Best TWAS P=1.75e-08 · Best GWAS P=3.86e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | MEGF9 | 0.19 | 0.18 | lasso | 6 | 0.18 | 6.7e-15 | 5.5 | 5.3 | 1.0e-07 | 0.99 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Adipose Visceral Omentum | MEGF9 | 0.10 | 0.08 | enet | 8 | 0.07 | 1.6e-04 | 5.5 | 5.6 | 1.8e-08 | 0.97 | 0.01 | 0.98 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | MEGF9 | 0.11 | 0.10 | lasso | 5 | 0.12 | 2.7e-10 | 5.3 | 5.4 | 7.2e-08 | 0.99 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | MEGF9 | 0.02 | 0.03 | blup | 51 | 0.02 | 2.4e-03 | 4.9 | 5.3 | 1.4e-07 | 0.97 | 0.01 | 0.92 | FALSE |