Best TWAS P=5.46e-10 · Best GWAS P=9.42e-11 conditioned to 0.0324
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | CDO1 | 0.12 | 0.04 | lasso | 6 | 0.05 | 7.0e-05 | 6 | -5.7 | 9.9e-09 | -0.81 | 0.04 | 0.96 | FALSE |
2 | GTEx | Artery Aorta | CDO1 | 0.27 | 0.15 | enet | 16 | 0.15 | 1.7e-08 | 6 | -5.5 | 4.0e-08 | -0.85 | 0.04 | 0.96 | FALSE |
3 | GTEx | Artery Tibial | CDO1 | 0.24 | 0.15 | lasso | 6 | 0.12 | 5.3e-10 | 6 | -6.2 | 5.5e-10 | -0.88 | 0.02 | 0.98 | TRUE |