[Hub]/) : Traits : Systolic Blood Pressure :

chr4:106,265,432-107,966,499

Best TWAS P=9.24e-09 · Best GWAS P=9.88e-12 conditioned to 1.36e-09

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells EBV-transformed lymphocytes TBCK 0.24 0.21 lasso 10 0.19 8.8e-07 5.2 5.2 1.7e-07 -0.07 0.94 0.05 FALSE
2 GTEx Cells EBV-transformed lymphocytes AIMP1 0.32 0.19 lasso 16 0.16 7.8e-06 5.1 5.6 1.7e-08 -0.16 0.85 0.08 FALSE
3 The Cancer Genome Atlas Bladder Urothelial Carcinoma TBCK 0.05 0.05 blup 123 0.04 1.5e-04 5.1 5.1 2.7e-07 -0.08 0.04 0.95 FALSE
4 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TBCK 0.13 0.14 blup 123 0.14 3.9e-15 5.2 5.2 2.4e-07 -0.20 0.03 0.96 FALSE
5 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TBCK 0.06 0.05 blup 123 0.04 7.6e-06 5.1 5.2 2.6e-07 -0.18 0.04 0.96 FALSE
6 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma TBCK 0.05 0.03 blup 123 0.03 7.0e-03 5.1 5.7 9.2e-09 -0.14 0.03 0.71 TRUE
7 The Cancer Genome Atlas Lung Adenocarcinoma TBCK 0.05 0.08 lasso 1 0.07 1.0e-08 5.2 5.2 1.9e-07 -0.06 0.03 0.97 FALSE
8 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TBCK 0.09 0.14 enet 18 0.13 2.4e-14 5.1 5.2 1.5e-07 -0.11 0.04 0.96 FALSE
9 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma TBCK 0.09 0.06 blup 123 0.06 8.1e-05 5.1 5.4 7.0e-08 -0.14 0.03 0.95 FALSE
10 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma TBCK 0.18 0.12 lasso 1 0.08 6.3e-04 5.2 5.2 1.9e-07 -0.06 0.03 0.95 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma TBCK 0.09 0.14 lasso 3 0.14 1.2e-14 5.2 5.2 2.7e-07 -0.07 0.03 0.96 FALSE