Best TWAS P=7.57e-10 · Best GWAS P=9.61e-13 conditioned to 2.38e-07
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | INO80D | 0.03 | 0.03 | enet | 12 | 0.04 | 2.8e-05 | 5.0 | 5.1 | 3.1e-07 | 0.47 | 0.58 | 0.21 | FALSE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | GPR1 | 0.05 | 0.04 | lasso | 3 | 0.04 | 1.7e-04 | 5.6 | -6.2 | 7.6e-10 | -0.38 | 0.30 | 0.11 | TRUE |