TWAS
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Traits
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Traits
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Nervous feelings
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chr20:32,594,714-34,225,302
Best TWAS P=6.46e-08 · Best GWAS P=1.51e-08 conditioned to 0.132
32.6M
32.8M
33M
33.2M
33.4M
33.6M
33.8M
34M
34.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Heart Left Ventricle
GSS
0.12
0.06
enet
10
0.04
2.2e-03
4.3
5.4
6.5e-08
0.53
0.48
0.35
TRUE
4
GTEx
Thyroid
TP53INP2
0.09
0.05
lasso
7
0.04
3.7e-04
4.9
-5.4
8.3e-08
-0.82
0.08
0.91
TRUE
1
GTEx
Breast Mammary Tissue (Female)
NCOA6
0.08
-0.01
lasso
4
0.00
4.6e-01
4.0
5.3
9.2e-08
0.52
0.05
0.31
FALSE
3
GTEx
Skin Not Sun Exposed Suprapubic
NCOA6
0.13
0.03
enet
12
0.03
1.5e-02
5.0
5.2
1.9e-07
0.62
0.09
0.72
FALSE
5
YFS
Blood
TP53INP2
0.02
0.02
lasso
15
0.01
1.3e-05
4.9
-5.2
2.0e-07
-0.83
0.10
0.90
FALSE