TWAS
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Genes
Traits
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Traits
:
Comparative height size at age 10
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chr6:44,079,216-46,043,561
Best TWAS P=5.52e-10 · Best GWAS P=1.16e-11 conditioned to 0.00396
44M
44.5M
45M
45.5M
46M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Colon Adenocarcinoma
SUPT3H
0.08
0.01
blup
191
0.05
1.0e-03
4.4
-6.2
5.5e-10
0.85
0.02
0.94
TRUE
2
GTEx
Esophagus Muscularis
SUPT3H
0.10
0.03
enet
20
0.02
1.3e-02
-6.1
-6.1
8.0e-10
0.71
0.01
0.95
FALSE
1
GTEx
Esophagus Gastroesophageal Junction
SUPT3H
0.27
0.01
lasso
3
0.00
2.7e-01
-6.1
-5.8
5.0e-09
0.83
0.03
0.79
FALSE
3
GTEx
Thyroid
SUPT3H
0.29
0.07
lasso
8
0.07
7.3e-06
-4.5
-5.3
1.1e-07
0.52
0.91
0.03
FALSE