Best TWAS P=3.87e-11 · Best GWAS P=2.75e-08 conditioned to 0.0182
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | REEP2 | 0.12 | 0.02 | lasso | 6 | 0.02 | 0.03 | 4.9 | 5.4 | 5.5e-08 | -0.53 | 0.09 | 0.71 | FALSE |
| 2 | GTEx | Cells EBV-transformed lymphocytes | FAM53C | 0.22 | 0.01 | lasso | 10 | 0.00 | 0.34 | 5.2 | 6.6 | 3.9e-11 | -0.54 | 0.04 | 0.54 | TRUE |