Best TWAS P=4.66e-09 · Best GWAS P=2.87e-11 conditioned to 0.00162
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SUGT1L1 | 0.09 | 0.06 | lasso | 7 | 0.09 | 8.4e-18 | 3.7 | -5.8 | 8.5e-09 | 0.85 | 0.01 | 0.99 | FALSE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | SUGT1L1 | 0.06 | 0.01 | blup | 58 | 0.03 | 1.9e-04 | -6.4 | -5.2 | 2.5e-07 | 0.82 | 0.00 | 0.98 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SUGT1L1 | 0.29 | 0.23 | lasso | 8 | 0.25 | 1.7e-28 | 3.7 | -5.5 | 5.0e-08 | 0.81 | 0.98 | 0.02 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | SUGT1L1 | 0.32 | 0.22 | blup | 59 | 0.27 | 1.3e-30 | 3.7 | -5.2 | 1.8e-07 | 0.78 | 1.00 | 0.00 | FALSE |
| 5 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | SUGT1L1 | 0.22 | 0.07 | lasso | 11 | 0.13 | 9.4e-06 | -6.4 | -5.9 | 4.7e-09 | 0.88 | 0.01 | 0.96 | TRUE |
| 6 | The Cancer Genome Atlas | Prostate Adenocarcinoma | SUGT1L1 | 0.21 | 0.11 | lasso | 9 | 0.16 | 5.7e-16 | 3.7 | -5.8 | 7.2e-09 | 0.85 | 0.02 | 0.98 | FALSE |
| 7 | The Cancer Genome Atlas | Stomach Adenocarcinoma | SUGT1L1 | 0.09 | 0.06 | blup | 59 | 0.06 | 5.4e-05 | -6.4 | -5.8 | 8.0e-09 | 0.88 | 0.00 | 1.00 | FALSE |