[Hub]/) : Traits : Sensitivity / hurt feelings :

chr1:52,981,087-54,492,569

Best TWAS P=1.87e-09 · Best GWAS P=1.09e-08 conditioned to 0.574

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C1orf123 0.21 0.27 bslmm 483 0.28 6.4e-34 -5.6 5.4 6.4e-08 -0.83 0.02 0.98 FALSE
2 GTEx Muscle Skeletal C1orf123 0.07 0.06 lasso 5 0.06 8.9e-07 -5.6 5.6 1.9e-08 -0.82 0.02 0.98 FALSE
3 ROSMAP Brain Pre-frontal Cortex LRP8 0.07 0.04 lasso 3 0.04 3.0e-06 -5.5 5.9 4.2e-09 -0.94 0.01 0.98 FALSE
4 ROSMAP Brain Pre-frontal Cortex C1orf123 0.31 0.28 enet 14 0.34 3.2e-45 -5.1 5.4 5.8e-08 -0.81 0.02 0.98 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma C1orf123 0.03 0.03 blup 43 0.04 2.9e-08 -5.6 6.0 1.9e-09 -0.91 0.01 0.99 TRUE
6 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma C1orf123 0.05 0.05 blup 42 0.04 8.2e-06 -5.6 5.8 8.1e-09 -0.87 0.02 0.98 FALSE
7 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma C1orf123 0.10 0.08 lasso 2 0.08 3.5e-05 -5.7 5.7 1.1e-08 -0.96 0.02 0.98 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma C1orf123 0.03 0.03 lasso 4 0.03 5.4e-04 -5.1 5.2 1.5e-07 -0.87 0.02 0.93 FALSE
9 The Cancer Genome Atlas Lung Squamous Cell Carcinoma C1orf123 0.04 0.06 blup 43 0.06 2.2e-07 -5.1 5.5 3.3e-08 -0.91 0.03 0.97 FALSE
10 The Cancer Genome Atlas Pancreatic Adenocarcinoma C1orf123 0.07 0.06 lasso 4 0.02 4.0e-02 -5.6 5.6 1.9e-08 -0.82 0.01 0.69 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma C1orf123 0.11 0.07 lasso 4 0.06 2.8e-07 -5.6 5.5 3.6e-08 -0.87 0.02 0.98 FALSE
12 The Cancer Genome Atlas Testicular Germ Cell Tumors C1orf123 0.08 0.06 blup 43 0.05 8.3e-03 -5.7 5.3 1.2e-07 -0.92 0.01 0.70 FALSE
13 The Cancer Genome Atlas Testicular Germ Cell Tumors CPT2 0.10 0.05 blup 53 0.02 5.2e-02 -5.7 5.3 9.9e-08 -0.93 0.01 0.86 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma C1orf123 0.09 0.14 lasso 4 0.15 3.7e-14 -5.6 5.6 1.9e-08 -0.88 0.02 0.98 FALSE