TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Alcohol intake frequency.
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chr5:87,006,055-88,429,077
Best TWAS P=1.22e-14 · Best GWAS P=1.69e-13 conditioned to 0.848
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
CTC-498M16.2
0.11
0.13
lasso
6
0.12
1.2e-14
-7.2
-7.7
1.2e-14
0.95
0.01
0.99
TRUE
2
The Cancer Genome Atlas
Lung Adenocarcinoma
LOC645323
0.05
0.01
blup
72
0.01
2.8e-02
5.7
-6.6
4.7e-11
0.57
0.01
0.59
FALSE
3
The Cancer Genome Atlas
Thyroid Carcinoma
TMEM161B
0.03
0.01
blup
48
0.01
4.6e-02
-5.9
-6.2
5.4e-10
0.59
0.02
0.33
FALSE