TWAS
hub
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Usage
Models
Genes
Traits
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Traits
:
Alcohol intake frequency.
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chr1:752,566-1,620,860
Best TWAS P=6.63e-08 · Best GWAS P=1.41e-07 conditioned to 0.0634
0.8M
0.9M
1M
1.1M
1.2M
1.3M
1.4M
1.5M
1.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Skin Not Sun Exposed Suprapubic
RP11-54O7.17
0.23
0.10
enet
16
0.14
3.1e-08
-4.6
5.4
6.6e-08
-0.75
0.03
0.94
TRUE
2
GTEx
Skin Sun Exposed Lower leg
RP11-54O7.17
0.19
0.07
lasso
6
0.12
9.4e-10
-4.4
5.1
3.0e-07
-0.83
0.02
0.97
FALSE