Best TWAS P=8.45e-09 · Best GWAS P=6.06e-08 conditioned to 0.183
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Not Sun Exposed Suprapubic | TUBG2 | 0.15 | 0.13 | lasso | 5 | 0.12 | 4.0e-07 | 5.4 | -5.3 | 1.3e-07 | -0.99 | 0.00 | 1.00 | FALSE |
2 | GTEx | Skin Sun Exposed Lower leg | TUBG2 | 0.14 | 0.10 | enet | 25 | 0.12 | 4.9e-10 | -3.6 | -5.4 | 5.6e-08 | -0.83 | 0.01 | 0.98 | FALSE |
3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | TUBG2 | 0.02 | 0.01 | lasso | 2 | 0.01 | 1.7e-02 | 5.3 | -5.4 | 7.0e-08 | -0.86 | 0.00 | 0.74 | FALSE |
4 | The Cancer Genome Atlas | Lung Adenocarcinoma | TUBG2 | 0.07 | 0.01 | enet | 7 | 0.02 | 2.2e-03 | 5.3 | -5.8 | 8.4e-09 | -0.80 | 0.00 | 0.86 | TRUE |
5 | The Cancer Genome Atlas | Thyroid Carcinoma | TUBG2 | 0.20 | 0.13 | blup | 29 | 0.17 | 1.7e-16 | 5.3 | -5.6 | 1.8e-08 | -0.84 | 0.00 | 1.00 | FALSE |