Best TWAS P=2.5e-09 · Best GWAS P=6.87e-10 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | UBXN2A | 0.22 | 0.18 | enet | 28 | 0.24 | 3.0e-28 | 4.6 | -5.4 | 8.6e-08 | -0.91 | 0.09 | 0.91 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | UBXN2A | 0.08 | 0.02 | lasso | 3 | 0.02 | 5.2e-02 | 5.9 | 6.0 | 2.5e-09 | 0.96 | 0.02 | 0.94 | TRUE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | UBXN2A | 0.03 | 0.01 | lasso | 4 | 0.02 | 2.2e-03 | 5.9 | -5.9 | 3.1e-09 | -0.82 | 0.02 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | UBXN2A | 0.04 | 0.04 | lasso | 1 | 0.03 | 1.4e-04 | 5.9 | -5.9 | 2.8e-09 | -0.97 | 0.01 | 0.98 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | UBXN2A | 0.05 | 0.00 | blup | 46 | 0.01 | 1.3e-02 | -1.6 | 5.6 | 2.2e-08 | 0.66 | 0.01 | 0.43 | FALSE |