAPVD1 GOLGA1 MAPKAP1 PBX3 PDXDC2P PPP6C RERE SLC5A11 SMG6 UBE2E3
Allergy or Eczema 1.55 23 14 31.1 0.28 1.9e-01 ADAM1A C11orf1 C11orf30 CFHR4 EXD1 GCHFR INO80 KDM2B LIME1 OIP5-AS1 PLEKHM2 POLI PSMB7 RERE RP11-373D23.3 RP5-1029K10.2 RTF1 SLC15A2 SLC2A4RG SMAD3 TMBIM1 TMEM170A ZMYM4
Cardiovascular Disease 6.12 189 121 268.9 0.97 2.1e-147 AC006111.1 AC006547.13 AC006547.14 AC010883.5 AC091133.1 ACADVL ACE ACP2 ACTRT3 ADAM1A ADO ADRB1 ADRB2 AGT AGTRAP ARHGAP42 ARL14EP ARL17A ARNTL ARVCF ATP2B1 BRAP C10orf118 C11orf1 C22orf31 C4orf22 CACNB2 CDK6 CENPW CEP68 CERS5 CGREF1 CLCN6 CLIC4 CNNM2 CPEB4 CRK CRLF3 CSK CTC-228N24.3 CTD-3032J10.3 CTSZ CYB5D1 CYTH1 DCAF16 DKFZp686O24166 DMXL1 EFCAB13 ENPEP ERAP1 EXD1 FAM108C1 FBXO41 FCN3 FES FGF5 FMNL3 FURIN FUT11 GAB1 GCHFR GLTP GLYR1 GOPC GOSR2 GTF2B GUCY1A3 HELLS HIBADH HOXA10 HOXB9 HOXC8 HRCT1 HTR4 HTRA1 IFT172 INO80 IPO11 IRAK1BP1 ITGB3 ITGB5 KANK2 KDM2B LA16c-358B7.3 LFNG LIMA1 LOC441601 LSP1 MAPKAP1 MCF2L-AS1 MED21 MRAS MRPL35 MTHFR NAA25 NAT15 NEDD4L NELFCD NFKBIA NME6 NMT1 NOC3L NPPA NSF NSFP1 NSUN6 NUP160 OIP5-AS1 OLA1 OPRL1 PCCB PCNX PDXK PIGV PLA2G4B PLCB1 PLEKHM2 POC1B PPP3R1 PRDM8 RASIP1 RGS12 RGS19 RHOC RP11-1055B8.4 RP11-332H18.4 RP11-373D23.3 RP11-379F4.7 RP11-513M16.7 RP11-588K22.2 RP11-819C21.1 RP11-981P6.1 RP13-514E23.2 RP4-605O3.4 RP4-635E18.7 RP5-1029K10.2 RTF1 RYK SENP1 SENP3 SEPT12 SFXN2 SGIP1 SH2B3 SIDT2 SIPA1 SLC12A2 SLC2A4RG SLC4A7 SMARCA4 SNF8 SNX16 SNX32 SOX6 SPEN SPRY4 SRD5A3 SWAP70 TCF21 TEX2 TH1L THAP3 TMBIM1 TMEM116 TMEM170A TMEM26 TMEM87B TNNI2 TNNT3 TP53INP1 TRAFD1 TRIM47 TRIM59 TUBB1 UBE2E3 UBE2Z UPF3A VGLL4 WIPF1 WNT2B YES1 ZBTB46 ZCCHC10 ZNF100 ZNF318 ZNF443 ZNF557 ZNF831 ZNRF3
Hypothyroidism (self reported) 1.51 15 7 15.6 0.39 1.5e-01 ADAM1A ANKRD65 ARID5B BRAP FHL3 NAA25 PSMB7 PSMD5-AS1 PUSL1 RASIP1 RERE RP11-6N17.6 SH2B3 SLC25A37 UBE2E3
Respiratory disease 1.43 10 7 15.6 0.52 1.0e-01 AC074212.6 DDX5 HHEX OIP5-AS1 RERE RP5-1029K10.2 RTF1 SLC2A4RG SMAD3 TCP11
Type 2 Diabetes (T2D) (2018) 1.73 9 5 11.1 0.72 2.0e-02 DKFZp686O24166 GRB14 HHEX MAPKBP1 PLA2G4B SNX32 TCF7L2 UBA7 ZBTB46
Lung FEV1/FVC ratio 1.68 52 33 73.3 -0.24 7.8e-02 AC074212.6 ADCY3 ADM ADO AFAP1 ARHGAP42 ATP2B1 ATP8B3 C22orf31 CACNB2 CARF CASC7 CPEB4 CTC-228N24.3 CYB5D1 CYP46A1 DDX5 DHX36 DYDC2 FBXO38 FLJ33630 FTOP1 GFPT1 GOPC HAAO HELLS HOXC8 HOXD-AS1 HTR4 KCNG3 MAPKBP1 MMACHC MRVI1 NFKBIA NOV PLA2G4B PNMA1 RASIP1 RERE RP11-244F12.3 RP5-1029K10.2 S1PR2 SLC24A3 SMAD3 SNX11 TCP11 THAP3 TMEM170A TRIOBP ULK4 VGLL4 ZCCHC10
Lung FVC 1.43 55 32 71.1 -0.18 1.5e-01 ABLIM3 ACADVL ADAM11 ARID5B ARL17A ARL17B C17orf69 C8orf58 CFHR4 COMMD7 CRK CTC-228N24.3 DCAF16 DDHD2 EXD1 FLJ33630 FMNL3 GABPB2 GCHFR GFPT1 HM13 HOXA10 HOXC8 HTR4 INO80 KANSL1 NAT15 NDUFA2 NOV NSF NSFP1 OPRL1 PDXDC2P RGS19 RP11-1055B8.4 RP11-156P1.3 RP11-332H18.4 RP11-379F4.7 RP11-6N17.6 RTF1 SIDT2 SLC12A2 SLC2A4RG SNX31 SOX6 TCF21 TCP11 TRIOBP UBA7 UBXN2A UQCC1 WNT2B ZBTB46 ZCCHC10 ZNF500
Neuroticism 1.52 21 11 24.4 -0.31 1.4e-01 ADM ARL17A ARL17B ARNTL CADM2 CNNM2 ELP4 FES FIGN FURIN GOLGA1 KANSL1 MMAB NSF NSFP1 NUP160 PCCB PPP6C RERE RNF130 RPS6KL1
Chronotype (morning person) 1.09 8 2 4.4 0.38 3.6e-01 ACP2 BRAP C10orf26 HOXB3 MARCH10 NAA25 PSMB7 TMEM116
Hair Pigment 1.89 46 32 71.1 0.06 6.1e-01 AC006547.14 ACP2 ADM ANKRD65 ARL17A ARVCF ATP2B1 BHLHE41 BRAP C22orf31 C4orf22 CBWD1 CGREF1 COMMD7 FES FGF5 GALNT4 GOSR2 HM13 IFT172 KAT5 LRRC46 MC1R NDUFS4 OPRL1 PCNX PIGV POC1B RGS19 RP11-156P1.3 RP11-373D23.3 RP11-6N17.6 RP11-981P6.1 RP5-1087E8.3 SCRN2 SH2B3 SIDT2 SIPA1 SNX11 SNX32 SOX6 TOX3 UQCC1 WDPCP ZNF831 ZNRF3
Tanning 1.17 11 8 17.8 -0.26 4.5e-01 ADCY3 ADO CADM2 COMMD7 GABPB2 MC1R MYBPC3 RP5-1087E8.3 SH2B3 SNX11 UQCC1
Hand grip strength (left) 1.56 27 6 13.3 -0.04 8.4e-01 ADAM11 ADCY3 ARL17B C17orf104 DCAF16 FBXW4 FER GFER GOLGA1 MYBPC3 NMT1 NSF NUDT16L1 PLCD3 PPP3R1 RP11-379F4.7 RP11-6N17.6 RP1-257A7.5 SFXN2 SLC5A11 SLC9A3R2 SNX11 TCP11 TNNT3 TRIOBP UQCC1 ZNF500
Number of treatments/medications taken 2.07 11 5 11.1 0.88 3.8e-04 ACE ARHGAP42 CGREF1 DCAF16 FAM108C1 FBXO41 NUDT16L1 PPP2R2D SH2B3 UBA7 ZNF831
Average weekly spirits intake 1.18 1 0 0.0 0.00 1.0e+00 RASIP1
Sensitivity / hurt feelings 1.44 6 3 6.7 -0.79 1.9e-02 AC099850.1 ARL17B FES FURIN NSF SNF8
Hearing difficulty/problems: Yes 1.16 4 1 2.2 -0.58 4.2e-01 ABLIM3 FUT11 MMACHC ZNF318
Relative age of first facial hair 1.23 11 6 13.3 -0.49 1.2e-01 ARL17B C17orf69 C4orf22 CCNT2 CHD6 FGF5 MC1R NSF RP11-156P1.3 RP11-179B2.2 VGLL4
Ever had hysterectomy (womb removed) 1.06 1 0 0.0 0.00 1.0e+00 OBFC1
Systolic blood pressure, automated reading 7.74 236 140 311.1 0.99 1.6e-225 ABCA12 ABHD17C AC006111.1 AC006547.14 AC074212.6 AC099850.1 ACADVL ACP2 ACTRT3 ADCY3 ADM ADO ADRB1 ADRB2 AGT ANKRD65 ARHGAP42 ARID5B ARL14EP ARL17A ARL17B ARVCF ATP2B1 ATP8B3 AZI1 BICC1 BRAP C10orf26 C17orf69 C17orf75 C1orf84 C22orf31 C4orf22 CACNB2 CCNT2 CDK6 CEP68 CERS5 CLCN6 CNNM2 COL21A1 CPEB2 CPEB4 CRK CSK CTC-228N24.3 CYP46A1 CYTH1 DCAF16 DKFZp686O24166 DOCK6 DULLARD EDEM3 EIF2AK4 EML1 EXD1 FAM108C1 FBXO38 FBXO41 FER FES FGF5 FGGY FHL3 FIBP FIGN FMNL3 FOXJ3 FURIN FUT11 GCHFR GLTP GLYR1 GOPC GOSR2 GTF2B HDAC7 HDDC3 HELLS HOXA10 HOXB3 HOXB4 HOXB9 HOXC8 HOXD-AS1 HTR4 IGFBP3 INO80 IPO11 IRAK1BP1 ITGA9 ITGB3 ITGB5 JPH2 KANSL1 LFNG LIMA1 LIME1 LOC441601 LOC441869 LRIG2 LSP1 MAP1B MAP6D1 MAPK4 MAPKAP1 MARK2 MATN3 MCF2L-AS1 MED19 MED21 MEGF9 MMACHC MPP6 MTHFR NAA25 NADK NAT15 NEK4 NFKBIA NME6 NMT1 NOC3L NOV NPR3 NSF NSFP1 NSUN6 NUDT16L1 NUP160 OBFC1 OCIAD1 OIP5-AS1 OLA1 OLFML2A OPRL1 PAFAH1B1 PDCL2 PDXDC2P PEX1 PIGV PLA2G4B PLEKHH2 PLEKHJ1 PLEKHM2 PNPT1 POC1B PPAP2B PPP3R1 PPP6C PSMB7 PUSL1 RABL2A RBM23 RERE RGS19 RHOC RNPS1 RP11-1055B8.4 RP11-244F12.3 RP11-332H18.4 RP11-379F4.7 RP11-588K22.2 RP11-6N17.6 RP11-78O7.2 RP11-819C21.1 RP11-841O20.2 RP11-981P6.1 RP1-257A7.5 RP13-514E23.2 RP4-605O3.4 RP4-647C14.2 RP5-1029K10.2 RPS6KB1 RPS6KL1 S1PR2 SCRN2 SENP3 SERPINI1 SFXN2 SGIP1 SH2B3 SIPA1 SIRT1 SKAP2 SLC12A2 SLC16A1 SLC20A2 SLC2A4 SLC2A4RG SLC35E2 SLC4A7 SLC5A11 SLC9A3R2 SLFNL1 SMG6 SNX11 SNX24 SNX32 STYX SWAP70 TBC1D19 TCP11 TEAD3 TEX2 TMBIM1 TMEM170A TMEM87B TNNI2 TNNT3 TNS3 TOX3 TRAFD1 TRIM59 TRIM73 TRPM7 TRPV4 TSNARE1 UBA7 UBAP1 UBE2Z UBXN2A UFL1 UGT2B7 ULK4 UPF3A VGLL4 WNT2B YES1 ZBTB46 ZNF318 ZNF500 ZNF557 ZNF827 ZNF831 ZNRF3
Eye problems/disorders: Diabetes related eye disease 1.17 1 0 0.0 0.00 1.0e+00 TCF7L2
Angina 1.99 6 3 6.7 0.77 6.0e-03 FES FURIN OPRL1 RGS19 RP1-257A7.5 TCF21
Medication: Metformin 1.52 2 1 2.2 0.00 1.0e+00 HHEX TCF7L2
Diabetes (father) 1.31 2 1 2.2 0.00 1.0e+00 SNF8 TCF7L2
Diabetes (mother) 1.25 1 1 2.2 0.00 1.0e+00 TCF7L2
Impedance of leg (right) 2.05 66 45 100.0 0.44 4.0e-05 AC006547.14 AC091133.1 ADCY3 ADM ARC ARVCF ATF1 C17orf69 C2orf69 C4orf3 C8orf58 CASC7 CERS5 CNNM2 CSNK1G3 CTC-228N24.3 CTD-3032J10.3 CYBRD1 DDHD2 DKFZp686O24166 ELP4 FAM108C1 FER FES FIBP FLJ33630 FURIN GABPB2 GAPVD1 GOLGA1 HAGH HELLS HOXB3 HOXC8 HOXD-AS1 IGFBP3 JPH2 LIMA1 NADK NEK4 NNT NOC3L PAFAH1B1 PASK PLA2G4B PLCD3 PPAP2B PPP6C PRRC2B RNF130 RP11-179B2.2 RP4-605O3.4 RP5-1029K10.2 RPS6KB1 SCRN2 SENP1 SFXN2 SLC12A2 SLC35E2 SWAP70 TEAD3 TRIM73 TRIM8 UBA7 UQCC1 WNT2B
Leg fat-free mass (left) 1.84 66 40 88.9 -0.44 7.1e-05 AC006547.14 ADAM11 ADCY9 ARVCF C10orf118 C2orf69 CADM2 CDK6 CENPW CNNM2 CPEB4 CSNK1G3 CTC-228N24.3 CYBRD1 CYTH1 DCAF16 DHX36 DNAJC18 DNAJC3-AS1 FAM108C1 FHL3 FLJ33630 GAPVD1 GFER GLYR1 GOLGA1 HELLS HOXB3 KANSL1 LRRC46 NADK NFKBIA NMT1 NOV NPR3 NUDT16L1 PEX1 PLCD3 PPP3R1 PPP6C PRRC2B RP11-179B2.2 RP11-332H18.4 RP13-514E23.2 RSRC2 S1PR2 SENP2 SEPT12 SFXN2 SLC12A2 SLC25A37 SLC35E2 SLC5A11 SLC9A3R2 SNX11 SRPK1 TCP11 TEAD3 TRIM47 TRIM73 TRIM8 UBA7 UBN1 UPF3A UQCC1 ZNF500
Trunk fat percentage 1.62 41 23 51.1 -0.10 5.3e-01 ABHD17C ADCY3 ADM ARL17A ARL17B ARNTL DHX36 EDEM3 GFPT1 GRB14 HOXA10 HOXC8 HTR4 KANSL1 KIF5B MC1R MRAS MYBPC3 NSF NSFP1 PDCL2 PEPD POC1B POLL RERE RP11-981P6.1 RSRC2 SENP3 SFXN3 SLC25A37 SLC5A11 SLC9A3R2 SNX11 SRD5A3 SRPK1 THAP3 TRIM47 TRIM73 UBA7 UPF3A WNT2B
Hand grip strength (right) 1.56 18 11 24.4 -0.22 3.3e-01 ADAM11 ADCY3 CYBRD1 DCAF16 GFER GOLGA1 NMT1 PLCD3 PPP3R1 RHOC RP11-379F4.7 SFXN2 SLC5A11 SLC9A3R2 SLFNL1 TNNT3 UQCC1 WNT2B
Current tobacco smoking 1.43 4 2 4.4 -1.00 3.1e-06 GOLGA1 MAPKAP1 PBX3 PPP6C
Average weekly fortified wine intake 0.99 1 0 0.0 0.00 1.0e+00 SLC5A11
Maternal smoking around birth 1.21 1 1 2.2 0.00 1.0e+00 SLC5A11
Fed-up feelings 1.26 7 1 2.2 -0.07 8.8e-01 ARL17B ARNTL ELP5 NUP160 RPS6KL1 SH2B3 SLC5A11
Relative age voice broke 1.02 2 2 4.4 0.00 1.0e+00 ARL17B UQCC1
Taking other prescription medications 1.19 2 2 4.4 0.00 1.0e+00 SH2B3 UBA7
Age when periods started (menarche) 1.24 14 5 11.1 -0.60 1.8e-02 ARNTL AZI1 C1orf84 EXD1 FIBP INO80 LSP1 MEA1 NEK4 NFKBIA SNX32 ST5 TNNI2 TRIM73
Bilateral oophorectomy (both ovaries removed) 1.17 1 0 0.0 0.00 1.0e+00 OBFC1
Heel bone mineral density (BMD) T-score, automated (left) 1.32 15 8 17.8 0.42 1.0e-01 CDK6 CSNK1G3 CYB5D1 FHL3 KAT5 LRRC55 PHF21A RERE RP13-514E23.2 SIPA1 UBA7 UBE2E3 WNT2B ZNF827 ZNRF3
High blood pressure 6.14 153 91 202.2 0.98 3.2e-120 ABCA12 AC006111.1 AC091133.1 ACADVL ACE ACP2 ACTRT3 ADAM1A ADO ADRB1 ADRB2 AGT ANKS3 ARHGAP42 ARL17B ARNTL ATP2B1 BICC1 BRAP C10orf118 C11orf1 C22orf31 C4orf22 CACNB2 CASC7 CENPW CERS5 CLCN6 CNNM2 CSK CTD-3032J10.3 CTSZ CYB5D1 DCAF16 DKFZp686O24166 EBF2 ENPEP ERAP1 EXD1 FAM108C1 FCN3 FES FGF5 FURIN GAB1 GCHFR GLTP GLYR1 GOPC GOSR2 GTF2B HDAC7 HELLS HOXA10 HOXB9 HOXC8 HRCT1 HTR4 INO80 IPO11 IRAK1BP1 ITGB5 KDM2B LA16c-358B7.3 LFNG LIMA1 LIME1 LSP1 MAPKAP1 MARK2 MECR MED21 MRAS MTHFR NAA25 NAT15 NELFCD NME6 NMT1 NOC3L NPPA NPR3 NSUN6 NUDT16L1 NUP160 OIP5-AS1 OLA1 OPRL1 PDXK PIGV PLA2G4B PLCB1 PLEKHM2 PRDM8 PRKD3 PTPN12 RASIP1 RGS19 RHOC RP11-332H18.4 RP11-373D23.3 RP11-379F4.7 RP11-588K22.2 RP11-819C21.1 RP11-981P6.1 RP13-514E23.2 RP4-605O3.4 RP4-635E18.7 RSRC2 RTF1 RYK SENP1 SENP3 SFXN2 SGOL1 SH2B3 SIPA1 SKAP2 SLC17A6 SLC25A37 SLC2A4 SLC4A7 SLC5A11 SNF8 SNX16 SNX31 SOX6 SPEN ST5 SWAP70 TBC1D19 TH1L THAP3 TMEM116 TMEM26 TNNI2 TNNT3 TRAFD1 TRIM47 TRIM59 TUBB1 UBAP1 UBE2E3 UBE2Z UFL1 UPF3A VGLL4 WNT2B ZBTB46 ZNF318 ZNF443 ZNF831 ZNRF3
Hayfever, allergic rhinitis or eczema 1.42 17 9 20.0 0.46 6.5e-02 ADAM1A C11orf1 C11orf30 C17orf69 EXD1 GCHFR INO80 MEGF9 OIP5-AS1 PSMB7 PSMD5-AS1 RERE RP11-373D23.3 RTF1 SLC15A2 SLC2A4RG SMAD3
Supplements: Glucosamine 1.22 1 0 0.0 0.00 1.0e+00 ADO
Medication: Atenolol 2.79 5 2 4.4 0.97 1.8e-05 ARHGAP42 CLCN6 FES FURIN SH2B3
Medication: Levothyroxine sodium 1.47 9 5 11.1 0.81 8.4e-03 ADAM1A ARID5B BRAP NAA25 PUSL1 RP11-6N17.6 SH2B3 TMEM116 TRAFD1
Sitting height 1.61 89 56 124.4 -0.14 1.7e-01 AC074212.6 ADAM11 ADCY3 ADM ADRB1 APOLD1 ARL14EP ARL17A ARL17B ATF1 C10orf118 CDK6 CENPW CERS5 CSNK1G3 CYBRD1 DCAF16 DNAJC18 EXD1 FAM108C1 FBXW4 FHL3 GAPVD1 GLYR1 GOPC GOSR2 GTF2B HELLS HIBADH HM13 IGFBP3 KANSL1 LDB1 LIMA1 MAPKAP1 MED28 MMACHC MRPL24 MYBPC3 NDUFA2 NFKBIA NMT1 NOV NPR3 NSF NSFP1 NUDT16L1 NUP160 OIP5-AS1 PBX3 PEX1 PLCD3 PPP3R1 PPP6C PREX1 RASIP1 RGS12 RP11-1055B8.4 RP11-179B2.2 RP11-379F4.7 RP4-605O3.4 RP5-1029K10.2 RPL39P5 RSRC2 RTF1 S1PR2 SEPT12 SLC25A37 SLC4A7 SLC9A3R2 SLFNL1 SMOC1 SNF8 SRD5A3 SRPK1 TMBIM1 TMEM180 TNNT3 TRIOBP UBE2Z UBN1 UBXN2A UPF3A UQCC1 VGLL4 ZFP1 ZNF557 ZNF585B ZNF831
High blood pressure (mother) 3.22 17 5 11.1 0.94 7.3e-11 AGT ARHGAP42 CENPW CLCN6 CNNM2 FES FURIN HOXA10 HOXC8 KANK2 PIGV SENP1 SLC4A7 TMEM170A TNNT3 UBE2Z ZNF831
Body mass index (BMI) 1.37 34 21 46.7 -0.20 2.4e-01 AC006547.14 AC091133.1 ADCY3 ARNTL CARF CNNM2 DHX36 EDEM3 FIBP GALNT4 GRB14 HTR4 MYBPC3 NADK NEK4 OLA1 PEPD POC1B RP11-179B2.2 RP11-981P6.1 RSRC2 SFXN3 SLC35E2 SLC5A11 SLC9A3R2 SNF8 SNX32 ST5 TCF7L2 TEAD3 THAP3 TRIM73 TRIM8 UBA7
Impedance of leg (left) 2.06 64 44 97.8 0.48 8.4e-06 AC006547.14 AC091133.1 ADCY3 ADM ARC ARVCF ATF1 C2orf69 C4orf3 C8orf58 CASC7 CERS5 CNNM2 CSNK1G3 CTC-228N24.3 CTD-3032J10.3 CYBRD1 DDHD2 DKFZp686O24166 ELP4 FAM108C1 FES FIBP FLJ33630 FURIN GABPB2 GAPVD1 GOLGA1 HAGH HELLS HOXB3 HOXD-AS1 LIMA1 MC1R NADK NEK4 NMT1 NNT NOC3L PAFAH1B1 PASK PLA2G4B PLCD3 PPAP2B PPP6C PRRC2B RNF130 RP11-179B2.2 RP4-605O3.4 RP5-1029K10.2 RPS6KB1 SCRN2 SFXN2 SLC12A2 SLC35E2 SWAP70 TEAD3 TP53INP1 TRIM73 TRIM8 UBA7 ULK4 UQCC1 WNT2B
Leg predicted mass (left) 1.84 65 39 86.7 -0.43 1.1e-04 ADAM11 ADCY9 ARVCF C10orf118 C2orf69 CADM2 CDK6 CENPW CNNM2 CPEB4 CSNK1G3 CTC-228N24.3 CYBRD1 CYTH1 DCAF16 DHX36 DNAJC3-AS1 FAM108C1 FHL3 FLJ33630 GAPVD1 GFER GLYR1 GOLGA1 HELLS HOXB3 KANSL1 LRRC46 NADK NFKBIA NMT1 NOV NPR3 NUDT16L1 PEX1 PLCD3 PPP3R1 PPP6C PRRC2B RP11-179B2.2 RP11-332H18.4 RP13-514E23.2 RSRC2 S1PR2 SENP2 SEPT12 SFXN2 SLC12A2 SLC25A37 SLC35E2 SLC5A11 SLC9A3R2 SMOC1 SNX11 SRPK1 TCP11 TEAD3 TRIM47 TRIM73 TRIM8 UBA7 UBN1 UPF3A UQCC1 ZNF500
Trunk fat mass 1.52 45 26 57.8 -0.11 4.2e-01 ABHD17C ADCY3 ARL17A ARL17B ARNTL CDK6 CNNM2 DHX36 ERAP1 GFPT1 GRB14 HOXA10 HTR4 KANSL1 MRAS MYBPC3 NSF NSFP1 NUDT16L1 OCIAD1 OLA1 PEPD POC1B RERE RP11-179B2.2 RP11-981P6.1 RSRC2 SEPT12 SFXN3 SLC25A37 SLC5A11 SLC9A3R2 SNX11 SNX32 SRD5A3 SRPK1 ST5 THAP3 TRIM47 TRIM73 UBA7 UBN1 UPF3A UQCC1 WNT2B
Waist circumference 1.37 33 18 40.0 -0.14 3.9e-01 ACADVL ADCY3 ADCY9 ARNTL CARF CDK6 DHX36 DULLARD FAM108C1 FIBP HOXC8 HTR4 MYBPC3 NADK OLA1 POC1B RP11-179B2.2 RP11-981P6.1 SEPT12 SIPA1 SLC25A37 SLC2A4RG SLC35E2 SLC5A11 SLC9A3R2 SNX11 SNX32 SRPK1 ST5 TEAD3 THAP3 TRIM73 UBA7
Number of incorrect matches in round 1.22 2 1 2.2 0.00 1.0e+00 FURIN PREX1
Past tobacco smoking 1.29 7 1 2.2 0.21 6.5e-01 ADAM1A C17orf68 CADM2 GAPVD1 PDXDC2P PPP6C SH2B3
Alcohol usually taken with meals 1.34 2 0 0.0 0.00 1.0e+00 C1orf84 COMMD7
Nervous feelings 1.39 9 3 6.7 -0.06 8.8e-01 ARL17B CADM2 CNNM2 NEK4 NSF NUP160 PCCB PPP6C SMG6
Frequency of tenseness / restlessness in last 2 weeks 1.18 3 0 0.0 0.00 1.0e+00 ARL17B MMAB NSF
Hearing difficulty/problems with background noise 1.23 2 1 2.2 0.00 1.0e+00 CSK ZNF318
Hair/balding pattern: Pattern 2 1.38 6 4 8.9 -0.82 4.3e-02 ARL17B C4orf22 COMMD7 CPEB2 FGF5 PRDM8
Had menopause 1.16 2 0 0.0 0.00 1.0e+00 EXD1 INO80
Forced vital capacity (FVC) 1.76 41 28 62.2 -0.28 7.3e-02 ACP2 ADAM11 ADCY3 ARL17A ARL17B C17orf69 CDK6 CENPW CTC-228N24.3 CYBRD1 DCAF16 FER FHL3 FLJ33630 FMNL3 GABPB2 HTR4 KANSL1 MYBPC3 NOV NSF NSFP1 NUDT16L1 PPP3R1 PREX1 RGS12 RHOC RP11-1055B8.4 RP11-156P1.3 RP11-179B2.2 RP11-379F4.7 RSRC2 SLC12A2 SLC2A4RG SLFNL1 TCP11 TMBIM1 TMEM180 UBE2Z UPF3A ZNF500
Heel bone mineral density (BMD) T-score, automated (right) 1.35 12 8 17.8 0.24 3.9e-01 ACP2 CDK6 CYB5D1 FHL3 KAT5 LRRC55 RERE RP13-514E23.2 SIPA1 UBA7 WNT2B ZNRF3
Qualifications: None of the above 1.30 9 4 8.9 0.69 4.0e-02 ATXN1L IRAK1BP1 KANSL1 MPP6 NUDT16L1 RSRC2 SLC5A11 UBA7 UBE2Z
Mouth/teeth dental problems 1.07 1 0 0.0 0.00 1.0e+00 RASIP1
Heart attack 1.80 3 2 4.4 -0.81 2.9e-02 FES RP1-257A7.5 TCF21
Allergy 1.47 19 9 20.0 -0.28 2.4e-01 C11orf1 C11orf30 C17orf69 CLIC4 EXD1 FES HDAC7 INO80 LIME1 OIP5-AS1 PSMB7 RERE RP11-373D23.3 RP5-1029K10.2 RTF1 SLC15A2 SLC2A4RG SMAD3 TMBIM1
Diabetes (self-reported) 1.51 5 4 8.9 0.56 3.2e-01 DKFZp686O24166 FLJ33630 HHEX TCF7L2 UBA7
Hayfever/allergic rhinitis (self-reported) 1.27 2 0 0.0 0.00 1.0e+00 C11orf30 SMAD3
Medication: Ramipril 2.31 2 2 4.4 0.00 1.0e+00 ARHGAP42 CSK
Medication: Simvastatin 2.16 6 3 6.7 0.79 3.8e-03 FES OPRL1 PIGV RASIP1 RGS19 ZNF831
Fluid intelligence score 1.09 5 3 6.7 -0.30 6.2e-01 ATXN1L DCAF16 DKFZp686O24166 FBXO41 UBA7
Illnesses of siblings 1.97 3 0 0.0 -0.97 2.8e-02 FES SH2B3 SLC5A11
Neuroticism score 1.35 10 4 8.9 -0.26 4.3e-01 ADM ARL17B ARNTL ELP4 GOLGA1 NSF NUP160 PCCB PPP6C RERE
Weight 1.53 59 31 68.9 -0.34 3.5e-03 ADCY9 ATXN1L C10orf118 C2orf69 CDK6 CNNM2 CSNK1G3 CYBRD1 CYTH1 DCAF16 DHX36 ERAP1 FAM108C1 FIBP GAPVD1 GFER GFPT1 GLYR1 HOXB3 HTR4 KANSL1 LRRC46 NADK NFKBIA NUDT16L1 OCIAD1 OLA1 PEPD PEX1 POC1B POLN ROGDI RP11-179B2.2 RP11-332H18.4 RP11-981P6.1 RSRC2 SENP2 SEPT12 SFXN3 SLC25A37 SLC2A4RG SLC35E2 SLC5A11 SLC9A3R2 SNX11 SNX32 SRPK1 ST5 TCF7L2 TCP11 TEAD3 TRIM73 TRIM8 UBA7 UBN1 UPF3A UQCC1 WNT2B ZNF500
Impedance of arm (right) 1.67 66 40 88.9 0.25 2.7e-02 AC006547.14 ADM ARL17A ARL17B ARVCF BAHD1 C17orf69 C22orf31 CADM2 CERS5 CTD-3032J10.3 CTSO CYBRD1 DKFZp686O24166 ELP4 FER FIBP GAPVD1 GFPT1 GRB14 HELLS HOXA10 HOXB3 HOXC8 HOXD-AS1 KANSL1 KCNG3 LDB1 LIME1 LSP1 NADK NDUFS4 NEK4 NNT NOC3L NSF NSFP1 OPRL1 PAFAH1B1 PASK PEPD PPP3R1 PPP6C PRRC2B PSMB7 RGS19 RP11-156P1.3 RP11-179B2.2 RP11-373D23.3 RP4-605O3.4 RP5-1029K10.2 RPS6KB1 RYK SCRN2 SENP1 SENP3 SLC35E2 SLC4A7 SLC9A3R2 SNX16 SNX32 TEAD3 TRIM73 TRIM8 UBA7 WNT2B
Arm fat percentage (right) 1.56 44 20 44.4 0.12 4.2e-01 ABHD17C AC091133.1 ACADVL ACP2 ADCY3 ADM AP001816.1 ARL17A ARNTL C6orf142 DCAF16 DULLARD EDEM3 EXD1 GFPT1 GRB14 HOXA10 HTR4 KANSL1 MPP6 MYBPC3 NOV NSF NUP160 OIP5-AS1 OLA1 PEPD POC1B POLL RERE RP11-981P6.1 RSRC2 SENP3 SFXN3 SLC25A37 SLC5A11 SNF8 SNX32 ST5 TCF7L2 THAP3 TRIM47 TRIM73 UBA7
Trunk fat-free mass 1.95 78 56 124.4 -0.48 8.9e-07 ADAM11 ADCY3 ADCY9 ADM ARVCF ATXN1L C10orf118 C17orf69 C2orf69 CADM2 CDK6 CENPW CGREF1 CNNM2 CSNK1G3 CTC-228N24.3 CYBRD1 CYTH1 DCAF16 DHX36 DNAJC18 FAM108C1 FBXW4 FHL3 FLJ33630 GAPVD1 GFER GLYR1 GOLGA1 HELLS HOXB3 HOXD-AS1 KCNG3 MED28 NADK NFKBIA NMT1 NOV NPR3 NUDT16L1 OIP5-AS1 PEX1 PLCD3 PPP3R1 PPP6C PRRC2B RP11-179B2.2 RP11-332H18.4 RP11-373D23.3 RP11-78O7.2 RP13-514E23.2 RPL39P5 RPS6KL1 RSRC2 S1PR2 SENP2 SENP3 SEPT12 SFXN2 SH2B3 SLC25A37 SLC35E2 SLC4A7 SLC5A11 SLC9A3R2 SLFNL1 SMOC1 SNX11 SRPK1 TCP11 TEAD3 TMBIM1 TNS1 TRIM8 UBA7 UBE2Z UBN1 UQCC1
Hip circumference 1.58 46 27 60.0 -0.45 9.2e-04 ACADVL ADCY3 ANKS3 CDK6 CLCN6 CNNM2 CPEB4 CYBRD1 DHX36 ERAP1 FAM108C1 GAPVD1 GPR137 GRB14 HTR4 MRAS MYBPC3 NADK NFKBIA NPPA OLA1 PDCL2 PEPD RASIP1 RGS19 RP11-179B2.2 RP11-981P6.1 RSRC2 SEPT12 SFXN3 SH2B3 SLC25A37 SLC2A4RG SLC9A3R2 SNX11 SRPK1 ST5 TCF7L2 TEAD3 TRIM47 TRIM73 TRIM8 UBA7 UBN1 UPF3A UQCC1
Alcohol intake versus 10 years previously 1.21 3 1 2.2 0.00 1.0e+00 EDEM3 RASIP1 UBA7
Father's age at death 1.55 2 2 4.4 -1.00 2.7e-04 FES SH2B3
Worrier / anxious feelings 1.36 7 3 6.7 0.05 9.2e-01 ARNTL CADM2 CNNM2 NEK4 NSF PCCB TEAD3
Frequency of tiredness / lethargy in last 2 weeks 1.20 3 1 2.2 0.00 1.0e+00 MMAB SNF8 UBE2Z
Falls in the last year 1.22 1 0 0.0 0.00 1.0e+00 CASC7
Hair/balding pattern: Pattern 3 1.36 6 5 11.1 0.79 6.0e-02 ARL17B C17orf69 C4orf22 FGF5 NSF PRDM8
Forced expiratory volume in 1-second (FEV1) 1.74 31 19 42.2 -0.18 3.2e-01 ADCY3 ADO ARHGAP42 ARL17A ARL17B CDK6 CYBRD1 DCAF16 FBXO38 FER FHL3 GOLGA1 HTR4 KANSL1 NFKBIA NSF NSFP1 NUDT16L1 PREX1 RGS12 RHOC RP11-1055B8.4 RP11-156P1.3 RP11-179B2.2 RP11-379F4.7 SLC2A4RG TCP11 TMEM180 UPF3A ZCCHC10 ZNF500
Pulse rate 1.31 4 3 6.7 0.34 6.6e-01 MAPKAP1 NAA16 RBM23 TCF21
Qualifications: A levels/AS levels or equivalent 1.19 4 2 4.4 -0.94 6.3e-02 DCAF16 FBXO41 MPP6 UBA7
Mouth/teeth dental problems: Dentures 1.26 4 1 2.2 0.38 6.2e-01 CBX1 HOXB9 RASIP1 RPS6KB1
Asthma 1.43 10 3 6.7 0.61 5.9e-02 AC074212.6 HHEX HTR4 OIP5-AS1 RERE RP5-1029K10.2 RTF1 SLC2A4RG SMAD3 TCP11
Medication: Ibuprofen (e.g. Nurofen) 1.31 1 1 2.2 0.00 1.0e+00 RP1-257A7.5
Medication: Cholesterol lowering 2.07 6 3 6.7 0.80 3.0e-04 ARHGAP42 FES OPRL1 RASIP1 RGS19 THAP3
Lung cancer (father) 1.21 1 0 0.0 0.00 1.0e+00 RAD52
Illnesses of mother 2.19 3 1 2.2 -0.89 7.7e-03 FES SLC7A1 UBE2Z
Forced expiratory volume in 1-second (FEV1), Best measure 1.68 29 14 31.1 -0.17 3.7e-01 ADAM11 ADCY3 ADO ARL17A ARL17B CDK6 CYBRD1 DCAF16 FBXO38 FER FHL3 FMNL3 GABPB2 HTR4 KANSL1 NSF NSFP1 NUDT16L1 PREX1 RGS12 RP11-1055B8.4 RP11-156P1.3 RP11-179B2.2 RP11-379F4.7 TCP11 TMEM180 UPF3A ZCCHC10 ZNF500
Pulse wave Arterial Stiffness index 1.34 1 1 2.2 0.00 1.0e+00 ADAM1A
Impedance of arm (left) 1.63 59 36 80.0 0.23 5.6e-02 AC006547.14 ADM ARL17A ARL17B ARVCF C17orf69 C22orf31 CADM2 CERS5 CTD-3032J10.3 CTSO DKFZp686O24166 ELP4 FAM108C1 FER FIBP GAPVD1 GFPT1 GRB14 HELLS HOXB3 HOXC8 HOXD-AS1 KANSL1 KCNG3 KIF5B LDB1 LIME1 LSP1 MC1R NADK NDUFS4 NEK4 NOC3L NSF NSFP1 OPRL1 PASK PLCD3 PRRC2B PSMB7 RGS19 RP11-156P1.3 RP11-179B2.2 RP11-373D23.3 RP4-605O3.4 RP5-1029K10.2 RYK SCRN2 SENP3 SH2B3 SLC35E2 SLC9A3R2 SNX32 TEAD3 TNNT3 TRIM73 TRIM8 UBA7
Arm fat mass (right) 1.46 38 21 46.7 -0.13 4.0e-01 ABHD17C AC091133.1 ADCY3 ARL17A ARNTL CDK6 CNNM2 DHX36 ERAP1 FIBP GFPT1 GRB14 HTR4 KANSL1 MYBPC3 NADK OLA1 PEPD POC1B RP11-179B2.2 RP11-981P6.1 RSRC2 SFXN3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 SRPK1 ST5 TCF7L2 TEAD3 THAP3 TRIM47 TRIM73 TRIM8 UBA7 UBN1 UQCC1
Trunk predicted mass 1.95 76 56 124.4 -0.48 1.1e-06 ADAM11 ADCY3 ADCY9 ADM ATXN1L C10orf118 C17orf69 CADM2 CDK6 CENPW CGREF1 CNNM2 CSNK1G3 CTC-228N24.3 CYBRD1 CYTH1 DCAF16 DHX36 DNAJC18 FAM108C1 FBXW4 FHL3 FLJ33630 GAPVD1 GFER GLYR1 GOLGA1 HELLS HOXB3 HOXD-AS1 KCNG3 MED28 NADK NFKBIA NMT1 NOV NPR3 NUDT16L1 OIP5-AS1 PEX1 PLCD3 PPP3R1 PPP6C PRRC2B RP11-179B2.2 RP11-332H18.4 RP11-373D23.3 RP11-78O7.2 RP13-514E23.2 RPL39P5 RPS6KL1 RSRC2 S1PR2 SENP2 SENP3 SEPT12 SFXN2 SH2B3 SLC25A37 SLC35E2 SLC4A7 SLC5A11 SLC9A3R2 SLFNL1 SMOC1 SNX11 SRPK1 TCP11 TEAD3 TMBIM1 TNS1 TRIM8 UBA7 UBE2Z UBN1 UQCC1
Standing height 1.72 122 91 202.2 -0.31 2.1e-04 AC074212.6 AC091133.1 ACP2 ADAM11 ADCY3 ADCY9 ADM ADRB1 ANKS3 APOLD1 ARC ARL14EP ARL17A ARL17B ATF1 ATXN1L AZI1 C17orf68 CCT6A CDK6 CENPW CERS5 COPB1 CSNK1G3 CYBRD1 CYTH1 DCAF16 DKFZp686O24166 DNAJC18 EDEM3 EXD1 FER FHL3 GAB1 GAPVD1 GCHFR GFER GFPT1 GLYR1 GOPC GTF2B INO80 ITSN1 KANSL1 KIF5B LIMA1 MAPKAP1 MEA1 MED28 MMACHC MPP6 MYBPC3 MYLPF NEK4 NFKBIA NMT1 NOV NPR3 NSF NSFP1 NUDT16L1 NUP160 OAF OCIAD1 OIP5-AS1 PBX3 PCCB PEX1 PHF21A PIGV PLCD3 POLL PPP3R1 PREX1 PSMD5-AS1 RABGAP1 RASIP1 RGS12 RHOC RP11-1055B8.4 RP11-179B2.2 RP11-332H18.4 RP11-379F4.7 RP13-514E23.2 RP4-605O3.4 RP4-635E18.7 RP5-1029K10.2 RPL39P5 RPS6KL1 RSRC2 RTF1 RYK S1PR2 SEC23IP SENP2 SEPT12 SERPINI1 SH2B3 SIPA1 SLC25A37 SLC5A11 SLC9A3R2 SLFNL1 SMARCA4 SMOC1 SNF8 SNX11 SRPK1 TCP11 TMBIM1 TMEM170A TMEM180 UBE2Z UBN1 UPF3A UQCC1 WNT2B ZNF318 ZNF500 ZNF557 ZNF585B ZNF831
Exposure to tobacco smoke at home 1.15 1 0 0.0 0.00 1.0e+00 UBA7
Breastfed as a baby 1.33 4 1 2.2 -0.99 1.0e-03 ANKRD65 LOC441869 PUSL1 SLC35E2
Tense / 'highly strung' 1.22 2 1 2.2 0.00 1.0e+00 CADM2 RERE
Seen doctor (GP) for nerves, anxiety, tension or depression 1.21 1 0 0.0 0.00 1.0e+00 SGIP1
Hair/balding pattern: Pattern 4 1.68 17 11 24.4 0.44 6.6e-02 ARL17B C17orf69 C4orf22 CBWD1 CENPW CERS5 CHD6 CLIC4 FGF5 KANSL1 LGR4 LIMA1 NSF PRDM8 RP11-156P1.3 RP4-605O3.4 SMG6
Birth weight of first child 2.24 14 5 11.1 -0.92 3.6e-08 ACADVL ANKRD65 CLCN6 DCAF16 FES FURIN GTF2B HDDC3 NPPA OPRL1 PREX1 RP11-841O20.2 SH2B3 TMEM170A
Peak expiratory flow (PEF) 1.57 16 9 20.0 -0.32 2.0e-01 ABCA12 ACADVL ANKRD65 ARL17B DCAF16 FBXO38 HTR4 NSF PUSL1 RASIP1 SLC2A4 SLC9A3R2 TCF21 TCP11 TMEM170A UQCC1
Qualifications: O levels/GCSEs or equivalent 1.38 3 1 2.2 0.00 1.0e+00 NUDT16L1 RPS6KB1 ZNF500
Blood clot in the leg (DVT) 1.28 1 1 2.2 0.00 1.0e+00 ATP1B1
Medication: Paracetamol 1.36 4 2 4.4 0.41 5.9e-01 ARL17B CGREF1 RP1-257A7.5 UFL1
Headache pain in last month 1.52 6 4 8.9 -0.09 8.6e-01 ARL17B MED19 RP1-257A7.5 SLC24A3 TMEM170A UFL1
Medication for cholesterol, blood pressure or diabetes 3.50 17 12 26.7 -0.93 3.2e-12 ACE ARHGAP42 ATP2B1 CLCN6 CSK FES LFNG OPRL1 PDXK RGS19 RHOC SH2B3 SLC4A7 TCF21 THAP3 UPF3A ZNF831
Gout (self-reported) 1.14 3 1 2.2 0.00 1.0e+00 CGREF1 SH2B3 SIPA1
Hypothyroidism/myxoedema (self-reported) 1.41 7 4 8.9 0.72 6.9e-02 ADAM1A BRAP NAA25 PUSL1 RP11-6N17.6 SH2B3 SRPK1
Medication: Amlodipine 3.36 14 10 22.2 0.90 5.5e-08 ARHGAP42 CLCN6 FAM108C1 FES GLYR1 KDM2B LSP1 RHOC RP4-635E18.7 SENP3 SLC4A7 TNNT3 WNT2B ZNF318
Medication: Ventolin 100micrograms inhaler 1.15 1 0 0.0 0.00 1.0e+00 SMAD3
Birth weight 2.34 24 16 35.6 -0.29 1.4e-01 ACADVL ACAP1 ADAM1A ADCY9 ADRB1 BRAP C10orf26 C11orf1 CDK6 CNNM2 DCAF16 DULLARD ELP5 FES FURIN HHEX HTRA1 PREX1 PSMD5-AS1 RABGAP1 S1PR2 SH2B3 SLC2A4 ZNRF3
High blood pressure (siblings) 2.60 10 2 4.4 0.98 2.5e-09 ACP2 ADO ARHGAP42 CLCN6 FES JPH2 MTHFR SGIP1 SH2B3 SLC4A7
Forced vital capacity (FVC), Best measure 1.68 40 28 62.2 -0.31 4.3e-02 ACP2 ADAM11 ADCY3 ANKS3 ARL17A ARL17B CDK6 CENPW CYBRD1 DCAF16 FER FHL3 FLJ33630 FMNL3 GABPB2 HTR4 KANSL1 MYBPC3 NOV NSF NSFP1 NUDT16L1 PPP3R1 PREX1 RGS12 RHOC RP11-1055B8.4 RP11-156P1.3 RP11-179B2.2 RP11-379F4.7 RSRC2 SLC12A2 SLC2A4RG SLFNL1 TCP11 TMBIM1 TMEM180 UBE2Z UPF3A ZNF500
Body fat percentage 1.63 47 24 53.3 0.02 8.9e-01 ABHD17C AC091133.1 ADCY3 ADM ARL17A ARL17B ARNTL CHD6 CTC-228N24.3 DHX36 EDEM3 ERAP1 FLJ33630 GFPT1 GRB14 HELLS HOXA10 HOXC8 HTR4 KANSL1 MC1R MPP6 MYBPC3 NOV NSF OIP5-AS1 PDCL2 PEPD POC1B POLL RERE RP11-981P6.1 RSRC2 SENP3 SFXN3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 SRD5A3 SRPK1 TCF7L2 THAP3 TRIM47 TRIM73 UBA7 WNT2B
Leg fat percentage (right) 1.68 40 20 44.4 0.30 5.8e-02 ABHD17C ADCY3 ADM ARNTL CARF CRK CTC-228N24.3 DCAF16 EDEM3 ERAP1 EXD1 FIBP FLJ33630 GRB14 GTF2B HELLS HTR4 MPP6 MYBPC3 NMT1 NOV OIP5-AS1 OLA1 PEPD RERE RP11-981P6.1 RSRC2 SFXN3 SLC12A2 SLC2A4RG SLC5A11 SLC9A3R2 SNX32 ST5 TCF7L2 THAP3 TRIM73 UBA7 UQCC1 WNT2B
Arm fat-free mass (right) 1.81 70 41 91.1 -0.43 6.7e-05 AC006547.14 ADAM11 ADCY9 ADM ARVCF ATXN1L C10orf118 CADM2 CDK6 CENPW CGREF1 CNNM2 CSNK1G3 CYBRD1 CYTH1 DCAF16 DHX36 DNAJC18 DNAJC3-AS1 FAM108C1 FBXW4 FHL3 FIBP GAPVD1 GFER GLYR1 GOLGA1 HELLS HOXB3 KCNG3 LIME1 MED28 NADK NFKBIA NMT1 NOV PEX1 PLCD3 PPP3R1 PPP6C PRRC2B PSMB7 RASIP1 RP11-179B2.2 RP11-332H18.4 RP11-373D23.3 RP13-514E23.2 RSRC2 S1PR2 SENP3 SEPT12 SFXN2 SH2B3 SLC25A37 SLC2A4RG SLC35E2 SLC5A11 SLC9A3R2 SLFNL1 SNX32 SRPK1 TCP11 TEAD3 TMBIM1 TNS1 TRIM8 UBA7 UBE2Z UBN1 UQCC1
Comparative body size at age 10 1.49 16 10 22.2 -0.68 2.0e-03 ADCY3 ADCY9 CADM2 CERS5 LIMA1 MYBPC3 NADK NME6 RP4-605O3.4 SIPA1 SLC35E2 SMG6 TEAD3 THAP3 VGLL4 WNT2B
Worry too long after embarrassment 1.43 5 3 6.7 -0.97 1.5e-05 ARNTL GAPVD1 PCCB PPP6C RGS12
Wheeze or whistling in the chest in last year 1.18 4 4 8.9 -0.06 9.4e-01 C11orf1 SLC2A4RG SMAD3 UBA7
Number of children fathered 1.10 1 0 0.0 0.00 1.0e+00 CADM2
Age at first live birth 1.19 2 1 2.2 0.00 1.0e+00 DCAF16 UBA7
Pulse wave peak to peak time 1.34 1 1 2.2 0.00 1.0e+00 ADAM1A
Shortness of breath walking on level ground 1.16 1 0 0.0 0.00 1.0e+00 SGIP1
Qualifications: College or University degree 1.18 15 6 13.3 -0.68 5.7e-03 ARL17B DCAF16 FBXO41 GTF2B KANSL1 KIF5B MMACHC MPP6 PPP2R2D RGS12 RP11-1055B8.4 RP11-166B2.1 SIRT1 SLC5A11 UBA7
Medication for pain relief, constipation, heartburn 1.34 5 3 6.7 -0.99 9.3e-04 C17orf68 CGREF1 FAM108C1 RP1-257A7.5 UFL1
Neck or shoulder pain in last month 1.14 1 1 2.2 0.00 1.0e+00 ATXN1L
Medication: Blood pressure 4.34 42 23 51.1 0.97 2.4e-30 AC091133.1 ACADVL ACE ACP2 ADAM1A ADRB1 ARHGAP42 ATP2B1 BICC1 C4orf22 CLCN6 CSK CYB5D1 FAM108C1 FBXO41 FES FGF5 FURIN HOXA10 KDM2B LFNG LSP1 NME6 NOC3L NUP160 PDXK PLCB1 RGS19 RHOC RP11-819C21.1 RP4-635E18.7 SENP1 SH2B3 SLC2A4 SLC4A7 TCF21 THAP3 TNNI2 TNNT3 UPF3A WNT2B ZNF831
Angina (self-reported) 1.95 6 2 4.4 0.77 5.3e-03 FES FURIN OPRL1 RGS19 RP1-257A7.5 TCF21
Migraine (self-reported) 1.47 4 1 2.2 0.31 6.1e-01 RP1-257A7.5 SFXN2 SLC24A3 UFL1
Medication: Ibuprofen 1.28 2 0 0.0 0.00 1.0e+00 RP1-257A7.5 UBE2E3
Medication: Allopurinol 1.14 1 0 0.0 0.00 1.0e+00 CGREF1
Mean time to correctly identify matches 1.53 9 8 17.8 -0.16 6.5e-01 ARL17A BRAP KANSL1 NAA25 NSF NSFP1 OLA1 PHF21A SH2B3
Whole body fat mass 1.48 43 24 53.3 -0.10 4.9e-01 ABHD17C ADCY3 ARL17A ARL17B ARNTL CDK6 CNNM2 DHX36 ERAP1 FIBP GFPT1 GRB14 HTR4 KANSL1 MRAS MYBPC3 OCIAD1 OLA1 PEPD POC1B RERE RP11-179B2.2 RP11-981P6.1 RSRC2 SFXN3 SLC25A37 SLC2A4RG SLC5A11 SLC9A3R2 SNX11 SNX32 SRPK1 ST5 TCF7L2 THAP3 TRIM47 TRIM73 TRIM8 UBA7 UBN1 UPF3A UQCC1 WNT2B
Leg fat mass (right) 1.47 35 22 48.9 -0.14 3.8e-01 ADCY3 ARNTL CARF CDK6 DHX36 ERAP1 FIBP GRB14 HTR4 MPP6 MYBPC3 NADK OLA1 PEPD POC1B RERE RP11-179B2.2 RP11-981P6.1 RSRC2 SFXN3 SLC25A37 SLC2A4RG SLC5A11 SLC9A3R2 SNX32 SRPK1 ST5 TCF7L2 TEAD3 THAP3 TRIM73 TRIM8 UBA7 UBN1 WNT2B
Arm predicted mass (right) 1.83 67 41 91.1 -0.42 1.1e-04 AC006547.14 ADAM11 ADCY9 ADM ARVCF ATXN1L C10orf118 CADM2 CDK6 CENPW CNNM2 CSNK1G3 CYBRD1 CYTH1 DCAF16 DHX36 DNAJC18 DNAJC3-AS1 FAM108C1 FBXW4 FHL3 GAPVD1 GFER GLYR1 GOLGA1 HELLS HOXB3 LIME1 MED28 NADK NFKBIA NMT1 NOV OIP5-AS1 PEX1 PLCD3 PPP3R1 PPP6C PRRC2B PSMB7 RASIP1 RP11-179B2.2 RP11-332H18.4 RP11-373D23.3 RSRC2 S1PR2 SENP3 SEPT12 SFXN2 SH2B3 SLC25A37 SLC2A4RG SLC35E2 SLC5A11 SLC9A3R2 SLFNL1 SNX32 SRPK1 TCP11 TEAD3 TMBIM1 TNS1 TRIM8 UBA7 UBE2Z UBN1 UQCC1
Pulse rate, automated reading 1.39 20 10 22.2 0.28 2.1e-01 ACP2 ANKS3 C11orf1 C6orf142 CES2 CSNK1G3 DNAJC18 HIBCH LDB1 MAPKAP1 NAA16 NUDT16L1 PBX3 PHACTR4 RBM23 SEC31B SENP2 TCF21 TMEM26 UBA7
Alcohol intake frequency. 1.06 9 3 6.7 0.19 6.2e-01 ARL17B CADM2 CGREF1 MYBPC3 RASIP1 RGS12 RP1-257A7.5 RPS6KB1 UBA7
Comparative height size at age 10 1.65 68 42 93.3 -0.32 5.3e-03 AC010883.5 ADAM11 ADCY3 ADCY9 ARL17A ATXN1L C1orf84 CDK6 CENPW CYBRD1 CYTH1 DCAF16 DKFZp686O24166 DNAJC18 FAM108C1 FBXW4 FER GFER GFPT1 GLYR1 GTF2B HADH HOXB3 IGFBP3 KANSL1 KIF5B LSM11 MED28 MMACHC MYBPC3 NEK4 NFKBIA NOV NPR3 NSF NUDT16L1 OCIAD1 PCCB PIGV PLCD3 PREX1 RASIP1 RGS12 RP11-179B2.2 RP11-332H18.4 RP4-635E18.7 RSRC2 S1PR2 SENP2 SEPT12 SFXN2 SH2B3 SLC25A37 SLC9A3R2 SLFNL1 SMOC1 SRPK1 TCP11 TMBIM1 TMEM170A UBE2Z UPF3A UQCC1 WNT2B ZFP1 ZNF500 ZNF557 ZNF585B
Suffer from 'nerves' 1.28 5 3 6.7 0.96 1.0e-02 CADM2 MYBPC3 NUP160 RNF130 SMG6
Overall health rating 1.43 6 4 8.9 0.29 5.7e-01 ATXN1L HTR4 PBX3 SLC5A11 SNX32 UBA7
Age at last live birth 1.26 3 1 2.2 0.00 1.0e+00 AFAP1 MAPK4 UBA7
Leg pain on walking 1.07 1 0 0.0 0.00 1.0e+00 UBA7
Medication: Aspirin 2.06 2 1 2.2 -0.18 7.8e-01 FES OPRL1
Knee pain experienced in last month 1.20 2 1 2.2 0.00 1.0e+00 RP11-981P6.1 UQCC1
Hypertension (Self-reported) 6.07 143 92 204.4 0.98 4.1e-115 ABCA12 AC006111.1 AC091133.1 ACADVL ACE ACP2 ACTRT3 ADAM1A ADO ADRB1 ADRB2 AGT ANKS3 ARHGAP42 ARL17B ARNTL ATP2B1 BICC1 BRAP C10orf118 C11orf1 C22orf31 C4orf22 CACNB2 CENPW CERS5 CLCN6 CNNM2 CSK CTD-3032J10.3 CTSZ CYB5D1 DCAF16 DKFZp686O24166 ENPEP ERAP1 EXD1 FAM108C1 FCN3 FES FGF5 FURIN GAB1 GCHFR GLTP GLYR1 GOPC GOSR2 GTF2B GUCY1A3 HDAC7 HELLS HOXA10 HOXB9 HOXC8 HRCT1 HTR4 INO80 IRAK1BP1 ITGB5 KDM2B LA16c-358B7.3 LFNG LIMA1 LIME1 LSP1 MAPKAP1 MARK2 MED21 MRAS MTHFR NAA25 NAT15 NELFCD NME6 NMT1 NOC3L NPPA NPR3 NSUN6 NUDT16L1 NUP160 OIP5-AS1 OPRL1 PDXK PIGV PLCB1 PLEKHM2 PRDM8 PRKD3 PTPN12 RASIP1 RGS19 RHOC RP11-1055B8.4 RP11-332H18.4 RP11-379F4.7 RP11-588K22.2 RP11-819C21.1 RP11-981P6.1 RP13-514E23.2 RP4-605O3.4 RP4-635E18.7 RTF1 RYK SENP1 SENP3 SFXN2 SGOL1 SH2B3 SIPA1 SLC12A2 SLC25A37 SLC2A4 SLC4A7 SLC5A11 SNF8 SNX16 SNX31 SOX6 SPEN SWAP70 TBC1D19 TH1L THAP3 TMEM26 TNNI2 TNNT3 TP53INP1 TRIM47 TRIM59 TUBB1 UBAP1 UBE2Z UFL1 UPF3A VGLL4 WNT2B ZBTB46 ZNF318 ZNF443 ZNF831 ZNRF3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.17 1 0 0.0 0.00 1.0e+00 MARK2
Illnesses of father: Heart disease 2.07 6 3 6.7 0.77 8.6e-03 CDH13 FES RGS19 RP1-257A7.5 SMAD3 TCF21
Illnesses of siblings: Diabetes 1.18 1 1 2.2 0.00 1.0e+00 TCF7L2
Smoking status: Previous 1.16 2 1 2.2 0.00 1.0e+00 CADM2 SH2B3
Forced expiratory volume in 1-second (FEV1), predicted 1.43 7 5 11.1 -0.36 3.8e-01 ADCY3 CDK6 DCAF16 NUDT16L1 SRPK1 TCP11 UQCC1
Whole body fat-free mass 1.91 75 55 122.2 -0.53 1.0e-07 ADAM11 ADCY9 ADM ARVCF ATXN1L C10orf118 C17orf69 C2orf69 CADM2 CDK6 CENPW CGREF1 CNNM2 CSNK1G3 CTC-228N24.3 CYBRD1 CYTH1 DCAF16 DHX36 DNAJC18 DNAJC3-AS1 EFCAB13 FAM108C1 FBXW4 FHL3 FLJ33630 GAPVD1 GFER GLYR1 GOLGA1 HELLS HOXB3 MED28 NADK NFKBIA NMT1 NOV NPR3 NUDT16L1 OIP5-AS1 PEX1 PLCD3 PPP3R1 PPP6C PRRC2B RP11-179B2.2 RP11-332H18.4 RP11-373D23.3 RP13-514E23.2 RSRC2 S1PR2 SENP2 SEPT12 SFXN2 SH2B3 SLC12A2 SLC25A37 SLC35E2 SLC5A11 SLC9A3R2 SLFNL1 SMOC1 SNX11 SRPK1 TCP11 TEAD3 TMBIM1 TNS1 TRIM8 UBA7 UBE2Z UBN1 UPF3A UQCC1 ZNF500
Leg fat-free mass (right) 1.87 66 43 95.6 -0.44 4.4e-05 AC006547.14 ADAM11 ADCY9 ADM ARVCF C10orf118 C2orf69 CADM2 CDK6 CENPW CNNM2 CPEB4 CSNK1G3 CTC-228N24.3 CYBRD1 CYTH1 DCAF16 DHX36 DNAJC18 EFCAB13 FAM108C1 FHL3 FLJ33630 GAPVD1 GFER GLYR1 GOLGA1 HELLS HOXB3 KANSL1 NADK NFKBIA NMT1 NOV NPR3 NUDT16L1 PEX1 PLA2G4B PLCD3 PPP3R1 PPP6C PRRC2B RP11-179B2.2 RP11-332H18.4 RP11-981P6.1 RP13-514E23.2 RSRC2 SENP2 SEPT12 SFXN2 SLC12A2 SLC25A37 SLC35E2 SLC5A11 SLC9A3R2 SMOC1 SNX11 SRPK1 TCP11 TEAD3 TRIM8 UBA7 UBN1 UPF3A UQCC1 ZNF500
Arm fat percentage (left) 1.55 43 22 48.9 0.02 9.2e-01 ABHD17C AC091133.1 ACADVL ACP2 ADCY3 ADM AP001816.1 ARL17A ARNTL C6orf142 CHD6 DCAF16 DHX36 EDEM3 EXD1 FIBP GALNT4 GFPT1 GRB14 HOXA10 HOXC8 HTR4 KANSL1 MPP6 MYBPC3 NUP160 OIP5-AS1 PEPD POC1B POLL RERE RP11-981P6.1 RSRC2 SENP3 SFXN3 SLC5A11 SNF8 SNX32 TCF7L2 THAP3 TRIM47 TRIM73 UBA7
Handedness (chirality/laterality): Left-handed 1.31 3 2 4.4 0.00 1.0e+00 ARL17A NSF NSFP1
Mood swings 1.14 6 2 4.4 0.37 4.8e-01 ACP2 ARL17B NSF NUP160 SLC5A11 UBA7
Loneliness, isolation 1.23 2 1 2.2 0.00 1.0e+00 MYBPC3 NUP160
Ever had bowel cancer screening 1.03 1 0 0.0 0.00 1.0e+00 UBA7
Diabetes diagnosed by doctor 1.62 6 5 11.1 0.56 2.4e-01 DKFZp686O24166 HHEX PLA2G4B TCF7L2 UBA7 ZBTB46
Qualifications: nursing, teaching 1.00 1 0 0.0 0.00 1.0e+00 UBA7
Eye problems/disorders: Cataract 0.89 1 1 2.2 0.00 1.0e+00 SLC24A3
Mouth/teeth dental problems: Mouth ulcers 1.06 2 1 2.2 0.00 1.0e+00 ITGB3 TRIM59
Medication for cholesterol 3.13 18 8 17.8 -0.94 1.1e-09 AGT ARHGAP42 C4orf22 CGREF1 FES HOXA10 MC1R NUDT16L1 PIGV RASIP1 RHOC SENP1 SH2B3 TNNT3 WNT2B ZBTB46 ZNF500 ZNF831
Breast cancer (self-reported) 1.16 2 2 4.4 0.00 1.0e+00 SLC4A7 TOX3
Asthma (self-reported) 1.42 10 3 6.7 0.61 6.1e-02 AC074212.6 HHEX HTR4 OIP5-AS1 RERE RP5-1029K10.2 RTF1 SLC2A4RG SMAD3 TCP11
Medication: Aspirin 2.04 2 1 2.2 0.10 8.6e-01 FES OPRL1
Medication: Gliclazide 1.28 1 1 2.2 0.00 1.0e+00 TCF7L2
Illnesses of father: None of the above (group 1) 2.30 1 1 2.2 0.17 7.9e-01 FES
Smoking status: Current 1.42 4 1 2.2 -1.00 2.8e-03 GOLGA1 MAPKAP1 PBX3 PPP6C
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.32 7 4 8.9 -0.29 5.2e-01 ARL17B FBXO38 HTR4 NSF TCP11 TMEM170A UQCC1
Whole body water mass 1.92 73 59 131.1 -0.52 1.3e-07 ADAM11 ADCY9 ADM ARVCF ATXN1L C10orf118 C2orf69 CADM2 CDK6 CENPW CGREF1 CNNM2 CSNK1G3 CTC-228N24.3 CYBRD1 CYTH1 DCAF16 DHX36 DNAJC18 DNAJC3-AS1 FAM108C1 FBXW4 FHL3 FLJ33630 GAPVD1 GFER GLYR1 GOLGA1 HELLS HOXB3 MED28 NADK NFKBIA NMT1 NOV NPR3 NUDT16L1 OIP5-AS1 PEX1 PLCD3 PPP3R1 PPP6C PRRC2B RP11-179B2.2 RP11-332H18.4 RP11-373D23.3 RP13-514E23.2 RSRC2 S1PR2 SENP2 SEPT12 SFXN2 SH2B3 SLC12A2 SLC25A37 SLC35E2 SLC5A11 SLC9A3R2 SLFNL1 SMOC1 SNX11 SRPK1 TCP11 TEAD3 TMBIM1 TNS1 TRIM8 UBA7 UBE2Z UBN1 UPF3A UQCC1 ZNF500
Leg predicted mass (right) 1.88 67 44 97.8 -0.46 1.7e-05 AC006547.14 ADAM11 ADCY9 ADM ARVCF C10orf118 C2orf69 CADM2 CDK6 CENPW CNNM2 CPEB4 CSNK1G3 CTC-228N24.3 CYBRD1 CYTH1 DCAF16 DHX36 DNAJC18 EFCAB13 FAM108C1 FES FHL3 FLJ33630 FURIN GAPVD1 GFER GLYR1 GOLGA1 HELLS HOXB3 LRRC46 NADK NFKBIA NMT1 NOV NPR3 NUDT16L1 PEX1 PLA2G4B PLCD3 PPP3R1 PPP6C PRRC2B RP11-179B2.2 RP11-332H18.4 RP13-514E23.2 RSRC2 SENP2 SEPT12 SFXN2 SLC12A2 SLC25A37 SLC35E2 SLC5A11 SLC9A3R2 SMOC1 SNX11 SRPK1 TCP11 TEAD3 TRIM8 UBA7 UBN1 UPF3A UQCC1 ZNF500
Arm fat mass (left) 1.44 38 20 44.4 -0.15 3.3e-01 ABHD17C AC091133.1 ADCY3 ARL17A ARNTL CDK6 CNNM2 DHX36 ERAP1 FIBP GALNT4 GFPT1 GRB14 HTR4 KANSL1 MYBPC3 NADK OLA1 PEPD POC1B RP11-179B2.2 RP11-981P6.1 RSRC2 SFXN3 SLC25A37 SLC5A11 SLC9A3R2 SNX32 SRPK1 ST5 TCF7L2 TEAD3 THAP3 TRIM47 TRIM73 TRIM8 UBA7 UBN1
Number of self-reported non-cancer illnesses 2.25 10 3 6.7 0.91 2.4e-04 CLCN6 FBXO41 NUDT16L1 RGS19 RP5-1029K10.2 SH2B3 SLC2A4RG ZNF318 ZNF831 ZNRF3
Miserableness 1.11 5 1 2.2 0.42 4.8e-01 ACP2 ARL17B MMAB NUP160 UBA7
Guilty feelings 1.23 1 0 0.0 0.00 1.0e+00 ARNTL
Medication: Blood pressure 4.83 58 35 77.8 0.97 4.6e-44 ABCA12 ACE ACP2 ACTRT3 ADRB1 AGT ARHGAP42 ARL17B C11orf1 C4orf22 CACNB2 CENPW CLCN6 CNNM2 CSK CTD-3032J10.3 CYB5D1 EXD1 FAM108C1 FES FGF5 FURIN GTF2B GUCY1A3 HOXA10 HOXC8 JPH2 KAT5 KDM2B LFNG LIME1 LSP1 MC1R MRAS NME6 NUDT16L1 OPRL1 PDXK PIGV PLCB1 PRKD3 RHOC RP11-1055B8.4 RP11-588K22.2 RP11-819C21.1 SH2B3 SIPA1 SLC2A4RG SLC4A7 SLC7A1 TNNI2 TNNT3 WNT2B ZBTB46 ZNF318 ZNF500 ZNF831 ZNRF3
High cholesterol (Self-reported) 2.01 12 9 20.0 0.88 1.9e-06 ARHGAP42 CGREF1 DCAF16 OPRL1 PIGV RASIP1 RGS12 RGS19 SIDT2 SMARCA4 TMBIM1 TRIM47
Medication: Bendroflumethiazide 3.45 20 12 26.7 0.95 7.9e-14 ACP2 ARHGAP42 ATP2B1 CACNB2 CSK FES GFPT1 HOXA10 LSP1 PIGV PLCB1 RHOC SLC4A7 SLC7A1 TCF21 TNNI2 TNNT3 UBAP1 WNT2B ZNF831
Medication: Paracetamol 1.29 1 1 2.2 0.00 1.0e+00 ARL17B
Medication: Lisinopril 2.46 4 0 0.0 0.95 5.1e-02 ARHGAP42 LSP1 NME6 ZNF831
Illnesses of father: High blood pressure 2.73 3 1 2.2 0.99 1.1e-05 C4orf22 FES UPF3A
Ever smoked 1.33 3 1 2.2 0.00 1.0e+00 CADM2 GAPVD1 PDXDC2P
Basal metabolic rate 1.81 71 54 120.0 -0.49 2.0e-06 AC006547.14 ADAM11 ADCY9 ADM ARVCF ATXN1L C10orf118 C2orf69 CADM2 CDK6 CENPW CNNM2 CSNK1G3 CTC-228N24.3 CYBRD1 CYTH1 DCAF16 DHX36 DNAJC18 DNAJC3-AS1 FAM108C1 FHL3 FLJ33630 GAPVD1 GFER GLYR1 GOLGA1 HELLS HOXB3 MED28 NADK NFKBIA NMT1 NOV NPR3 NUDT16L1 PEX1 PLCD3 POLN PPP3R1 PPP6C PRRC2B RP11-179B2.2 RP11-332H18.4 RP11-373D23.3 RP13-514E23.2 RSRC2 S1PR2 SENP2 SEPT12 SFXN2 SH2B3 SLC12A2 SLC25A37 SLC35E2 SLC5A11 SLC9A3R2 SLFNL1 SNX11 SRPK1 ST5 TCP11 TEAD3 TNS1 TRIM8 UBA7 UBE2Z UBN1 UPF3A UQCC1 ZNF500
Leg fat percentage (left) 1.67 40 20 44.4 0.23 1.3e-01 ABHD17C ADCY3 ADM ARNTL CARF CRK CTC-228N24.3 DCAF16 EDEM3 EXD1 FIBP FLJ33630 GRB14 GTF2B HELLS HTR4 MAPKAP1 MPP6 MYBPC3 NMT1 NOV OIP5-AS1 PEPD POC1B RERE RP11-981P6.1 RSRC2 SFXN3 SLC12A2 SLC2A4RG SLC5A11 SLC9A3R2 SNX32 ST5 TCF7L2 THAP3 TRIM73 UBA7 UQCC1 WNT2B
Arm fat-free mass (left) 1.81 64 44 97.8 -0.44 7.1e-05 ADAM11 ADCY9 ADM ATXN1L C10orf118 CADM2 CDK6 CENPW CNNM2 CSNK1G3 CYBRD1 CYTH1 DCAF16 DHX36 DNAJC18 FAM108C1 FBXW4 FHL3 GAPVD1 GFER GLYR1 GOLGA1 HOXB3 LIME1 MED28 NADK NFKBIA NMT1 NOV PEX1 PLCD3 PPP3R1 PPP6C PRRC2B PSMB7 RP11-179B2.2 RP11-332H18.4 RP11-373D23.3 RP13-514E23.2 RSRC2 S1PR2 SENP3 SEPT12 SFXN2 SH2B3 SLC25A37 SLC2A4RG SLC35E2 SLC5A11 SLC9A3R2 SLFNL1 SNX11 SNX32 SRPK1 ST5 TCP11 TEAD3 TNS1 TRIM8 UBA7 UBE2Z UBN1 UPF3A UQCC1
Average weekly beer plus cider intake 1.07 2 1 2.2 0.00 1.0e+00 MYBPC3 UBA7
Risk taking 1.21 1 1 2.2 0.00 1.0e+00 CADM2
Diastolic blood pressure, automated reading 4.80 132 86 191.1 0.91 1.2e-60 AC006111.1 AC008865.1 AC010883.5 AC091133.1 AC099850.1 ACADVL ACP2 ADAM1A ADM ADO ADRB1 AGT AGTRAP ARHGAP42 ARNTL ATP2B1 BRAP C10orf118 C1orf84 C4orf22 C4orf3 CACNB2 CDH13 CENPW CERS5 CLCN6 CLIC4 CNNM2 CPEB4 CSK CSNK1G3 CTSZ CYB5D1 CYTH1 DCAF16 DULLARD EDEM3 EIF2AK4 ENPEP ERAP1 EXD1 FAM108C1 FBXO41 FES FGF5 FIBP FURIN GCHFR GLS GLTP GUCY1A3 HDAC7 HELLS HIBCH HOXA10 IGFBP3 INO80 IPO11 IRAK1BP1 ITGB5 ITSN1 KAT5 LFNG LIMA1 LIME1 LRIG2 LSP1 MAPKAP1 MAPKBP1 MECR MED19 MTHFR NAA25 NME6 NMT1 NOC3L NOV NSUN6 NUDT16L1 NUP160 OIP5-AS1 PLA2G4B PLEKHH2 POLI RABL2A RERE RGS19 RHOC RNF141 RNPS1 RP11-332H18.4 RP11-379F4.7 RP11-819C21.1 RP13-514E23.2 RP4-605O3.4 RP5-1029K10.2 RPL39P5 SEC31B SENP2 SH2B3 SIPA1 SIRT4 SLC15A2 SLC16A1 SLC24A3 SLC25A37 SLC2A4RG SLC5A11 SLC9A3R2 SLFNL1 SMG6 SMOC1 SNX32 SWAP70 TBC1D19 TEX2 TH1L TMEM26 TMEM87B TNNI2 TNNT3 TRAFD1 TRIM73 TRPV4 TSNARE1 TUBB1 UBA7 UBE2Z ULK4 WNT2B ZNF598 ZNF831
Myopia 1.21 1 0 0.0 0.00 1.0e+00 WNT2B
Vascular/heart problems diagnosed by doctor 5.91 130 82 182.2 -0.98 1.3e-102 ABCA12 AC006111.1 AC006547.14 AC091133.1 ACADVL ACE ACP2 ACTRT3 ADAM1A ADO ADRB1 ADRB2 AGT ANKS3 ARHGAP42 ARL17B ARNTL ATP2B1 BRAP C10orf118 C11orf1 C1orf84 C4orf22 CACNB2 CASC7 CENPW CERS5 CLCN6 CNNM2 CSK CTD-3032J10.3 CYB5D1 DCAF16 ENPEP ERAP1 EXD1 FAM108C1 FBXO41 FCN3 FES FGF5 FURIN GAB1 GCHFR GLTP GOPC GOSR2 GTF2B HDAC7 HOXA10 HOXB9 HOXC8 HRCT1 IBA57 INO80 IRAK1BP1 ITGB5 JPH2 KDM2B LA16c-358B7.3 LFNG LIME1 LSP1 MARK2 MED21 MRAS MTHFR NAA25 NAT15 NME6 NOC3L NPR3 NSUN6 NUDT16L1 NUP160 OIP5-AS1 OLA1 OPRL1 PDXK PIGV PLCB1 PRDM8 PRKD3 PTPN12 RASIP1 RGS19 RHOC RP11-379F4.7 RP11-588K22.2 RP11-819C21.1 RP4-605O3.4 RP4-635E18.7 RP5-1029K10.2 RSRC2 RTF1 RYK SENP1 SENP3 SFXN2 SH2B3 SIPA1 SLC17A6 SLC2A4 SLC4A7 SLC5A11 SNF8 SNX16 SOX6 SWAP70 TBC1D19 TCF21 TH1L THAP3 TMEM26 TNNI2 TNNT3 TP53INP1 TRAFD1 TRIM47 UBAP1 UBE2E3 UBE2Z UGT2B7 VGLL4 WNT2B ZBTB46 ZNF318 ZNF443 ZNF831 ZNRF3
Cholesterol lowering medication 1.87 7 3 6.7 0.97 9.0e-08 DCAF16 OPRL1 PIGV RGS19 SIDT2 SMARCA4 TCF7L2
Pain experienced in last month 1.23 2 1 2.2 0.00 1.0e+00 ATXN1L UFL1
Heart attack/myocardial infarction (self-reported) 1.78 4 2 4.4 0.53 2.2e-01 FES RP1-257A7.5 SH2B3 TCF21
Deep venous thrombosis (DVT) (self-reported) 1.25 1 1 2.2 0.00 1.0e+00 ATP1B1
Heart disease (siblings) 1.37 1 0 0.0 0.00 1.0e+00 FES
Impedance of whole body 1.80 73 55 122.2 0.42 4.0e-05 AC006547.14 ADCY3 ADM ARL17A ARL17B ARVCF ATF1 C17orf69 C2orf69 C4orf3 CADM2 CASC7 CERS5 CNNM2 CSNK1G3 CTC-228N24.3 CTD-3032J10.3 CTSO CYBRD1 CYP2C8 DDHD2 DKFZp686O24166 ELP4 FAM108C1 FER FIBP FLJ33630 GAPVD1 GOLGA1 GRB14 HELLS HOXB3 HOXC8 HOXD-AS1 LIMA1 LIME1 MC1R NADK NDUFS4 NEK4 NMT1 NNT NOC3L NSF NSFP1 OPRL1 PAFAH1B1 PASK PLA2G4B PLCD3 PPP6C PRKD3 PRRC2B RGS19 RP11-156P1.3 RP11-179B2.2 RP4-605O3.4 RP5-1029K10.2 RPS6KB1 RYK SCRN2 SENP1 SENP3 SLC12A2 SLC35E2 SNX32 SWAP70 TEAD3 TRIM73 TRIM8 UBA7 UQCC1 WNT2B
Leg fat mass (left) 1.46 35 22 48.9 -0.19 2.3e-01 ABHD17C ADCY3 ARNTL CARF CDK6 DHX36 ERAP1 FIBP GRB14 HTR4 MYBPC3 NADK OLA1 PEPD POC1B RERE RP11-179B2.2 RP11-981P6.1 RSRC2 SFXN3 SLC25A37 SLC2A4RG SLC5A11 SLC9A3R2 SNX32 SRPK1 ST5 TCF7L2 TEAD3 THAP3 TRIM73 TRIM8 UBA7 UBN1 WNT2B
Arm predicted mass (left) 1.81 65 43 95.6 -0.45 4.3e-05 ADAM11 ADCY9 ADM ATXN1L C10orf118 CADM2 CDK6 CENPW CNNM2 CSNK1G3 CYBRD1 CYTH1 DCAF16 DHX36 DNAJC18 FAM108C1 FBXW4 FHL3 GAPVD1 GFER GLYR1 GOLGA1 HELLS HOXB3 MED28 NADK NFKBIA NMT1 NOV PEX1 PLCD3 PPP3R1 PPP6C PRRC2B PSMB7 RP11-179B2.2 RP11-332H18.4 RP11-373D23.3 RP13-514E23.2 RPL39P5 RSRC2 S1PR2 SENP3 SEPT12 SFXN2 SH2B3 SLC25A37 SLC2A4RG SLC35E2 SLC5A11 SLC9A3R2 SLFNL1 SNX11 SNX32 SRPK1 ST5 TCP11 TEAD3 TMBIM1 TRIM8 UBA7 UBE2Z UBN1 UPF3A UQCC1

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 142 4.1 5.3
GTEx Adipose Visceral Omentum 91 4.5 5.5
GTEx Adrenal Gland 55 3.8 5.0
GTEx Artery Aorta 148 5.0 5.8
GTEx Artery Coronary 58 4.9 5.4
GTEx Artery Tibial 160 4.3 5.8
GTEx Brain Caudate basal ganglia 33 3.6 5.1
GTEx Brain Cerebellar Hemisphere 64 4.3 5.5
GTEx Brain Cerebellum 80 4.0 5.7
GTEx Brain Cortex 40 3.9 5.2
GTEx Brain Frontal Cortex BA9 42 4.5 5.8
GTEx Brain Hippocampus 21 4.0 5.1
GTEx Brain Hypothalamus 18 3.0 4.6
GTEx Brain Nucleus accumbens basal ganglia 28 3.2 5.0
GTEx Brain Putamen basal ganglia 22 3.5 4.9
GTEx Breast Mammary Tissue 77 3.9 5.1
GTEx Breast Mammary Tissue (Male) 53 4.4 5.3
GTEx Breast Mammary Tissue (Female) 73 4.4 5.1
GTEx Cells EBV-transformed lymphocytes 57 4.0 5.3
GTEx Cells Transformed fibroblasts 157 3.7 5.3
GTEx Colon Sigmoid 67 4.6 5.5
GTEx Colon Transverse 72 3.5 5.0
GTEx Esophagus Gastroesophageal Junction 66 4.6 5.7
GTEx Esophagus Mucosa 132 4.0 5.1
GTEx Esophagus Muscularis 131 4.1 5.2
GTEx Heart Atrial Appendage 57 3.6 5.0
GTEx Heart Left Ventricle 53 3.5 5.1
GTEx Liver 22 3.1 4.7
GTEx Lung 106 3.7 5.1
GTEx Muscle Skeletal 125 4.3 5.4
GTEx Nerve Tibial 162 3.7 4.9
GTEx Ovary 30 3.3 5.2
GTEx Pancreas 63 3.9 5.2
GTEx Pituitary 37 3.3 5.2
GTEx Prostate 35 4.2 5.5
GTEx Skin Not Sun Exposed Suprapubic 97 3.9 5.4
GTEx Skin Sun Exposed Lower leg 144 4.0 5.3
GTEx Small Intestine Terminal Ileum 19 4.1 4.9
GTEx Spleen 61 4.3 5.5
GTEx Stomach 71 4.9 5.8
GTEx Testis 129 4.1 5.3
GTEx Thyroid 151 3.8 5.1
GTEx Uterus 17 3.0 4.5
GTEx Vagina 26 4.1 5.3
GTEx Whole Blood 68 3.4 5.2
METSIM Adipose 135 2.9 4.5
NTR Blood 76 3.2 4.6
ROSMAP Brain Pre-frontal Cortex 169 3.8 5.4
YFS Blood 135 2.9 4.7
CommonMind Brain Pre-frontal Cortex 193 3.6 4.9
The Cancer Genome Atlas Bladder Urothelial Carcinoma 53 3.2 4.9
The Cancer Genome Atlas Breast Invasive Carcinoma 131 3.0 4.8
The Cancer Genome Atlas Cervical Squamous Cell Carcinoma 30 2.7 4.5
The Cancer Genome Atlas Colon Adenocarcinoma 70 3.4 5.1
The Cancer Genome Atlas Esophageal Carcinoma 23 3.4 4.5
The Cancer Genome Atlas Glioblastoma Multiforme 29 2.8 4.6
The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma 89 3.3 4.8
The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma 133 3.2 5.0
The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma 72 3.5 4.9
The Cancer Genome Atlas Brain Lower Grade Glioma 121 2.8 4.5
The Cancer Genome Atlas Liver Hepatocellular Carcinoma 33 3.0 4.3
The Cancer Genome Atlas Lung Adenocarcinoma 91 3.1 4.9
The Cancer Genome Atlas Lung Squamous Cell Carcinoma 68 2.7 4.6
The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma 47 2.9 4.7
The Cancer Genome Atlas Pancreatic Adenocarcinoma 59 3.5 4.9
The Cancer Genome Atlas Pheochromocytoma and Paraganglioma 36 2.7 4.5
The Cancer Genome Atlas Prostate Adenocarcinoma 131 2.8 4.5
The Cancer Genome Atlas Rectum Adenocarcinoma 21 3.0 4.5
The Cancer Genome Atlas Soft Tissue Sarcoma 33 3.1 4.6
The Cancer Genome Atlas Skin Cutaneous Melanoma 19 3.6 4.7
The Cancer Genome Atlas Stomach Adenocarcinoma 54 3.2 5.0
The Cancer Genome Atlas Testicular Germ Cell Tumors 38 3.0 4.9
The Cancer Genome Atlas Thyroid Carcinoma 149 2.9 4.6
The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma 13 2.5 4.2