[Hub]/) : Traits : Comparative height size at age 10 : ← →

chr2:113,270,599-114,735,416

Best TWAS P=1.97e-09 · Best GWAS P=2.48e-08 conditioned to 0.0548

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	LOC654433	0.48	0.47	enet	29	0.51	5.5e-72	4.6	-5.2	1.6e-07	-0.58	0.26	0.72	FALSE
2	GTEx	Adrenal Gland	PAX8	0.37	0.12	enet	23	0.14	8.0e-06	-5.2	-5.6	2.2e-08	-0.59	0.03	0.96	FALSE
3	GTEx	Artery Aorta	PAX8	0.39	0.40	enet	18	0.41	2.4e-24	4.6	-5.3	9.2e-08	-0.51	0.26	0.72	FALSE
4	GTEx	Artery Aorta	AC016683.6	0.50	0.45	lasso	10	0.48	2.2e-29	4.6	-5.2	1.9e-07	-0.50	0.26	0.72	FALSE
5	GTEx	Artery Coronary	PAX8	0.29	0.16	enet	26	0.07	2.7e-03	-4.2	-5.8	5.7e-09	-0.61	0.02	0.96	FALSE
6	GTEx	Artery Coronary	AC016683.6	0.50	0.24	enet	33	0.29	3.2e-10	4.6	-5.6	2.2e-08	-0.54	0.07	0.93	FALSE
7	GTEx	Artery Tibial	AC016683.6	0.46	0.34	enet	31	0.35	1.7e-28	4.6	-5.5	5.0e-08	-0.51	0.26	0.72	FALSE
8	GTEx	Brain Frontal Cortex BA9	AC016683.6	0.38	0.26	lasso	9	0.22	1.3e-06	4.6	-5.5	4.7e-08	-0.57	0.06	0.86	FALSE
9	GTEx	Brain Hypothalamus	PAX8	0.35	0.24	enet	26	0.20	1.9e-05	4.6	-5.2	2.0e-07	-0.40	0.13	0.46	FALSE
10	GTEx	Breast Mammary Tissue	PAX8	0.23	0.17	lasso	6	0.21	3.8e-11	4.6	-5.3	1.5e-07	-0.61	0.08	0.92	FALSE
11	GTEx	Breast Mammary Tissue (Female)	AC016683.6	0.30	0.24	lasso	5	0.34	6.1e-11	4.6	-5.3	1.4e-07	-0.56	0.03	0.96	FALSE
12	GTEx	Cells Transformed fibroblasts	PAX8	0.32	0.30	enet	14	0.32	5.2e-25	4.6	-5.5	4.7e-08	-0.62	0.26	0.72	FALSE
13	GTEx	Esophagus Gastroesophageal Junction	AC016683.6	0.41	0.27	enet	17	0.28	1.6e-10	4.6	-5.3	1.2e-07	-0.51	0.23	0.75	FALSE
14	GTEx	Esophagus Muscularis	PAX8	0.40	0.26	lasso	13	0.37	6.7e-24	4.2	-6.0	2.2e-09	-0.73	0.04	0.96	FALSE
15	GTEx	Esophagus Muscularis	AC016683.6	0.43	0.24	lasso	8	0.34	3.6e-21	4.6	-5.6	2.8e-08	-0.72	0.11	0.89	FALSE
16	GTEx	Heart Left Ventricle	PAX8	0.08	0.06	enet	13	0.07	8.5e-05	4.6	-5.3	1.2e-07	-0.62	0.13	0.77	FALSE
17	GTEx	Heart Left Ventricle	AC016683.6	0.41	0.30	enet	25	0.43	1.1e-24	4.6	-5.4	7.6e-08	-0.66	0.08	0.91	FALSE
18	GTEx	Liver	AC016683.6	0.36	0.36	enet	10	0.36	7.7e-11	4.6	-5.5	3.6e-08	-0.63	0.14	0.85	FALSE
19	GTEx	Muscle Skeletal	AC016683.6	0.45	0.30	enet	48	0.34	5.0e-35	4.6	-5.2	2.6e-07	-0.52	0.26	0.72	FALSE
20	GTEx	Nerve Tibial	PAX8	0.40	0.37	enet	16	0.40	4.0e-30	4.6	-5.2	1.6e-07	-0.59	0.26	0.72	FALSE
21	GTEx	Nerve Tibial	AC016683.6	0.43	0.38	lasso	8	0.41	3.2e-31	4.6	-5.2	2.5e-07	-0.57	0.26	0.72	FALSE
22	GTEx	Prostate	AC016683.6	0.40	0.25	lasso	5	0.27	2.2e-07	-5.2	-5.2	2.5e-07	-0.61	0.03	0.97	FALSE
23	GTEx	Skin Not Sun Exposed Suprapubic	PAX8	0.31	0.28	lasso	4	0.34	1.3e-19	4.6	-5.2	1.5e-07	-0.56	0.12	0.87	FALSE
24	GTEx	Skin Not Sun Exposed Suprapubic	AC016683.6	0.34	0.34	lasso	7	0.37	1.7e-21	4.6	-5.3	1.0e-07	-0.57	0.23	0.75	FALSE
25	GTEx	Skin Sun Exposed Lower leg	PAX8	0.41	0.31	enet	14	0.35	1.0e-29	-5.2	-5.5	4.1e-08	-0.61	0.02	0.98	FALSE
26	GTEx	Skin Sun Exposed Lower leg	AC016683.6	0.49	0.27	lasso	6	0.36	8.8e-31	4.6	-5.2	1.7e-07	-0.56	0.15	0.84	FALSE
27	GTEx	Spleen	AC016683.6	0.47	0.43	lasso	8	0.38	8.5e-11	4.6	-5.3	8.8e-08	-0.52	0.20	0.78	FALSE
28	GTEx	Stomach	PAX8	0.22	0.09	lasso	11	0.09	5.6e-05	-5.2	-5.4	8.2e-08	-0.62	0.06	0.90	FALSE
29	ROSMAP	Brain Pre-frontal Cortex	AC016683.6	0.52	0.45	enet	26	0.49	9.3e-72	4.6	-5.2	2.3e-07	-0.58	0.26	0.72	FALSE
30	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PAX8	0.08	0.03	blup	77	0.05	8.4e-05	4.6	-5.2	2.7e-07	-0.59	0.04	0.93	FALSE
31	The Cancer Genome Atlas	Colon Adenocarcinoma	LOC654433	0.25	0.18	blup	60	0.20	1.2e-11	4.6	-5.2	2.6e-07	-0.55	0.15	0.84	FALSE
32	The Cancer Genome Atlas	Esophageal Carcinoma	LOC654433	0.24	0.16	enet	10	0.07	2.5e-03	-5.2	-5.5	2.9e-08	-0.62	0.02	0.96	FALSE
33	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	LOC654433	0.24	0.32	lasso	4	0.34	1.6e-39	4.6	-5.2	2.1e-07	-0.57	0.26	0.72	FALSE
34	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PAX8	0.12	0.05	enet	11	0.07	3.5e-04	-5.2	-5.5	3.2e-08	-0.63	0.02	0.93	FALSE
35	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LOC654433	0.08	0.12	blup	60	0.09	8.9e-07	-5.2	-5.9	3.9e-09	-0.74	0.02	0.98	FALSE
36	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	LOC654433	0.18	0.11	blup	60	0.16	2.7e-07	4.6	-6.0	2.0e-09	-0.70	0.05	0.94	TRUE
37	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	PAX8	0.14	0.12	enet	15	0.13	5.8e-06	4.6	-5.5	4.4e-08	-0.56	0.15	0.78	FALSE
38	The Cancer Genome Atlas	Soft Tissue Sarcoma	LOC654433	0.26	0.20	lasso	6	0.19	1.7e-11	4.6	-5.2	1.5e-07	-0.57	0.24	0.75	FALSE
39	The Cancer Genome Atlas	Testicular Germ Cell Tumors	LOC654433	0.22	0.01	blup	60	0.09	3.4e-04	-4.2	-5.2	1.6e-07	-0.69	0.03	0.90	FALSE