Best TWAS P=3.13e-10 · Best GWAS P=1.9e-09 conditioned to 0.635
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | ZFP1 | 0.38 | 0.21 | lasso | 5 | 0.21 | 5.6e-11 | -6.0 | 6.2 | 7.3e-10 | -0.97 | 0.00 | 1.00 | FALSE |
| 2 | GTEx | Adrenal Gland | ZFP1 | 0.53 | 0.28 | enet | 30 | 0.30 | 1.7e-11 | -6.0 | 5.6 | 2.6e-08 | -0.84 | 0.00 | 1.00 | FALSE |
| 3 | GTEx | Artery Aorta | ZFP1 | 0.28 | 0.14 | enet | 13 | 0.19 | 1.0e-10 | -5.7 | 6.3 | 3.1e-10 | -0.92 | 0.00 | 1.00 | TRUE |
| 4 | GTEx | Breast Mammary Tissue | ZFP1 | 0.21 | 0.18 | lasso | 2 | 0.17 | 7.0e-09 | -6.0 | 6.2 | 5.8e-10 | -0.98 | 0.00 | 1.00 | FALSE |
| 5 | GTEx | Breast Mammary Tissue (Male) | ZFP1 | 0.23 | 0.24 | lasso | 3 | 0.22 | 7.8e-06 | -5.6 | 5.6 | 2.2e-08 | -0.81 | 0.02 | 0.93 | FALSE |
| 6 | GTEx | Heart Atrial Appendage | ZFP1 | 0.23 | 0.15 | lasso | 2 | 0.14 | 9.1e-07 | -6.0 | 6.0 | 2.7e-09 | -1.00 | 0.00 | 1.00 | FALSE |
| 7 | GTEx | Heart Left Ventricle | ZFP1 | 0.37 | 0.20 | lasso | 8 | 0.19 | 1.4e-10 | -5.8 | 5.8 | 7.7e-09 | -0.90 | 0.00 | 1.00 | FALSE |
| 8 | GTEx | Muscle Skeletal | ZFP1 | 0.27 | 0.08 | enet | 31 | 0.11 | 3.1e-11 | -6.0 | 5.9 | 3.5e-09 | -0.81 | 0.00 | 1.00 | FALSE |
| 9 | GTEx | Nerve Tibial | ZFP1 | 0.41 | 0.23 | enet | 17 | 0.25 | 8.6e-18 | -6.0 | 5.5 | 4.8e-08 | -0.93 | 0.00 | 1.00 | FALSE |
| 10 | GTEx | Skin Not Sun Exposed Suprapubic | ZFP1 | 0.33 | 0.15 | lasso | 10 | 0.16 | 2.8e-09 | -5.7 | 5.5 | 3.7e-08 | -0.95 | 0.00 | 1.00 | FALSE |
| 11 | GTEx | Testis | ZFP1 | 0.17 | 0.14 | lasso | 3 | 0.12 | 4.5e-06 | -5.9 | 6.0 | 1.5e-09 | -0.98 | 0.00 | 1.00 | FALSE |
| 12 | GTEx | Thyroid | ZFP1 | 0.27 | 0.16 | enet | 17 | 0.18 | 1.3e-13 | -6.0 | 5.9 | 4.5e-09 | -0.93 | 0.00 | 1.00 | FALSE |
| 13 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ZFP1 | 0.08 | 0.10 | lasso | 3 | 0.10 | 2.5e-20 | -5.8 | 6.0 | 2.5e-09 | -0.99 | 0.00 | 1.00 | FALSE |
| 14 | The Cancer Genome Atlas | Colon Adenocarcinoma | ZFP1 | 0.22 | 0.09 | lasso | 6 | 0.12 | 3.3e-07 | -5.7 | 5.3 | 1.1e-07 | -0.86 | 0.01 | 0.99 | FALSE |
| 15 | The Cancer Genome Atlas | Esophageal Carcinoma | ZFP1 | 0.19 | 0.01 | blup | 63 | 0.06 | 6.9e-03 | -2.4 | 5.1 | 2.9e-07 | -0.58 | 0.01 | 0.52 | FALSE |
| 16 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | TMEM170A | 0.08 | 0.10 | blup | 36 | 0.13 | 9.1e-08 | -4.9 | -5.5 | 3.7e-08 | 0.08 | 0.01 | 0.98 | TRUE |
| 17 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ZFP1 | 0.15 | 0.12 | lasso | 6 | 0.13 | 2.7e-14 | -5.2 | 5.7 | 1.6e-08 | -0.86 | 0.05 | 0.95 | FALSE |
| 18 | The Cancer Genome Atlas | Lung Adenocarcinoma | ZFP1 | 0.20 | 0.07 | enet | 11 | 0.14 | 1.3e-16 | -6.0 | 5.5 | 3.2e-08 | -0.85 | 0.00 | 1.00 | FALSE |
| 19 | The Cancer Genome Atlas | Prostate Adenocarcinoma | ZFP1 | 0.10 | 0.09 | blup | 63 | 0.08 | 2.2e-08 | -6.0 | 5.2 | 2.3e-07 | -0.89 | 0.00 | 1.00 | FALSE |