[Hub]/) : Traits : Comparative height size at age 10 :

chr10:130,566,749-132,263,732

Best TWAS P=7.04e-12 · Best GWAS P=2.14e-12 conditioned to 7.43e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MGMT 0.29 0.27 lasso 14 0.31 6.0e-38 -5.5 5.4 6.1e-08 -0.77 0.10 0.90 FALSE
2 GTEx Adipose Subcutaneous MGMT 0.39 0.27 enet 30 0.48 1.2e-44 -5.7 5.2 1.5e-07 -0.69 0.60 0.40 FALSE
3 GTEx Adrenal Gland MGMT 0.39 0.25 lasso 6 0.30 1.5e-11 -5.5 5.9 3.9e-09 -0.77 0.11 0.88 FALSE
4 GTEx Artery Tibial MGMT 0.42 0.30 enet 22 0.46 1.9e-40 -6.8 5.6 1.7e-08 -0.80 0.01 0.99 FALSE
5 GTEx Brain Cerebellar Hemisphere MGMT 0.53 0.15 lasso 8 0.19 1.3e-05 -5.5 6.0 1.4e-09 -0.74 0.10 0.76 FALSE
6 GTEx Brain Nucleus accumbens basal ganglia MGMT 0.32 0.29 lasso 1 0.21 2.4e-06 -5.7 5.7 1.2e-08 -0.77 0.21 0.62 FALSE
7 GTEx Breast Mammary Tissue MGMT 0.60 0.21 enet 13 0.33 1.6e-17 -4.7 5.7 1.0e-08 -0.75 0.25 0.75 FALSE
8 GTEx Breast Mammary Tissue (Female) MGMT 0.46 0.31 lasso 4 0.33 1.1e-10 -4.7 5.4 5.5e-08 -0.68 0.20 0.77 FALSE
9 GTEx Cells Transformed fibroblasts MGMT 0.45 0.30 enet 31 0.42 4.8e-34 -5.7 5.8 6.6e-09 -0.78 0.78 0.22 FALSE
10 GTEx Colon Sigmoid MGMT 0.55 0.21 enet 29 0.29 9.1e-11 -4.7 6.0 2.1e-09 -0.63 0.03 0.97 FALSE
11 GTEx Esophagus Gastroesophageal Junction MGMT 0.34 0.31 lasso 6 0.28 9.8e-11 -6.8 6.4 1.4e-10 -0.87 0.01 0.99 FALSE
12 GTEx Esophagus Mucosa MGMT 0.41 0.33 enet 37 0.38 2.3e-26 -4.7 5.2 2.6e-07 -0.65 0.94 0.06 FALSE
13 GTEx Esophagus Muscularis MGMT 0.50 0.29 enet 40 0.34 3.4e-21 -4.7 5.2 2.4e-07 -0.64 0.54 0.46 FALSE
14 GTEx Heart Atrial Appendage MGMT 0.41 0.17 enet 33 0.22 4.6e-10 -4.7 6.8 1.5e-11 -0.77 0.07 0.93 FALSE
15 GTEx Heart Left Ventricle MGMT 0.27 0.20 lasso 7 0.22 6.3e-12 -4.7 5.2 2.3e-07 -0.66 0.86 0.14 FALSE
16 GTEx Liver MGMT 0.46 0.39 lasso 4 0.42 8.2e-13 -4.7 5.5 3.2e-08 -0.73 0.38 0.62 FALSE
17 GTEx Lung MGMT 0.39 0.24 enet 28 0.33 5.5e-26 -4.7 5.3 1.3e-07 -0.70 0.13 0.87 FALSE
18 GTEx Nerve Tibial MGMT 0.50 0.23 enet 46 0.42 6.9e-32 -5.7 5.2 2.1e-07 -0.70 0.01 0.99 FALSE
19 GTEx Ovary MGMT 0.52 0.09 enet 59 0.12 8.6e-04 -5.7 5.2 2.0e-07 -0.58 0.04 0.93 FALSE
20 GTEx Pancreas MGMT 0.32 0.03 lasso 7 0.17 8.0e-08 -4.7 6.0 1.8e-09 -0.57 0.19 0.73 FALSE
21 GTEx Prostate MGMT 0.25 0.13 lasso 4 0.20 9.4e-06 -5.5 6.2 4.0e-10 -0.83 0.03 0.92 FALSE
22 GTEx Skin Sun Exposed Lower leg MGMT 0.45 0.30 enet 42 0.46 1.6e-41 -6.8 6.0 1.6e-09 -0.73 0.01 0.99 FALSE
23 GTEx Small Intestine Terminal Ileum MGMT 0.31 0.14 enet 11 0.21 1.6e-05 -6.8 6.2 4.6e-10 -0.82 0.04 0.89 FALSE
24 GTEx Stomach MGMT 0.33 0.20 enet 9 0.25 2.3e-12 -6.1 6.2 4.0e-10 -0.81 0.32 0.68 FALSE
25 GTEx Thyroid MGMT 0.44 0.35 lasso 11 0.43 1.9e-35 -5.5 5.7 1.1e-08 -0.76 0.93 0.07 FALSE
26 GTEx Vagina MGMT 0.33 0.23 lasso 4 0.24 3.3e-06 -5.7 6.3 3.4e-10 -0.87 0.03 0.90 FALSE
27 METSIM Adipose MGMT 0.18 0.11 lasso 9 0.18 1.5e-25 -4.8 5.5 4.3e-08 -0.81 0.26 0.74 FALSE
28 NTR Blood MGMT 0.08 0.07 lasso 8 0.08 3.7e-24 -4.7 5.6 2.4e-08 -0.76 0.98 0.02 FALSE
29 ROSMAP Brain Pre-frontal Cortex MGMT 0.41 0.38 enet 46 0.48 3.6e-69 -4.7 5.7 1.4e-08 -0.74 0.99 0.01 FALSE
30 YFS Blood MGMT 0.50 0.40 enet 94 0.55 1.6e-218 -4.7 5.4 6.4e-08 -0.63 1.00 0.00 FALSE
31 The Cancer Genome Atlas Breast Invasive Carcinoma MGMT 0.16 0.17 enet 22 0.21 2.4e-41 -4.7 5.5 3.0e-08 -0.73 1.00 0.00 FALSE
32 The Cancer Genome Atlas Colon Adenocarcinoma MGMT 0.24 0.09 blup 238 0.14 2.3e-08 -6.8 5.3 1.1e-07 -0.67 0.03 0.97 FALSE
33 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MGMT 0.10 0.09 enet 23 0.10 1.9e-11 -5.7 5.4 5.6e-08 -0.73 0.67 0.33 FALSE
34 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MGMT 0.26 0.32 lasso 10 0.37 2.9e-43 -5.5 6.2 5.2e-10 -0.81 0.97 0.03 FALSE
35 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma MGMT 0.40 0.24 enet 29 0.37 1.9e-22 -5.5 5.7 1.1e-08 -0.67 0.52 0.48 FALSE
36 The Cancer Genome Atlas Liver Hepatocellular Carcinoma MGMT 0.25 0.05 blup 234 0.12 1.9e-06 -4.7 6.9 7.0e-12 -0.54 0.05 0.91 TRUE
37 The Cancer Genome Atlas Lung Adenocarcinoma MGMT 0.11 0.07 enet 16 0.14 2.8e-16 -4.7 5.2 1.9e-07 -0.78 0.46 0.54 FALSE
38 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma MGMT 0.27 0.24 lasso 7 0.19 3.3e-08 -5.4 5.2 1.7e-07 -0.69 0.10 0.89 FALSE
39 The Cancer Genome Atlas Prostate Adenocarcinoma MGMT 0.39 0.31 enet 60 0.35 1.8e-37 -4.7 5.5 3.8e-08 -0.57 1.00 0.00 FALSE
40 The Cancer Genome Atlas Soft Tissue Sarcoma MGMT 0.14 0.05 blup 235 0.11 5.4e-07 -6.9 5.6 2.7e-08 -0.75 0.02 0.98 FALSE
41 The Cancer Genome Atlas Stomach Adenocarcinoma MGMT 0.15 0.08 lasso 4 0.10 7.5e-08 -4.7 5.2 1.7e-07 -0.70 0.77 0.22 FALSE