539 significantly associated models · 55 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 52981087 | 54492569 | 3 | 1 | 1.9e-09 | 1.1e-08 | 5.7e-01 | 99 | C1orf123 |
2 | 2 | 147993969 | 149475737 | 1 | 1 | 3.1e-07 | 3.9e-08 | 9.4e-03 | 78 | ORC4 |
3 | 7 | 125383444 | 127590914 | 1 | 1 | 4.9e-11 | 4.3e-14 | 1.9e-06 | 60 | GRM8 |
4 | 8 | 8092025 | 9669775 | 6 | 1 | 1.4e-09 | 6.6e-09 | 1.3e-02 | 82 | FAM86B3P |
5 | 8 | 10056664 | 11860845 | 7 | 1 | 7.6e-12 | 7.5e-11 | 1.1e-01 | 94 | XKR6 |
6 | 8 | 141421996 | 142253369 | 1 | 1 | 1.5e-07 | 4.4e-07 | 7.8e-01 | 100 | PTK2 |
7 | 9 | 33056378 | 34496024 | 1 | 1 | 7.2e-08 | 1.1e-07 | 4.2e-03 | 71 | PRSS3 |
8 | 9 | 95502571 | 96898436 | 1 | 1 | 9.2e-09 | 1.7e-08 | 4.9e-01 | 98 | RP11-165J3.6 |
9 | 9 | 97520168 | 98975128 | 1 | 1 | 6.1e-12 | 1.6e-11 | 2.3e-01 | 97 | PTCH1 |
10 | 11 | 112950782 | 113591832 | 3 | 4 | 7.4e-10 | 8.9e-09 | NaN | NaN | ANKK1 DRD2 TTC12 |
11 | 12 | 109231851 | 110729807 | 4 | 1 | 1.2e-07 | 7.0e-08 | 1.0e+00 | 100 | MMAB |
12 | 14 | 69412804 | 69954376 | 1 | 1 | 2.1e-07 | 3.0e-07 | 5.4e-02 | 86 | EXD2 |
13 | 15 | 90718541 | 92120170 | 2 | 1 | 3.8e-08 | 3.2e-08 | 1.0e+00 | 100 | FURIN |
14 | 17 | 17484654 | 18914778 | 1 | 1 | 8.3e-08 | 4.1e-06 | 4.5e-03 | 62 | TOP3A |
15 | 17 | 42413481 | 45796313 | 21 | 1 | 5.4e-23 | 1.6e-21 | 4.3e-01 | 99 | PLEKHM1 |
16 | 19 | 18829733 | 20313262 | 1 | 1 | 8.3e-08 | 9.7e-07 | 9.0e-01 | 100 | GATAD2A |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Uterus | 8 | 1.411 | 2.4 |
GTEx | Small Intestine Terminal Ileum | 6 | 1.302 | 2.3 |
GTEx | Artery Coronary | 10 | 0.845 | 2.2 |
GTEx | Brain Cortex | 7 | 0.676 | 2.1 |
GTEx | Brain Frontal Cortex BA9 | 6 | 0.649 | 2.1 |
GTEx | Brain Hippocampus | 4 | 0.763 | 2.1 |
GTEx | Brain Hypothalamus | 4 | 0.678 | 2.1 |
GTEx | Brain Nucleus accumbens basal ganglia | 7 | 0.809 | 2.1 |
GTEx | Brain Putamen basal ganglia | 5 | 0.801 | 2.1 |
GTEx | Ovary | 8 | 0.881 | 2.1 |
GTEx | Vagina | 6 | 0.945 | 2.1 |
GTEx | Brain Cerebellar Hemisphere | 9 | 0.604 | 2.0 |
GTEx | Breast Mammary Tissue (Male) | 7 | 0.587 | 2.0 |
GTEx | Cells EBV-transformed lymphocytes | 12 | 0.843 | 2.0 |
GTEx | Esophagus Gastroesophageal Junction | 9 | 0.623 | 2.0 |
GTEx | Heart Left Ventricle | 10 | 0.654 | 2.0 |
GTEx | Liver | 5 | 0.697 | 2.0 |
GTEx | Pancreas | 10 | 0.613 | 2.0 |
GTEx | Stomach | 7 | 0.481 | 2.0 |
GTEx | Artery Aorta | 14 | 0.470 | 1.9 |
GTEx | Brain Caudate basal ganglia | 4 | 0.435 | 1.9 |
GTEx | Brain Cerebellum | 7 | 0.353 | 1.9 |
GTEx | Breast Mammary Tissue (Female) | 13 | 0.791 | 1.9 |
GTEx | Colon Sigmoid | 10 | 0.684 | 1.9 |
GTEx | Colon Transverse | 12 | 0.581 | 1.9 |
GTEx | Esophagus Muscularis | 14 | 0.433 | 1.9 |
GTEx | Heart Atrial Appendage | 9 | 0.570 | 1.9 |
GTEx | Pituitary | 7 | 0.628 | 1.9 |
GTEx | Prostate | 6 | 0.719 | 1.9 |
GTEx | Spleen | 10 | 0.709 | 1.9 |
GTEx | Adipose Visceral Omentum | 11 | 0.540 | 1.8 |
GTEx | Adrenal Gland | 9 | 0.618 | 1.8 |
GTEx | Breast Mammary Tissue | 11 | 0.557 | 1.8 |
GTEx | Esophagus Mucosa | 15 | 0.452 | 1.8 |
GTEx | Lung | 13 | 0.452 | 1.8 |
GTEx | Muscle Skeletal | 11 | 0.381 | 1.8 |
GTEx | Skin Not Sun Exposed Suprapubic | 12 | 0.488 | 1.8 |
GTEx | Skin Sun Exposed Lower leg | 12 | 0.330 | 1.8 |
GTEx | Testis | 11 | 0.349 | 1.8 |
GTEx | Thyroid | 14 | 0.350 | 1.8 |
GTEx | Adipose Subcutaneous | 9 | 0.258 | 1.7 |
GTEx | Artery Tibial | 7 | 0.186 | 1.7 |
GTEx | Cells Transformed fibroblasts | 11 | 0.262 | 1.7 |
GTEx | Nerve Tibial | 10 | 0.231 | 1.7 |
GTEx | Whole Blood | 8 | 0.401 | 1.7 |
NTR | Blood | 4 | 0.167 | 1.7 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 4 | 0.242 | 1.7 |
The Cancer Genome Atlas | Esophageal Carcinoma | 3 | 0.438 | 1.7 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 4 | 0.391 | 1.7 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 3 | 0.281 | 1.7 |
ROSMAP | Brain Pre-frontal Cortex | 8 | 0.182 | 1.6 |
CommonMind | Brain Pre-frontal Cortex | 7 | 0.130 | 1.6 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 3 | 0.273 | 1.6 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 5 | 0.184 | 1.6 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 7 | 0.171 | 1.6 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 5 | 0.244 | 1.6 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 5 | 0.116 | 1.6 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 4 | 0.362 | 1.6 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 8 | 0.272 | 1.6 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 6 | 0.239 | 1.6 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 4 | 0.251 | 1.6 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 4 | 0.241 | 1.6 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 9 | 0.195 | 1.6 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 3 | 0.178 | 1.6 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 5 | 0.391 | 1.6 |
The Cancer Genome Atlas | Thyroid Carcinoma | 9 | 0.174 | 1.6 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 2 | 0.394 | 1.6 |
METSIM | Adipose | 1 | 0.022 | 1.5 |
YFS | Blood | 2 | 0.043 | 1.5 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 5 | 0.113 | 1.5 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 2 | 0.097 | 1.5 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 4 | 0.301 | 1.5 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 2 | 0.289 | 1.5 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 1 | 0.187 | 1.4 |