Best TWAS P=6.78e-09 · Best GWAS P=3.89e-08 conditioned to 0.0363
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CASC10 | 0.05 | 0.06 | lasso | 4 | 0.02 | 0.013 | 5.0 | 5.8 | 6.8e-09 | 0.50 | 0.05 | 0.88 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | CASC10 | 0.08 | 0.02 | lasso | 5 | 0.01 | 0.061 | 5.5 | 5.2 | 2.4e-07 | 0.94 | 0.03 | 0.94 | TRUE |