Best TWAS P=1.22e-14 · Best GWAS P=1.69e-13 conditioned to 0.848
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | CTC-498M16.2 | 0.11 | 0.13 | lasso | 6 | 0.12 | 1.2e-14 | -7.2 | -7.7 | 1.2e-14 | 0.95 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Adenocarcinoma | LOC645323 | 0.05 | 0.01 | blup | 72 | 0.01 | 2.8e-02 | 5.7 | -6.6 | 4.7e-11 | 0.57 | 0.01 | 0.59 | FALSE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | TMEM161B | 0.03 | 0.01 | blup | 48 | 0.01 | 4.6e-02 | -5.9 | -6.2 | 5.4e-10 | 0.59 | 0.02 | 0.33 | FALSE |