Best TWAS P=7.15e-18 · Best GWAS P=8.5e-17 conditioned to 0.00961
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ZCCHC24 | 0.12 | 0.01 | lasso | 6 | 0.03 | 3.4e-03 | 7.848 | 8.6 | 7.1e-18 | 0.78 | 0.01 | 0.95 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | ZCCHC24 | 0.09 | 0.00 | enet | 18 | 0.00 | 2.3e-01 | 0.449 | 6.6 | 4.8e-11 | 0.43 | 0.03 | 0.59 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | RP11-342M3.5 | 0.08 | 0.00 | enet | 28 | 0.01 | 7.3e-02 | 0.044 | 5.2 | 1.7e-07 | 0.30 | 0.05 | 0.22 | FALSE |
| 4 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | ZCCHC24 | 0.06 | 0.00 | blup | 89 | 0.01 | 6.2e-02 | 2.669 | 7.2 | 5.9e-13 | 0.41 | 0.01 | 0.12 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ZCCHC24 | 0.07 | 0.05 | enet | 9 | 0.04 | 6.7e-05 | 7.349 | 7.6 | 2.6e-14 | 0.95 | 0.00 | 1.00 | FALSE |