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chr13:114,302,502-115,106,996

Best TWAS P=7.22e-14 · Best GWAS P=4.62e-13 conditioned to 0.236

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
41	The Cancer Genome Atlas	Colon Adenocarcinoma	CDC16	0.06	0.04	lasso	5	0.03	5.9e-03	-7.0	-7.5	7.2e-14	0.90	0.01	0.94	TRUE
25	GTEx	Nerve Tibial	CDC16	0.23	0.23	enet	19	0.26	9.5e-19	-6.8	-7.4	1.6e-13	0.78	0.03	0.97	FALSE
49	The Cancer Genome Atlas	Thyroid Carcinoma	CDC16	0.06	0.09	lasso	3	0.09	3.3e-09	-7.0	-7.3	2.2e-13	0.81	0.02	0.98	FALSE
17	GTEx	Colon Transverse	CDC16	0.18	0.23	lasso	5	0.21	3.2e-10	-6.9	-7.3	2.3e-13	0.78	0.03	0.97	FALSE
48	The Cancer Genome Atlas	Prostate Adenocarcinoma	CDC16	0.08	0.07	blup	49	0.08	1.2e-08	-7.2	-7.3	2.6e-13	0.83	0.00	1.00	FALSE
3	GTEx	Adipose Visceral Omentum	CDC16	0.12	0.11	lasso	4	0.09	1.5e-05	-7.0	-7.2	5.7e-13	0.69	0.03	0.97	FALSE
11	GTEx	Breast Mammary Tissue (Male)	CDC16	0.23	0.08	enet	11	0.09	3.8e-03	-6.7	-7.2	5.7e-13	0.72	0.03	0.85	FALSE
46	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CDC16	0.11	0.09	blup	49	0.09	1.8e-04	-6.8	-7.2	6.4e-13	0.73	0.03	0.94	FALSE
29	GTEx	Skin Sun Exposed Lower leg	CDC16	0.31	0.33	lasso	7	0.33	4.1e-28	-6.8	-7.2	7.0e-13	0.74	0.03	0.97	FALSE
44	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CDC16	0.04	0.01	blup	49	0.03	7.7e-03	-6.9	-7.1	1.3e-12	0.69	0.03	0.90	FALSE
10	GTEx	Breast Mammary Tissue	CDC16	0.25	0.28	lasso	6	0.26	6.9e-14	-6.9	-7.1	1.6e-12	0.70	0.03	0.97	FALSE
36	METSIM	Adipose	CDC16	0.18	0.27	enet	18	0.26	6.6e-39	-7.0	-7.0	1.8e-12	0.67	0.02	0.98	FALSE
15	GTEx	Cells Transformed fibroblasts	CDC16	0.17	0.13	lasso	6	0.15	4.6e-11	-6.8	-7.0	2.3e-12	0.76	0.03	0.97	FALSE
4	GTEx	Artery Aorta	CDC16	0.15	0.18	enet	10	0.17	1.6e-09	-6.9	-7.0	2.9e-12	0.71	0.03	0.97	FALSE
19	GTEx	Esophagus Gastroesophageal Junction	CDC16	0.09	0.05	lasso	2	0.02	5.7e-02	-6.9	-7.0	3.1e-12	0.73	0.03	0.85	FALSE
28	GTEx	Skin Not Sun Exposed Suprapubic	CDC16	0.35	0.42	enet	33	0.45	7.9e-27	-6.8	-7.0	3.6e-12	0.78	0.03	0.97	FALSE
26	GTEx	Pancreas	CDC16	0.09	0.14	lasso	3	0.06	1.8e-03	-7.0	-6.9	3.7e-12	0.72	0.02	0.94	FALSE
37	NTR	Blood	CDC16	0.10	0.20	bslmm	209	0.20	3.1e-63	-6.9	-6.9	4.1e-12	0.72	0.03	0.97	FALSE
42	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CDC16	0.05	0.08	lasso	4	0.08	7.2e-09	-6.9	-6.9	4.3e-12	0.69	0.03	0.97	FALSE
27	GTEx	Prostate	CDC16	0.17	0.16	lasso	3	0.11	1.4e-03	-6.9	-6.9	4.4e-12	0.72	0.03	0.88	FALSE
31	GTEx	Spleen	CDC16	0.25	0.19	lasso	7	0.21	4.9e-06	-6.9	-6.9	4.4e-12	0.71	0.04	0.94	FALSE
20	GTEx	Esophagus Gastroesophageal Junction	UPF3A	0.20	0.07	lasso	6	0.06	4.5e-03	-6.8	-6.9	4.5e-12	0.72	0.03	0.89	FALSE
7	GTEx	Brain Cerebellar Hemisphere	CDC16	0.17	0.10	lasso	9	0.17	3.5e-05	-6.8	-6.9	5.2e-12	0.56	0.04	0.93	FALSE
23	GTEx	Lung	CDC16	0.16	0.21	lasso	5	0.19	9.6e-15	-6.8	-6.9	5.8e-12	0.71	0.03	0.97	FALSE
34	GTEx	Thyroid	CDC16	0.12	0.13	lasso	2	0.11	8.2e-09	-6.8	-6.9	7.2e-12	0.72	0.03	0.97	FALSE
21	GTEx	Esophagus Mucosa	CDC16	0.35	0.46	lasso	6	0.46	1.0e-33	-6.9	-6.9	7.3e-12	0.73	0.03	0.97	FALSE
38	YFS	Blood	CDC16	0.28	0.54	enet	30	0.55	1.1e-220	-6.9	-6.8	7.8e-12	0.72	0.03	0.97	FALSE
6	GTEx	Artery Tibial	CDC16	0.23	0.26	lasso	8	0.25	2.8e-19	-6.8	-6.8	8.4e-12	0.72	0.03	0.97	FALSE
35	GTEx	Whole Blood	CDC16	0.31	0.20	lasso	5	0.20	4.4e-18	-6.8	-6.8	8.8e-12	0.69	0.03	0.97	FALSE
43	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CDC16	0.05	0.04	blup	49	0.05	2.0e-06	-6.8	-6.8	9.8e-12	0.82	0.02	0.98	FALSE
2	GTEx	Adipose Subcutaneous	CDC16	0.17	0.17	lasso	4	0.19	3.6e-15	-6.8	-6.8	9.9e-12	0.73	0.03	0.97	FALSE
33	GTEx	Testis	CDC16	0.32	0.30	enet	26	0.35	4.4e-16	-6.9	-6.8	1.0e-11	0.68	0.03	0.97	FALSE
14	GTEx	Cells EBV-transformed lymphocytes	CDC16	0.14	0.09	lasso	3	0.10	2.9e-04	-6.8	-6.8	1.2e-11	0.72	0.03	0.95	FALSE
24	GTEx	Muscle Skeletal	CDC16	0.05	0.06	lasso	1	0.05	9.2e-06	-6.8	-6.8	1.2e-11	0.72	0.03	0.96	FALSE
39	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CDC16	0.08	0.11	lasso	5	0.12	4.3e-10	-7.0	-6.8	1.3e-11	0.71	0.03	0.97	FALSE
5	GTEx	Artery Coronary	CDC16	0.41	0.02	enet	5	0.02	6.9e-02	-5.9	-6.7	2.2e-11	0.67	0.04	0.90	FALSE
40	The Cancer Genome Atlas	Breast Invasive Carcinoma	CDC16	0.01	0.01	blup	49	0.01	1.1e-03	-6.8	-6.6	3.7e-11	0.65	0.03	0.91	FALSE
16	GTEx	Colon Sigmoid	UPF3A	0.15	0.10	lasso	8	0.08	8.3e-04	-6.9	-6.6	3.9e-11	0.70	0.03	0.94	FALSE
32	GTEx	Stomach	CDC16	0.12	0.06	enet	23	0.08	1.6e-04	-6.9	-6.6	4.0e-11	0.73	0.04	0.96	FALSE
13	GTEx	Breast Mammary Tissue (Female)	UPF3A	0.32	0.16	lasso	13	0.17	1.2e-05	-6.9	-6.5	7.4e-11	0.71	0.04	0.96	FALSE
45	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CDC16	0.03	0.04	lasso	3	0.04	1.3e-05	-5.4	-6.5	8.3e-11	0.69	0.03	0.96	FALSE
8	GTEx	Brain Cerebellum	CDC16	0.18	0.05	lasso	4	0.07	3.4e-03	-6.8	-6.2	4.2e-10	0.70	0.04	0.91	FALSE
12	GTEx	Breast Mammary Tissue (Female)	CDC16	0.25	0.22	enet	28	0.22	3.6e-07	-6.9	-6.2	4.2e-10	0.69	0.03	0.96	FALSE
30	GTEx	Small Intestine Terminal Ileum	CDC16	0.16	0.04	lasso	9	0.03	6.1e-02	-7.0	-6.1	1.0e-09	0.59	0.04	0.62	FALSE
9	GTEx	Brain Cortex	UPF3A	0.25	0.11	enet	13	0.10	1.2e-03	-7.0	5.9	4.5e-09	-0.79	0.02	0.82	FALSE
47	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CDC16	0.07	0.03	blup	49	0.05	6.3e-03	-7.0	-5.9	4.5e-09	0.65	0.02	0.75	FALSE
22	GTEx	Esophagus Muscularis	CDC16	0.12	0.09	lasso	6	0.13	3.2e-08	-5.5	-5.6	1.6e-08	0.57	0.04	0.96	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CDC16	0.05	0.03	bslmm	208	0.04	2.4e-05	-6.9	-5.4	7.2e-08	0.66	0.03	0.97	FALSE
18	GTEx	Colon Transverse	UPF3A	0.13	0.04	lasso	3	0.04	5.6e-03	-3.3	-5.2	2.0e-07	0.68	0.06	0.84	FALSE