Best TWAS P=2.18e-10 · Best GWAS P=1.68e-17 conditioned to 9.8e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | KCNJ15 | 0.05 | 0.03 | lasso | 5 | 0.02 | 6.8e-04 | -6.0 | 6.3 | 2.2e-10 | -0.67 | 0.62 | 0.33 | TRUE |
| 2 | NTR | Blood | KCNJ15 | 0.06 | 0.09 | lasso | 4 | 0.09 | 7.0e-27 | -5.8 | 5.9 | 4.2e-09 | -0.68 | 1.00 | 0.00 | FALSE |
| 3 | YFS | Blood | KCNJ15 | 0.22 | 0.29 | enet | 19 | 0.30 | 3.9e-100 | -6.0 | 6.1 | 1.1e-09 | -0.69 | 1.00 | 0.00 | FALSE |
| 4 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | DSCR10 | 0.07 | 0.03 | blup | 35 | 0.06 | 3.0e-03 | 5.1 | -6.1 | 1.3e-09 | 0.71 | 0.02 | 0.67 | FALSE |