Best TWAS P=3.27e-15 · Best GWAS P=1.07e-16 conditioned to 0.00784
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | CBX5 | 0.02 | 0.01 | lasso | 3 | 0.02 | 2.0e-07 | -8.3 | -7.1 | 1.0e-12 | 0.82 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SMUG1 | 0.08 | 0.05 | enet | 13 | 0.06 | 3.8e-07 | 3.5 | 5.8 | 7.2e-09 | -0.54 | 0.67 | 0.13 | FALSE |
| 3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | SMUG1 | 0.18 | 0.02 | blup | 42 | 0.06 | 2.1e-03 | 3.7 | 5.4 | 7.7e-08 | -0.46 | 0.02 | 0.75 | FALSE |
| 4 | The Cancer Genome Atlas | Rectum Adenocarcinoma | CBX5 | 0.16 | 0.10 | lasso | 4 | 0.11 | 1.5e-03 | -8.3 | -7.9 | 3.3e-15 | 0.92 | 0.01 | 0.71 | TRUE |
| 5 | The Cancer Genome Atlas | Skin Cutaneous Melanoma | SMUG1 | 0.28 | 0.12 | enet | 15 | 0.18 | 1.9e-05 | -2.8 | 5.4 | 6.2e-08 | -0.42 | 0.07 | 0.46 | FALSE |