Best TWAS P=7.89e-10 · Best GWAS P=1.54e-10 conditioned to 0.00531
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | METTL10 | 0.33 | 0.16 | lasso | 3 | 0.18 | 7.6e-06 | 5.6 | -5.8 | 5.9e-09 | -0.89 | 0.03 | 0.94 | FALSE |
| 2 | GTEx | Brain Frontal Cortex BA9 | METTL10 | 0.24 | 0.00 | lasso | 3 | 0.02 | 9.3e-02 | -3.9 | -6.2 | 7.9e-10 | -0.73 | 0.04 | 0.69 | TRUE |