[Hub]/) : Traits : Comparative height size at age 10 :

chr7:134,650,544-136,073,677

Best TWAS P=5.9e-10 · Best GWAS P=1.35e-13 conditioned to 1.11e-08

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous C7orf73 0.23 0.14 lasso 7 0.18 9.5e-15 5.0 -5.7 1.6e-08 0.36 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum C7orf73 0.18 0.11 lasso 4 0.09 2.8e-05 5.0 -5.2 1.6e-07 0.40 0.94 0.01 FALSE
3 GTEx Adrenal Gland C7orf73 0.24 0.23 lasso 1 0.21 3.8e-08 6.0 -6.0 2.5e-09 0.34 0.74 0.08 FALSE
4 GTEx Artery Aorta C7orf73 0.27 0.23 lasso 4 0.21 1.5e-11 6.0 -5.9 4.6e-09 0.33 0.96 0.04 FALSE
5 GTEx Artery Coronary C7orf73 0.40 0.29 enet 18 0.30 1.3e-10 5.0 -5.6 2.5e-08 0.42 0.99 0.01 FALSE
6 GTEx Artery Tibial C7orf73 0.18 0.18 lasso 5 0.18 2.5e-14 5.0 -5.5 3.2e-08 0.34 0.99 0.01 FALSE
7 GTEx Breast Mammary Tissue C7orf73 0.15 0.11 lasso 6 0.15 4.3e-08 5.0 -5.8 6.8e-09 0.35 0.96 0.01 FALSE
8 GTEx Breast Mammary Tissue (Female) C7orf73 0.20 0.17 lasso 4 0.12 1.5e-04 6.0 -6.0 1.6e-09 0.37 0.30 0.06 FALSE
9 GTEx Cells EBV-transformed lymphocytes C7orf73 0.49 0.28 enet 33 0.44 7.4e-16 5.0 -5.1 2.8e-07 0.26 1.00 0.00 FALSE
10 GTEx Cells Transformed fibroblasts C7orf73 0.44 0.49 lasso 8 0.53 5.3e-46 5.0 -5.5 4.5e-08 0.36 1.00 0.00 FALSE
11 GTEx Colon Sigmoid C7orf73 0.25 0.22 lasso 2 0.21 6.1e-08 6.0 -6.2 5.9e-10 0.32 0.60 0.05 TRUE
12 GTEx Colon Transverse C7orf73 0.25 0.29 lasso 5 0.24 1.1e-11 6.0 -5.8 8.0e-09 0.33 0.95 0.05 FALSE
13 GTEx Esophagus Gastroesophageal Junction C7orf73 0.25 0.19 lasso 3 0.14 8.6e-06 5.0 -5.3 9.2e-08 0.32 0.53 0.04 FALSE
14 GTEx Esophagus Mucosa C7orf73 0.42 0.31 lasso 6 0.38 1.3e-26 6.0 -6.1 1.1e-09 0.35 0.95 0.05 FALSE
15 GTEx Esophagus Muscularis C7orf73 0.22 0.31 lasso 2 0.29 8.8e-18 6.0 -6.0 2.2e-09 0.35 0.95 0.05 FALSE
16 GTEx Heart Left Ventricle C7orf73 0.14 0.09 lasso 12 0.07 2.1e-04 5.5 -5.9 4.3e-09 0.42 0.89 0.02 FALSE
17 GTEx Lung C7orf73 0.26 0.21 lasso 10 0.22 1.5e-16 6.0 -6.0 2.5e-09 0.35 0.96 0.04 FALSE
18 GTEx Nerve Tibial C7orf73 0.19 0.10 lasso 9 0.18 9.5e-13 5.0 -5.5 4.4e-08 0.27 0.99 0.01 FALSE
19 GTEx Pancreas C7orf73 0.22 0.28 lasso 8 0.28 4.5e-12 5.0 -5.5 3.9e-08 0.33 0.99 0.01 FALSE
20 GTEx Skin Not Sun Exposed Suprapubic C7orf73 0.38 0.33 lasso 5 0.37 2.3e-21 5.0 -5.7 1.5e-08 0.36 1.00 0.00 FALSE
21 GTEx Skin Sun Exposed Lower leg C7orf73 0.29 0.28 enet 21 0.32 3.2e-27 5.0 -5.8 8.5e-09 0.35 1.00 0.00 FALSE
22 GTEx Stomach C7orf73 0.29 0.17 lasso 6 0.13 6.3e-07 6.0 -5.8 5.3e-09 0.33 0.96 0.04 FALSE
23 GTEx Testis C7orf73 0.38 0.27 lasso 4 0.30 1.1e-13 5.0 -5.3 1.0e-07 0.32 0.97 0.03 FALSE
24 GTEx Thyroid C7orf73 0.18 0.11 lasso 7 0.16 2.1e-12 5.0 -5.7 1.2e-08 0.38 1.00 0.00 FALSE
25 GTEx Vagina C7orf73 0.27 0.19 lasso 3 0.17 9.3e-05 5.0 -5.8 6.2e-09 0.39 0.23 0.12 FALSE
26 The Cancer Genome Atlas Breast Invasive Carcinoma PL-5283 0.33 0.24 enet 14 0.24 1.5e-48 5.0 -5.7 9.9e-09 0.39 0.00 1.00 FALSE
27 The Cancer Genome Atlas Colon Adenocarcinoma PL-5283 0.52 0.40 lasso 4 0.42 6.8e-26 5.0 -5.2 2.1e-07 0.33 0.00 1.00 FALSE
28 The Cancer Genome Atlas Colon Adenocarcinoma SLC13A4 0.46 0.24 lasso 3 0.24 2.4e-14 5.0 5.2 1.9e-07 -0.33 0.00 1.00 FALSE
29 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma SLC13A4 0.27 0.04 enet 10 0.15 4.8e-09 5.0 5.2 2.3e-07 -0.29 0.00 0.99 FALSE
30 The Cancer Genome Atlas Lung Adenocarcinoma PL-5283 0.40 0.24 lasso 5 0.26 4.2e-30 5.0 -5.4 8.5e-08 0.33 0.00 1.00 FALSE
31 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma SLC13A4 0.33 0.16 lasso 3 0.16 5.5e-07 5.0 5.4 7.3e-08 -0.35 0.00 0.99 FALSE
32 The Cancer Genome Atlas Soft Tissue Sarcoma NUP205 0.07 0.05 lasso 4 0.04 2.7e-03 5.5 -5.2 1.6e-07 0.29 0.01 0.61 FALSE
33 The Cancer Genome Atlas Soft Tissue Sarcoma PL-5283 0.20 0.12 lasso 2 0.11 5.1e-07 5.0 -5.3 1.1e-07 0.31 0.00 1.00 FALSE
34 The Cancer Genome Atlas Testicular Germ Cell Tumors PL-5283 0.40 0.26 enet 9 0.23 1.5e-08 5.0 -5.2 2.0e-07 0.34 0.00 1.00 FALSE
35 The Cancer Genome Atlas Thyroid Carcinoma PL-5283 0.59 0.38 lasso 6 0.42 1.5e-44 5.0 -5.4 5.7e-08 0.36 0.00 1.00 FALSE
36 The Cancer Genome Atlas Thyroid Carcinoma SLC13A4 0.44 0.18 blup 56 0.24 2.0e-23 5.0 5.4 7.5e-08 -0.34 0.00 1.00 FALSE