Best TWAS P=6.46e-08 · Best GWAS P=1.51e-08 conditioned to 0.132
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | NCOA6 | 0.08 | -0.01 | lasso | 4 | 0.00 | 4.6e-01 | 4.0 | 5.3 | 9.2e-08 | 0.52 | 0.05 | 0.31 | FALSE |
| 2 | GTEx | Heart Left Ventricle | GSS | 0.12 | 0.06 | enet | 10 | 0.04 | 2.2e-03 | 4.3 | 5.4 | 6.5e-08 | 0.53 | 0.48 | 0.35 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | NCOA6 | 0.13 | 0.03 | enet | 12 | 0.03 | 1.5e-02 | 5.0 | 5.2 | 1.9e-07 | 0.62 | 0.09 | 0.72 | FALSE |
| 4 | GTEx | Thyroid | TP53INP2 | 0.09 | 0.05 | lasso | 7 | 0.04 | 3.7e-04 | 4.9 | -5.4 | 8.3e-08 | -0.82 | 0.08 | 0.91 | TRUE |
| 5 | YFS | Blood | TP53INP2 | 0.02 | 0.02 | lasso | 15 | 0.01 | 1.3e-05 | 4.9 | -5.2 | 2.0e-07 | -0.83 | 0.10 | 0.90 | FALSE |