[Hub]/) : Traits : Hypertension (Self-reported) : ← →

chr7:6,502,367-7,988,091

Best TWAS P=2.05e-14 · Best GWAS P=1e-10 conditioned to 0.101

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	C1GALT1	0.26	0.15	enet	20	0.23	1.1e-27	3.9	6.4	1.3e-10	0.68	0.86	0.14	FALSE
2	GTEx	Brain Caudate basal ganglia	C1GALT1	0.27	0.18	enet	8	0.20	2.4e-06	6.5	6.3	3.0e-10	0.93	0.00	0.99	FALSE
3	GTEx	Brain Cerebellar Hemisphere	C1GALT1	0.33	0.24	lasso	4	0.20	6.1e-06	6.0	5.8	6.9e-09	0.66	0.03	0.94	FALSE
4	GTEx	Brain Cortex	C1GALT1	0.32	0.10	lasso	13	0.13	1.9e-04	6.5	6.0	1.8e-09	0.90	0.01	0.97	FALSE
5	GTEx	Brain Nucleus accumbens basal ganglia	C1GALT1	0.28	0.00	enet	28	0.01	1.8e-01	6.5	6.3	2.4e-10	0.86	0.01	0.92	FALSE
6	GTEx	Breast Mammary Tissue	C1GALT1	0.23	0.15	lasso	8	0.15	5.1e-08	6.1	6.0	1.7e-09	0.97	0.00	1.00	FALSE
7	GTEx	Breast Mammary Tissue (Male)	C1GALT1	0.00	0.03	lasso	1	0.09	4.0e-03	6.1	6.1	8.4e-10	0.99	0.03	0.41	FALSE
8	GTEx	Cells Transformed fibroblasts	C1GALT1	0.12	0.03	lasso	3	0.05	1.0e-04	4.1	5.6	1.8e-08	0.73	0.02	0.96	FALSE
9	GTEx	Colon Sigmoid	C1GALT1	0.52	0.25	enet	38	0.31	1.0e-11	6.5	5.9	4.6e-09	0.84	0.00	1.00	FALSE
10	GTEx	Colon Transverse	C1GALT1	0.32	0.23	lasso	4	0.30	8.0e-15	6.1	6.4	1.3e-10	0.78	0.02	0.98	FALSE
11	GTEx	Esophagus Mucosa	C1GALT1	0.33	0.19	lasso	6	0.18	2.8e-12	6.2	6.6	3.1e-11	0.85	0.01	0.99	FALSE
12	GTEx	Esophagus Muscularis	C1GALT1	0.36	0.16	lasso	8	0.27	1.9e-16	5.3	6.5	7.4e-11	0.74	0.06	0.94	FALSE
13	GTEx	Heart Left Ventricle	C1GALT1	0.17	0.04	enet	23	0.05	1.5e-03	6.2	7.6	2.1e-14	0.69	0.02	0.95	TRUE
14	GTEx	Lung	C1GALT1	0.18	0.13	lasso	3	0.15	1.1e-11	5.3	6.9	6.7e-12	0.80	0.01	0.99	FALSE
15	GTEx	Nerve Tibial	C1GALT1	0.44	0.28	lasso	12	0.40	2.0e-30	4.1	6.3	3.2e-10	0.76	0.21	0.79	FALSE
16	GTEx	Ovary	C1GALT1	0.22	0.14	enet	11	0.15	1.8e-04	6.0	5.9	4.4e-09	0.81	0.03	0.88	FALSE
17	GTEx	Pancreas	C1GALT1	0.44	0.11	enet	24	0.22	8.8e-10	4.1	6.3	3.4e-10	0.76	0.05	0.95	FALSE
18	GTEx	Skin Sun Exposed Lower leg	C1GALT1	0.22	0.04	lasso	9	0.10	4.8e-09	6.0	6.7	2.1e-11	0.78	0.02	0.98	FALSE
19	GTEx	Stomach	C1GALT1	0.24	0.07	enet	17	0.12	1.9e-06	6.0	6.3	4.0e-10	0.75	0.03	0.97	FALSE
20	GTEx	Thyroid	C1GALT1	0.30	0.27	lasso	3	0.31	3.9e-24	4.1	5.5	3.3e-08	0.68	0.99	0.01	FALSE
21	GTEx	Uterus	C1GALT1	0.38	0.28	enet	8	0.32	2.0e-07	6.1	6.4	1.6e-10	0.85	0.02	0.94	FALSE
22	METSIM	Adipose	C1GALT1	0.22	0.16	lasso	9	0.23	5.1e-34	6.5	6.6	3.2e-11	0.85	0.00	1.00	FALSE
23	YFS	Blood	C1GALT1	0.35	0.20	enet	45	0.32	4.3e-109	5.3	5.3	1.1e-07	0.64	0.62	0.38	FALSE
24	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	C1GALT1	0.16	0.12	lasso	7	0.14	3.7e-08	6.3	6.8	1.3e-11	0.84	0.01	0.99	FALSE
25	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	C1GALT1	0.27	0.06	enet	22	0.10	8.1e-05	6.0	6.2	5.2e-10	0.58	0.04	0.86	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	C1GALT1	0.12	0.05	enet	10	0.13	9.9e-14	3.9	5.1	2.8e-07	0.65	0.40	0.60	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	C1GALT1	0.05	0.01	lasso	2	0.01	3.8e-02	6.1	6.4	1.9e-10	0.96	0.00	0.94	FALSE