Best TWAS P=1.93e-08 · Best GWAS P=2.1e-07 conditioned to 0.783
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | RERE | 0.20 | 0.23 | lasso | 2 | 0.24 | 1.7e-19 | 5.0 | 5.3 | 1.3e-07 | 0.97 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Breast Mammary Tissue | RERE | 0.19 | 0.08 | enet | 10 | 0.14 | 8.0e-08 | 5.1 | 5.2 | 2.3e-07 | 0.80 | 0.02 | 0.98 | FALSE |
| 3 | GTEx | Breast Mammary Tissue (Male) | RP5-1115A15.1 | 0.18 | 0.07 | lasso | 3 | 0.06 | 1.7e-02 | -3.8 | 5.3 | 1.1e-07 | 0.74 | 0.02 | 0.56 | FALSE |
| 4 | GTEx | Cells Transformed fibroblasts | RERE | 0.12 | 0.08 | lasso | 4 | 0.05 | 6.0e-05 | 5.2 | 5.3 | 1.5e-07 | 1.00 | 0.01 | 0.99 | FALSE |
| 5 | GTEx | Nerve Tibial | RERE | 0.12 | 0.09 | enet | 16 | 0.11 | 5.6e-08 | 5.2 | 5.6 | 1.9e-08 | 0.90 | 0.01 | 0.99 | TRUE |
| 6 | GTEx | Pancreas | RERE | 0.11 | 0.12 | lasso | 4 | 0.07 | 5.9e-04 | 5.1 | 5.2 | 1.9e-07 | 0.98 | 0.01 | 0.96 | FALSE |
| 7 | GTEx | Thyroid | RP5-1115A15.1 | 0.09 | 0.12 | lasso | 2 | 0.09 | 1.5e-07 | -4.8 | 5.1 | 2.7e-07 | 0.68 | 0.07 | 0.93 | FALSE |