Best TWAS P=4.81e-09 · Best GWAS P=9.36e-13 conditioned to 8.56e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | FTSJ2 | 0.23 | 0.07 | lasso | 5 | 0.08 | 2.5e-05 | -5.8 | -5.8 | 6.5e-09 | 0.76 | 0.17 | 0.81 | FALSE |
| 2 | GTEx | Heart Left Ventricle | FTSJ2 | 0.09 | 0.07 | enet | 7 | 0.06 | 2.9e-04 | -5.2 | -5.4 | 5.9e-08 | 0.72 | 0.15 | 0.70 | FALSE |
| 3 | GTEx | Pituitary | FTSJ2 | 0.23 | 0.04 | enet | 10 | 0.15 | 1.5e-04 | -6.0 | -5.7 | 1.6e-08 | 0.76 | 0.08 | 0.74 | FALSE |
| 4 | ROSMAP | Brain Pre-frontal Cortex | MAD1L1 | 0.11 | 0.03 | lasso | 3 | 0.07 | 4.7e-09 | 2.8 | 5.9 | 4.8e-09 | -0.63 | 0.53 | 0.22 | TRUE |