Best TWAS P=2.67e-07 · Best GWAS P=2.53e-07 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | PHOSPHO2 | 0.17 | 0.15 | lasso | 3 | 0.15 | 2.0e-08 | 5.1 | -5.1 | 2.7e-07 | -1 | 0 | 1 | FALSE |
2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | PHOSPHO2 | 0.12 | 0.07 | lasso | 2 | 0.07 | 4.4e-08 | 5.1 | -5.2 | 2.7e-07 | -1 | 0 | 1 | TRUE |
3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | PHOSPHO2 | 0.08 | 0.07 | lasso | 3 | 0.07 | 5.7e-08 | 5.1 | -5.1 | 2.8e-07 | -1 | 0 | 1 | FALSE |