Best TWAS P=5.08e-12 · Best GWAS P=5.01e-21 conditioned to 1.14e-10
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | GPC5 | 0.28 | 0.18 | bslmm | 1091 | 0.27 | 6.6e-33 | 7.7 | 6.9 | 5.1e-12 | 0.67 | 0.90 | 0.10 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | GPC5 | 0.26 | 0.08 | enet | 65 | 0.12 | 1.4e-14 | 7.7 | 6.1 | 9.4e-10 | 0.60 | 0.34 | 0.66 | FALSE |