[Hub]/) : Traits : Comparative height size at age 10 :

chr4:16,922,182-18,507,692

Best TWAS P=1.57e-65 · Best GWAS P=5.76e-57 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MED28 0.07 0.09 enet 9 0.11 7.1e-13 -4.9 5.3 1.1e-07 -0.18 1.00 0.00 TRUE
2 GTEx Adipose Subcutaneous DCAF16 0.21 0.15 lasso 3 0.17 5.1e-14 11.3 11.1 7.3e-29 -0.23 1.00 0.00 FALSE
3 GTEx Adipose Visceral Omentum DCAF16 0.19 0.06 enet 10 0.11 3.9e-06 11.3 12.3 8.6e-35 -0.34 0.37 0.32 FALSE
4 GTEx Artery Aorta DCAF16 0.10 0.01 enet 6 0.02 4.7e-02 -14.7 17.1 1.6e-65 -0.79 0.08 0.64 TRUE
5 GTEx Artery Tibial DCAF16 0.16 0.16 lasso 5 0.13 1.5e-10 12.2 13.7 2.0e-42 -0.35 1.00 0.00 FALSE
6 GTEx Breast Mammary Tissue DCAF16 0.12 0.08 lasso 4 0.10 6.4e-06 11.4 13.6 6.6e-42 -0.51 0.09 0.77 FALSE
7 GTEx Breast Mammary Tissue (Male) DCAF16 0.24 0.03 enet 18 -0.01 4.4e-01 -14.3 15.6 4.0e-55 -0.75 0.03 0.67 FALSE
8 GTEx Breast Mammary Tissue (Female) DCAF16 0.16 0.13 lasso 2 0.06 7.8e-03 11.3 11.3 1.8e-29 -0.26 0.06 0.10 FALSE
9 GTEx Esophagus Mucosa DCAF16 0.10 0.02 lasso 4 0.02 8.3e-03 11.4 12.4 4.0e-35 -0.35 0.14 0.36 FALSE
10 GTEx Esophagus Muscularis DCAF16 0.16 0.14 lasso 3 0.14 9.3e-09 11.3 11.3 1.7e-29 -0.25 0.99 0.00 FALSE
11 GTEx Nerve Tibial DCAF16 0.16 0.14 lasso 3 0.14 2.8e-10 11.3 12.4 3.3e-35 -0.35 0.99 0.00 FALSE
12 GTEx Pituitary DCAF16 0.27 0.20 enet 15 0.19 1.3e-05 11.3 10.7 5.9e-27 -0.37 0.08 0.24 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic DCAF16 0.16 0.08 lasso 5 0.12 4.4e-07 11.2 12.2 4.1e-34 -0.34 0.63 0.05 FALSE
14 GTEx Skin Sun Exposed Lower leg DCAF16 0.14 0.12 enet 14 0.12 5.4e-10 11.4 12.4 4.2e-35 -0.27 1.00 0.00 FALSE
15 GTEx Spleen DCAF16 0.35 0.02 lasso 5 0.11 8.5e-04 11.3 16.3 6.2e-60 -0.65 0.05 0.61 TRUE
16 GTEx Stomach DCAF16 0.21 0.04 lasso 6 0.02 5.6e-02 12.2 13.8 3.7e-43 -0.24 0.19 0.05 FALSE
17 GTEx Thyroid DCAF16 0.11 0.02 lasso 5 0.03 2.3e-03 11.3 15.5 1.7e-54 -0.53 0.23 0.60 TRUE
18 ROSMAP Brain Pre-frontal Cortex FAM184B 0.17 0.14 enet 31 0.18 5.1e-23 -4.9 -7.4 1.6e-13 0.25 1.00 0.00 TRUE
19 ROSMAP Brain Pre-frontal Cortex MED28 0.02 0.01 bslmm 411 0.00 1.9e-01 -4.9 6.7 1.9e-11 -0.29 0.22 0.03 FALSE
20 ROSMAP Brain Pre-frontal Cortex DCAF16 0.04 0.02 bslmm 379 0.01 3.9e-02 -14.3 14.4 7.9e-47 -0.83 0.03 0.88 FALSE
21 YFS Blood DCAF16 0.02 0.02 lasso 1 0.01 1.1e-04 12.2 12.2 1.8e-34 -0.25 0.84 0.03 FALSE
22 The Cancer Genome Atlas Colon Adenocarcinoma NCAPG 0.08 0.04 blup 34 0.09 1.1e-05 -14.2 -12.1 1.1e-33 0.83 0.04 0.93 FALSE
23 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NCAPG 0.14 0.07 lasso 3 0.07 5.2e-08 -14.3 -13.9 9.3e-44 0.83 0.87 0.12 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma DCAF16 0.09 0.02 lasso 3 0.04 5.2e-05 12.2 16.5 2.0e-61 -0.63 0.02 0.95 FALSE
25 The Cancer Genome Atlas Brain Lower Grade Glioma NCAPG 0.02 0.03 lasso 1 0.02 9.0e-04 -14.2 -14.2 1.4e-45 0.86 0.03 0.54 TRUE
26 The Cancer Genome Atlas Lung Adenocarcinoma NCAPG 0.06 0.02 blup 34 0.04 1.0e-05 -14.2 -8.4 4.3e-17 0.67 0.11 0.20 FALSE
27 The Cancer Genome Atlas Pancreatic Adenocarcinoma MED28 0.10 0.12 enet 8 0.12 1.6e-05 -5.3 5.2 2.2e-07 -0.12 0.01 0.96 TRUE
28 The Cancer Genome Atlas Prostate Adenocarcinoma DCAF16 0.04 0.04 blup 31 0.04 2.2e-05 11.3 14.9 2.6e-50 -0.56 0.23 0.34 FALSE
29 The Cancer Genome Atlas Prostate Adenocarcinoma NCAPG 0.02 0.02 blup 34 0.02 3.4e-03 -12.9 -11.6 5.3e-31 0.75 0.01 0.87 FALSE
30 The Cancer Genome Atlas Thyroid Carcinoma DCAF16 0.07 0.04 blup 31 0.07 4.9e-07 12.2 16.0 7.3e-58 -0.64 0.16 0.76 FALSE