Hub : Traits :

Sensitivity / hurt feelings

539 significantly associated models · 55 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	1	52981087	54492569	3	1	1.9e-09	1.1e-08	5.7e-01	99	C1orf123
2	2	147993969	149475737	1	1	3.1e-07	3.9e-08	9.4e-03	78	ORC4
3	7	125383444	127590914	1	1	4.9e-11	4.3e-14	1.9e-06	60	GRM8
4	8	8092025	9669775	6	1	1.4e-09	6.6e-09	1.3e-02	82	FAM86B3P
5	8	10056664	11860845	7	1	7.6e-12	7.5e-11	1.1e-01	94	XKR6
6	8	141421996	142253369	1	1	1.5e-07	4.4e-07	7.8e-01	100	PTK2
7	9	33056378	34496024	1	1	7.2e-08	1.1e-07	4.2e-03	71	PRSS3
8	9	95502571	96898436	1	1	9.2e-09	1.7e-08	4.9e-01	98	RP11-165J3.6
9	9	97520168	98975128	1	1	6.1e-12	1.6e-11	2.3e-01	97	PTCH1
10	11	112950782	113591832	3	4	7.4e-10	8.9e-09	NaN	NaN	ANKK1 DRD2 TTC12
11	12	109231851	110729807	4	1	1.2e-07	7.0e-08	1.0e+00	100	MMAB
12	14	69412804	69954376	1	1	2.1e-07	3.0e-07	5.4e-02	86	EXD2
13	15	90718541	92120170	2	1	3.8e-08	3.2e-08	1.0e+00	100	FURIN
14	17	17484654	18914778	1	1	8.3e-08	4.1e-06	4.5e-03	62	TOP3A
15	17	42413481	45796313	21	1	5.4e-23	1.6e-21	4.3e-01	99	PLEKHM1
16	19	18829733	20313262	1	1	8.3e-08	9.7e-07	9.0e-01	100	GATAD2A

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
Bipolar Disorder or Schizophrenia	3.6	3	1	2.2	0.00	1.0e+00	FAM86B3P FURIN GATAD2A
Depressed Affect (Nagel 2018)	11.5	12	6	13.3	0.98	3.6e-09	ANKK1 DRD2 EXD2 GRM8 MMAB ORC4 PLEKHM1 PTCH1 PTK2 RP11-165J3.6 TOP3A TTC12
Depression (Nagel 2018)	7.2	5	0	0.0	0.97	1.3e-03	ANKK1 PLEKHM1 RP11-165J3.6 TOP3A TTC12
Intelligence (Savage-Jansen 2018)	1.6	1	0	0.0	0.00	1.0e+00	PLEKHM1
Neuroticism (Nagel 2018)	16.5	14	11	24.4	0.98	3.2e-10	ANKK1 C1orf123 DRD2 EXD2 FURIN GRM8 MMAB ORC4 PLEKHM1 PTCH1 PTK2 RP11-165J3.6 TOP3A TTC12
Schizophrenia (2018)	3.9	2	1	2.2	0.00	1.0e+00	FURIN GATAD2A
Worry (Nagel 2018)	9.5	8	8	17.8	0.99	6.2e-07	ANKK1 DRD2 MMAB ORC4 PLEKHM1 PTCH1 RP11-165J3.6 TTC12
Verbal and Numeric Reasoning (VNR)	1.8	1	0	0.0	0.00	1.0e+00	PLEKHM1
Breast Cancer	3.3	3	2	4.4	0.00	1.0e+00	FURIN GATAD2A PLEKHM1
Ovarian Cancer	2.8	1	1	2.2	0.00	1.0e+00	PLEKHM1
HDL Cholesterol	2.5	1	1	2.2	0.00	1.0e+00	MMAB
Lupus	2.6	2	0	0.0	0.00	1.0e+00	FAM86B3P XKR6
Neuroticism (2016)	10.3	6	3	6.7	0.96	2.4e-03	ANKK1 DRD2 FAM86B3P PLEKHM1 TTC12 XKR6
Primary Biliary Cirrhosis	1.4	1	0	0.0	0.00	1.0e+00	PLEKHM1
Schizophrenia (2014)	4.5	4	2	4.4	0.58	4.2e-01	DRD2 FAM86B3P FURIN GATAD2A
Triglycerides	2.0	1	0	0.0	0.00	1.0e+00	GATAD2A
Blood Eosinophil Count	2.0	4	4	8.9	-0.08	9.2e-01	GATAD2A ORC4 PLEKHM1 TOP3A
Blood Platelet Count	1.3	2	1	2.2	0.00	1.0e+00	GATAD2A PTK2
Blood Red Count	2.7	3	1	2.2	0.00	1.0e+00	DRD2 EXD2 PLEKHM1
Blood White Count	1.1	4	2	4.4	-0.02	9.8e-01	FURIN PLEKHM1 PTCH1 TTC12
Heel T-Score	1.0	1	1	2.2	0.00	1.0e+00	PLEKHM1
BMI	1.5	4	1	2.2	1.00	4.6e-05	ANKK1 EXD2 MMAB TTC12
Height	1.0	5	4	8.9	0.53	3.6e-01	FURIN PLEKHM1 PTCH1 RP11-165J3.6 TOP3A
Waist Hip Ratio (WHR)	2.1	4	1	2.2	1.00	1.2e-03	ANKK1 PLEKHM1 PTK2 TTC12
Systolic Blood Pressure	3.5	5	3	6.7	-0.53	3.6e-01	FURIN MMAB PLEKHM1 PTK2 TOP3A
Smoking Status	1.7	1	0	0.0	0.00	1.0e+00	EXD2
Cardiovascular Disease	2.9	5	1	2.2	0.51	3.0e-01	ANKK1 DRD2 FURIN TOP3A TTC12
Lung FEV1/FVC ratio	2.1	3	1	2.2	0.00	1.0e+00	PLEKHM1 PTCH1 PTK2
Lung FVC	4.0	2	2	4.4	0.00	1.0e+00	PLEKHM1 PTCH1
Neuroticism	15.4	13	9	20.0	0.98	2.4e-09	ANKK1 DRD2 EXD2 FURIN GRM8 MMAB ORC4 PLEKHM1 PTCH1 PTK2 RP11-165J3.6 TOP3A TTC12
Hand grip strength (left)	1.7	1	1	2.2	0.00	1.0e+00	PLEKHM1
Number of treatments/medications taken	3.3	1	0	0.0	0.00	1.0e+00	TTC12
Frequency of depressed mood in last 2 weeks	6.9	4	0	0.0	1.00	4.2e-03	ANKK1 DRD2 PLEKHM1 RP11-165J3.6
Hearing difficulty/problems: Yes	3.5	2	1	2.2	0.00	1.0e+00	MMAB PTK2
Relative age of first facial hair	3.0	1	1	2.2	0.00	1.0e+00	PLEKHM1
Other serious medical condition/disability diagnosed by doctor	3.5	2	0	0.0	0.00	1.0e+00	ANKK1 TTC12
Systolic blood pressure, automated reading	4.0	4	4	8.9	-0.93	6.7e-02	FAM86B3P FURIN PLEKHM1 XKR6
Angina	1.9	1	1	2.2	0.00	1.0e+00	FURIN
Impedance of leg (right)	3.4	7	3	6.7	0.15	7.4e-01	FAM86B3P FURIN GATAD2A MMAB PLEKHM1 PTCH1 XKR6
Leg fat-free mass (left)	2.0	6	3	6.7	-0.07	8.9e-01	FAM86B3P FURIN GATAD2A MMAB PTCH1 XKR6
Trunk fat percentage	2.1	4	1	2.2	0.39	5.1e-01	ANKK1 EXD2 PLEKHM1 TTC12
Hand grip strength (right)	1.4	1	1	2.2	0.00	1.0e+00	PLEKHM1
Current tobacco smoking	3.7	1	0	0.0	0.00	1.0e+00	EXD2
Fed-up feelings	8.2	9	4	8.9	0.99	8.3e-07	ANKK1 DRD2 EXD2 FAM86B3P ORC4 PLEKHM1 PTK2 TTC12 XKR6
Frequency of unenthusiasm / disinterest in last 2 weeks	6.8	4	0	0.0	1.00	7.8e-05	ANKK1 DRD2 EXD2 TTC12
Relative age voice broke	2.3	1	1	2.2	0.00	1.0e+00	PLEKHM1
Taking other prescription medications	3.2	1	0	0.0	0.00	1.0e+00	GATAD2A
Age when periods started (menarche)	1.8	1	0	0.0	0.00	1.0e+00	PLEKHM1
Heel bone mineral density (BMD) T-score, automated (left)	4.3	2	2	4.4	0.00	1.0e+00	FAM86B3P XKR6
High blood pressure	4.4	4	3	6.7	-0.65	3.5e-01	FAM86B3P FURIN TOP3A XKR6
Medication: Atenolol	1.5	1	0	0.0	0.00	1.0e+00	FURIN
Medication: Levothyroxine sodium	2.5	2	0	0.0	0.00	1.0e+00	FAM86B3P XKR6
Sitting height	2.4	2	2	4.4	0.00	1.0e+00	PLEKHM1 PTCH1
High blood pressure (mother)	2.4	1	1	2.2	0.00	1.0e+00	FURIN
Body mass index (BMI)	2.5	2	2	4.4	0.00	1.0e+00	FAM86B3P XKR6
Impedance of leg (left)	3.4	6	4	8.9	0.49	3.3e-01	FAM86B3P FURIN GATAD2A MMAB PLEKHM1 XKR6
Leg predicted mass (left)	2.0	6	3	6.7	-0.08	8.8e-01	FAM86B3P FURIN GATAD2A MMAB PTCH1 XKR6
Trunk fat mass	2.1	5	1	2.2	0.39	4.4e-01	ANKK1 EXD2 PLEKHM1 TTC12 XKR6
Waist circumference	2.2	2	2	4.4	0.00	1.0e+00	ANKK1 TTC12
Number of incorrect matches in round	2.3	1	1	2.2	0.00	1.0e+00	FURIN
Nervous feelings	9.3	6	3	6.7	0.96	2.5e-03	ANKK1 FAM86B3P ORC4 PLEKHM1 TTC12 XKR6
Frequency of tenseness / restlessness in last 2 weeks	8.3	7	2	4.4	0.99	1.1e-05	ANKK1 DRD2 MMAB PLEKHM1 RP11-165J3.6 TOP3A TTC12
Hearing difficulty/problems with background noise	4.9	4	0	0.0	0.99	1.4e-02	ANKK1 MMAB PLEKHM1 TTC12
Hair/balding pattern: Pattern 2	2.3	1	1	2.2	0.00	1.0e+00	PLEKHM1
Forced vital capacity (FVC)	3.7	2	2	4.4	0.00	1.0e+00	PLEKHM1 PTCH1
Heel bone mineral density (BMD) T-score, automated (right)	4.4	2	2	4.4	0.00	1.0e+00	FAM86B3P XKR6
Ever unenthusiastic/disinterested for a whole week	2.4	1	0	0.0	0.00	1.0e+00	PLEKHM1
Financial difficulties in last 2 years	4.0	1	0	0.0	0.00	1.0e+00	DRD2
Mouth/teeth dental problems	3.3	1	0	0.0	0.00	1.0e+00	PLEKHM1
Heart attack	2.3	1	0	0.0	0.00	1.0e+00	FURIN
Allergy	2.2	1	0	0.0	0.00	1.0e+00	FURIN
Fluid intelligence score	1.4	1	0	0.0	0.00	1.0e+00	PLEKHM1
Neuroticism score	18.4	15	10	22.2	0.97	3.7e-10	ANKK1 C1orf123 DRD2 EXD2 FAM86B3P GRM8 MMAB ORC4 PLEKHM1 PTCH1 PTK2 RP11-165J3.6 TOP3A TTC12 XKR6
Weight	1.9	4	1	2.2	-0.01	9.8e-01	ANKK1 FAM86B3P TTC12 XKR6
Impedance of arm (right)	2.4	3	3	6.7	0.00	1.0e+00	FAM86B3P PLEKHM1 XKR6
Arm fat percentage (right)	2.3	5	0	0.0	0.24	6.4e-01	ANKK1 EXD2 FAM86B3P TTC12 XKR6
Trunk fat-free mass	1.5	3	1	2.2	0.00	1.0e+00	GATAD2A PTCH1 XKR6
Hip circumference	1.8	5	1	2.2	0.14	7.9e-01	ANKK1 FAM86B3P PTCH1 TTC12 XKR6
Father's age at death	2.5	1	0	0.0	0.00	1.0e+00	XKR6
Worrier / anxious feelings	10.6	7	3	6.7	0.92	3.1e-03	FAM86B3P MMAB ORC4 PLEKHM1 PTCH1 RP11-165J3.6 XKR6
Frequency of tiredness / lethargy in last 2 weeks	7.8	6	3	6.7	0.99	5.0e-05	ANKK1 EXD2 MMAB PTK2 RP11-165J3.6 TTC12
Hair/balding pattern: Pattern 3	4.1	1	1	2.2	0.00	1.0e+00	PLEKHM1
Number of live births	2.4	2	0	0.0	0.00	1.0e+00	PLEKHM1 TOP3A
Forced expiratory volume in 1-second (FEV1)	3.4	3	2	4.4	0.00	1.0e+00	FAM86B3P PLEKHM1 PTCH1
Qualifications: A levels/AS levels or equivalent	1.6	1	0	0.0	0.00	1.0e+00	PLEKHM1
Medication: Ibuprofen (e.g. Nurofen)	1.9	1	0	0.0	0.00	1.0e+00	PLEKHM1
Medication: Cholesterol lowering	2.7	2	0	0.0	0.00	1.0e+00	EXD2 GATAD2A
Forced expiratory volume in 1-second (FEV1), Best measure	3.0	2	1	2.2	0.00	1.0e+00	PLEKHM1 PTCH1
Impedance of arm (left)	2.3	3	3	6.7	0.00	1.0e+00	FAM86B3P PLEKHM1 XKR6
Arm fat mass (right)	2.5	4	2	4.4	0.00	9.9e-01	ANKK1 FAM86B3P TTC12 XKR6
Trunk predicted mass	1.5	3	1	2.2	0.00	1.0e+00	GATAD2A PTCH1 XKR6
Standing height	1.2	5	2	4.4	0.56	3.2e-01	FAM86B3P PLEKHM1 PTCH1 RP11-165J3.6 TOP3A
Tense / 'highly strung'	9.6	9	3	6.7	0.99	7.4e-08	ANKK1 C1orf123 DRD2 FAM86B3P ORC4 PTCH1 RP11-165J3.6 TTC12 XKR6
Seen doctor (GP) for nerves, anxiety, tension or depression	6.3	3	1	2.2	0.00	1.0e+00	ANKK1 DRD2 TTC12
Hair/balding pattern: Pattern 4	5.3	1	1	2.2	0.00	1.0e+00	PLEKHM1
Birth weight of first child	2.6	1	1	2.2	0.00	1.0e+00	FURIN
Peak expiratory flow (PEF)	3.3	3	1	2.2	0.00	1.0e+00	FAM86B3P PLEKHM1 XKR6
Medication: Paracetamol	3.5	1	1	2.2	0.00	1.0e+00	PLEKHM1
Headache pain in last month	4.3	1	1	2.2	0.00	1.0e+00	PLEKHM1
Medication for cholesterol, blood pressure or diabetes	2.5	1	0	0.0	0.00	1.0e+00	FURIN
Hypothyroidism/myxoedema (self-reported)	3.2	2	2	4.4	0.00	1.0e+00	FAM86B3P XKR6
Birth weight	2.6	2	2	4.4	0.00	1.0e+00	FURIN PTCH1
Forced vital capacity (FVC), Best measure	3.5	3	2	4.4	0.00	1.0e+00	EXD2 PLEKHM1 PTCH1
Body fat percentage	2.3	3	1	2.2	1.00	1.1e-03	ANKK1 EXD2 TTC12
Leg fat percentage (right)	2.5	5	1	2.2	0.33	5.3e-01	ANKK1 EXD2 FAM86B3P TTC12 XKR6
Arm fat-free mass (right)	1.5	3	1	2.2	0.00	1.0e+00	FAM86B3P PTCH1 XKR6
Comparative body size at age 10	3.1	4	3	6.7	-0.99	5.1e-03	FAM86B3P GATAD2A RP11-165J3.6 XKR6
Worry too long after embarrassment	10.6	6	5	11.1	0.96	4.9e-04	ANKK1 DRD2 FAM86B3P PLEKHM1 TTC12 XKR6
Seen a psychiatrist for nerves, anxiety, tension or depression	4.0	1	1	2.2	0.00	1.0e+00	C1orf123
Wheeze or whistling in the chest in last year	3.0	2	0	0.0	0.00	1.0e+00	ANKK1 RP11-165J3.6
Age at first live birth	3.1	2	0	0.0	0.00	1.0e+00	GATAD2A PLEKHM1
Health satisfaction	4.2	1	0	0.0	0.00	1.0e+00	DRD2
Qualifications: College or University degree	2.2	2	1	2.2	0.00	1.0e+00	EXD2 PLEKHM1
Medication for pain relief, constipation, heartburn	2.4	2	1	2.2	0.00	1.0e+00	PLEKHM1 RP11-165J3.6
Neck or shoulder pain in last month	2.6	2	0	0.0	0.00	1.0e+00	EXD2 PTK2
Medication: Blood pressure	3.0	3	0	0.0	0.00	1.0e+00	FURIN TOP3A XKR6
Angina (self-reported)	1.8	1	0	0.0	0.00	1.0e+00	FURIN
Whole body fat mass	2.3	5	1	2.2	0.29	5.7e-01	ANKK1 EXD2 FAM86B3P TTC12 XKR6
Leg fat mass (right)	2.6	5	3	6.7	0.21	7.0e-01	ANKK1 EXD2 FAM86B3P TTC12 XKR6
Arm predicted mass (right)	1.5	3	1	2.2	0.00	1.0e+00	FAM86B3P PTCH1 XKR6
Alcohol intake frequency.	3.2	3	1	2.2	0.00	1.0e+00	DRD2 PLEKHM1 TOP3A
Comparative height size at age 10	1.5	3	1	2.2	0.37	6.3e-01	ANKK1 PLEKHM1 PTCH1
Suffer from 'nerves'	7.6	6	2	4.4	0.99	3.3e-04	ANKK1 DRD2 FAM86B3P PTCH1 TTC12 XKR6
Overall health rating	5.6	5	2	4.4	0.65	1.6e-01	ANKK1 PTK2 RP11-165J3.6 TTC12 XKR6
Hypertension (Self-reported)	4.3	4	3	6.7	-0.66	3.4e-01	FAM86B3P FURIN TOP3A XKR6
Forced expiratory volume in 1-second (FEV1), predicted	2.1	2	0	0.0	0.00	1.0e+00	PTCH1 TOP3A
Whole body fat-free mass	1.7	5	2	4.4	-0.15	8.1e-01	FAM86B3P GATAD2A MMAB PTCH1 XKR6
Leg fat-free mass (right)	2.0	6	4	8.9	-0.07	9.0e-01	FAM86B3P FURIN GATAD2A MMAB PTCH1 XKR6
Arm fat percentage (left)	2.1	5	1	2.2	0.16	7.6e-01	ANKK1 EXD2 FAM86B3P TTC12 XKR6
Handedness (chirality/laterality): Left-handed	2.7	2	1	2.2	0.00	1.0e+00	FURIN PLEKHM1
Mood swings	10.8	8	6	13.3	0.99	6.8e-07	ANKK1 DRD2 FAM86B3P PLEKHM1 PTK2 RP11-165J3.6 TTC12 XKR6
Loneliness, isolation	5.2	2	0	0.0	0.00	1.0e+00	ORC4 PLEKHM1
Long-standing illness, disability or infirmity	3.4	2	0	0.0	0.00	1.0e+00	ANKK1 TTC12
Mouth/teeth dental problems: Mouth ulcers	2.5	1	1	2.2	0.00	1.0e+00	PLEKHM1
Medication for cholesterol	2.8	1	0	0.0	0.00	1.0e+00	PLEKHM1
Back pain experienced in last month	2.1	1	0	0.0	0.00	1.0e+00	PTK2
Medication: Aspirin	2.1	1	0	0.0	0.00	1.0e+00	FURIN
Smoking status: Current	3.3	2	0	0.0	0.00	1.0e+00	EXD2 XKR6
Forced expiratory volume in 1-second (FEV1), predicted percentage	2.6	1	1	2.2	0.00	1.0e+00	PLEKHM1
Whole body water mass	1.7	5	2	4.4	-0.16	8.0e-01	FAM86B3P GATAD2A MMAB PTCH1 XKR6
Leg predicted mass (right)	2.0	6	4	8.9	-0.07	9.0e-01	FAM86B3P FURIN GATAD2A MMAB PTCH1 XKR6
Arm fat mass (left)	2.3	4	2	4.4	-0.02	9.7e-01	ANKK1 FAM86B3P TTC12 XKR6
Number of self-reported non-cancer illnesses	3.0	2	0	0.0	0.00	1.0e+00	TOP3A TTC12
Average weekly champagne plus white wine intake	2.3	1	0	0.0	0.00	1.0e+00	C1orf123
Miserableness	10.5	9	6	13.3	0.98	2.3e-07	ANKK1 DRD2 FAM86B3P MMAB ORC4 PLEKHM1 RP11-165J3.6 TTC12 XKR6
Guilty feelings	9.4	7	4	8.9	0.98	2.0e-05	ANKK1 DRD2 FAM86B3P PLEKHM1 PTCH1 TTC12 XKR6
Medication: Blood pressure	4.2	4	3	6.7	-0.94	6.0e-02	FAM86B3P FURIN PLEKHM1 XKR6
High cholesterol (Self-reported)	2.1	1	1	2.2	0.00	1.0e+00	GATAD2A
Medication: Bendroflumethiazide	3.9	2	1	2.2	0.00	1.0e+00	FAM86B3P XKR6
Medication: Paracetamol	2.8	1	1	2.2	0.00	1.0e+00	PLEKHM1
Basal metabolic rate	1.7	5	2	4.4	-0.18	7.7e-01	FAM86B3P GATAD2A MMAB PTCH1 XKR6
Leg fat percentage (left)	2.6	5	1	2.2	0.31	5.4e-01	ANKK1 EXD2 FAM86B3P TTC12 XKR6
Arm fat-free mass (left)	1.6	3	1	2.2	0.00	1.0e+00	FAM86B3P PTCH1 XKR6
Number of operations (self-reported)	3.3	1	0	0.0	0.00	1.0e+00	FURIN
Average weekly beer plus cider intake	1.9	1	0	0.0	0.00	1.0e+00	XKR6
Irritability	9.5	7	3	6.7	0.96	5.3e-04	ANKK1 DRD2 FAM86B3P MMAB ORC4 PLEKHM1 XKR6
Fractured/broken bones in last 5 years	1.3	1	0	0.0	0.00	1.0e+00	PLEKHM1
Diastolic blood pressure, automated reading	2.8	3	3	6.7	0.00	1.0e+00	FAM86B3P FURIN XKR6
Ever depressed for a whole week	2.6	1	0	0.0	0.00	1.0e+00	PLEKHM1
Myopia	2.2	1	0	0.0	0.00	1.0e+00	GATAD2A
Vascular/heart problems diagnosed by doctor	4.3	4	2	4.4	0.64	3.6e-01	FAM86B3P FURIN TOP3A XKR6
Pain experienced in last month	3.1	3	0	0.0	0.00	1.0e+00	MMAB PLEKHM1 PTK2
Impedance of whole body	2.9	4	4	8.9	0.44	5.6e-01	FAM86B3P GATAD2A PLEKHM1 XKR6
Leg fat mass (left)	2.5	5	3	6.7	0.20	7.0e-01	ANKK1 EXD2 FAM86B3P TTC12 XKR6
Arm predicted mass (left)	1.6	3	2	4.4	0.00	1.0e+00	FAM86B3P PTCH1 XKR6

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Adipose Subcutaneous	9	0.258	1.7
GTEx	Adipose Visceral Omentum	11	0.540	1.8
GTEx	Adrenal Gland	9	0.618	1.8
GTEx	Artery Aorta	14	0.470	1.9
GTEx	Artery Coronary	10	0.845	2.2
GTEx	Artery Tibial	7	0.186	1.7
GTEx	Brain Caudate basal ganglia	4	0.435	1.9
GTEx	Brain Cerebellar Hemisphere	9	0.604	2.0
GTEx	Brain Cerebellum	7	0.353	1.9
GTEx	Brain Cortex	7	0.676	2.1
GTEx	Brain Frontal Cortex BA9	6	0.649	2.1
GTEx	Brain Hippocampus	4	0.763	2.1
GTEx	Brain Hypothalamus	4	0.678	2.1
GTEx	Brain Nucleus accumbens basal ganglia	7	0.809	2.1
GTEx	Brain Putamen basal ganglia	5	0.801	2.1
GTEx	Breast Mammary Tissue	11	0.557	1.8
GTEx	Breast Mammary Tissue (Male)	7	0.587	2.0
GTEx	Breast Mammary Tissue (Female)	13	0.791	1.9
GTEx	Cells EBV-transformed lymphocytes	12	0.843	2.0
GTEx	Cells Transformed fibroblasts	11	0.262	1.7
GTEx	Colon Sigmoid	10	0.684	1.9
GTEx	Colon Transverse	12	0.581	1.9
GTEx	Esophagus Gastroesophageal Junction	9	0.623	2.0
GTEx	Esophagus Mucosa	15	0.452	1.8
GTEx	Esophagus Muscularis	14	0.433	1.9
GTEx	Heart Atrial Appendage	9	0.570	1.9
GTEx	Heart Left Ventricle	10	0.654	2.0
GTEx	Liver	5	0.697	2.0
GTEx	Lung	13	0.452	1.8
GTEx	Muscle Skeletal	11	0.381	1.8
GTEx	Nerve Tibial	10	0.231	1.7
GTEx	Ovary	8	0.881	2.1
GTEx	Pancreas	10	0.613	2.0
GTEx	Pituitary	7	0.628	1.9
GTEx	Prostate	6	0.719	1.9
GTEx	Skin Not Sun Exposed Suprapubic	12	0.488	1.8
GTEx	Skin Sun Exposed Lower leg	12	0.330	1.8
GTEx	Small Intestine Terminal Ileum	6	1.302	2.3
GTEx	Spleen	10	0.709	1.9
GTEx	Stomach	7	0.481	2.0
GTEx	Testis	11	0.349	1.8
GTEx	Thyroid	14	0.350	1.8
GTEx	Uterus	8	1.411	2.4
GTEx	Vagina	6	0.945	2.1
GTEx	Whole Blood	8	0.401	1.7
METSIM	Adipose	1	0.022	1.5
NTR	Blood	4	0.167	1.7
ROSMAP	Brain Pre-frontal Cortex	8	0.182	1.6
YFS	Blood	2	0.043	1.5
CommonMind	Brain Pre-frontal Cortex	7	0.130	1.6
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	4	0.242	1.7
The Cancer Genome Atlas	Breast Invasive Carcinoma	5	0.113	1.5
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	3	0.273	1.6
The Cancer Genome Atlas	Colon Adenocarcinoma	2	0.097	1.5
The Cancer Genome Atlas	Esophageal Carcinoma	3	0.438	1.7
The Cancer Genome Atlas	Glioblastoma Multiforme	4	0.391	1.7
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	5	0.184	1.6
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	7	0.171	1.6
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	5	0.244	1.6
The Cancer Genome Atlas	Brain Lower Grade Glioma	5	0.116	1.6
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	4	0.362	1.6
The Cancer Genome Atlas	Lung Adenocarcinoma	8	0.272	1.6
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	6	0.239	1.6
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	4	0.251	1.6
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	4	0.241	1.6
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	4	0.301	1.5
The Cancer Genome Atlas	Prostate Adenocarcinoma	9	0.195	1.6
The Cancer Genome Atlas	Rectum Adenocarcinoma	2	0.289	1.5
The Cancer Genome Atlas	Soft Tissue Sarcoma	3	0.281	1.7
The Cancer Genome Atlas	Skin Cutaneous Melanoma	1	0.187	1.4
The Cancer Genome Atlas	Stomach Adenocarcinoma	3	0.178	1.6
The Cancer Genome Atlas	Testicular Germ Cell Tumors	5	0.391	1.6
The Cancer Genome Atlas	Thyroid Carcinoma	9	0.174	1.6
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	2	0.394	1.6