Best TWAS P=2.62e-08 · Best GWAS P=2.43e-09 conditioned to 0.00328
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | CADM2 | 0.05 | 0.06 | lasso | 10 | 0.06 | 1.3e-09 | -5.8 | -5.5 | 3.6e-08 | 0.92 | 0.02 | 0.98 | FALSE |
2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | CADM2 | 0.05 | 0.03 | lasso | 3 | 0.04 | 5.0e-05 | -5.6 | -5.6 | 2.6e-08 | 0.69 | 0.09 | 0.91 | TRUE |