Best TWAS P=5.38e-08 · Best GWAS P=9.53e-09 conditioned to 0.000775
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | POLI | 0.25 | 0.15 | blup | 43 | 0.18 | 2.6e-09 | 4.1 | -5.4 | 5.4e-08 | 0.63 | 0.51 | 0.43 | FALSE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | POLI | 0.13 | 0.07 | blup | 43 | 0.06 | 3.3e-04 | 3.5 | -5.4 | 5.4e-08 | 0.53 | 0.23 | 0.18 | TRUE |