Best TWAS P=2.16e-09 · Best GWAS P=1.86e-08 conditioned to 0.0295
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | SDCCAG8 | 0.15 | 0.00 | enet | 24 | 0.00 | 1.8e-01 | 3.8 | 5.8 | 7.2e-09 | -0.40 | 0.09 | 0.16 | FALSE |
2 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | SDCCAG8 | 0.09 | 0.04 | blup | 114 | 0.08 | 4.6e-07 | 3.9 | 6.0 | 2.2e-09 | -0.67 | 0.32 | 0.64 | TRUE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SDCCAG8 | 0.06 | 0.02 | blup | 114 | 0.04 | 1.9e-05 | -4.6 | 5.4 | 5.4e-08 | -0.71 | 0.02 | 0.97 | FALSE |
4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CEP170 | 0.03 | 0.01 | lasso | 4 | 0.02 | 4.4e-03 | -5.1 | 5.7 | 1.6e-08 | -0.46 | 0.01 | 0.55 | FALSE |
5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SDCCAG8 | 0.10 | 0.05 | lasso | 4 | 0.06 | 5.8e-07 | -4.3 | 5.3 | 1.2e-07 | -0.62 | 0.07 | 0.92 | FALSE |
6 | The Cancer Genome Atlas | Rectum Adenocarcinoma | SDCCAG8 | 0.30 | 0.06 | blup | 113 | 0.12 | 8.0e-04 | 3.8 | 5.7 | 1.4e-08 | -0.57 | 0.09 | 0.26 | FALSE |