Best TWAS P=5.52e-10 · Best GWAS P=1.16e-11 conditioned to 0.00396
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | SUPT3H | 0.27 | 0.01 | lasso | 3 | 0.00 | 2.7e-01 | -6.1 | -5.8 | 5.0e-09 | 0.83 | 0.03 | 0.79 | FALSE |
| 2 | GTEx | Esophagus Muscularis | SUPT3H | 0.10 | 0.03 | enet | 20 | 0.02 | 1.3e-02 | -6.1 | -6.1 | 8.0e-10 | 0.71 | 0.01 | 0.95 | FALSE |
| 3 | GTEx | Thyroid | SUPT3H | 0.29 | 0.07 | lasso | 8 | 0.07 | 7.3e-06 | -4.5 | -5.3 | 1.1e-07 | 0.52 | 0.91 | 0.03 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | SUPT3H | 0.08 | 0.01 | blup | 191 | 0.05 | 1.0e-03 | 4.4 | -6.2 | 5.5e-10 | 0.85 | 0.02 | 0.94 | TRUE |