[Hub]/) : Traits : Comparative height size at age 10 :

chr10:78,845,149-80,383,574

Best TWAS P=2.31e-10 · Best GWAS P=9.98e-09 conditioned to 0.503

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DLG5 0.10 0.07 lasso 5 0.06 3.3e-08 -5.7 -5.6 2.5e-08 0.98 0.01 0.99 FALSE
2 GTEx Adipose Subcutaneous DLG5 0.39 0.40 lasso 12 0.43 1.9e-38 -5.7 -5.9 3.6e-09 0.97 0.00 1.00 FALSE
3 GTEx Adipose Subcutaneous RP13-39P12.3 0.31 0.27 lasso 12 0.34 1.1e-28 -5.6 -5.8 5.8e-09 0.90 0.01 0.99 FALSE
4 GTEx Adipose Visceral Omentum DLG5 0.26 0.23 lasso 8 0.21 5.7e-11 -5.6 -5.8 7.3e-09 0.97 0.01 0.99 FALSE
5 GTEx Adipose Visceral Omentum RP13-39P12.3 0.18 0.07 lasso 7 0.06 3.3e-04 -5.6 -5.8 9.1e-09 0.87 0.01 0.98 FALSE
6 GTEx Adrenal Gland DLG5 0.22 0.14 lasso 6 0.11 8.5e-05 -5.6 -5.9 3.2e-09 0.94 0.01 0.98 FALSE
7 GTEx Artery Aorta DLG5 0.26 0.19 enet 10 0.22 2.6e-12 -5.6 -5.6 2.6e-08 0.98 0.01 0.99 FALSE
8 GTEx Artery Aorta RP13-39P12.3 0.14 0.13 enet 9 0.12 2.2e-07 -5.6 -5.5 3.4e-08 0.97 0.01 0.99 FALSE
9 GTEx Artery Coronary DLG5 0.33 0.25 lasso 4 0.27 1.4e-09 -5.4 -5.8 6.3e-09 0.91 0.01 0.99 FALSE
10 GTEx Artery Coronary RP13-39P12.3 0.21 0.03 lasso 4 0.09 7.2e-04 -5.4 -5.6 2.5e-08 0.85 0.03 0.94 FALSE
11 GTEx Artery Tibial DLG5 0.24 0.18 lasso 5 0.18 9.7e-14 -5.6 -5.6 2.4e-08 0.98 0.01 0.99 FALSE
12 GTEx Artery Tibial RP13-39P12.3 0.14 0.04 lasso 7 0.05 7.3e-05 -5.6 -5.7 1.6e-08 0.85 0.02 0.98 FALSE
13 GTEx Brain Cerebellum DLG5 0.36 0.28 lasso 7 0.36 1.6e-11 -5.7 -5.9 2.9e-09 0.90 0.01 0.99 FALSE
14 GTEx Brain Cerebellum RP13-39P12.3 0.24 0.14 lasso 10 0.17 1.3e-05 3.9 -5.3 1.0e-07 0.72 0.06 0.88 FALSE
15 GTEx Breast Mammary Tissue DLG5 0.15 0.09 lasso 7 0.08 6.7e-05 -5.3 -5.6 2.6e-08 0.93 0.02 0.97 FALSE
16 GTEx Cells Transformed fibroblasts DLG5 0.25 0.18 lasso 11 0.16 2.0e-12 -5.6 -5.8 5.2e-09 0.96 0.01 0.99 FALSE
17 GTEx Cells Transformed fibroblasts RP13-39P12.3 0.19 0.13 lasso 7 0.15 4.5e-11 -5.6 -5.9 3.0e-09 0.90 0.01 0.99 FALSE
18 GTEx Colon Sigmoid DLG5 0.23 0.11 lasso 5 0.15 4.6e-06 4.1 -5.7 1.4e-08 0.82 0.03 0.94 FALSE
19 GTEx Colon Transverse DLG5 0.23 0.17 lasso 8 0.19 1.4e-09 -5.4 -5.7 9.9e-09 0.94 0.01 0.99 FALSE
20 GTEx Esophagus Gastroesophageal Junction DLG5 0.27 0.03 enet 13 0.06 3.9e-03 -4.5 -6.3 3.8e-10 0.73 0.02 0.95 FALSE
21 GTEx Esophagus Mucosa DLG5 0.21 0.16 lasso 5 0.18 5.2e-12 -5.7 -5.9 2.8e-09 0.94 0.01 0.99 FALSE
22 GTEx Heart Atrial Appendage DLG5 0.32 0.23 lasso 4 0.24 3.9e-11 -5.3 -5.6 2.4e-08 0.97 0.01 0.99 FALSE
23 GTEx Heart Atrial Appendage RP13-39P12.3 0.22 0.11 lasso 4 0.16 7.7e-08 4.1 -5.5 4.2e-08 0.80 0.03 0.96 FALSE
24 GTEx Heart Left Ventricle DLG5 0.13 0.10 lasso 4 0.09 1.2e-05 -5.3 -5.5 4.8e-08 0.97 0.01 0.99 FALSE
25 GTEx Liver DLG5 0.42 0.31 lasso 5 0.28 2.1e-08 -5.6 -5.5 5.0e-08 0.97 0.01 0.99 FALSE
26 GTEx Lung DLG5 0.41 0.38 lasso 8 0.37 7.9e-30 -5.6 -5.6 2.1e-08 0.98 0.01 0.99 FALSE
27 GTEx Lung RP13-39P12.3 0.36 0.28 enet 27 0.31 2.5e-24 -5.6 -5.3 1.2e-07 0.90 0.01 0.99 FALSE
28 GTEx Nerve Tibial DLG5 0.51 0.44 lasso 6 0.50 1.4e-39 -5.6 -5.7 1.1e-08 0.97 0.01 0.99 FALSE
29 GTEx Nerve Tibial RP13-39P12.3 0.31 0.25 lasso 7 0.36 1.3e-26 -5.6 -5.6 2.1e-08 0.86 0.01 0.99 FALSE
30 GTEx Ovary DLG5 0.62 0.38 lasso 6 0.40 5.3e-11 -5.6 -6.2 4.0e-10 0.96 0.01 0.99 FALSE
31 GTEx Ovary RP13-39P12.3 0.42 0.29 lasso 5 0.33 7.5e-09 -5.6 -6.3 2.3e-10 0.94 0.01 0.98 TRUE
32 GTEx Pancreas DLG5 0.39 0.43 enet 11 0.44 3.5e-20 -5.6 -5.6 2.7e-08 0.99 0.01 0.99 FALSE
33 GTEx Pancreas RP13-39P12.3 0.20 0.24 lasso 3 0.23 3.8e-10 -5.6 -5.6 1.9e-08 0.98 0.01 0.99 FALSE
34 GTEx Pituitary DLG5 0.45 0.36 lasso 11 0.31 1.9e-08 -5.6 -5.7 1.2e-08 0.97 0.01 0.99 FALSE
35 GTEx Pituitary RP13-39P12.3 0.38 0.22 lasso 11 0.17 3.8e-05 -5.6 -5.8 7.4e-09 0.95 0.02 0.96 FALSE
36 GTEx Skin Sun Exposed Lower leg DLG5 0.12 0.06 lasso 4 0.06 4.9e-06 -5.6 -5.8 6.3e-09 0.97 0.01 0.99 FALSE
37 GTEx Spleen DLG5 0.51 0.46 lasso 4 0.44 1.1e-12 -5.6 -5.7 1.5e-08 0.98 0.01 0.99 FALSE
38 GTEx Spleen RP13-39P12.3 0.38 0.34 lasso 2 0.35 8.8e-10 -5.6 -5.8 5.3e-09 0.94 0.01 0.99 FALSE
39 GTEx Stomach DLG5 0.20 0.12 lasso 7 0.08 1.3e-04 -5.6 -5.6 2.5e-08 0.98 0.01 0.99 FALSE
40 GTEx Stomach RP13-39P12.3 0.17 0.02 lasso 5 0.02 2.5e-02 4.1 -5.3 1.2e-07 0.79 0.02 0.88 FALSE
41 GTEx Thyroid DLG5 0.39 0.43 lasso 5 0.43 1.5e-35 -5.6 -5.6 2.0e-08 0.98 0.01 0.99 FALSE
42 GTEx Thyroid RP13-39P12.3 0.28 0.30 lasso 8 0.29 3.3e-22 -5.6 -5.8 7.3e-09 0.98 0.01 0.99 FALSE
43 GTEx Whole Blood DLG5 0.10 0.06 lasso 9 0.10 2.3e-09 3.8 -5.4 5.7e-08 0.79 0.08 0.92 FALSE
44 METSIM Adipose DLG5 0.18 0.19 lasso 11 0.22 2.2e-32 -5.6 -5.8 7.2e-09 0.90 0.01 0.99 FALSE
45 ROSMAP Brain Pre-frontal Cortex DLG5 0.19 0.17 bslmm 592 0.20 1.5e-24 -5.6 -5.4 7.2e-08 0.91 0.01 0.99 FALSE
46 The Cancer Genome Atlas Bladder Urothelial Carcinoma DLG5 0.08 0.00 blup 116 0.02 4.0e-03 -5.3 -5.2 2.5e-07 0.82 0.01 0.88 FALSE
47 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma DLG5 0.12 0.01 blup 116 0.03 1.2e-02 -5.4 -5.3 1.0e-07 0.83 0.02 0.66 FALSE
48 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma DLG5 0.09 0.05 blup 116 0.07 4.5e-05 3.8 -5.2 1.7e-07 0.78 0.08 0.91 FALSE
49 The Cancer Genome Atlas Brain Lower Grade Glioma DLG5 0.03 0.01 blup 116 0.02 6.9e-03 4.1 -5.4 7.2e-08 0.75 0.03 0.67 FALSE
50 The Cancer Genome Atlas Lung Adenocarcinoma DLG5 0.03 0.01 blup 116 0.02 3.1e-03 4.1 -5.2 1.7e-07 0.70 0.06 0.67 FALSE
51 The Cancer Genome Atlas Pancreatic Adenocarcinoma DLG5 0.15 0.00 blup 116 0.07 6.3e-04 -5.3 -5.3 1.1e-07 0.85 0.01 0.97 FALSE
52 The Cancer Genome Atlas Thyroid Carcinoma DLG5 0.13 0.08 enet 10 0.10 1.2e-09 -5.0 -5.6 1.9e-08 0.85 0.03 0.97 FALSE