Best TWAS P=1.58e-10 · Best GWAS P=3.24e-07 conditioned to 0.322
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | BBS9 | 0.29 | 0.36 | enet | 31 | 0.39 | 8.1e-51 | 5.1 | -5.7 | 1.3e-08 | -0.96 | 0.00 | 0.99 | FALSE |
2 | The Cancer Genome Atlas | Glioblastoma Multiforme | BBS9 | 0.17 | 0.04 | blup | 234 | 0.05 | 1.5e-02 | 4.7 | -6.1 | 9.0e-10 | -0.63 | 0.03 | 0.76 | FALSE |
3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | BBS9 | 0.22 | 0.13 | blup | 232 | 0.16 | 2.6e-17 | 5.1 | -6.4 | 1.6e-10 | -0.69 | 0.00 | 0.99 | TRUE |