[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr9:138,403,706-140,321,666

Best TWAS P=1.71e-23 · Best GWAS P=6.93e-19 conditioned to 3.12e-12

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	INPP5E	0.18	0.14	enet	21	0.21	1.6e-24	6.4	-6.8	7.7e-12	-0.03	1.00	0.00	FALSE
2	CommonMind	Brain Pre-frontal Cortex	QSOX2	0.18	0.11	lasso	4	0.10	1.0e-12	8.9	10.0	1.7e-23	0.94	0.00	1.00	TRUE
3	CommonMind	Brain Pre-frontal Cortex	SNAPC4	0.06	0.04	lasso	2	0.05	9.0e-07	4.9	-5.2	1.7e-07	0.01	0.96	0.00	FALSE
4	GTEx	Adipose Subcutaneous	SDCCAG3	0.13	0.00	enet	21	0.04	4.8e-04	5.3	-5.4	8.5e-08	0.00	0.20	0.03	FALSE
5	GTEx	Adrenal Gland	INPP5E	0.18	0.02	enet	23	0.10	2.2e-04	5.4	-7.7	1.3e-14	-0.18	0.21	0.09	TRUE
6	GTEx	Artery Tibial	SDCCAG3	0.05	0.00	lasso	4	0.00	2.2e-01	-4.3	-5.5	3.5e-08	0.04	0.30	0.04	FALSE
7	GTEx	Brain Caudate basal ganglia	INPP5E	0.23	0.20	enet	8	0.22	7.2e-07	6.4	-6.3	3.9e-10	-0.02	0.61	0.02	FALSE
8	GTEx	Brain Caudate basal ganglia	SNHG7	0.37	0.10	lasso	6	0.27	2.5e-08	-3.6	7.8	8.7e-15	0.05	0.17	0.05	TRUE
9	GTEx	Brain Cerebellar Hemisphere	INPP5E	0.25	0.23	enet	6	0.17	3.4e-05	6.5	-6.9	6.5e-12	-0.02	0.68	0.02	FALSE
10	GTEx	Brain Cerebellar Hemisphere	GPSM1	0.26	0.07	lasso	4	0.11	9.6e-04	3.2	-5.6	2.7e-08	0.00	0.13	0.05	FALSE
11	GTEx	Brain Cerebellum	INPP5E	0.40	0.30	enet	20	0.29	3.6e-09	6.4	-6.8	7.6e-12	-0.01	1.00	0.00	FALSE
12	GTEx	Brain Putamen basal ganglia	INPP5E	0.28	0.20	enet	6	0.01	2.2e-01	5.9	-5.7	1.4e-08	0.01	0.32	0.05	FALSE
13	GTEx	Cells EBV-transformed lymphocytes	INPP5E	0.27	0.05	enet	21	0.14	2.0e-05	6.5	-5.4	8.2e-08	-0.05	0.15	0.05	FALSE
14	GTEx	Cells Transformed fibroblasts	QSOX2	0.40	0.25	enet	11	0.30	5.2e-23	-8.2	9.9	6.6e-23	0.74	0.29	0.71	FALSE
15	GTEx	Cells Transformed fibroblasts	SDCCAG3	0.12	0.03	enet	21	0.06	5.4e-05	5.3	-5.8	5.6e-09	-0.03	0.98	0.00	FALSE
16	GTEx	Cells Transformed fibroblasts	CARD9	0.10	0.01	enet	15	0.02	8.0e-03	-3.3	-6.6	3.4e-11	0.07	0.36	0.02	FALSE
17	GTEx	Colon Transverse	SDCCAG3	0.11	0.01	lasso	8	0.02	5.5e-02	5.3	-5.1	2.8e-07	-0.05	0.24	0.03	FALSE
18	GTEx	Esophagus Mucosa	INPP5E	0.11	0.12	lasso	3	0.12	1.0e-08	6.5	-6.8	8.6e-12	-0.01	1.00	0.00	FALSE
19	GTEx	Esophagus Muscularis	QSOX2	0.16	0.07	lasso	4	0.06	1.4e-04	8.7	8.0	1.4e-15	0.93	0.00	0.99	FALSE
20	GTEx	Esophagus Muscularis	SDCCAG3	0.10	0.02	enet	5	0.02	3.6e-02	4.9	-6.9	4.4e-12	-0.04	0.26	0.03	FALSE
21	GTEx	Heart Atrial Appendage	INPP5E	0.13	0.12	lasso	2	0.10	3.5e-05	6.8	-6.9	7.3e-12	-0.03	0.32	0.04	FALSE
22	GTEx	Lung	INPP5E	0.10	0.05	enet	13	0.04	6.1e-04	6.4	-6.2	6.0e-10	-0.02	0.76	0.01	FALSE
23	GTEx	Lung	CARD9	0.08	0.04	enet	6	0.04	2.5e-04	5.5	5.8	7.6e-09	-0.01	0.89	0.00	FALSE
24	GTEx	Nerve Tibial	INPP5E	0.13	0.17	enet	10	0.14	3.7e-10	6.6	-6.5	7.2e-11	-0.01	1.00	0.00	FALSE
25	GTEx	Nerve Tibial	QSOX2	0.22	0.12	enet	12	0.17	4.6e-12	8.0	7.9	3.4e-15	0.91	0.05	0.95	FALSE
26	GTEx	Ovary	INPP5E	0.24	0.13	enet	11	0.15	1.9e-04	5.8	-6.2	4.6e-10	0.00	0.16	0.05	FALSE
27	GTEx	Ovary	SEC16A	0.33	0.06	enet	10	0.14	3.4e-04	5.9	-8.9	6.5e-19	-0.22	0.06	0.08	FALSE
28	GTEx	Pancreas	SEC16A	0.28	0.10	enet	16	0.16	4.1e-07	6.9	-6.5	9.2e-11	0.07	0.90	0.00	FALSE
29	GTEx	Pituitary	INPP5E	0.21	0.24	lasso	3	0.14	1.8e-04	6.4	6.2	7.1e-10	0.05	0.28	0.04	FALSE
30	GTEx	Skin Sun Exposed Lower leg	INPP5E	0.10	0.10	lasso	2	0.09	5.2e-08	6.5	-6.5	9.1e-11	-0.01	1.00	0.00	FALSE
31	GTEx	Stomach	SEC16A	0.15	0.09	lasso	4	0.10	1.8e-05	6.8	-7.3	3.0e-13	-0.02	0.85	0.01	FALSE
32	GTEx	Stomach	SDCCAG3	0.24	0.07	lasso	4	0.05	1.9e-03	-5.2	-5.3	8.9e-08	0.02	0.21	0.04	FALSE
33	GTEx	Testis	INPP5E	0.24	0.32	enet	10	0.30	5.4e-14	6.6	-6.5	6.6e-11	-0.02	1.00	0.00	FALSE
34	GTEx	Testis	SDCCAG3	0.15	0.09	lasso	4	0.13	3.3e-06	5.3	-6.8	8.2e-12	-0.01	0.74	0.05	FALSE
35	GTEx	Thyroid	INPP5E	0.23	0.35	enet	16	0.37	8.2e-30	6.0	-6.9	6.5e-12	0.00	1.00	0.00	FALSE
36	GTEx	Thyroid	SDCCAG3	0.16	0.11	lasso	3	0.12	9.4e-10	5.3	-5.1	3.0e-07	-0.01	1.00	0.00	FALSE
37	GTEx	Uterus	INPP5E	0.60	0.04	enet	10	0.22	3.4e-05	6.5	-5.6	1.6e-08	0.01	0.10	0.08	FALSE
38	GTEx	Whole Blood	SEC16A	0.07	0.05	lasso	5	0.04	1.3e-04	6.9	-6.8	1.0e-11	-0.02	0.94	0.00	FALSE
39	GTEx	Whole Blood	SDCCAG3	0.07	0.03	enet	6	0.02	3.4e-03	5.0	-5.7	1.4e-08	0.01	0.68	0.02	FALSE
40	METSIM	Adipose	QSOX2	0.06	0.00	bslmm	370	0.02	1.8e-03	7.9	8.3	8.7e-17	0.46	0.02	0.90	FALSE
41	YFS	Blood	CARD9	0.22	0.37	lasso	5	0.39	1.3e-137	4.9	5.1	2.8e-07	-0.04	1.00	0.00	FALSE
42	YFS	Blood	INPP5E	0.33	0.55	lasso	6	0.57	2.9e-235	6.5	-6.7	2.0e-11	-0.02	1.00	0.00	FALSE
43	YFS	Blood	PMPCA	0.03	0.01	lasso	5	0.02	2.7e-07	6.0	5.4	7.4e-08	0.00	0.99	0.00	FALSE
44	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	SEC16A	0.12	0.02	enet	10	0.03	2.2e-03	-2.9	-5.2	1.8e-07	0.05	0.04	0.38	FALSE
45	The Cancer Genome Atlas	Breast Invasive Carcinoma	QSOX2	0.05	0.03	blup	32	0.03	2.8e-07	-8.2	8.7	3.3e-18	0.68	0.17	0.81	FALSE
46	The Cancer Genome Atlas	Breast Invasive Carcinoma	SDCCAG3	0.05	0.01	blup	61	0.01	7.9e-04	6.8	-5.3	1.5e-07	0.01	0.00	0.93	FALSE
47	The Cancer Genome Atlas	Breast Invasive Carcinoma	SEC16A	0.02	0.00	blup	69	0.01	1.0e-03	6.4	-6.1	1.1e-09	0.05	0.01	0.94	FALSE
48	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	INPP5E	0.25	0.10	lasso	3	0.09	4.9e-05	6.5	-6.7	2.8e-11	-0.03	0.02	0.94	FALSE
49	The Cancer Genome Atlas	Colon Adenocarcinoma	INPP5E	0.11	0.08	lasso	2	0.08	3.4e-05	6.5	-6.5	6.0e-11	-0.02	0.02	0.86	FALSE
50	The Cancer Genome Atlas	Colon Adenocarcinoma	SDCCAG3	0.08	0.01	lasso	4	0.02	3.1e-02	4.7	-6.4	2.1e-10	-0.02	0.01	0.78	FALSE
51	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	QSOX2	0.10	0.03	enet	6	0.06	3.4e-07	7.9	8.7	2.5e-18	0.75	0.01	0.99	FALSE
52	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	QSOX2	0.04	0.01	enet	4	0.03	3.6e-04	-8.2	9.5	1.7e-21	0.78	0.01	0.92	FALSE
53	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SDCCAG3	0.04	0.05	enet	6	0.04	5.1e-05	4.7	-5.3	9.0e-08	0.00	0.18	0.80	FALSE
54	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	INPP5E	0.07	0.04	blup	54	0.07	6.0e-05	6.3	-7.0	2.7e-12	-0.01	0.01	0.96	FALSE
55	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	QSOX2	0.10	0.11	lasso	2	0.10	1.6e-06	-8.2	8.4	4.2e-17	0.45	0.12	0.79	FALSE
56	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	SDCCAG3	0.05	0.01	blup	61	0.01	5.9e-02	6.4	-5.7	1.4e-08	-0.01	0.04	0.52	FALSE
57	The Cancer Genome Atlas	Brain Lower Grade Glioma	INPP5E	0.04	0.02	blup	54	0.03	4.4e-04	6.4	-6.1	1.2e-09	0.00	0.01	0.98	FALSE
58	The Cancer Genome Atlas	Brain Lower Grade Glioma	QSOX2	0.06	0.05	lasso	2	0.05	2.5e-06	8.9	10.0	1.9e-23	0.94	0.00	1.00	FALSE
59	The Cancer Genome Atlas	Brain Lower Grade Glioma	SNAPC4	0.13	0.05	enet	7	0.06	1.7e-07	5.6	-5.6	2.8e-08	0.02	0.32	0.61	FALSE
60	The Cancer Genome Atlas	Lung Adenocarcinoma	QSOX2	0.05	0.05	enet	4	0.05	2.7e-06	-8.2	9.7	2.6e-22	0.59	0.07	0.85	FALSE
61	The Cancer Genome Atlas	Prostate Adenocarcinoma	QSOX2	0.08	0.07	lasso	4	0.08	1.2e-08	-8.2	9.8	1.7e-22	0.74	0.04	0.96	FALSE
62	The Cancer Genome Atlas	Prostate Adenocarcinoma	SDCCAG3	0.08	0.05	lasso	2	0.05	3.3e-06	4.7	-5.2	1.9e-07	0.01	0.16	0.82	FALSE
63	The Cancer Genome Atlas	Prostate Adenocarcinoma	SEC16A	0.08	0.10	lasso	4	0.08	1.9e-08	6.1	-6.2	7.7e-10	-0.04	0.11	0.89	FALSE
64	The Cancer Genome Atlas	Skin Cutaneous Melanoma	QSOX2	0.28	0.01	enet	4	0.05	1.6e-02	-8.2	9.4	3.8e-21	0.70	0.00	0.46	FALSE
65	The Cancer Genome Atlas	Testicular Germ Cell Tumors	INPP5E	0.10	0.06	blup	54	0.08	8.1e-04	6.5	-6.6	5.2e-11	-0.01	0.03	0.75	FALSE
66	The Cancer Genome Atlas	Thyroid Carcinoma	INPP5E	0.11	0.16	lasso	3	0.16	2.4e-15	5.9	-6.0	2.0e-09	0.00	0.62	0.38	FALSE
67	The Cancer Genome Atlas	Thyroid Carcinoma	QSOX2	0.06	0.01	blup	32	0.05	1.6e-05	7.9	8.0	1.2e-15	0.65	0.00	0.95	FALSE