[Hub]/) : Traits : Number of operations (self-reported) :

chr11:29,646,947-31,048,683

Best TWAS P=1.68e-09 · Best GWAS P=2.13e-08 conditioned to 0.145

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cerebellum ARL14EP 0.33 0.25 lasso 10 0.26 3.7e-08 5.1 -5.2 1.7e-07 -0.83 0.02 0.98 FALSE
2 GTEx Colon Sigmoid ARL14EP 0.16 0.05 lasso 13 0.10 2.6e-04 5.2 -5.8 6.3e-09 -0.65 0.06 0.68 FALSE
3 GTEx Esophagus Mucosa ARL14EP 0.09 0.03 enet 11 0.05 1.8e-04 5.2 -5.5 3.1e-08 -0.72 0.04 0.89 FALSE
4 GTEx Esophagus Muscularis ARL14EP 0.18 0.20 lasso 8 0.19 9.5e-12 4.9 -5.1 2.9e-07 -0.88 0.02 0.98 FALSE
5 GTEx Nerve Tibial ARL14EP 0.19 0.17 enet 22 0.18 4.2e-13 4.9 -6.0 1.7e-09 -0.78 0.03 0.97 TRUE
6 GTEx Ovary ARL14EP 0.35 0.21 enet 31 0.18 2.8e-05 4.9 -5.4 8.0e-08 -0.78 0.03 0.83 FALSE
7 GTEx Pancreas ARL14EP 0.16 0.08 lasso 6 0.07 1.0e-03 5.6 -5.6 1.8e-08 -0.95 0.01 0.97 FALSE
8 GTEx Thyroid ARL14EP 0.20 0.05 lasso 6 0.09 1.0e-07 -4.0 -5.7 1.4e-08 -0.52 0.60 0.35 FALSE
9 ROSMAP Brain Pre-frontal Cortex ARL14EP 0.08 0.07 enet 13 0.08 5.3e-10 4.9 -5.6 1.6e-08 -0.85 0.02 0.98 FALSE