Best TWAS P=1.08e-07 · Best GWAS P=2.53e-08 conditioned to 0.0912
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellum | CCDC116 | 0.25 | 0.16 | lasso | 4 | 0.10 | 6.5e-04 | -4.8 | 5.3 | 1.1e-07 | -0.26 | 0.26 | 0.51 | TRUE |
| 2 | GTEx | Brain Nucleus accumbens basal ganglia | LL22NC03-86G7.1 | 0.61 | 0.50 | enet | 32 | 0.56 | 7.3e-18 | 4.3 | -5.2 | 2.1e-07 | 0.92 | 0.02 | 0.97 | TRUE |
| 3 | METSIM | Adipose | YDJC | 0.05 | 0.04 | enet | 11 | 0.04 | 7.7e-07 | -4.7 | -5.3 | 1.1e-07 | 0.37 | 0.41 | 0.57 | FALSE |
| 4 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | CCDC116 | 0.03 | 0.02 | enet | 12 | 0.02 | 5.1e-03 | -4.6 | 5.2 | 2.3e-07 | -0.26 | 0.01 | 0.63 | FALSE |
| 5 | The Cancer Genome Atlas | Glioblastoma Multiforme | CCDC116 | 0.10 | 0.06 | blup | 39 | 0.07 | 4.4e-03 | -4.6 | 5.1 | 2.9e-07 | -0.21 | 0.01 | 0.73 | FALSE |