TWAS hub - RERE

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.19900	0.0400	3.2e-12	0.234	NA	0.228	NA	0.239	4.4e-19	NA	1.4e-18	NA	1.7e-19
2	GTEx	Adipose Visceral Omentum	0.22000	0.0630	1.7e-06	0.166	NA	0.140	NA	0.167	5.8e-09	NA	1.0e-07	NA	5.2e-09
3	GTEx	Breast Mammary Tissue	0.19000	0.0600	5.6e-05	0.076	NA	0.144	NA	0.117	9.5e-05	NA	8.0e-08	NA	1.4e-06
4	GTEx	Breast Mammary Tissue (Male)	0.00941	0.0734	4.6e-01	-0.012	NA	-0.013	NA	-0.006	8.2e-01	NA	9.1e-01	NA	4.6e-01
5	GTEx	Breast Mammary Tissue (Female)	0.14306	0.0718	2.2e-02	0.115	NA	0.004	NA	0.079	2.6e-04	NA	2.3e-01	NA	2.4e-03
6	GTEx	Cells Transformed fibroblasts	0.12200	0.0410	1.7e-04	0.080	NA	0.038	NA	0.055	1.2e-06	NA	7.6e-04	NA	6.0e-05
7	GTEx	Esophagus Mucosa	0.12900	0.0400	6.4e-06	0.165	NA	0.142	NA	0.160	3.4e-11	NA	9.5e-10	NA	7.2e-11
8	GTEx	Lung	0.06840	0.0273	9.3e-04	0.055	NA	0.035	NA	0.046	5.0e-05	NA	9.9e-04	NA	2.0e-04
9	GTEx	Nerve Tibial	0.11670	0.0397	2.3e-04	0.089	NA	0.107	NA	0.101	6.8e-07	NA	5.5e-08	NA	1.3e-07
10	GTEx	Pancreas	0.11000	0.0510	8.0e-03	0.119	NA	0.070	NA	0.072	1.0e-05	NA	6.9e-04	NA	5.9e-04
11	GTEx	Skin Not Sun Exposed Suprapubic	0.12400	0.0510	8.8e-04	0.048	NA	0.027	NA	0.047	1.2e-03	NA	1.2e-02	NA	1.3e-03
12	GTEx	Skin Sun Exposed Lower leg	0.14100	0.0420	6.5e-07	0.049	NA	0.071	NA	0.079	6.0e-05	NA	1.8e-06	NA	4.2e-07
13	GTEx	Whole Blood	0.19400	0.0490	6.3e-09	0.146	NA	0.091	NA	0.133	2.4e-13	NA	9.2e-09	NA	2.7e-12
14	METSIM	Adipose	0.08470	0.0189	3.2e-15	0.116	0.121	0.130	0.128	0.134	5.9e-17	1.4e-17	6.1e-19	1.3e-18	1.8e-19
15	NTR	Blood	0.03960	0.0105	5.8e-11	0.038	0.034	0.031	0.034	0.035	2.5e-12	2.7e-11	1.8e-10	3.7e-11	2.0e-11
16	ROSMAP	Brain Pre-frontal Cortex	0.15070	0.0349	2.5e-14	0.150	0.136	0.146	0.144	0.148	7.4e-19	4.1e-17	2.4e-18	4.5e-18	1.5e-18
17	YFS	Blood	0.08890	0.0170	0.0e+00	0.154	0.122	0.155	0.150	0.157	7.9e-48	1.1e-37	1.8e-48	9.9e-47	5.7e-49
18	TCGA	Breast Invasive Carcinoma	0.02050	0.0113	2.2e-04	0.033	0.018	0.029	NA	0.031	2.4e-07	1.1e-04	1.1e-06	NA	4.7e-07
19	TCGA	Colon Adenocarcinoma	0.07500	0.0420	5.8e-03	0.004	0.031	0.003	NA	0.004	1.7e-01	6.8e-03	2.2e-01	NA	1.7e-01
20	TCGA	Esophageal Carcinoma	0.10300	0.0690	9.9e-03	0.072	0.061	0.018	NA	0.034	2.7e-03	5.2e-03	8.4e-02	NA	3.0e-02
21	TCGA	Lung Adenocarcinoma	0.05670	0.0336	4.4e-04	0.014	0.028	0.024	NA	0.025	8.4e-03	2.7e-04	6.4e-04	NA	5.6e-04
22	TCGA	Lung Squamous Cell Carcinoma	0.03610	0.0219	1.9e-03	0.017	0.024	0.008	NA	0.016	4.4e-03	8.7e-04	3.3e-02	NA	5.7e-03
23	TCGA	Pancreatic Adenocarcinoma	0.22300	0.1010	4.0e-04	0.040	0.074	0.070	NA	0.076	8.6e-03	4.9e-04	7.1e-04	NA	4.1e-04
24	TCGA	Prostate Adenocarcinoma	0.04280	0.0309	7.3e-03	0.006	0.009	0.000	NA	0.000	7.0e-02	3.1e-02	3.4e-01	NA	3.1e-01
25	TCGA	Uterine Corpus Endometrial Carcinoma	0.11700	0.0660	7.8e-03	0.014	0.029	0.031	NA	0.004	1.3e-01	5.3e-02	4.6e-02	NA	2.5e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Heel T-Score	20.6	164.2	256.0	-16.0	-14.1	-15.6	-10.8	-15.7	-13.1	-11.9	-15.6	-15.6	-11.3	-12.0	-13.7	-15.7	-13.4	-15.9	-14.7	-13.5	-3.0	-10.7	-10.4	-9.9	-15.6	-7.2	-9.1
Allergy or Eczema	18.0	47.3	73.4	7.6	7.3	6.9	4.0	7.1	8.1	8.0	7.0	7.5	6.4	7.0	8.2	8.6	7.6	7.1	8.3	7.8	3.2	7.6	5.0	6.1	7.9	3.9	6.6
Heel bone mineral density (BMD) T-score, automated (right)	15.9	36.5	58.5	-7.0	-7.1	-7.7	-5.8	-7.0	-6.5	-5.6	-6.7	-7.0	-4.9	-6.0	-6.7	-7.1	-6.5	-7.1	-7.0	-6.6	-1.7	-5.2	-5.1	-5.0	-7.2	-3.0	-4.5
Allergy	15.6	35.8	56.5	-6.3	-6.4	-6.3	-3.9	-6.0	-6.9	-6.9	-6.1	-6.5	-5.6	-6.3	-7.0	-7.5	-6.9	-6.3	-7.0	-6.5	-3.1	-6.4	-4.5	-5.8	-7.0	-3.1	-5.7
Respiratory disease	15.1	33.6	46.6	5.8	6.8	6.4	5.2	5.3	6.7	6.7	5.5	5.6	5.4	6.3	6.8	6.6	6.5	5.4	6.7	6.4	3.3	6.4	5.0	5.9	6.3	3.6	5.6
Hayfever, allergic rhinitis or eczema	14.6	31.7	49.8	6.3	6.0	5.6	3.1	6.0	6.8	6.3	5.8	6.4	4.8	5.7	6.9	7.1	6.2	6.1	6.9	6.4	2.3	5.8	3.8	5.0	6.8	2.9	5.4
Asthma	12.5	24.7	36.1	4.7	5.9	5.5	4.2	4.1	5.9	5.8	4.4	4.6	4.9	5.6	5.9	5.7	5.6	4.5	5.7	5.5	3.4	6.0	4.2	5.2	5.4	2.9	4.8
Tense / ‘highly strung’	12.3	20.4	27.7	-4.6	-4.9	-4.9	-3.7	-4.2	-5.0	-5.2	-3.9	-4.2	-4.6	-4.9	-5.0	-5.3	-5.2	-4.6	-5.1	-5.0	-2.6	-4.8	-4.1	-4.7	-5.1	-3.7	-4.2
Asthma (self-reported)	12.3	24.4	35.1	4.6	5.9	5.4	4.3	4.0	5.9	5.7	4.3	4.5	4.8	5.5	5.9	5.6	5.6	4.5	5.7	5.5	3.5	5.9	4.2	5.2	5.4	3.1	4.7
Diastolic blood pressure, automated reading	12.2	37.9	61.3	7.5	6.9	6.8	4.8	7.2	6.8	5.9	7.2	7.0	4.6	6.2	7.0	7.0	6.7	7.5	7.6	7.1	1.9	4.8	5.2	5.4	7.8	4.1	3.9
Heel bone mineral density (BMD) T-score, automated (left)	11.9	26.9	45.3	-6.2	-6.2	-6.7	-5.4	-6.3	-5.4	-4.5	-6.2	-6.1	-4.4	-4.5	-5.6	-6.1	-5.2	-6.4	-6.0	-5.6	-1.3	-4.2	-4.5	-4.0	-6.3	-2.9	-3.0
Blood Eosinophil Count	10.6	81.4	125.4	9.9	10.5	8.4	6.6	8.7	11.1	9.7	8.7	8.3	8.1	9.4	11.2	9.9	9.6	9.2	11.1	10.7	5.0	8.9	8.7	8.2	10.6	7.0	8.7
Depression (self-reported)	10.5	12.6	20.8	-3.9	-3.4	-3.3	-1.2	-3.5	-4.5	-4.4	-3.3	-3.8	-2.8	-3.8	-4.6	-4.5	-4.1	-3.8	-4.3	-4.2	-1.5	-4.0	-2.0	-3.2	-4.3	-1.6	-3.9
Smoking Status	9.5	22.7	39.3	6.0	5.6	5.3	4.1	5.5	5.5	3.7	5.0	5.1	3.5	4.8	5.6	5.2	5.1	6.0	5.9	5.7	1.6	3.6	4.4	3.6	6.3	3.7	2.5
Depression (Nagel 2018)	8.5	12.8	27.9	-4.9	-3.3	-4.1	-1.2	-4.9	-4.1	-3.8	-3.9	-5.3	-2.3	-2.5	-4.3	-5.1	-3.5	-4.8	-4.2	-3.8	-0.0	-3.0	-1.2	-2.5	-4.6	-0.6	-2.2
Loneliness, isolation	8.4	11.6	19.3	-4.1	-3.5	-3.9	-2.0	-3.8	-4.0	-3.7	-4.0	-3.7	-2.3	-3.1	-4.1	-4.4	-3.8	-4.0	-4.3	-4.0	-1.1	-3.2	-2.5	-2.9	-4.2	-1.7	-2.3
Systolic blood pressure, automated reading	8.3	24.1	44.6	6.6	5.2	5.5	3.0	6.5	5.5	4.4	5.8	6.7	3.2	4.4	5.7	6.1	5.0	6.4	6.2	5.5	0.6	3.6	3.1	3.8	6.3	2.2	2.9
Frequency of depressed mood in last 2 weeks	8.2	11.4	19.4	-4.0	-3.6	-3.7	-1.8	-3.8	-4.2	-4.0	-3.1	-4.0	-2.3	-3.1	-4.3	-4.4	-3.5	-3.8	-4.3	-4.0	-1.2	-3.5	-1.9	-3.0	-4.1	-1.5	-2.5
Leg fat percentage (right)	8.0	29.1	47.1	6.0	6.0	5.3	3.6	5.6	6.4	6.3	4.6	5.3	4.5	5.4	6.5	6.0	5.9	5.8	6.9	6.6	3.4	5.0	4.5	5.1	6.6	4.8	4.4
Leg fat percentage (left)	7.9	28.7	46.0	5.8	6.0	5.2	3.6	5.4	6.4	6.3	4.3	5.2	4.4	5.5	6.5	5.9	5.8	5.7	6.8	6.5	3.4	5.0	4.5	5.2	6.5	4.7	4.7
Schizophrenia (2014)	7.7	16.9	31.6	5.3	4.5	5.2	3.1	5.3	4.6	3.4	5.6	5.2	2.5	4.2	4.7	5.0	4.2	5.0	4.9	4.3	0.0	3.3	3.0	2.7	5.0	1.4	3.1
Wheeze or whistling in the chest in last year	7.7	13.7	20.0	3.8	4.5	4.4	3.8	3.7	4.0	3.7	4.0	3.9	3.6	3.5	4.0	4.3	4.2	3.8	4.2	4.2	2.1	4.0	3.2	3.5	4.3	1.8	2.6
Suffer from ‘nerves’	7.7	12.0	19.0	-4.4	-3.4	-3.7	-1.8	-4.3	-3.9	-3.7	-3.5	-4.2	-2.9	-3.4	-4.0	-4.3	-3.6	-4.2	-4.2	-3.9	-0.9	-3.1	-2.6	-2.6	-4.3	-2.2	-3.2
Miserableness	7.7	13.4	24.9	-3.7	-4.3	-4.0	-2.9	-3.4	-4.5	-4.2	-2.8	-3.0	-2.6	-3.3	-4.5	-3.6	-3.8	-3.7	-4.8	-5.0	-2.5	-3.2	-3.6	-3.9	-4.5	-3.2	-3.1
Depressed Affect (Nagel 2018)	7.4	15.6	27.1	-4.5	-4.2	-4.4	-2.4	-4.2	-4.9	-4.7	-3.6	-4.3	-2.7	-3.6	-4.9	-4.6	-3.9	-4.2	-5.2	-5.1	-1.5	-4.1	-2.9	-3.5	-4.7	-1.9	-3.9
Neuroticism (Nagel 2018)	6.9	16.2	29.2	-5.4	-4.0	-4.8	-2.2	-5.2	-4.5	-4.4	-4.6	-5.1	-2.3	-3.3	-4.7	-5.1	-4.0	-5.1	-5.1	-4.7	-0.3	-3.3	-2.6	-2.8	-4.9	-1.5	-3.3
Hypothyroidism (self reported)	6.8	15.6	25.8	-4.6	-4.2	-3.6	-2.0	-4.2	-4.9	-4.5	-3.7	-4.4	-3.2	-4.1	-4.9	-5.0	-4.4	-4.0	-5.1	-4.7	-1.2	-4.3	-2.7	-3.5	-4.5	-1.5	-4.2
Neuroticism	6.7	16.1	28.0	-5.3	-4.0	-4.9	-2.0	-4.9	-4.7	-4.3	-4.5	-5.0	-2.4	-3.6	-4.8	-5.3	-4.1	-4.9	-5.0	-4.5	-0.5	-3.5	-2.4	-3.1	-4.9	-1.4	-3.3
Body fat percentage	6.7	26.4	43.7	6.2	5.6	5.3	3.3	6.0	5.9	5.6	5.0	5.8	3.9	4.9	6.1	5.9	5.5	6.0	6.6	6.2	2.3	4.1	3.9	4.5	6.5	3.9	4.0
Systolic Blood Pressure	6.5	32.3	55.8	7.5	6.1	6.6	3.8	7.2	6.3	5.6	7.0	7.2	4.0	4.9	6.6	7.1	6.0	7.3	6.7	6.2	1.0	4.5	3.8	4.5	7.2	2.5	3.4
Ever had bowel cancer screening	6.3	7.4	12.6	-2.4	-3.5	-2.6	-2.6	-2.2	-3.6	-2.7	-2.4	-2.1	-2.5	-2.9	-3.5	-2.4	-2.8	-2.3	-3.3	-3.6	-2.0	-2.7	-3.1	-2.9	-3.1	-2.1	-2.6
Schizophrenia (2018)	6.2	12.9	25.3	4.8	3.7	4.8	2.5	4.8	3.8	3.0	4.9	5.0	2.2	3.5	3.9	4.8	3.7	4.4	4.1	3.5	-0.3	3.0	2.3	2.3	4.2	0.5	2.8
Current tobacco smoking	6.2	10.1	17.4	4.0	3.5	3.4	2.1	3.6	3.8	2.4	3.9	3.5	2.8	3.1	3.9	3.3	3.1	3.9	4.0	3.9	1.3	3.0	2.8	2.0	4.2	2.4	1.6
Frequency of tiredness / lethargy in last 2 weeks	6.2	10.1	19.9	-4.0	-3.4	-3.1	-1.1	-3.5	-4.4	-3.1	-2.7	-3.1	-1.5	-3.3	-4.5	-3.4	-3.3	-3.8	-4.4	-4.1	-1.0	-2.2	-2.6	-2.7	-4.3	-2.3	-2.4
Ever highly irritable/argumentative for 2 days	6.2	7.4	12.5	-3.0	-3.0	-3.2	-2.4	-2.8	-2.6	-2.9	-3.0	-2.8	-2.4	-2.5	-2.7	-3.2	-3.1	-3.4	-3.0	-3.0	-1.7	-2.2	-2.4	-2.8	-3.5	-2.3	-1.9
Average weekly champagne plus white wine intake	6.2	8.5	17.7	-3.9	-2.9	-2.8	-1.2	-3.7	-3.5	-2.3	-4.0	-3.5	-1.7	-2.6	-3.6	-3.1	-3.0	-4.0	-3.8	-3.8	0.0	-1.3	-2.4	-2.2	-4.2	-1.2	-1.6
Ever had prostate specific antigen (PSA) test	6.2	7.1	13.0	-3.4	-3.0	-2.9	-1.5	-3.4	-3.5	-2.7	-2.1	-3.3	-1.5	-2.7	-3.5	-3.1	-2.9	-3.3	-3.4	-3.3	-0.2	-1.7	-2.1	-1.9	-3.6	-1.7	-1.6
Hypothyroidism/myxoedema (self-reported)	6.1	12.0	21.8	-4.3	-3.5	-3.2	-1.3	-4.0	-4.3	-4.0	-3.6	-4.2	-2.6	-3.3	-4.4	-4.7	-3.7	-3.7	-4.4	-3.9	-0.7	-3.7	-1.6	-2.8	-4.0	-1.2	-3.8
Neuroticism score	6.0	12.6	21.4	-4.5	-3.5	-4.0	-1.7	-4.2	-4.2	-4.1	-3.7	-4.1	-2.2	-3.4	-4.3	-4.5	-3.7	-4.2	-4.6	-4.2	-0.9	-3.2	-2.4	-2.8	-4.3	-1.7	-3.1
Leg fat mass (right)	6.0	23.1	36.4	4.8	5.4	4.5	3.5	4.5	5.6	5.8	3.4	4.2	4.2	5.1	5.7	5.1	5.5	4.8	6.0	6.0	3.8	4.6	4.2	4.9	5.7	4.7	4.5
Leg fat mass (left)	6.0	23.5	37.0	4.8	5.4	4.5	3.5	4.4	5.7	5.9	3.4	4.2	4.2	5.2	5.8	5.1	5.5	4.8	6.1	6.0	3.8	4.6	4.2	5.0	5.7	4.7	4.6
Schizophrenia vs Biploar Disorder	5.9	7.7	13.5	2.9	3.4	2.8	2.6	2.5	3.4	2.4	2.5	2.6	2.0	3.6	3.4	2.9	3.0	2.7	3.7	3.5	1.2	2.9	2.9	2.6	3.2	1.7	2.4
Hypertension (Self-reported)	5.9	16.3	29.5	4.4	4.3	3.5	1.9	4.0	5.4	5.2	3.6	4.0	3.1	3.8	5.4	4.7	4.7	4.0	5.0	4.8	2.6	4.3	2.9	3.8	4.7	2.9	3.2
Trunk fat percentage	5.8	23.1	39.7	6.1	5.1	5.0	2.9	6.0	5.5	4.9	5.0	5.7	3.3	4.4	5.6	5.6	5.0	5.9	6.2	5.8	1.7	3.4	3.5	4.0	6.3	3.4	3.5
Medication: Levothyroxine sodium	5.7	9.7	15.9	-3.6	-3.4	-2.8	-1.6	-3.3	-3.9	-3.3	-3.0	-3.4	-2.2	-3.3	-4.0	-4.0	-3.5	-3.2	-4.0	-3.7	-1.0	-3.4	-2.0	-2.6	-3.6	-1.6	-3.5
Seen doctor (GP) for nerves, anxiety, tension or depression	5.7	8.7	15.3	-2.9	-3.2	-2.8	-1.5	-2.7	-3.8	-3.9	-2.3	-2.6	-2.3	-3.1	-3.8	-3.2	-3.3	-2.9	-3.7	-3.7	-2.1	-3.0	-2.5	-3.1	-3.5	-2.3	-2.9
Illnesses of father: High blood pressure	5.7	7.0	12.5	2.6	3.1	3.1	2.5	2.7	2.9	3.2	2.9	2.7	3.5	2.0	2.9	2.9	2.8	2.6	2.8	2.8	1.6	2.8	2.5	2.7	2.9	1.9	1.6
High blood pressure	5.5	15.4	28.8	4.3	4.2	3.4	1.8	3.9	5.3	5.0	3.4	3.9	2.9	3.7	5.4	4.5	4.5	3.9	5.0	4.8	2.5	4.2	2.9	3.8	4.6	2.7	3.1
Frequency of tenseness / restlessness in last 2 weeks	5.5	8.6	14.6	-3.6	-3.3	-3.2	-2.1	-3.6	-3.4	-3.0	-2.8	-3.3	-1.9	-2.6	-3.5	-3.5	-3.1	-3.7	-3.8	-3.6	-0.8	-2.3	-2.2	-2.4	-3.8	-2.2	-1.3
Arm fat percentage (left)	5.5	22.1	37.5	5.5	5.1	4.5	2.8	5.3	5.7	5.3	4.4	5.0	3.6	4.4	5.8	5.3	5.0	5.3	6.1	5.9	2.4	3.9	3.7	4.2	6.0	3.7	3.6
Number of operations (self-reported)	5.5	8.1	16.6	-3.3	-2.7	-2.5	-0.6	-2.7	-3.8	-2.9	-2.3	-2.6	-1.1	-3.6	-3.8	-3.1	-3.0	-2.7	-4.0	-3.9	-1.0	-2.9	-2.4	-2.4	-3.4	-0.9	-4.1
Vascular/heart problems diagnosed by doctor	5.5	15.1	28.4	-3.9	-4.2	-3.1	-1.7	-3.5	-5.3	-5.1	-3.0	-3.5	-3.2	-3.8	-5.3	-4.3	-4.6	-3.6	-5.0	-4.9	-2.9	-4.3	-3.0	-4.0	-4.5	-3.0	-3.0
Hair/balding pattern: Pattern 4	5.3	12.9	24.9	3.7	4.3	3.2	2.4	3.3	5.0	4.2	2.7	3.1	2.6	4.3	5.0	3.7	3.9	3.2	4.8	4.7	1.6	3.4	3.4	3.3	4.0	2.7	3.4
Neck or shoulder pain in last month	5.3	7.5	18.2	-2.6	-2.9	-1.4	-0.3	-2.1	-4.3	-2.7	-1.7	-2.0	-1.6	-3.8	-4.2	-2.3	-2.8	-2.4	-4.0	-3.9	-1.5	-2.5	-2.2	-2.6	-3.4	-2.3	-3.4
Smoking status: Current	5.3	8.4	14.1	3.7	3.3	3.1	2.0	3.2	3.5	2.2	3.5	3.1	2.6	2.8	3.6	3.0	2.8	3.5	3.6	3.5	1.3	2.9	2.5	1.9	3.8	2.3	1.5
Qualifications: NVQ or HND or HNC or equivalent	5.1	6.2	13.0	2.9	3.0	2.2	1.4	2.4	3.6	2.5	2.4	2.4	1.5	2.7	3.6	3.1	2.6	2.5	3.4	3.0	0.9	2.4	1.8	2.1	3.1	1.6	1.5
Eye problems/disorders: Glaucoma	5.1	6.1	10.9	3.2	2.8	2.8	2.5	3.1	2.4	1.8	3.3	2.6	1.8	2.2	2.5	2.7	2.4	3.2	2.9	2.7	0.6	1.5	2.7	1.8	3.2	2.1	1.6
Reaction Time	4.9	9.4	18.3	4.3	3.4	3.8	2.3	4.0	3.3	2.4	4.0	4.0	2.1	2.5	3.5	3.9	2.8	4.0	3.8	3.5	0.2	2.2	2.3	1.9	4.0	1.4	1.0
Lupus	4.7	7.2	14.7	3.7	2.6	2.2	0.5	3.8	3.5	2.4	2.9	3.5	0.9	2.2	3.6	2.8	2.3	3.6	3.6	3.2	0.4	1.4	1.5	1.8	3.7	2.1	2.5
Arm fat percentage (right)	4.7	18.5	31.6	5.0	4.7	4.0	2.5	4.8	5.3	4.9	3.8	4.5	3.4	4.1	5.3	4.7	4.5	4.8	5.6	5.4	2.4	3.5	3.5	4.0	5.5	3.6	3.4
Mean time to correctly identify matches	4.7	8.9	17.8	4.0	3.2	3.9	2.7	4.0	2.7	2.4	4.2	4.1	2.5	2.2	2.9	3.8	2.8	3.9	3.5	3.1	0.1	2.3	2.3	2.0	3.6	1.4	0.8
Illnesses of siblings	4.6	6.5	14.3	-3.6	-2.5	-2.7	-1.2	-3.6	-2.9	-2.5	-3.4	-3.8	-1.5	-2.3	-3.1	-3.1	-2.6	-3.4	-3.0	-2.6	0.5	-1.7	-1.3	-1.5	-3.2	-0.7	-1.8
Whole body fat mass	4.6	19.1	31.1	4.8	4.8	4.4	3.1	4.6	5.0	5.0	3.7	4.3	3.5	4.4	5.1	4.7	4.8	4.8	5.6	5.4	2.7	3.6	3.7	4.2	5.4	4.0	3.7
Cardiovascular Disease	4.5	14.9	26.8	3.6	4.2	3.5	2.5	3.0	4.8	5.2	3.1	3.0	3.5	4.1	4.8	4.2	4.5	3.4	4.7	4.5	3.5	4.8	3.2	4.2	4.2	3.3	3.6
Seen a psychiatrist for nerves, anxiety, tension or depression	4.5	5.8	11.0	-2.6	-2.1	-1.9	-0.1	-2.1	-3.3	-3.0	-2.2	-2.2	-1.2	-3.1	-3.3	-3.0	-2.7	-2.4	-3.1	-3.0	-1.0	-2.5	-1.7	-2.2	-2.8	-1.2	-3.0
Medication: Ventolin 100micrograms inhaler	4.3	5.5	11.0	2.4	2.5	2.2	1.1	2.0	3.1	3.3	2.0	2.2	1.7	2.1	3.1	3.0	2.7	2.4	2.8	3.0	1.7	2.9	1.2	2.2	2.9	1.2	2.0
Worry (Nagel 2018)	4.2	8.9	15.9	-4.0	-2.9	-3.6	-1.7	-3.8	-3.2	-3.2	-3.2	-3.8	-2.1	-2.8	-3.3	-3.8	-3.1	-3.8	-3.7	-3.4	-0.3	-2.5	-2.1	-2.1	-3.7	-1.4	-2.3
Leg pain on walking	4.2	5.3	8.2	2.1	2.9	2.5	2.2	2.1	2.6	2.5	1.4	2.0	2.8	2.4	2.6	2.7	2.5	2.0	2.6	2.8	1.4	2.7	2.2	2.3	2.5	1.2	2.2
Peak expiratory flow (PEF)	4.1	9.6	15.1	-2.8	-3.9	-3.2	-3.2	-2.5	-3.6	-3.5	-2.5	-2.3	-2.8	-3.2	-3.6	-2.8	-3.5	-2.8	-3.8	-3.8	-2.5	-3.1	-3.5	-3.3	-3.4	-3.2	-2.1
Arm fat mass (left)	4.1	16.9	27.2	4.1	4.6	3.8	2.9	3.9	4.8	5.0	3.1	3.6	3.6	4.3	4.9	4.2	4.6	4.2	5.2	5.2	3.1	3.6	3.8	4.2	5.0	4.2	3.7
Medication: Bendroflumethiazide	4.1	6.2	11.9	2.2	2.8	2.2	2.0	2.2	2.8	3.5	2.1	2.2	2.6	2.3	2.8	2.8	2.9	2.3	2.6	2.8	2.5	3.2	2.1	2.5	2.7	1.9	2.3
Bipolar Disorder or Schizophrenia	4.0	9.7	20.3	4.1	3.1	3.7	1.9	3.8	3.3	2.9	4.5	3.7	2.6	3.0	3.4	3.9	3.2	3.7	3.6	3.2	0.1	2.6	2.4	2.2	3.7	1.3	3.1
Chronotype (morning person)	4.0	9.2	16.5	2.6	3.3	2.9	1.6	2.2	4.1	3.7	2.1	2.2	2.8	3.7	4.0	3.1	3.2	2.3	3.7	3.7	2.2	3.9	2.3	3.0	3.2	2.4	4.0
Trunk fat mass	4.0	17.1	27.9	4.8	4.5	4.2	2.8	4.6	4.7	4.6	3.7	4.3	3.2	4.1	4.8	4.5	4.6	4.8	5.3	5.1	2.3	3.2	3.3	3.9	5.3	3.7	3.4
Exposure to tobacco smoke at home	4.0	4.5	11.3	1.1	2.5	1.8	2.6	0.5	2.0	2.3	1.1	0.7	3.4	2.5	1.9	1.8	2.5	1.2	1.8	2.2	2.7	2.9	2.4	2.6	1.8	2.6	2.1
Mouth/teeth dental problems: Loose teeth	4.0	4.8	9.1	2.9	2.5	2.6	1.7	2.5	2.5	1.3	3.0	2.6	1.2	2.3	2.6	2.4	1.9	2.8	2.8	2.6	0.5	1.6	1.7	1.6	2.9	1.2	1.6
Type 2 Diabetes (T2D) (2012)	3.9	4.5	7.6	2.7	2.1	2.1	0.9	2.5	2.2	2.5	2.5	2.5	2.1	1.8	2.4	2.8	2.4	2.8	2.5	2.1	0.4	1.7	1.9	1.7	2.7	1.2	1.8
Serious illness, injury or assault of a close relative in last 2 years	3.9	4.5	11.2	-1.7	-2.7	-3.3	-3.3	-1.8	-1.6	-2.5	-2.2	-2.0	-2.3	-1.5	-1.7	-2.4	-2.4	-2.1	-1.6	-1.9	-1.7	-2.1	-1.8	-2.4	-2.2	-1.7	-1.5
High blood pressure (siblings)	3.9	5.6	12.6	3.3	2.6	2.2	1.6	3.5	2.7	2.4	3.5	3.5	2.2	1.5	2.8	2.8	2.1	3.0	2.5	2.1	-0.3	1.5	1.3	1.3	2.8	1.3	1.6
Migraine (self-reported)	3.9	4.8	10.5	-2.6	-2.2	-1.3	-0.2	-2.2	-3.2	-1.8	-1.7	-1.9	-0.9	-2.9	-3.2	-1.9	-2.5	-2.4	-3.2	-3.1	-0.6	-1.3	-2.3	-2.0	-3.1	-1.6	-2.1
Major Depression (MDD)	3.7	4.5	8.8	-2.8	-1.8	-2.0	0.2	-2.7	-2.9	-2.6	-2.5	-2.8	-1.2	-1.7	-3.0	-2.8	-2.1	-2.6	-2.4	-2.1	-0.5	-2.0	-0.7	-1.3	-2.6	-0.7	-2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	3.7	4.9	9.5	-2.9	-2.2	-2.6	-1.1	-2.8	-2.5	-2.2	-2.3	-3.0	-1.1	-1.9	-2.6	-3.1	-2.4	-3.0	-2.7	-2.5	-0.4	-1.8	-0.9	-1.8	-3.0	-0.7	-1.2
Past tobacco smoking	3.7	6.9	11.9	-2.9	-3.1	-3.2	-2.7	-2.8	-2.7	-2.2	-2.4	-2.6	-1.8	-2.9	-2.8	-2.9	-3.2	-3.4	-2.9	-2.8	-1.5	-1.9	-2.6	-2.5	-3.5	-2.4	-1.5
Pain all over the body in last month	3.7	4.0	8.2	0.8	2.7	1.4	2.5	0.4	2.4	1.9	0.7	0.1	2.0	2.7	2.3	1.2	2.4	0.5	2.2	2.4	2.6	2.5	2.9	2.4	1.5	2.6	1.7
Arm fat mass (right)	3.6	14.9	24.3	3.9	4.3	3.5	2.8	3.7	4.6	4.6	2.8	3.4	3.4	4.0	4.6	3.9	4.3	3.9	4.9	4.9	2.9	3.3	3.6	4.0	4.7	4.0	3.4
Medication: Seretide 50 evohaler	3.6	4.2	12.1	3.1	1.8	2.6	0.8	3.2	2.1	0.6	2.9	3.5	0.9	1.4	2.2	2.6	1.4	3.2	2.4	2.2	-0.7	0.8	0.5	0.6	2.9	0.2	0.2
Townsend deprivation index at recruitment	3.5	4.9	9.5	2.3	2.3	3.1	2.2	2.3	2.0	2.4	2.8	2.5	2.3	2.0	2.0	2.5	2.4	2.5	2.3	2.3	1.2	2.1	1.9	2.0	2.6	1.6	1.4
Medication: Atenolol	3.5	4.4	11.1	2.2	1.9	2.1	0.8	2.1	2.4	3.3	2.1	2.4	1.9	1.8	2.4	3.0	2.6	2.2	1.9	1.8	1.0	2.8	0.6	1.9	2.1	0.6	2.8
Pulse rate	3.5	5.9	9.4	2.9	2.7	2.7	2.4	2.9	2.2	2.6	2.4	2.7	2.2	2.6	2.3	3.0	2.6	3.1	2.8	2.6	0.9	2.0	2.1	2.0	2.9	1.8	2.0
Number of full brothers	3.5	4.3	8.8	1.4	2.9	2.1	2.7	1.1	2.4	2.2	1.4	1.0	2.6	2.5	2.3	1.7	2.1	1.3	2.2	2.2	1.8	2.5	3.0	2.3	1.9	1.8	2.0
Irritability	3.5	5.9	11.2	-3.1	-2.2	-2.9	-1.2	-3.0	-2.3	-3.0	-3.4	-3.0	-1.5	-2.2	-2.4	-3.3	-2.8	-3.3	-2.6	-2.6	-0.7	-2.0	-1.2	-2.0	-3.1	-1.0	-2.0
Body mass index (BMI)	3.4	14.7	26.6	3.5	4.3	3.0	2.4	3.1	4.9	5.2	2.0	2.9	3.3	4.1	4.9	3.8	4.4	3.4	4.9	4.9	3.4	3.9	3.2	4.2	4.4	4.0	3.8
Age at First Birth	3.3	4.7	16.2	-0.9	-2.8	-1.5	-2.7	-0.5	-2.2	-1.7	-0.7	-0.0	-2.0	-2.6	-2.1	-0.7	-2.3	-1.2	-2.4	-2.7	-3.0	-1.7	-3.6	-2.9	-2.1	-4.0	-1.6
Pack years adult smoking proportion	3.3	5.1	11.9	1.1	3.2	2.0	3.4	0.8	2.4	2.2	1.1	0.3	2.1	2.3	2.3	1.0	2.3	1.3	2.4	2.8	3.4	2.2	3.1	2.5	2.2	3.4	1.2
Forced expiratory volume in 1-second (FEV1), Best measure	3.3	10.5	17.8	-2.6	-4.2	-3.0	-3.4	-2.3	-3.9	-3.7	-2.2	-2.1	-3.5	-3.0	-3.9	-2.8	-3.5	-2.5	-3.8	-3.9	-3.3	-3.6	-3.6	-3.6	-3.5	-3.8	-2.4
Qualifications: College or University degree	3.3	10.3	22.5	-2.8	-4.5	-4.4	-4.7	-2.8	-3.2	-2.5	-3.2	-2.7	-3.2	-2.9	-3.2	-2.9	-3.2	-3.2	-3.4	-3.9	-2.5	-2.6	-3.4	-3.2	-4.0	-3.2	-0.9
Number of full sisters	3.3	4.1	10.5	1.7	2.3	1.1	0.4	1.1	3.2	2.0	0.8	1.2	1.8	2.2	3.2	1.8	1.7	1.2	2.8	2.8	1.7	2.7	1.7	1.8	2.2	1.7	3.0
Alcohol drinker status: Previous	3.3	3.7	9.4	-2.7	-1.4	-1.9	-0.4	-2.7	-1.9	-1.2	-2.5	-2.8	-1.1	-1.3	-2.0	-2.6	-2.3	-3.1	-2.2	-2.5	0.3	-0.6	-0.6	-1.4	-2.9	-0.5	-1.3
Comparative body size at age 10	3.1	8.5	15.4	-3.2	-3.1	-3.9	-2.7	-3.4	-2.5	-3.1	-3.7	-3.4	-3.0	-2.8	-2.6	-3.8	-3.6	-3.5	-2.7	-2.8	-0.6	-2.5	-2.5	-2.7	-3.3	-1.0	-2.3
Alcohol intake versus 10 years previously	3.0	4.6	10.8	2.8	2.1	3.2	1.9	3.1	1.8	1.9	2.9	3.3	1.7	1.9	1.9	3.0	2.1	3.0	1.9	1.8	0.1	1.6	1.2	1.1	2.6	0.8	0.8
Qualifications: A levels/AS levels or equivalent	3.0	6.7	14.7	-2.3	-3.7	-3.1	-3.8	-2.1	-2.8	-1.7	-2.5	-1.9	-2.5	-2.5	-2.8	-1.8	-2.4	-2.5	-3.0	-3.4	-1.9	-1.9	-3.3	-2.5	-3.2	-2.7	-1.0
Medication: Lisinopril	3.0	3.9	10.5	1.7	2.4	1.7	1.6	1.6	2.4	3.2	1.7	1.6	2.1	1.5	2.4	2.0	2.2	1.7	2.2	2.4	2.0	2.6	1.5	1.9	2.0	1.5	1.3
Verbal and Numeric Reasoning (VNR)	2.9	6.9	13.5	-1.5	-3.7	-2.3	-3.3	-1.3	-3.3	-3.1	-1.1	-1.0	-2.6	-3.1	-3.1	-1.7	-2.8	-1.3	-2.9	-3.3	-2.7	-3.2	-3.5	-2.9	-2.4	-2.7	-2.7
Bipolar Disorder (2011)	2.9	2.8	10.2	2.3	1.8	2.6	1.9	2.2	1.2	1.4	3.2	2.2	1.5	1.2	1.3	2.3	1.7	2.3	1.2	1.0	-0.2	1.1	1.2	0.8	1.9	0.5	0.9
Neuroticism (2016)	2.9	4.2	9.0	-2.6	-1.9	-2.3	-1.0	-2.8	-2.2	-2.7	-2.7	-2.8	-1.5	-1.3	-2.3	-3.0	-2.2	-2.5	-2.3	-2.1	-0.3	-2.0	-0.5	-1.6	-2.3	-0.7	-1.4
Diabetes diagnosed by doctor	2.9	4.7	8.1	-2.4	-2.8	-2.2	-2.5	-2.4	-2.5	-1.9	-2.4	-1.9	-1.9	-2.2	-2.5	-2.2	-2.0	-2.2	-2.6	-2.3	-0.7	-2.1	-2.5	-1.6	-2.5	-1.8	-2.0
Blood White Count	2.8	21.1	51.6	-6.2	-3.0	-4.2	1.1	-5.9	-5.5	-5.2	-5.2	-7.2	-1.8	-4.3	-5.7	-7.1	-4.6	-5.4	-5.4	-4.4	1.0	-4.5	0.4	-2.6	-5.1	1.4	-5.4
Lung FEV1/FVC ratio	2.8	14.4	23.4	-4.5	-4.0	-4.1	-2.7	-4.2	-4.2	-3.5	-4.3	-4.2	-2.9	-4.0	-4.4	-4.6	-4.5	-4.6	-4.5	-4.2	-1.6	-3.3	-3.2	-3.4	-4.8	-2.3	-2.8
Maternal smoking around birth	2.8	4.0	7.2	2.1	2.6	2.2	2.1	2.0	2.2	1.3	2.0	2.0	2.3	1.9	2.3	1.8	2.0	2.2	2.5	2.7	1.0	1.6	2.2	1.8	2.7	1.2	1.0
Diabetes (self-reported)	2.8	4.3	7.7	-2.4	-2.8	-2.3	-2.3	-2.4	-2.5	-1.9	-2.0	-2.0	-1.4	-2.1	-2.6	-2.1	-1.9	-2.2	-2.5	-2.3	-0.6	-1.9	-2.2	-1.4	-2.4	-1.4	-1.9
Chronic bronchitis/emphysema (mother)	2.8	3.3	9.2	2.7	1.6	1.6	0.1	2.7	2.2	1.5	2.2	3.0	0.7	1.2	2.3	2.8	1.3	2.2	2.4	1.9	-0.7	1.7	0.1	0.7	2.0	-1.0	1.1
Smoking status: Previous	2.8	4.2	8.7	2.4	2.5	2.9	2.6	2.5	1.8	1.4	2.1	2.3	1.2	2.0	1.9	2.3	2.5	3.0	2.1	2.0	0.8	1.0	2.1	1.8	2.8	1.8	0.4
Forced expiratory volume in 1-second (FEV1)	2.7	9.2	14.7	-2.1	-3.7	-2.6	-2.8	-1.8	-3.8	-3.8	-1.8	-1.6	-3.1	-3.1	-3.7	-2.3	-3.3	-2.0	-3.5	-3.6	-3.5	-3.7	-3.4	-3.4	-3.0	-3.7	-2.9
Medication: Blood pressure	2.7	4.7	8.1	2.5	2.4	2.1	1.0	2.7	2.8	2.8	2.4	2.6	2.0	1.4	2.9	2.7	2.2	2.3	2.6	2.6	1.0	2.2	1.3	1.8	2.6	1.3	1.1
Average weekly red wine intake	2.7	3.9	9.1	3.0	1.4	1.6	-0.6	2.8	2.5	1.9	2.2	2.7	0.8	2.0	2.6	2.8	1.7	2.4	2.6	2.0	-0.8	1.4	0.8	1.0	2.3	0.2	2.5
Mood swings	2.7	4.9	8.8	-2.6	-2.3	-2.4	-1.2	-2.5	-2.7	-3.0	-2.0	-2.5	-1.4	-1.9	-2.7	-2.8	-2.1	-2.4	-2.9	-2.6	-0.7	-2.4	-1.5	-1.9	-2.5	-0.7	-2.4
Guilty feelings	2.7	4.1	9.1	-3.0	-2.1	-2.4	-0.9	-2.7	-2.4	-1.7	-2.5	-2.6	-0.8	-1.4	-2.5	-2.6	-1.8	-2.7	-2.7	-2.4	-0.1	-1.5	-1.1	-1.1	-2.6	-0.7	-1.0
Happiness	2.6	3.1	7.6	-0.9	-2.5	-1.5	-2.8	-0.6	-1.8	-2.1	-0.8	-0.3	-1.8	-1.8	-1.8	-1.3	-2.0	-0.9	-1.8	-1.9	-2.0	-1.5	-2.6	-2.6	-1.5	-2.1	-1.9
Headache pain in last month	2.6	4.4	10.0	-1.8	-3.0	-1.8	-2.1	-1.5	-2.9	-1.0	-1.1	-1.0	-1.5	-2.5	-2.9	-1.3	-2.0	-1.9	-2.9	-3.2	-1.4	-1.1	-2.8	-2.2	-2.8	-2.6	-1.1
Intelligence (Savage-Jansen 2018)	2.5	7.7	14.2	-2.3	-3.7	-2.5	-3.3	-2.0	-3.3	-2.5	-2.3	-1.4	-2.5	-2.9	-3.3	-2.0	-2.8	-2.4	-3.2	-3.6	-2.4	-2.4	-3.8	-2.9	-3.3	-3.3	-2.2
Medication: Metformin	2.5	3.5	6.1	-1.8	-2.4	-1.7	-1.9	-1.5	-2.4	-1.8	-1.8	-1.3	-1.7	-1.9	-2.4	-1.7	-1.7	-1.6	-2.5	-2.4	-1.1	-2.0	-2.4	-1.6	-2.1	-1.7	-1.4
Sensitivity / hurt feelings	2.4	4.2	10.6	-3.3	-1.9	-2.3	-0.9	-3.2	-2.2	-1.7	-2.8	-3.1	-0.4	-1.5	-2.3	-2.7	-1.7	-2.9	-2.6	-2.1	0.9	-0.7	-0.8	-0.8	-2.6	-0.2	-1.1
Waist circumference	2.4	8.7	15.5	3.1	3.3	2.4	1.7	2.9	3.7	3.6	1.8	2.6	1.9	3.2	3.7	2.8	3.5	3.1	3.9	3.9	2.3	2.2	2.5	3.0	3.8	3.3	2.5
Number of incorrect matches in round	2.4	3.9	6.3	-1.5	-1.9	-1.5	-0.9	-1.0	-2.4	-2.3	-1.6	-1.0	-2.4	-2.4	-2.4	-1.8	-2.1	-1.7	-2.4	-2.4	-2.1	-2.5	-1.9	-2.1	-2.2	-2.1	-2.5
Pack years of smoking	2.4	3.5	9.8	0.9	2.7	1.7	3.1	0.7	1.9	1.6	1.0	0.3	1.6	1.6	1.9	0.7	1.7	1.1	2.0	2.3	2.9	1.6	2.6	2.0	1.9	3.1	0.6
Crohns Disease (2012)	2.3	3.7	6.6	2.3	2.3	1.5	1.2	2.0	2.5	1.6	2.0	1.7	1.4	2.4	2.5	1.8	1.9	2.1	2.6	2.4	0.4	1.3	2.1	1.6	2.4	1.4	2.2
LDL Cholesterol	2.3	3.6	6.4	-2.2	-2.2	-2.2	-1.9	-2.4	-1.9	-1.7	-2.0	-2.2	-1.8	-1.8	-1.9	-1.9	-1.9	-2.5	-2.0	-2.1	-0.4	-1.0	-1.9	-1.8	-2.5	-1.4	-1.1
Age when periods started (menarche)	2.3	5.5	11.2	3.3	1.8	2.1	0.3	3.2	2.6	2.0	3.1	3.3	0.9	2.5	2.8	2.7	2.4	3.1	3.0	2.7	-0.2	1.4	1.4	1.4	3.0	0.5	2.5
Hayfever/allergic rhinitis (self-reported)	2.3	3.0	6.6	2.1	1.6	1.5	0.0	1.6	2.6	2.0	1.8	2.0	0.9	1.6	2.6	2.5	1.8	1.7	2.4	2.1	0.3	1.9	0.7	1.5	2.1	-0.1	1.6
Ever had stillbirth, spontaneous miscarriage or termination	2.3	2.5	6.2	-0.6	-1.9	-1.1	-1.2	-0.2	-2.1	-2.2	-0.3	-0.4	-1.8	-1.6	-2.0	-1.2	-1.8	-0.5	-1.6	-1.8	-2.0	-2.5	-1.6	-2.1	-1.2	-1.4	-2.2
Ever smoked	2.2	3.9	6.9	2.2	2.2	2.3	1.5	2.2	2.2	1.9	1.7	2.1	1.3	2.2	2.3	2.4	2.3	2.6	2.3	2.1	1.1	1.9	1.6	1.7	2.6	1.5	1.5
Body Mass Index (BMI) (2010)	2.1	2.9	7.8	1.2	1.7	1.5	1.2	0.9	1.7	2.5	1.6	1.4	2.8	1.2	1.7	1.8	1.9	1.5	1.5	1.8	1.8	2.2	0.9	1.7	1.8	2.2	1.8
Severe depression (siblings)	2.1	2.4	5.2	-1.1	-1.7	-1.4	-1.6	-1.0	-1.4	-2.0	-1.0	-0.8	-1.8	-1.3	-1.4	-1.6	-1.9	-1.3	-1.6	-1.8	-1.8	-1.6	-1.7	-2.0	-1.7	-2.3	-1.0
Had other major operations	2.1	2.5	12.3	-1.9	-0.9	-1.2	0.6	-1.4	-1.9	-1.7	-1.2	-1.4	-1.2	-2.0	-1.9	-1.7	-1.5	-1.5	-2.2	-2.0	-0.2	-1.6	-1.2	-1.2	-1.7	-0.3	-3.5
Medication: Paracetamol	2.1	3.4	13.5	2.9	1.2	2.6	1.2	3.2	0.6	1.4	3.7	3.4	1.4	0.6	0.9	2.7	1.3	3.0	1.2	0.8	-1.2	0.8	0.2	0.4	2.1	-0.4	0.4
Number of children fathered	2.1	2.4	7.5	0.4	1.8	1.6	1.7	0.3	1.7	2.0	0.3	0.5	2.7	1.5	1.6	1.4	1.3	0.4	1.3	1.4	1.7	2.7	1.6	2.0	0.9	1.3	2.1
Had major operations	2.1	2.5	5.5	-2.4	-1.7	-2.2	-1.0	-2.3	-1.9	-0.7	-1.9	-2.1	0.1	-1.2	-2.0	-1.8	-1.3	-2.3	-1.9	-1.9	0.0	-0.8	-0.9	-0.7	-2.3	-0.3	0.2
BMI	2.0	11.5	23.7	3.2	3.6	2.9	2.4	2.9	3.7	4.9	2.2	2.9	3.3	3.7	3.8	3.6	4.0	3.2	4.0	3.9	3.1	3.6	2.7	3.8	3.7	3.5	3.6
Knee pain experienced in last month	2.0	3.1	7.8	1.8	2.4	2.2	2.8	2.0	1.4	1.5	2.2	1.7	2.0	1.3	1.4	1.6	1.7	2.1	1.7	1.8	0.8	1.0	1.7	1.5	2.1	2.4	-0.2
Illnesses of siblings: Diabetes	2.0	2.5	4.0	-1.2	-1.7	-1.4	-1.3	-1.1	-1.7	-1.6	-1.6	-1.1	-2.0	-1.8	-1.7	-1.6	-1.8	-1.2	-1.8	-2.0	-1.3	-1.8	-1.9	-1.7	-1.7	-1.4	-1.8
Heart disease (siblings)	2.0	2.5	5.6	2.2	1.4	1.2	0.1	2.0	2.1	1.2	1.8	1.9	0.6	1.7	2.2	1.7	1.7	2.0	2.4	2.2	-0.1	1.0	1.2	1.1	2.3	0.7	0.6
Alzheimer’s Disease (including proxy)	1.9	2.8	5.2	-2.2	-1.5	-1.6	-0.0	-1.8	-2.2	-2.0	-1.6	-1.9	-0.8	-1.4	-2.3	-2.3	-1.8	-2.0	-2.3	-2.0	-0.4	-1.5	-0.3	-1.2	-2.2	-1.1	-1.1
Mean Putamen Volume	1.9	2.1	3.4	-1.8	-1.7	-1.5	-1.2	-1.4	-1.6	-1.4	-1.3	-1.4	-1.4	-1.7	-1.7	-1.6	-1.3	-1.4	-1.7	-1.5	-1.0	-1.8	-1.3	-1.1	-1.5	-1.0	-1.8
Type 2 Diabetes (T2D) (2018)	1.9	3.6	7.0	-1.9	-2.6	-2.0	-2.3	-2.0	-2.3	-1.4	-1.8	-1.7	-1.9	-1.8	-2.3	-1.6	-1.7	-1.9	-2.3	-2.1	-0.7	-1.6	-2.5	-1.6	-2.2	-1.8	-1.6
Qualifications: O levels/GCSEs or equivalent	1.9	3.0	14.7	-1.5	-2.7	-2.6	-3.8	-1.8	-1.0	-0.6	-1.9	-1.3	-1.8	-0.6	-1.1	-0.7	-1.1	-1.9	-1.5	-1.8	-0.6	-0.2	-2.5	-1.5	-2.0	-2.4	0.7
Average weekly beer plus cider intake	1.9	2.7	7.6	1.7	2.5	2.4	2.8	1.9	1.7	0.5	1.8	1.6	1.5	0.9	1.7	0.8	1.2	1.9	1.6	2.0	0.7	0.4	2.5	1.3	2.3	1.4	-0.5
Primary Biliary Cirrhosis	1.8	2.5	4.2	1.4	1.8	1.6	1.4	1.4	1.6	1.5	1.9	1.1	1.6	2.0	1.6	1.4	1.8	1.4	1.8	1.9	1.2	1.7	2.0	1.4	1.7	1.4	1.7
Qualifications: CSEs or equivalent	1.8	2.4	5.3	1.1	2.1	1.0	1.7	0.7	1.8	1.7	1.0	0.8	1.6	2.3	1.8	1.2	1.5	0.7	1.8	2.1	1.3	2.1	1.8	1.6	1.5	0.9	2.2
Health satisfaction	1.8	2.4	4.8	1.6	1.4	1.5	0.8	1.7	1.5	1.7	1.4	1.9	2.0	1.6	1.5	2.2	1.7	1.6	1.7	1.7	1.1	2.1	0.8	1.2	1.7	1.1	1.4
Alcohol drinker status: Never	1.8	2.2	5.2	-2.3	-1.6	-1.6	-0.5	-2.0	-2.0	-0.9	-1.6	-2.1	-1.2	-1.2	-2.1	-1.6	-1.1	-1.9	-1.9	-1.6	0.3	-1.0	-0.9	-0.8	-1.9	-0.6	-0.8
Taking other prescription medications	1.7	2.7	7.5	-1.5	-1.4	-0.8	-0.2	-1.2	-2.2	-2.2	-0.8	-1.2	-1.3	-2.1	-2.1	-1.6	-1.9	-1.3	-2.2	-2.2	-1.0	-1.9	-1.2	-1.7	-1.7	-1.4	-2.7
Stomach or abdominal pain in last month	1.7	2.1	7.8	-1.0	-1.3	0.2	0.8	-0.3	-2.8	-1.4	0.5	-0.2	-0.4	-1.3	-2.6	-0.8	-1.1	-0.4	-2.6	-2.4	-1.6	-1.7	-0.9	-1.4	-1.4	-1.6	-1.9
Pulse wave reflection index	1.7	2.1	4.1	-1.7	-1.7	-2.0	-1.7	-1.6	-1.2	-1.1	-1.2	-1.6	-1.4	-1.5	-1.3	-1.4	-1.5	-1.9	-1.6	-1.6	-0.6	-1.0	-1.4	-1.1	-1.9	-1.4	-1.0
Glaucoma (self-reported)	1.7	2.0	4.9	2.2	1.4	1.6	1.0	2.1	1.3	0.8	2.2	1.7	0.9	1.0	1.4	1.6	1.1	2.0	1.6	1.4	-0.4	0.5	1.4	0.5	1.8	1.1	1.1
Medication: Blood pressure	1.7	3.3	7.4	1.8	1.9	1.8	0.9	1.6	2.4	2.7	1.2	1.8	1.3	1.3	2.4	2.2	2.3	1.8	2.0	2.0	1.7	2.2	1.0	1.9	2.0	1.1	1.4
Crohns Disease (2017)	1.6	3.4	6.0	2.2	2.1	1.6	1.5	2.0	2.0	1.3	1.9	1.8	2.1	2.2	2.0	2.0	1.8	2.3	2.2	2.2	0.5	1.4	1.9	1.6	2.4	1.9	1.5
Blood Platelet Count	1.6	18.1	88.5	0.4	5.2	1.6	6.0	-0.3	3.8	2.8	0.8	-2.1	5.0	4.8	3.5	-0.4	3.5	0.9	4.0	4.8	6.3	2.9	8.1	5.2	3.1	9.4	2.9
High blood pressure (mother)	1.6	2.3	5.7	1.7	1.3	1.1	0.4	1.6	1.7	2.4	2.0	1.8	1.0	1.6	1.8	1.9	1.8	1.5	1.6	1.5	0.7	1.6	0.4	1.2	1.6	0.8	2.2
Medication: Lansoprazole	1.6	1.9	7.0	-1.2	-1.3	-0.9	-0.4	-0.7	-1.9	-1.6	-0.6	-0.8	-0.9	-2.1	-1.9	-1.1	-1.4	-0.7	-1.9	-1.7	-0.8	-1.8	-1.3	-1.3	-1.1	-0.7	-2.6
Eye problems/disorders: None of the above	1.6	1.8	3.1	-1.3	-1.8	-1.6	-1.7	-0.9	-1.5	-1.3	-1.0	-0.9	-1.3	-1.1	-1.6	-1.2	-1.1	-1.2	-1.6	-1.7	-1.5	-1.7	-1.3	-1.0	-1.6	-1.5	-1.1
Coronary Artery Disease (CAD)	1.5	1.7	3.6	1.4	1.7	1.2	0.6	0.6	1.9	1.6	1.4	1.5	1.0	1.2	1.9	1.5	1.1	1.0	1.8	1.7	0.4	1.6	0.5	1.3	1.3	0.5	1.7
Fasting Glucose	1.5	1.7	3.2	1.1	1.6	1.6	1.8	1.3	1.1	1.5	1.6	1.4	1.5	1.2	1.1	1.4	1.6	1.4	1.2	1.2	1.0	1.3	1.3	1.5	1.3	1.2	0.7
Noisy workplace	1.5	1.8	4.9	1.2	2.2	1.1	1.9	1.0	1.9	0.6	0.9	0.7	1.5	1.2	1.9	0.8	1.0	0.9	1.9	1.9	0.6	1.1	2.0	0.9	1.5	1.3	0.8
Alcohol intake frequency.	1.5	3.4	8.6	-2.6	-1.7	-2.2	-0.8	-2.6	-1.9	-1.2	-2.3	-2.5	-0.6	-1.8	-2.0	-2.4	-2.4	-2.9	-1.9	-2.0	0.3	-0.7	-0.9	-1.3	-2.7	-0.4	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.5	1.7	3.5	1.7	1.2	1.6	0.8	1.5	1.1	0.8	1.7	1.7	1.6	1.4	1.2	1.9	1.3	1.7	1.4	1.3	-0.1	1.4	1.2	1.0	1.6	0.1	1.0
Mother’s age at death	1.5	1.9	4.5	-1.5	-2.0	-1.0	-1.2	-1.1	-2.1	-1.1	-0.7	-1.0	-0.3	-1.4	-2.1	-0.9	-1.3	-1.3	-1.9	-2.1	-0.5	-0.5	-1.4	-1.0	-2.0	-1.7	-0.4
Rheumatoid Arthritis	1.4	1.9	5.5	0.7	1.7	0.7	1.3	0.5	1.7	1.2	0.5	0.3	0.9	1.6	1.7	0.5	1.5	0.8	1.7	2.0	2.0	1.2	1.7	1.8	1.4	2.3	1.1
Other serious medical condition/disability diagnosed by doctor	1.4	1.8	4.6	-2.1	-0.7	-0.6	1.2	-1.7	-1.9	-0.5	-1.9	-1.9	-0.2	-1.4	-1.9	-1.4	-1.1	-1.9	-1.8	-1.6	0.5	-0.6	-0.1	-0.4	-1.9	-0.0	-1.4
Mouth/teeth dental problems	1.4	2.1	3.4	-1.5	-1.8	-1.2	-1.3	-1.6	-1.7	-1.3	-1.7	-1.6	-1.3	-1.4	-1.7	-1.6	-1.4	-1.8	-1.7	-1.6	-0.7	-1.1	-1.1	-1.4	-1.9	-1.6	-0.6
Illnesses of mother	1.4	1.8	5.0	-1.5	-1.0	-0.7	0.1	-1.4	-1.6	-2.2	-1.4	-1.7	-1.1	-0.9	-1.6	-1.9	-1.1	-1.1	-1.6	-1.4	-0.7	-2.1	0.1	-0.9	-1.1	-0.3	-2.0
Illness, injury, bereavement, stress in last 2 years	1.4	1.7	5.0	1.7	1.2	2.1	1.9	1.7	0.4	0.7	2.2	1.8	1.3	0.8	0.5	1.9	1.4	1.9	0.8	0.7	-0.0	0.7	0.8	0.8	1.5	0.7	-0.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.4	1.6	9.9	0.3	-0.7	0.6	0.4	0.7	-1.7	-1.9	1.4	0.6	-0.8	-1.8	-1.5	-0.5	-1.1	0.9	-0.9	-1.0	-1.5	-2.1	-0.6	-1.3	0.1	-0.6	-3.1
Handedness (chirality/laterality): Left-handed	1.4	1.6	3.7	1.0	1.5	0.8	1.0	0.9	1.5	1.8	1.2	0.4	0.6	1.6	1.5	1.0	1.8	1.0	1.3	1.6	1.1	1.2	1.6	1.4	1.3	1.2	1.9
Qualifications: nursing, teaching	1.4	2.2	5.1	-1.5	-2.0	-1.9	-2.1	-1.3	-1.5	-0.5	-1.1	-1.2	-1.0	-1.5	-1.6	-0.7	-1.3	-1.8	-1.8	-2.0	-0.7	-0.4	-2.0	-1.2	-2.1	-2.3	-0.1
Supplements: Glucosamine	1.3	1.7	3.9	-1.9	-1.2	-1.3	0.2	-1.8	-1.9	-1.2	-1.9	-1.8	-0.5	-0.9	-2.0	-1.5	-0.8	-1.5	-1.8	-1.6	0.6	-1.1	-0.8	-0.3	-1.6	0.2	-0.5
Length of working week for main job	1.3	1.4	3.6	-1.1	-1.6	-0.9	-0.7	-0.9	-1.9	-1.0	-0.7	-0.9	-1.1	-1.2	-1.9	-1.0	-0.9	-1.0	-1.7	-1.7	-0.4	-1.1	-1.2	-1.2	-1.4	-0.8	-1.1
Comparative height size at age 10	1.3	7.4	16.4	-3.9	-2.5	-1.7	0.4	-3.4	-4.0	-2.9	-2.9	-3.7	-0.6	-2.5	-4.0	-3.8	-2.4	-3.0	-3.8	-3.1	0.3	-3.0	-0.8	-1.4	-3.1	0.2	-2.1
Chest pain or discomfort	1.3	1.8	4.8	0.7	1.4	2.2	2.1	1.1	0.5	1.9	1.5	1.4	2.0	1.2	0.6	1.7	1.8	1.1	0.7	0.8	1.0	1.4	1.2	1.6	1.1	0.2	1.2
Back pain experienced in last month	1.3	1.9	5.7	-0.6	-1.6	0.2	-0.3	0.0	-2.4	-1.3	0.0	0.2	-0.9	-1.8	-2.2	-0.3	-1.2	-0.2	-2.0	-2.2	-1.5	-1.6	-1.8	-1.5	-1.3	-2.0	-1.4
Medication: Omeprazole (e.g. Zanprol)	1.3	1.6	7.2	-0.2	-0.7	0.2	0.8	0.2	-1.8	-2.1	0.5	-0.1	-0.4	-1.9	-1.7	-0.9	-1.5	0.0	-1.3	-1.5	-1.4	-2.1	-0.3	-1.5	-0.7	-0.5	-2.7
Ulcerative Colitis (UC)	1.2	2.2	7.6	0.7	-1.1	0.0	-0.7	1.2	-1.6	-2.1	1.3	1.2	-1.4	-1.7	-1.4	0.2	-1.1	1.0	-1.0	-1.1	-2.8	-2.3	-1.7	-1.9	0.0	-2.1	-2.6
Hand grip strength (left)	1.2	3.2	7.8	-0.9	-1.6	-1.1	-1.1	-0.6	-1.7	-2.5	-0.7	-0.5	-2.2	-2.2	-1.6	-1.5	-2.2	-1.1	-1.8	-1.9	-2.8	-2.4	-1.9	-2.4	-1.7	-2.8	-2.1
Weight	1.2	5.7	11.9	1.7	2.6	2.0	2.0	1.5	2.6	3.0	0.9	1.3	2.3	2.7	2.6	1.9	2.9	2.0	2.8	3.0	2.9	1.9	2.3	3.0	2.8	3.5	2.3
Breastfed as a baby	1.2	1.5	4.2	-1.5	-1.6	-2.0	-1.8	-1.8	-0.8	-0.4	-1.6	-1.8	-0.7	-0.4	-0.9	-1.4	-0.9	-1.6	-1.3	-1.1	-0.0	-0.4	-0.7	-0.9	-1.5	-0.7	0.6
Medication: Amlodipine	1.2	1.7	3.5	1.3	1.9	1.3	1.8	1.4	1.5	1.0	1.1	0.9	1.4	0.9	1.6	1.2	1.3	1.4	1.3	1.4	0.7	0.6	1.8	1.2	1.7	1.8	-0.1
Osteoarthritis (self-reported)	1.2	1.5	5.6	1.6	1.3	1.9	2.4	1.8	0.1	0.3	2.2	1.5	1.2	0.2	0.3	1.2	0.9	2.0	0.8	0.5	-0.2	-0.3	1.1	0.9	1.3	1.3	-0.3
Pain type(s) experienced in last month: Hip pain	1.2	1.5	4.8	0.4	1.4	0.9	1.7	0.5	1.0	1.3	0.4	0.4	2.2	1.3	1.0	0.9	1.1	0.2	1.1	1.1	1.4	1.8	1.5	1.7	0.6	1.6	1.6
Age started oral contraceptive pill	1.2	1.5	3.0	1.7	1.3	1.2	0.7	1.6	1.4	0.9	1.5	1.7	0.6	0.5	1.5	1.1	1.1	1.7	1.7	1.6	0.4	0.6	0.4	1.0	1.7	1.7	-0.4
Myopia	1.2	1.7	6.0	-0.2	-1.7	-0.8	-1.8	-0.1	-1.4	-1.5	-0.3	-0.1	-1.5	-1.0	-1.3	-0.6	-1.2	-0.4	-1.2	-1.8	-2.4	-1.7	-1.4	-1.6	-1.1	-2.1	-0.5
Pain experienced in last month	1.2	2.0	5.7	0.9	1.4	0.0	-0.2	0.4	2.4	1.1	0.2	0.4	0.5	2.0	2.3	0.5	1.2	0.7	2.3	2.4	1.2	1.3	1.6	1.6	1.7	1.7	1.9
Qualifications: None of the above	1.1	2.2	10.7	0.1	2.2	1.7	3.2	0.2	1.0	0.4	0.4	-0.0	1.6	0.7	0.9	-0.2	0.9	0.6	1.1	1.7	2.5	0.6	2.2	1.9	1.3	3.3	-0.7
Fluid intelligence score	1.1	2.2	5.4	-1.2	-2.3	-1.4	-1.9	-1.0	-2.2	-1.1	-0.7	-0.9	-0.7	-1.9	-2.1	-0.8	-1.2	-0.8	-2.0	-2.2	-1.0	-1.6	-1.9	-1.3	-1.6	-1.2	-1.2
Mouth/teeth dental problems: Dentures	1.1	1.8	8.1	0.5	1.6	1.0	1.8	0.6	1.2	1.3	1.1	0.4	1.5	1.2	1.1	0.5	1.3	0.9	1.2	1.4	2.1	1.0	1.7	1.9	1.3	2.9	0.4
Age at first live birth	1.1	2.0	7.6	-1.8	-1.8	-2.7	-2.8	-1.9	-0.5	0.3	-2.1	-1.8	-0.4	-0.5	-0.6	-1.2	-1.0	-2.1	-1.1	-1.1	0.6	0.4	-1.4	-0.5	-1.8	-0.4	1.0
Pulse wave peak to peak time	1.1	1.3	4.8	-1.9	-0.6	-1.4	-0.4	-2.2	-0.7	-0.3	-1.5	-2.2	0.3	-0.3	-0.8	-1.6	-0.7	-1.8	-1.3	-0.9	1.1	0.1	-0.1	-0.1	-1.4	0.5	0.8
Age at last live birth	1.1	1.6	5.2	-1.9	-1.4	-1.9	-1.4	-1.9	-0.8	0.2	-2.3	-1.9	-0.7	-0.1	-0.9	-1.4	-0.7	-2.0	-1.0	-0.9	1.0	0.1	-0.5	-0.0	-1.8	-0.0	1.1
Ovarian Cancer	1.0	1.4	5.9	-0.5	1.0	-0.3	0.4	-0.9	1.4	1.3	-0.9	-1.0	0.7	1.4	1.3	0.1	1.0	-0.6	1.2	1.7	2.4	1.8	1.2	1.6	0.4	1.4	1.3
Hearing difficulty/problems: Yes	1.0	1.6	5.3	-2.2	0.2	-0.6	1.5	-1.8	-0.8	-1.5	-1.5	-2.0	-0.2	-1.0	-1.0	-2.3	-1.1	-1.6	-1.2	-0.7	1.2	-1.0	0.6	0.1	-1.1	1.0	-1.3
Chronic bronchitis/emphysema (father)	1.0	1.2	2.1	1.1	1.4	1.4	1.2	1.0	1.2	0.5	0.8	1.0	0.6	1.3	1.2	1.3	1.2	1.2	1.4	1.4	0.7	1.2	1.1	1.0	1.3	0.8	0.0
Hip circumference	1.0	4.4	7.6	1.9	2.3	1.9	1.5	1.8	2.5	2.6	1.0	1.5	1.6	2.4	2.5	1.9	2.5	2.0	2.7	2.8	2.1	1.5	1.9	2.4	2.6	2.6	2.0
Hair/balding pattern: Pattern 3	1.0	1.4	3.4	-1.3	-1.3	-1.8	-1.3	-1.6	-0.8	-1.6	-1.5	-1.7	-1.0	-1.0	-0.9	-1.7	-1.1	-1.4	-1.0	-0.8	-0.1	-0.9	-0.8	-1.1	-1.2	0.1	-1.3
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.2	3.5	0.3	-1.5	-0.8	-1.4	0.4	-1.4	-0.6	0.5	0.4	-1.3	-1.3	-1.2	0.1	-1.0	0.1	-1.0	-1.4	-1.7	-1.0	-1.5	-1.7	-0.8	-1.9	-1.1
Pulse wave Arterial Stiffness index	1.0	1.2	4.6	1.8	0.5	1.5	0.4	2.2	0.5	0.0	1.5	2.2	-0.4	0.3	0.7	1.5	0.7	1.8	1.2	0.8	-1.1	-0.3	0.0	0.0	1.3	-0.5	-1.0
Shortness of breath walking on level ground	1.0	1.2	4.1	1.5	1.0	1.3	0.4	1.8	1.0	0.8	1.3	2.0	1.1	0.6	1.1	1.5	1.1	1.4	1.3	1.2	-0.2	1.0	0.2	0.4	1.3	-0.5	0.3
Family relationship satisfaction	1.0	1.3	4.2	-0.2	-1.6	-0.2	-1.4	0.3	-1.4	-0.8	0.2	0.6	-1.2	-1.3	-1.3	-0.3	-1.0	-0.0	-1.3	-1.4	-1.3	-0.9	-2.0	-1.6	-0.8	-1.8	-0.6
Triglycerides	0.9	1.4	3.2	1.1	1.3	1.2	1.3	1.1	1.1	1.8	1.4	1.1	1.3	1.0	1.2	1.4	1.7	1.3	1.1	1.0	0.8	1.2	1.0	1.1	1.2	1.0	1.1
Height	0.9	17.6	41.9	-4.6	-4.5	-2.7	-1.4	-3.9	-6.0	-6.5	-3.1	-4.2	-2.9	-4.3	-6.0	-5.4	-4.6	-3.4	-5.3	-4.8	-1.8	-5.6	-2.5	-3.8	-4.1	-1.0	-4.4
Lung FVC	0.9	4.5	15.5	3.4	1.1	1.7	-0.6	3.6	1.9	1.2	2.9	3.9	0.1	1.3	2.1	3.4	1.4	3.1	2.2	1.3	-2.5	0.7	-0.4	0.2	2.3	-1.7	1.2
Impedance of leg (right)	0.9	4.3	14.5	3.7	1.2	2.9	0.8	3.8	1.0	-0.2	3.8	3.7	0.2	0.6	1.3	2.6	0.9	3.5	1.9	1.3	-2.2	-0.1	0.6	-0.3	2.5	-0.7	-0.6
Sitting height	0.9	6.5	13.5	-3.1	-3.0	-1.9	-1.2	-2.9	-3.7	-3.2	-2.6	-2.9	-1.9	-2.0	-3.7	-3.1	-2.2	-2.3	-3.4	-3.0	-0.6	-3.0	-1.7	-1.8	-2.8	-1.3	-2.1
Impedance of leg (left)	0.9	4.3	14.2	3.8	1.2	2.8	0.7	3.8	1.1	-0.3	3.7	3.8	-0.1	0.6	1.4	2.5	0.7	3.5	1.9	1.2	-2.6	-0.3	0.6	-0.4	2.5	-1.0	-0.4
Nervous feelings	0.9	1.8	3.3	-1.6	-1.1	-1.3	-0.3	-1.2	-1.6	-1.6	-1.0	-1.2	-1.3	-1.6	-1.6	-1.7	-1.6	-1.4	-1.8	-1.6	-0.1	-1.4	-1.1	-1.1	-1.5	-0.9	-1.4
Forced vital capacity (FVC)	0.9	3.4	8.9	-0.6	-2.3	-1.0	-1.8	-0.3	-2.3	-2.6	-0.3	-0.1	-2.1	-1.6	-2.2	-0.8	-1.8	-0.4	-1.9	-2.2	-3.0	-2.5	-2.1	-2.2	-1.4	-2.8	-1.9
Standing height	0.9	9.3	21.5	-3.7	-3.5	-2.1	-0.9	-3.3	-4.6	-4.2	-2.5	-3.5	-1.9	-2.7	-4.6	-3.9	-2.8	-2.7	-4.0	-3.5	-0.8	-4.0	-1.6	-2.3	-3.2	-0.7	-2.7
Medication: Omeprazole	0.9	1.0	6.8	0.1	-0.1	0.6	1.1	0.5	-1.2	-1.7	0.7	0.1	-0.3	-1.4	-1.1	-0.7	-1.0	0.4	-0.8	-0.8	-1.0	-1.9	0.2	-1.1	-0.1	-0.2	-2.6
Heart disease (mother)	0.9	1.1	2.9	1.2	1.3	0.4	0.4	1.1	1.5	0.8	0.5	1.1	0.5	0.4	1.5	0.8	0.7	1.3	1.6	1.7	1.0	0.9	0.2	0.6	1.6	1.5	-0.2
Pulse rate, automated reading	0.9	2.8	9.4	2.8	1.5	2.3	1.7	2.8	0.7	0.1	2.4	2.6	0.3	0.8	0.9	1.6	1.0	3.1	1.8	1.5	-0.8	-0.4	0.9	0.3	2.4	1.0	-1.1
Friendships satisfaction	0.9	1.2	2.7	-1.0	-1.7	-0.9	-1.4	-0.5	-1.5	-0.9	-0.5	-0.4	-0.7	-1.1	-1.4	-0.8	-1.3	-0.8	-1.4	-1.4	-0.8	-0.4	-1.3	-1.5	-1.3	-1.2	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.9	2.0	5.6	-0.4	-1.8	-0.9	-1.6	-0.1	-1.7	-1.9	0.2	-0.1	-1.8	-1.1	-1.6	-0.9	-1.6	-0.4	-1.4	-1.7	-2.4	-1.9	-1.6	-2.0	-1.1	-1.6	-1.3
Medication: Paracetamol	0.9	1.5	7.3	1.9	0.6	1.7	1.0	2.2	-0.1	0.6	2.7	2.2	0.9	0.3	0.1	1.6	0.7	2.0	0.6	0.4	-0.8	0.3	0.2	0.0	1.3	-0.4	0.1
Risk taking	0.9	1.3	5.3	-1.9	-0.0	-0.6	0.5	-2.1	-0.3	0.4	-2.3	-1.9	0.7	0.6	-0.4	-1.1	0.3	-1.4	-0.6	-0.1	2.2	0.8	0.6	1.2	-0.7	1.3	0.9
Alzheimer’s Disease (in mother)	0.8	0.9	3.1	-0.9	-1.1	-0.5	0.1	-0.6	-1.8	-0.9	-0.5	-0.5	-0.4	-0.9	-1.7	-0.7	-0.8	-0.9	-1.5	-1.4	-0.8	-0.7	-0.4	-0.9	-1.4	-1.3	-0.6
Alzheimer’s Disease (in father)	0.8	0.8	1.9	-1.1	-0.7	-0.5	0.3	-0.8	-1.3	-1.1	-0.8	-0.9	-0.2	-1.0	-1.4	-1.2	-1.1	-0.9	-1.4	-1.2	-0.3	-0.8	-0.1	-0.7	-1.1	-1.0	-0.9
Ulcerative Colitis	0.8	1.2	4.5	-0.4	-0.9	-0.3	-0.2	0.2	-1.5	-1.7	0.1	0.2	-1.1	-1.4	-1.4	-0.4	-1.0	-0.1	-1.3	-1.0	-1.4	-1.6	-1.3	-1.4	-0.6	-1.3	-2.1
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	3.2	-1.4	-0.7	-1.1	-0.5	-1.8	-0.7	-0.9	-0.7	-1.5	-0.2	-0.9	-0.8	-1.1	-1.0	-1.8	-0.8	-0.8	0.1	-0.1	-0.6	-0.4	-1.5	-0.7	0.0
Diabetes (mother)	0.8	1.0	2.8	-0.1	-1.2	-0.3	-0.6	-0.0	-1.5	-0.7	0.3	-0.0	-0.5	-1.3	-1.4	-0.1	-1.1	-0.3	-1.3	-1.7	-1.5	-1.0	-1.3	-1.4	-1.1	-1.5	-0.6
Loud music exposure frequency	0.8	0.9	2.3	0.6	1.2	0.9	1.2	0.8	0.8	0.8	0.6	0.7	1.0	1.5	0.8	0.7	1.1	0.7	1.0	1.1	0.5	0.8	1.4	1.1	0.9	0.8	1.5
Forced vital capacity (FVC), Best measure	0.8	3.1	6.6	-0.8	-2.4	-1.1	-1.9	-0.7	-2.2	-2.4	-0.4	-0.5	-2.0	-1.4	-2.2	-1.0	-1.7	-0.6	-1.9	-2.1	-2.5	-2.3	-2.1	-2.1	-1.4	-2.6	-1.4
Osteoporosis (self-reported)	0.8	1.0	3.3	1.0	0.9	1.4	0.8	1.1	0.7	1.6	0.9	1.4	1.8	0.8	0.8	1.5	1.0	0.9	0.8	0.6	0.2	1.5	0.4	1.0	0.8	0.1	1.0
Ever depressed for a whole week	0.8	1.0	2.7	-0.0	-1.1	-0.0	-0.4	0.5	-1.5	-1.1	0.6	0.7	-0.4	-1.3	-1.4	-0.1	-0.8	0.2	-1.3	-1.5	-1.6	-1.0	-1.3	-1.6	-0.6	-1.4	-1.0
Commuting to job workplace: Cycle	0.8	1.0	3.8	0.1	1.0	0.7	1.1	-0.1	0.9	1.1	0.2	-0.1	1.6	0.7	0.9	0.4	0.8	0.4	0.7	0.9	2.0	1.2	1.1	1.4	0.8	1.7	1.0
Impedance of whole body	0.8	4.2	15.6	3.4	0.4	2.3	0.1	3.7	0.2	-1.4	4.0	3.7	-0.7	-0.4	0.5	1.9	-0.1	3.2	1.1	0.5	-3.4	-1.3	-0.1	-1.3	2.1	-1.9	-1.5
Hair Pigment	0.7	19.1	51.1	3.5	5.6	2.5	4.5	2.9	4.9	4.8	1.8	1.9	6.2	4.4	4.9	3.3	4.8	3.6	5.0	5.5	4.0	3.8	4.7	5.0	5.1	7.2	2.9
Medication for hormone replacement therapy	0.7	0.8	3.2	-0.7	-0.8	-0.4	0.1	-0.1	-1.4	-1.3	-0.4	-0.1	0.1	-1.2	-1.4	-0.5	-0.9	-0.1	-1.2	-1.2	-0.8	-1.0	-0.8	-1.1	-0.6	-0.5	-1.8
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	2.4	0.2	-1.0	-0.2	-0.7	0.4	-1.0	-1.0	1.2	0.4	-0.9	-1.2	-0.8	0.1	-0.8	0.2	-0.9	-1.1	-1.6	-1.1	-0.9	-1.4	-0.4	-1.2	-1.4
Hair/balding pattern: Pattern 2	0.7	0.9	2.6	-1.3	-0.2	-1.0	0.3	-1.6	-0.4	0.9	-1.2	-1.6	1.2	0.0	-0.5	-0.6	0.1	-1.3	-0.7	-0.6	1.5	0.6	0.3	1.1	-0.9	1.3	1.2
Impedance of arm (right)	0.7	3.2	13.6	1.5	-1.1	0.6	-0.9	2.0	-1.4	-2.9	2.4	1.9	-1.5	-1.8	-1.1	0.1	-1.5	1.5	-0.6	-1.0	-3.7	-2.7	-1.0	-2.3	0.4	-2.4	-2.6
Number of live births	0.7	1.0	2.5	0.2	1.0	0.4	0.4	0.1	1.4	1.2	0.0	0.0	1.1	1.3	1.3	0.5	1.1	0.5	1.4	1.5	1.2	0.9	1.2	1.4	1.0	1.6	1.3
Impedance of arm (left)	0.7	3.2	13.6	2.3	-0.4	1.2	-0.5	2.7	-0.6	-2.2	3.2	2.7	-1.1	-1.4	-0.4	0.9	-0.9	2.1	0.2	-0.3	-3.7	-2.1	-0.7	-1.9	1.1	-2.4	-2.2
Worry too long after embarrassment	0.7	1.1	3.8	-1.9	-0.8	-1.2	-0.2	-1.8	-1.1	-0.7	-1.4	-1.7	0.8	-0.7	-1.2	-1.5	-0.6	-1.7	-1.3	-0.8	0.5	-0.4	0.1	0.1	-1.3	-0.0	-0.2
Overall health rating	0.7	1.4	3.8	1.1	1.5	1.6	2.0	1.3	0.7	0.8	1.0	1.2	1.9	1.1	0.8	1.0	1.0	1.2	1.1	1.0	1.0	1.1	1.5	0.9	1.1	1.6	0.4
Tinnitus: Yes, now most or all of the time	0.7	0.9	2.1	-0.6	-1.0	-0.4	-0.2	-0.4	-1.5	-1.2	-0.0	-0.3	-1.0	-1.0	-1.4	-0.6	-0.8	-0.3	-1.4	-1.4	-0.7	-1.1	-1.1	-1.3	-0.8	-0.8	-1.2
Medication: Atorvastatin	0.7	0.8	2.9	-1.7	-0.6	-1.1	-0.5	-1.6	-0.3	-0.0	-1.6	-1.3	-0.6	-0.1	-0.4	-0.9	-0.4	-1.4	-0.7	-0.5	1.6	0.5	-0.9	-0.1	-1.0	0.1	-0.2
Breast Cancer	0.6	1.3	4.4	-0.5	0.4	-0.5	-0.4	-1.1	1.2	1.1	-1.0	-1.3	1.0	1.6	1.0	-0.2	1.0	-0.6	1.1	1.4	2.1	1.3	1.4	1.6	0.4	1.7	1.9
HDL Cholesterol	0.6	1.0	2.8	-0.8	-0.7	-1.7	-1.7	-0.8	0.1	-1.3	-1.4	-0.9	-1.6	-0.6	0.1	-1.2	-1.6	-1.4	-0.2	-0.3	-0.9	-0.7	-0.9	-1.0	-0.8	-0.8	-0.2
Angina	0.6	0.8	3.4	-0.4	0.7	-0.1	0.5	-0.4	0.9	1.4	-0.7	-0.5	1.5	0.6	0.8	0.2	0.9	-0.4	0.6	1.1	1.8	1.4	0.8	1.1	0.3	1.3	1.1
Serious illness, injury or assault to yourself	0.6	0.7	2.0	-1.1	-0.8	-0.9	-0.7	-0.8	-0.6	0.3	-1.4	-0.7	0.0	-1.3	-0.6	-0.7	-1.1	-1.2	-1.1	-1.2	-0.2	-0.1	-0.7	-0.5	-1.4	-0.9	-0.1
Hearing difficulty/problems with background noise	0.6	0.9	2.7	-1.0	-0.3	0.1	0.8	-0.4	-1.1	-1.6	-1.0	-0.4	-1.4	-1.2	-1.1	-1.3	-1.2	-0.3	-1.1	-1.0	-0.5	-1.4	-0.4	-0.9	-0.7	-0.5	-1.6
Ever unenthusiastic/disinterested for a whole week	0.6	0.8	3.0	0.4	-1.2	-0.3	-0.9	0.7	-1.3	-1.0	0.4	0.8	-0.5	-0.5	-1.1	0.1	-0.5	0.4	-0.8	-1.2	-1.7	-1.0	-1.1	-1.3	-0.4	-0.9	-0.6
Gout (self-reported)	0.6	0.8	2.8	-0.1	0.9	-0.2	0.2	-0.4	1.3	0.6	-1.1	-0.6	0.4	1.5	1.2	-0.1	0.7	-0.2	1.0	1.5	1.7	1.0	1.1	0.9	0.7	1.4	0.8
Emphysema/chronic bronchitis	0.6	0.7	3.6	0.1	0.6	1.3	1.9	0.5	-0.4	0.5	1.3	0.5	1.3	0.6	-0.4	0.6	0.8	0.8	-0.0	0.2	0.8	0.4	1.2	0.9	0.6	0.9	0.3
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.4	-0.9	-0.5	-0.8	-0.2	-1.0	-0.7	-1.4	-1.1	-1.0	-0.5	-0.8	-0.8	-1.1	-0.8	-1.0	-0.8	-0.7	-0.0	-0.8	-0.2	-0.5	-0.8	-0.1	-1.5
Medication: Aspirin	0.6	0.8	3.9	-1.8	-0.1	-0.8	0.1	-1.6	0.0	0.2	-1.4	-1.4	0.6	-0.4	-0.1	-1.0	-0.2	-1.3	-0.7	-0.1	2.0	0.9	-0.0	0.3	-0.7	0.8	-0.2
Breast cancer (self-reported)	0.6	0.7	3.0	1.4	0.1	0.5	-0.3	1.5	0.2	-0.2	1.7	1.5	-0.1	-0.1	0.3	0.7	0.0	1.5	0.4	0.3	-1.2	-0.7	-0.3	-0.8	1.1	-0.1	-1.0
Medication: Aspirin	0.6	0.8	3.4	-1.9	-0.4	-0.8	0.0	-1.6	-0.4	-0.0	-1.4	-1.4	0.5	-0.6	-0.5	-1.1	-0.4	-1.3	-1.0	-0.4	1.7	0.5	-0.2	0.1	-0.9	0.5	-0.4
Hearing aid user	0.6	0.7	2.2	0.8	1.3	1.0	1.5	0.6	0.9	0.2	0.7	0.5	0.8	0.4	0.9	0.7	0.8	0.8	0.9	1.0	0.8	0.6	1.2	0.8	1.0	1.1	0.1
Commuting to job workplace: Public transport	0.6	0.7	3.0	-0.1	-1.1	-0.5	-1.5	0.2	-0.6	0.0	0.3	0.2	-1.7	-0.7	-0.6	-0.2	-0.5	-0.2	-0.7	-0.8	-1.2	-0.8	-1.3	-1.2	-0.7	-1.4	-0.0
Prostate Cancer	0.5	0.7	3.9	0.1	0.5	0.5	0.4	-0.0	0.5	0.8	0.8	0.3	2.0	1.0	0.5	0.9	0.8	0.0	0.5	0.6	0.9	1.8	0.9	0.8	0.3	0.3	1.5
Tanning	0.5	6.7	14.7	-3.5	-2.8	-1.9	-0.5	-2.9	-3.8	-2.9	-2.7	-3.3	-1.4	-2.4	-3.8	-3.2	-2.1	-2.7	-3.3	-2.9	0.1	-2.8	-0.7	-1.5	-3.0	-0.1	-3.1
Ever had hysterectomy (womb removed)	0.5	0.6	2.5	-1.2	0.3	-0.1	1.3	-1.1	-0.4	0.2	-1.6	-0.9	1.2	-0.3	-0.5	-0.6	-0.2	-1.1	-0.5	-0.3	1.0	0.7	0.1	0.6	-0.9	0.7	-0.7
Vitamin and mineral supplements	0.5	0.6	2.3	-1.4	-0.0	-1.2	-0.4	-1.5	0.2	-0.1	-1.1	-1.5	-0.4	-0.4	0.0	-1.0	-0.6	-1.5	-0.5	-0.2	0.8	0.4	-0.1	-0.3	-1.0	0.2	-0.2
Medication: Co-codamol	0.5	0.6	4.7	-0.2	0.7	1.0	1.9	-0.0	-0.4	0.2	1.4	0.1	2.2	-0.4	-0.4	0.4	-0.0	-0.2	-0.6	-0.3	0.5	0.9	0.6	0.4	-0.2	0.1	-0.3
Relative age voice broke	0.5	0.7	2.7	1.6	0.3	0.2	-0.8	1.7	0.9	0.8	1.0	1.5	0.4	0.2	1.0	1.3	0.4	1.0	1.0	0.4	-0.9	0.4	-0.0	-0.3	0.7	-0.4	0.4
Trunk fat-free mass	0.5	3.1	11.0	-3.2	-1.1	-1.5	0.2	-3.1	-1.6	-0.4	-3.1	-3.3	0.2	-0.2	-1.8	-2.4	-0.4	-2.4	-1.8	-1.1	2.3	-0.6	0.2	0.5	-1.9	1.8	0.3
Lung cancer (father)	0.5	0.6	3.6	0.5	1.2	1.3	1.9	0.7	0.2	0.5	0.6	0.7	0.5	0.2	0.2	0.6	0.7	0.9	0.3	0.7	0.9	0.3	0.3	0.7	0.9	1.0	-0.6
Trunk predicted mass	0.5	2.8	10.2	-3.0	-0.9	-1.4	0.3	-2.9	-1.4	-0.3	-2.9	-3.2	0.4	-0.1	-1.6	-2.2	-0.3	-2.3	-1.7	-1.0	2.4	-0.5	0.3	0.6	-1.7	1.8	0.4
Birth weight of first child	0.5	0.9	3.4	-0.9	-1.2	-0.6	-0.6	-0.7	-1.4	-1.9	-0.4	-0.6	-0.8	-0.7	-1.3	-1.2	-1.0	-0.4	-1.1	-1.2	-0.7	-1.4	-0.3	-0.9	-0.7	-0.7	-1.1
Arm fat-free mass (right)	0.5	2.4	11.0	-0.9	1.2	0.4	1.7	-1.1	0.7	2.0	-1.2	-1.2	1.7	1.9	0.6	-0.0	1.7	-0.3	0.7	1.2	3.3	1.4	1.6	2.2	0.4	2.9	2.1
Angina (self-reported)	0.5	0.7	3.3	-0.6	0.6	-0.2	0.3	-0.6	0.8	1.3	-0.7	-0.6	1.4	0.5	0.7	0.1	0.8	-0.5	0.5	1.0	1.8	1.3	0.7	1.1	0.2	1.2	0.9
Commuting to job workplace: Walk	0.5	0.5	3.3	1.1	0.1	0.7	0.0	1.0	0.1	-0.3	1.8	1.1	-0.6	0.7	0.2	0.7	0.1	1.0	0.5	0.1	-1.4	-0.4	0.1	-0.5	0.7	-0.8	-0.2
Number of self-reported non-cancer illnesses	0.5	0.8	3.4	1.0	0.8	1.8	1.0	1.2	0.4	0.8	1.5	1.6	0.6	0.1	0.5	1.4	0.8	1.2	0.4	0.2	0.2	0.7	-0.2	0.5	0.8	-0.5	-0.4
Arm fat-free mass (left)	0.5	2.4	11.6	-1.1	1.1	0.2	1.6	-1.3	0.7	1.8	-1.5	-1.5	1.6	1.9	0.5	-0.3	1.6	-0.5	0.5	1.1	3.4	1.2	1.7	2.2	0.3	3.1	2.1
Basal cell carcinoma (self-reported)	0.5	0.6	3.0	0.9	0.4	1.3	0.7	1.2	0.2	0.3	1.7	1.1	1.2	-0.3	0.2	1.0	0.5	1.3	0.3	0.4	-0.3	0.3	0.1	0.2	0.9	0.4	-0.2
Irritable Bowel Disease (IBD)	0.4	1.0	3.6	1.6	0.3	0.6	0.2	1.9	-0.1	-0.8	1.8	1.7	0.1	-0.2	0.1	1.1	0.1	1.8	0.4	0.4	-1.7	-1.0	-0.2	-0.5	1.2	-0.5	-1.1
Diabetes (father)	0.4	0.5	1.5	-0.9	-1.1	-0.7	-0.5	-0.7	-1.0	-0.3	-0.4	-0.5	-0.1	-0.6	-1.0	-0.5	-0.4	-0.9	-1.2	-1.2	-0.5	-0.5	-0.8	-0.4	-1.1	-0.6	0.7
Heart attack	0.4	0.5	1.9	0.1	0.3	-0.4	-0.7	-0.3	1.1	1.3	-0.4	-0.1	0.9	0.3	1.0	0.5	0.6	-0.1	0.9	0.9	0.9	1.4	0.3	0.8	0.3	0.4	0.7
Medication: Simvastatin	0.4	0.6	1.6	1.0	0.6	0.5	0.3	0.9	0.7	1.3	0.8	0.7	1.1	-0.1	0.8	0.9	0.8	1.0	0.7	0.6	0.9	0.8	0.6	0.6	0.9	0.8	0.3
Falls in the last year	0.4	0.6	1.5	-1.2	-0.5	-0.6	0.1	-1.1	-0.7	-0.8	-0.6	-1.0	0.1	-0.9	-0.8	-0.8	-0.8	-1.2	-1.0	-0.7	0.2	0.1	-0.5	-0.5	-1.1	-0.6	-0.8
Birth weight	0.4	0.9	2.5	-1.1	-0.7	-1.2	-0.0	-0.9	-1.0	-1.1	-0.5	-1.3	-1.2	-0.6	-1.1	-1.4	-0.8	-0.9	-1.3	-1.3	-0.3	-1.6	-0.3	-1.1	-1.1	0.6	-0.6
Medication: Ibuprofen	0.4	0.5	1.3	0.1	-1.0	-0.8	-1.0	-0.1	-0.9	-0.4	0.3	-0.2	-1.1	-0.8	-0.8	-0.1	-0.8	-0.2	-0.5	-0.8	-0.7	-0.5	-0.9	-1.2	-0.6	-1.0	-0.8
Arm predicted mass (right)	0.4	2.1	9.9	-1.0	1.1	0.3	1.5	-1.2	0.6	1.8	-1.4	-1.3	1.4	1.8	0.5	-0.1	1.6	-0.5	0.5	1.0	3.1	1.3	1.4	2.0	0.2	2.7	2.0
Supplements: Vitamin C	0.4	0.5	2.2	0.3	0.1	1.5	1.3	1.0	-0.8	0.7	1.3	0.9	0.7	-0.4	-0.7	0.8	0.5	0.9	-0.7	-0.9	-0.4	-0.3	-0.2	0.3	0.1	0.2	-0.1
Eye problems/disorders: Cataract	0.4	0.5	3.0	-0.6	0.4	0.4	1.4	-0.6	-0.5	0.4	-0.6	-0.7	1.0	-0.2	-0.6	-0.3	0.1	-0.2	-0.3	-0.0	1.7	0.7	0.5	0.4	-0.1	1.2	-0.3
Whole body water mass	0.4	2.1	7.6	-2.5	-0.3	-1.1	0.5	-2.5	-0.7	0.5	-2.6	-2.7	0.6	0.5	-0.9	-1.6	0.3	-1.8	-0.9	-0.3	2.8	0.1	0.6	1.1	-1.1	2.0	1.1
Supplements: Fish oil (including cod liver oil)	0.4	0.5	1.7	0.7	-0.7	0.4	-0.3	1.0	-0.9	-0.5	0.3	1.0	-0.2	-0.6	-0.8	0.3	-0.0	0.9	-0.5	-0.8	-1.3	-1.0	-0.8	-0.7	0.1	-0.6	-0.5
Unable to work because of sickness or disability	0.4	0.5	2.2	-0.2	0.7	0.4	1.2	-0.5	0.2	0.4	-0.1	-0.5	0.9	0.8	0.2	-0.2	0.4	-0.2	0.3	0.4	1.3	0.8	0.9	0.9	0.1	1.5	0.8
Cholesterol lowering medication	0.4	0.6	2.3	-0.6	-0.4	-0.8	-0.4	-0.6	-0.4	-0.4	-1.5	-0.6	-0.9	-1.5	-0.4	-0.7	-1.1	-0.6	-0.7	-0.7	0.2	-0.6	-1.1	-0.7	-0.7	-0.5	-1.3
Heart attack/myocardial infarction (self-reported)	0.4	0.5	2.0	0.1	0.2	-0.5	-0.6	-0.3	0.9	1.3	-0.4	-0.2	1.0	0.3	0.9	0.5	0.6	-0.2	0.8	0.8	0.9	1.4	0.3	0.7	0.2	0.5	0.8
Arm predicted mass (left)	0.4	1.9	9.4	-1.1	0.9	0.2	1.4	-1.2	0.4	1.6	-1.5	-1.4	1.4	1.7	0.3	-0.3	1.5	-0.5	0.3	0.8	3.1	1.0	1.4	1.9	0.2	2.7	1.9
Bipolar Disorder (2018)	0.3	0.5	2.2	0.5	0.4	-0.1	-0.0	0.1	0.6	0.8	1.1	-0.3	1.4	0.5	0.5	0.3	0.5	0.4	0.7	0.7	0.5	0.4	0.9	0.6	0.6	1.4	1.5
Waist Hip Ratio (WHR)	0.3	1.3	3.5	1.4	1.1	-0.0	-0.0	1.1	1.8	0.9	0.7	0.8	0.2	1.4	1.8	0.6	1.0	1.1	1.9	1.7	0.2	0.5	1.4	0.9	1.5	1.4	0.9
Number of treatments/medications taken	0.3	0.6	3.5	-0.2	-0.4	0.1	0.5	0.1	-1.2	-0.4	0.5	0.2	0.4	-1.4	-1.2	-0.0	-0.5	0.2	-1.2	-1.1	-0.3	-0.5	-0.7	-0.8	-0.4	-0.7	-1.9
Average weekly spirits intake	0.3	0.4	2.3	-0.5	-0.4	-0.4	-0.6	-0.6	0.0	-0.5	-0.9	-0.7	-1.5	-0.5	-0.0	-0.7	-0.6	-0.6	-0.5	-0.4	-0.4	-0.5	-0.7	-0.8	-0.6	-0.7	-0.7
Relative age of first facial hair	0.3	0.6	2.9	-0.0	-1.2	-0.9	-1.7	0.0	-0.6	-0.0	-0.0	0.1	-0.1	-0.7	-0.6	-0.1	-0.6	-0.4	-0.7	-1.0	-1.2	-0.4	-1.2	-1.0	-0.8	-1.4	0.4
Leg fat-free mass (left)	0.3	1.4	7.7	-1.3	0.5	-0.4	0.7	-1.4	0.4	1.3	-1.6	-1.5	1.0	1.1	0.2	-0.6	1.1	-0.8	0.1	0.8	2.8	0.7	0.9	1.6	0.0	2.1	1.5
Hand grip strength (right)	0.3	0.9	2.2	-0.8	-0.5	-0.5	-0.1	-0.6	-0.8	-1.0	-0.3	-0.6	-1.2	-1.2	-0.8	-1.0	-1.1	-1.0	-1.0	-1.0	-1.2	-1.1	-0.9	-1.1	-1.1	-1.5	-1.1
Fed-up feelings	0.3	0.6	1.5	-0.9	-0.6	-0.5	0.4	-1.0	-1.2	-0.9	-0.2	-1.2	0.6	0.0	-1.2	-1.0	-0.3	-0.6	-1.1	-1.0	0.4	-0.8	0.6	-0.1	-0.7	0.9	-0.6
Multivitamins +/- minerals	0.3	0.3	1.3	0.6	-1.1	-0.2	-1.1	0.6	-0.7	-0.4	0.3	0.5	-0.2	-0.4	-0.6	0.3	-0.0	0.6	-0.3	-0.4	-1.0	-0.8	-0.7	-0.4	0.2	-0.7	-0.2
Leg predicted mass (left)	0.3	1.3	7.6	-1.2	0.5	-0.4	0.7	-1.4	0.3	1.3	-1.5	-1.5	1.0	1.1	0.2	-0.5	1.1	-0.8	0.1	0.7	2.8	0.7	0.8	1.6	-0.0	2.1	1.5
Financial difficulties in last 2 years	0.3	0.5	1.6	-0.8	0.3	-0.4	-0.0	-0.9	0.7	1.0	-1.2	-1.0	-0.5	0.8	0.6	-0.4	0.3	-1.0	0.1	0.3	0.9	0.5	0.4	0.7	-0.3	0.4	1.1
Medication: Ramipril	0.3	0.4	2.8	-0.5	0.4	0.2	0.6	-0.5	0.3	0.8	-0.3	-0.5	1.1	0.5	0.2	0.1	0.7	-0.1	0.2	0.5	1.7	1.0	1.0	1.1	0.3	0.9	0.5
Medication: Cholesterol lowering	0.3	0.4	2.8	-0.4	-0.1	-0.4	-0.2	-0.6	0.2	1.2	-0.3	-0.8	0.7	0.4	0.2	0.1	0.7	-0.5	-0.0	0.1	1.7	1.1	0.4	0.6	-0.2	0.9	0.9
Prospective memory result	0.3	0.4	1.0	0.9	0.9	0.1	0.3	0.7	0.9	-0.2	0.0	0.5	1.0	0.3	0.9	0.0	0.1	0.5	0.9	0.7	-0.1	0.3	0.9	0.1	0.7	0.8	0.1
Mouth/teeth dental problems: Bleeding gums	0.3	0.4	1.2	0.8	0.6	0.4	0.6	1.0	0.3	0.5	0.8	1.0	0.7	0.8	0.4	1.1	0.5	0.9	0.4	0.2	-0.5	0.2	0.4	0.4	0.6	-0.2	0.6
Medication for cholesterol, blood pressure or diabetes	0.3	0.6	2.0	-0.7	-0.6	-0.6	-0.1	-0.8	-0.8	-1.4	-0.8	-0.6	-0.9	-0.4	-0.8	-1.0	-1.0	-0.6	-0.7	-0.7	-0.9	-0.9	-0.4	-0.7	-0.7	-0.9	-0.1
Exposure to tobacco smoke outside home	0.3	0.5	1.8	-1.1	-0.1	-0.6	0.6	-1.3	-0.6	-0.1	-0.5	-1.4	0.2	-0.4	-0.7	-0.8	-0.3	-1.1	-0.9	-0.6	0.8	-0.0	0.1	0.2	-0.8	0.6	-0.4
Medication for pain relief, constipation, heartburn	0.3	0.6	3.5	-1.0	0.2	-0.6	0.2	-1.3	0.4	-0.3	-1.9	-1.6	-0.7	0.3	0.3	-1.1	-0.2	-1.3	-0.0	0.2	0.7	-0.1	0.6	0.2	-0.6	0.6	0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.1	-0.9	-0.2	-0.4	0.1	-1.1	-0.3	-0.4	-0.9	-0.9	0.0	0.2	-0.3	-0.9	-0.5	-0.9	-0.2	-0.2	0.8	0.5	0.6	0.0	-0.7	0.0	0.2
Illnesses of father: Heart disease	0.3	0.4	2.4	0.4	0.2	-0.3	-0.9	0.2	1.0	1.0	0.3	0.1	0.4	0.9	0.9	0.4	0.4	0.2	0.9	0.6	0.3	0.9	0.1	0.6	0.3	0.4	1.6
Whole body fat-free mass	0.3	2.0	6.8	-2.4	-0.4	-1.1	0.4	-2.4	-0.7	0.4	-2.5	-2.6	0.6	0.5	-0.9	-1.6	0.3	-1.8	-0.9	-0.3	2.6	0.0	0.5	1.0	-1.1	2.0	1.0
Leg fat-free mass (right)	0.3	1.4	6.5	-1.8	0.1	-0.8	0.5	-1.9	-0.0	0.8	-2.0	-2.0	0.8	0.8	-0.2	-1.1	0.6	-1.3	-0.3	0.3	2.5	0.4	0.7	1.3	-0.5	1.8	1.3
Medication for cholesterol	0.3	0.5	1.9	0.3	0.9	0.7	1.1	0.2	0.5	0.2	0.8	-0.0	0.7	1.4	0.5	0.1	0.6	0.1	0.8	0.9	0.2	0.5	1.4	0.8	0.5	1.0	1.1
Medication: Gliclazide	0.3	0.3	1.0	0.8	0.3	0.9	-0.0	0.9	0.5	1.0	0.6	0.9	0.4	0.1	0.5	1.0	0.5	0.9	0.3	0.3	-0.1	0.4	-0.1	0.0	0.6	-0.2	0.4
Leg predicted mass (right)	0.3	1.5	6.9	-1.8	0.2	-0.8	0.5	-1.9	0.1	0.9	-2.0	-2.1	0.8	0.8	-0.1	-1.1	0.7	-1.3	-0.3	0.4	2.6	0.4	0.8	1.3	-0.4	1.9	1.3
Financial situation satisfaction	0.3	0.4	0.9	0.9	0.3	0.5	-0.6	0.8	0.9	0.1	0.9	0.8	0.3	0.7	0.9	0.9	0.6	0.9	0.7	0.6	-0.0	0.9	-0.1	-0.1	0.8	0.1	0.5
Basal metabolic rate	0.3	1.6	8.5	-1.4	0.5	-0.2	1.0	-1.4	0.3	1.2	-1.7	-1.7	1.1	1.2	0.1	-0.7	1.1	-0.8	0.1	0.7	2.9	0.6	1.1	1.7	-0.0	2.5	1.4
Supplements: Calcium	0.3	0.3	1.1	0.8	-0.1	0.7	0.2	1.1	-0.5	0.2	0.9	0.9	0.2	-0.1	-0.4	0.7	0.2	1.0	-0.1	-0.4	-1.1	-0.4	-0.2	-0.3	0.3	-0.4	0.1
Ever used hormone-replacement therapy (HRT)	0.2	0.3	2.2	0.4	0.4	0.0	1.1	0.6	-0.6	-0.3	0.2	0.4	0.5	-0.7	-0.5	0.2	-0.0	0.6	-0.2	-0.4	-0.4	-0.4	-0.0	-0.3	0.1	0.8	-1.5
Average weekly fortified wine intake	0.2	0.2	1.1	-0.1	-0.4	0.2	0.4	-0.1	-0.7	-0.1	1.1	0.2	0.3	-0.4	-0.7	0.4	0.0	-0.2	-0.4	-0.3	-0.1	0.4	-0.6	-0.4	-0.3	-0.8	-0.3
Bilateral oophorectomy (both ovaries removed)	0.2	0.2	0.7	-0.6	-0.0	-0.2	0.6	-0.3	-0.6	0.0	-0.4	-0.2	0.5	-0.6	-0.6	-0.2	-0.5	-0.4	-0.8	-0.8	0.1	0.2	-0.3	-0.2	-0.6	0.0	-0.8
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	1.1	0.6	-0.3	-0.4	-1.1	0.5	0.2	0.1	-0.1	0.6	0.1	0.5	0.2	0.4	0.1	0.4	0.3	0.2	-0.6	0.2	-0.2	-0.2	0.4	-0.5	0.1
Alcohol usually taken with meals	0.2	0.4	1.3	-0.9	-0.5	-0.2	0.2	-0.7	-0.9	0.0	0.0	-0.5	0.7	-0.1	-0.9	0.1	-0.1	-0.7	-1.0	-1.2	0.4	0.6	-0.5	-0.0	-0.9	-0.6	0.7
Had menopause	0.2	0.2	1.0	-0.0	0.1	0.0	0.8	0.1	-0.5	-0.8	-0.3	-0.1	-0.5	0.2	-0.5	-0.6	-0.0	0.2	0.1	-0.0	-0.1	-0.7	0.5	-0.1	0.1	0.6	-1.0
Time employed in main current job	0.2	0.3	2.4	0.4	0.7	1.4	1.6	0.4	-0.1	-0.2	0.2	0.4	-0.1	0.1	-0.1	0.3	0.0	0.3	0.0	-0.1	-0.4	-0.0	0.3	0.1	0.2	-0.1	-1.0
Father’s age at death	0.2	0.2	1.8	-0.2	0.2	0.9	1.3	0.1	-0.5	-0.4	0.7	-0.0	0.5	0.6	-0.5	-0.0	0.5	0.2	-0.4	-0.2	0.1	-0.1	0.9	0.2	0.1	-0.2	0.4
Medication: Allopurinol	0.2	0.2	1.4	-0.6	-0.3	-0.4	-0.4	-0.4	-0.2	-0.3	-1.2	-0.7	-0.7	0.1	-0.3	-0.7	-0.4	-0.3	-0.4	-0.1	0.6	-0.4	-0.2	-0.3	-0.2	0.5	-0.5
Long-standing illness, disability or infirmity	0.2	0.3	1.0	-0.1	-0.4	0.4	0.2	-0.0	-0.9	-0.1	0.2	0.3	0.4	-0.9	-0.8	0.2	-0.4	-0.0	-0.9	-1.0	-0.2	-0.0	-0.6	-0.5	-0.5	-0.5	-0.9
Mineral and other dietary supplements	0.2	0.3	1.5	0.1	-0.0	-0.8	-1.2	-0.3	1.0	-0.1	-0.1	-0.3	-1.1	0.1	0.9	-0.4	-0.4	-0.3	0.8	0.8	0.0	-0.1	-0.1	-0.2	0.2	-0.0	-0.1
Wears glasses or contact lenses	0.2	0.2	1.0	-0.3	0.2	0.1	0.1	-0.3	0.3	0.4	-0.1	-0.2	1.0	0.6	0.3	-0.0	0.4	-0.0	0.1	0.1	0.7	0.5	0.6	0.7	0.2	0.5	0.9
Ever taken oral contraceptive pill	0.2	0.2	0.9	0.6	-0.2	0.3	-0.5	0.6	-0.0	-0.1	0.3	0.6	-0.5	-0.3	0.0	0.1	-0.2	0.5	0.1	-0.1	-0.8	-0.5	-0.4	-0.4	0.2	-0.7	-1.0
Fractured/broken bones in last 5 years	0.2	0.2	0.8	0.4	-0.5	0.5	-0.3	0.5	-0.6	-0.2	0.3	0.6	-0.4	-0.5	-0.5	0.2	-0.4	0.4	-0.3	-0.5	-0.4	-0.2	-0.9	-0.6	0.0	-0.6	-0.6
HbA1C	0.1	0.1	0.7	-0.1	0.0	0.1	-0.1	0.3	0.1	0.0	0.0	0.2	0.1	-0.4	0.2	0.2	0.1	0.4	-0.1	0.2	0.1	-0.2	-0.2	-0.0	0.3	0.2	-0.8
Supplements: Zinc	0.1	0.1	0.5	-0.3	0.3	0.2	0.6	-0.4	-0.0	-0.3	-0.0	-0.6	0.1	-0.3	-0.0	-0.5	-0.1	-0.2	-0.2	-0.1	0.2	-0.1	0.3	0.2	-0.1	0.7	-0.5
Worrier / anxious feelings	0.1	0.3	1.2	0.6	-0.2	0.3	-0.3	0.7	-0.0	0.2	1.1	0.9	0.4	0.6	0.1	0.8	0.5	0.6	0.2	0.0	-0.4	0.5	-0.2	0.2	0.3	-0.6	0.9
Blood clot in the leg (DVT)	0.1	0.2	0.8	-0.3	0.0	0.5	0.8	0.0	-0.4	0.2	0.3	0.1	0.5	-0.0	-0.4	0.1	0.3	0.3	-0.1	0.0	0.9	-0.1	0.4	0.6	0.3	0.7	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.6	-0.2	0.3	0.0	0.2	-0.3	0.3	0.6	-0.0	0.1	0.1	-0.1	0.3	0.2	0.3	-0.6	0.0	0.1	0.3	0.8	-0.4	0.5	-0.3	-0.8	0.0
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.7	0.4	0.4	-0.3	-0.4	0.5	0.8	0.6	-0.0	0.4	0.1	0.0	0.8	0.6	0.1	0.2	0.4	0.2	-0.6	0.5	-0.4	-0.1	0.2	-0.2	0.1
Illnesses of father: None of the above (group 1)	0.1	0.1	0.8	-0.5	0.4	0.1	0.9	-0.5	0.0	-0.2	-0.1	-0.6	0.0	0.3	-0.0	-0.3	0.1	-0.3	-0.2	0.2	0.5	-0.1	0.4	0.3	-0.0	0.6	0.0
High cholesterol (Self-reported)	0.1	0.3	1.0	0.1	-0.1	-0.5	-0.7	-0.1	0.5	1.0	-0.8	0.0	0.5	0.1	0.4	0.4	0.4	-0.0	0.3	0.1	1.0	0.9	-0.4	0.4	0.0	0.7	0.7
Deep venous thrombosis (DVT) (self-reported)	0.1	0.1	0.7	-0.4	-0.1	0.4	0.6	-0.0	-0.5	0.1	0.1	-0.0	0.5	-0.1	-0.5	0.1	0.2	0.2	-0.1	-0.0	0.8	-0.1	0.4	0.6	0.1	0.6	-0.3
Blood Red Count	0.0	0.3	1.7	0.1	-0.4	-1.1	-1.3	-0.4	0.5	0.1	-0.6	-0.7	-0.1	0.4	0.5	-0.4	-0.1	-0.4	0.7	0.5	0.7	0.4	0.5	0.2	-0.0	0.8	0.9
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.1	0.6	-0.0	-0.2	0.5	0.1	-0.1	-0.4	-0.7	-0.0	-0.1	-0.1	0.1	-0.3	-0.2	0.0	0.4	0.0	0.2	0.2	-0.7	0.3	0.1	0.4	0.2	-0.2

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Trait associations