[Hub]/) : Traits : Number of operations (self-reported) :

chr4:105,598,022-107,092,169

Best TWAS P=4.22e-10 · Best GWAS P=4.55e-12 conditioned to 0.00462

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PPA2 0.08 0.03 bslmm 429 0.04 2.2e-05 -4.7 -5.7 1.1e-08 0.69 0.02 0.97 FALSE
2 GTEx Brain Cortex PPA2 0.14 0.09 lasso 9 0.09 1.6e-03 -5.8 -5.9 2.7e-09 0.81 0.05 0.62 FALSE
3 GTEx Breast Mammary Tissue (Female) PPA2 0.15 0.02 lasso 4 0.00 2.8e-01 -6.5 -5.7 9.1e-09 0.53 0.04 0.26 TRUE
4 GTEx Esophagus Gastroesophageal Junction PPA2 0.29 0.15 lasso 5 0.14 8.8e-06 -6.7 -6.2 4.2e-10 0.88 0.01 0.98 TRUE
5 The Cancer Genome Atlas Thyroid Carcinoma PPA2 0.04 0.02 blup 84 0.04 6.1e-05 -5.0 -5.3 1.2e-07 0.73 0.01 0.96 FALSE