[Hub]/) : Traits : Comparative height size at age 10 :

chr16:80,779,331-82,901,701

Best TWAS P=1.82e-12 · Best GWAS P=7.61e-13 conditioned to 1.28e-12

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MPHOSPH6 0.30 0.24 lasso 8 0.23 2.1e-27 6.1 -5.4 5.6e-08 -0.04 0.04 0.96 FALSE
2 GTEx Adipose Subcutaneous MPHOSPH6 0.15 0.08 enet 8 0.09 5.1e-08 6.3 5.9 2.9e-09 0.00 0.01 0.99 FALSE
3 GTEx Adipose Visceral Omentum MPHOSPH6 0.32 0.14 lasso 4 0.17 3.5e-09 6.1 6.4 2.1e-10 0.02 0.01 0.99 FALSE
4 GTEx Adrenal Gland MPHOSPH6 0.34 0.25 lasso 3 0.26 8.4e-10 6.5 6.0 1.5e-09 0.02 0.00 1.00 FALSE
5 GTEx Artery Aorta MPHOSPH6 0.32 0.15 lasso 6 0.17 7.8e-10 6.3 6.2 7.8e-10 0.03 0.01 0.99 FALSE
6 GTEx Artery Tibial MPHOSPH6 0.36 0.24 enet 9 0.27 1.9e-21 6.3 6.4 1.4e-10 0.01 0.01 0.99 FALSE
7 GTEx Brain Cerebellar Hemisphere MPHOSPH6 0.49 0.30 enet 12 0.31 8.5e-09 6.5 6.3 2.7e-10 0.01 0.00 0.99 FALSE
8 GTEx Brain Cerebellum MPHOSPH6 0.40 0.36 enet 10 0.39 1.8e-12 5.1 6.0 1.8e-09 0.00 0.01 0.99 FALSE
9 GTEx Cells Transformed fibroblasts CMIP 0.20 0.05 lasso 6 0.07 1.0e-05 -3.4 -5.4 5.4e-08 -0.04 0.98 0.00 FALSE
10 GTEx Colon Transverse MPHOSPH6 0.21 0.16 lasso 3 0.17 1.4e-08 6.3 6.4 1.4e-10 0.02 0.01 0.99 FALSE
11 GTEx Esophagus Muscularis MPHOSPH6 0.36 0.23 lasso 7 0.20 1.7e-12 6.3 6.4 1.8e-10 0.01 0.01 0.99 FALSE
12 GTEx Heart Atrial Appendage MPHOSPH6 0.33 0.19 enet 27 0.21 5.4e-10 6.3 5.9 3.7e-09 0.01 0.01 0.99 FALSE
13 GTEx Heart Left Ventricle MPHOSPH6 0.28 0.24 lasso 3 0.24 8.9e-13 6.3 6.4 1.2e-10 0.01 0.00 1.00 FALSE
14 GTEx Lung MPHOSPH6 0.16 0.10 lasso 4 0.11 8.3e-09 6.5 6.4 1.5e-10 0.02 0.00 1.00 FALSE
15 GTEx Muscle Skeletal MPHOSPH6 0.27 0.19 lasso 7 0.23 1.4e-22 6.5 6.4 1.6e-10 0.02 0.00 1.00 FALSE
16 GTEx Nerve Tibial MPHOSPH6 0.40 0.22 lasso 7 0.28 1.0e-19 6.3 6.2 6.8e-10 0.01 0.01 0.99 FALSE
17 GTEx Pancreas MPHOSPH6 0.25 0.14 enet 15 0.15 9.2e-07 6.3 7.0 1.8e-12 0.01 0.01 0.99 TRUE
18 GTEx Stomach MPHOSPH6 0.41 0.10 lasso 7 0.09 3.5e-05 5.8 6.3 3.6e-10 0.02 0.01 0.99 FALSE
19 GTEx Testis MPHOSPH6 0.52 0.32 lasso 11 0.35 2.0e-16 6.3 6.0 2.3e-09 0.01 0.01 0.99 FALSE
20 GTEx Thyroid MPHOSPH6 0.31 0.21 lasso 4 0.26 4.7e-20 6.1 6.4 1.2e-10 0.02 0.01 0.99 FALSE
21 METSIM Adipose MPHOSPH6 0.12 0.07 bslmm 741 0.08 2.0e-11 6.4 5.4 7.7e-08 0.00 0.00 1.00 FALSE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MPHOSPH6 0.14 0.15 lasso 6 0.15 7.0e-17 6.1 5.9 3.0e-09 0.03 0.03 0.97 FALSE
23 The Cancer Genome Atlas Lung Adenocarcinoma MPHOSPH6 0.04 0.01 blup 90 0.02 2.2e-03 4.9 5.1 2.8e-07 0.04 0.04 0.51 FALSE
24 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma MPHOSPH6 0.13 0.09 lasso 2 0.12 2.4e-05 4.9 5.8 6.3e-09 0.02 0.02 0.92 FALSE
25 The Cancer Genome Atlas Prostate Adenocarcinoma MPHOSPH6 0.07 0.03 lasso 4 0.06 8.0e-07 6.5 5.2 1.9e-07 -0.03 0.01 0.98 FALSE
26 The Cancer Genome Atlas Thyroid Carcinoma MPHOSPH6 0.18 0.16 lasso 3 0.16 5.1e-15 6.5 6.5 6.3e-11 0.01 0.00 1.00 FALSE