Hub : Traits :

Hypertension (Self-reported)

1359 significantly associated models · 374 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	1	5829039	7221458	1	1	1.9e-07	1.2e-06	1.5e-02	75	TNFRSF25
2	1	7715776	9571422	2	1	7.9e-09	1.9e-08	2.3e-01	96	RP5-1115A15.1
3	1	10435170	12600396	8	9	1.7e-28	3.7e-30	NaN	NaN	CLCN6 MTHFR NPPA NPPA-AS1 RP4-635E18.7
4	1	26428864	28406173	4	2	1.5e-08	2.9e-07	2.6e-01	95	FCN3 PIGV
5	1	88621347	90053563	1	1	1.0e-09	8.8e-10	9.0e-02	92	GTF2B
6	1	112312154	113941737	5	2	5.4e-17	8.5e-22	1.7e-10	56	CAPZA1 RHOC
7	1	230142626	231548480	1	1	3.4e-14	2.4e-12	4.9e-02	92	AGT
8	2	24021231	26068509	4	2	6.6e-12	2.7e-10	2.0e-02	86	EFR3B NCOA1
9	2	26223547	27689899	2	2	5.4e-09	1.4e-34	3.0e-25	28	KCNK3 SLC35F6
10	2	36778887	38298877	2	1	3.6e-10	1.4e-09	1.0e+00	100	PRKD3
11	2	182763586	183632923	1	1	2.3e-07	3.3e-09	1.3e-03	70	PDE1A
12	2	218622292	220128895	1	1	6.1e-08	6.4e-05	6.6e-01	99	USP37
13	3	10617048	12457119	2	1	9.5e-09	9.2e-11	2.6e-03	78	ATG7
14	3	19959756	20466630	1	1	2.0e-07	7.9e-08	1.9e-03	66	SGOL1
15	3	26563909	28211713	2	1	2.2e-16	9.7e-18	9.2e-03	91	SLC4A7
16	3	38812165	40267321	1	1	2.4e-07	7.2e-06	2.2e-03	54	MOBP
17	3	47204518	49538932	9	2	4.5e-12	2.9e-12	1.0e+00	100	CCDC36 FCF1P2
18	3	137189600	138819532	2	1	7.7e-08	4.1e-08	2.2e-01	95	MRAS
19	3	157125828	159106064	3	1	2.9e-09	7.5e-08	3.1e-01	96	RP11-538P18.2
20	3	183204923	184607480	1	1	1.8e-07	6.5e-07	4.2e-01	97	ABCF3
21	4	17104059	18507692	1	1	4.5e-09	1.8e-08	4.1e-03	74	DCAF16
22	4	25880334	27452482	1	2	2.9e-09	2.8e-12	2.4e-07	46	TBC1D19
23	4	37915462	39361551	1	1	1.8e-07	1.9e-08	6.4e-07	22	RP11-617D20.1
24	4	80407869	82578407	3	2	4.8e-20	1.1e-67	2.4e-44	35	C4orf22 PRDM8
25	4	102868793	104627833	5	1	2.3e-11	1.7e-10	8.8e-01	100	CISD2
26	4	110590479	112179424	1	1	7.5e-08	7.3e-13	1.1e-08	37	ENPEP
27	4	155960819	157354250	1	1	1.0e-07	3.0e-12	1.4e-11	6	RP11-588K22.2
28	5	60903201	62529686	2	1	1.4e-07	5.9e-07	7.1e-02	87	IPO11
29	5	95750396	96364645	1	1	3.1e-07	1.9e-06	7.4e-02	86	CAST
30	5	130830617	132425049	8	1	2.8e-08	1.2e-07	2.7e-01	96	PDLIM4
31	5	147516165	148894875	1	1	6.1e-08	3.3e-08	6.2e-05	47	ADRB2
32	5	176043333	177591495	2	1	8.4e-08	1.1e-06	1.0e+00	100	DBN1
33	6	14551209	16209635	1	1	9.3e-08	5.2e-07	1.3e-02	76	JARID2
34	6	42586058	44034691	2	1	4.5e-12	1.7e-12	1.0e+00	100	ZNF318
35	6	78880271	80486611	2	1	1.3e-08	1.6e-08	1.8e-01	94	PHIP
36	6	96275538	97699026	3	1	1.7e-08	5.1e-09	8.3e-02	91	UFL1
37	6	117187910	118613435	1	1	1.9e-07	9.1e-10	8.8e-10	0	GOPC
38	6	125970401	127355237	1	1	2.4e-10	1.7e-30	1.8e-23	24	CENPW
39	7	1854263	3264728	1	1	8.2e-11	1.8e-10	1.0e+00	100	LFNG
40	7	6502367	7988091	1	1	2.1e-14	1.0e-10	1.0e-01	94	C1GALT1
41	7	26969253	27533292	2	1	6.3e-15	7.3e-16	6.3e-03	88	HOXA10
42	7	73425238	75714883	6	2	4.3e-09	9.0e-09	3.4e-01	97	PMS2P5 STAG3L1
43	7	76506844	77966572	1	1	9.1e-08	1.3e-06	1.4e-01	91	PTPN12
44	7	99081730	100516003	2	1	4.1e-08	3.6e-07	6.5e-01	99	PVRIG
45	7	129342404	130779678	2	2	4.9e-09	1.1e-12	2.3e-05	64	CEP41 ZC3HC1
46	7	132241297	134834499	4	2	1.1e-08	2.8e-09	4.5e-01	98	AKR1B1 EXOC4
47	8	8092025	13120332	28	2	1.3e-14	4.2e-13	7.1e-04	78	MSRA NEIL2
48	8	29996824	31433801	1	1	2.0e-08	9.4e-09	1.7e-01	94	TEX15
49	8	90238179	91633434	1	1	2.7e-07	3.6e-08	2.8e-02	84	OSGIN2
50	8	95213858	96825195	2	1	1.1e-08	8.9e-08	4.7e-01	98	NDUFAF6
51	8	102002608	103832256	2	1	4.2e-09	1.3e-09	6.2e-04	68	KB-1107E3.1
52	9	35208145	36597142	1	1	8.9e-09	7.0e-09	1.3e-04	56	HRCT1
53	9	135883620	136399075	1	1	3.0e-08	1.5e-07	4.6e-01	98	ABO
54	10	18221643	19601824	2	2	6.2e-12	6.3e-17	4.9e-12	32	CACNB2 NSUN6
55	10	59577377	61286904	1	1	7.3e-10	3.9e-09	6.8e-02	90	BICC1
56	10	63856856	65606229	3	1	1.1e-11	3.6e-10	2.5e-02	87	NRBF2
57	10	87495534	88960852	2	1	7.4e-08	4.9e-08	3.1e-02	84	LDB3
58	10	95379543	96818402	1	1	1.4e-10	2.9e-13	6.6e-05	70	NOC3L
59	10	103572925	105850787	8	1	7.2e-14	4.5e-15	1.8e-02	91	NT5C2
60	10	115244596	116689519	3	3	3.5e-12	6.3e-19	4.6e-08	62	ADRB1 C10orf118 TDRD1
61	10	133652765	135295396	2	2	1.7e-07	7.0e-08	6.0e-01	99	INPP5A STK32C
62	11	1213806	2705175	5	2	6.8e-22	2.0e-23	6.3e-03	92	LSP1 TNNT3
63	11	9003306	10471931	1	1	1.3e-07	5.1e-10	6.8e-08	25	SWAP70
64	11	15741673	17001235	1	1	2.5e-08	9.8e-16	7.5e-10	41	SOX6
65	11	17037793	17619908	1	1	1.3e-07	6.5e-07	2.6e-02	80	NUCB2
66	11	42881882	44596817	2	1	6.1e-08	3.8e-10	6.5e-04	70	HSD17B12
67	11	46010847	48783497	20	1	6.3e-24	1.2e-19	8.2e-07	70	ACP2
68	11	63305184	64701030	1	1	2.0e-08	7.5e-08	1.0e+00	100	VEGFB
69	11	64721908	66333072	3	2	7.6e-10	3.0e-13	2.2e-02	90	CTSW SIPA1
70	11	99859184	101559718	2	1	2.7e-36	2.5e-35	8.5e-02	98	TMEM133
71	11	106485489	108027561	2	1	1.0e-09	7.6e-10	3.3e-02	88	CWF19L2
72	11	110721187	112491227	6	1	3.0e-11	3.0e-11	1.0e+00	100	SIK2
73	12	47737273	49444545	3	2	8.9e-09	1.1e-08	1.6e-01	94	HDAC7 ZNF641
74	12	49780778	51256065	4	1	4.5e-11	3.7e-12	1.2e-09	23	CERS5
75	12	54158993	54760824	4	1	7.3e-12	1.2e-12	2.8e-03	82	FLJ12825
76	12	69057879	70476863	1	1	1.2e-08	1.8e-06	8.2e-01	100	YEATS4
77	12	89116708	90799212	3	1	9.5e-17	3.9e-25	4.9e-15	43	ATP2B1
78	12	109591369	111015121	2	1	1.1e-08	4.5e-08	8.0e-02	90	TCHP
79	12	111102574	113517494	14	1	3.0e-19	1.6e-27	2.9e-11	62	SH2B3
80	12	121146219	123131824	3	3	2.3e-14	5.6e-14	1.0e+00	100	KDM2B RNF34 WDR66
81	15	40360741	42749023	9	1	1.3e-11	9.8e-12	1.1e-01	94	CHP1
82	15	73933444	76108550	14	9	9.6e-22	2.7e-21	1.0e+00	100	ARID3B COX5A CSK MPI RPP25 UBL7 ULK3
83	15	80377452	81936479	2	1	1.6e-11	1.7e-14	1.6e-04	76	FAM108C1
84	15	90712555	92187978	3	3	6.1e-39	1.5e-28	1.0e+00	100	FES FURIN
85	16	3025993	5441125	5	3	8.2e-10	8.9e-09	6.5e-06	38	AC006111.1 MGRN1
86	16	29711343	31860399	15	2	4.5e-10	5.9e-09	5.3e-01	99	FAM57B KAT8
87	16	53226098	53759123	1	1	1.0e-07	1.3e-06	7.2e-01	99	RBL2
88	16	69337091	71292172	6	1	2.4e-08	1.6e-07	4.5e-01	98	RP11-296I10.6
89	16	74778006	76197034	1	1	2.5e-07	6.2e-06	2.7e-01	94	TMEM170A
90	16	81230341	81993974	1	1	4.1e-13	3.4e-13	5.6e-06	61	CMIP
91	16	89013848	90172696	11	1	2.0e-14	3.8e-14	3.0e-01	98	CHMP1A
92	17	1517914	2918626	1	1	3.0e-07	4.5e-08	1.8e-03	67	SRR
93	17	3208350	4766937	2	1	6.6e-10	3.7e-09	3.8e-01	98	RP11-810M2.2
94	17	6493198	8484683	10	3	6.3e-13	6.3e-13	1.0e+00	100	CYB5D1 SLC2A4 TNFSF12
95	17	42976114	43383100	1	1	5.6e-08	7.9e-07	4.6e-02	84	HEXIM1
96	17	44788310	45597098	1	1	1.9e-07	1.4e-11	2.1e-11	2	WNT3
97	17	46258510	47718188	7	2	2.3e-11	2.7e-14	2.6e-04	77	AC091133.1 ZNF652
98	17	60858059	62279811	2	1	9.4e-16	9.4e-16	1.0e+00	100	ACE
99	17	73175294	74629867	4	1	1.2e-08	8.5e-09	2.6e-01	96	FBF1
100	17	78665405	80023050	1	1	2.1e-07	8.0e-06	1.9e-04	30	RP11-1055B8.4
101	19	1163934	2560423	3	2	7.4e-10	4.3e-09	1.0e+00	100	CTB-31O20.6 KLF16
102	19	16045294	18007950	4	1	1.7e-12	5.8e-14	5.8e-05	71	MYO9B
103	19	48464978	49935001	4	1	2.7e-09	1.5e-08	4.0e-01	98	NTN5
104	20	7419920	9648826	1	2	2.1e-11	9.1e-19	4.7e-06	73	PLCB1
105	20	29927166	31469577	2	2	1.1e-08	7.6e-07	4.2e-05	31	C20orf160 TSPY26P
106	20	56858751	58262841	4	7	4.3e-18	2.5e-34	NaN	NaN	NELFCD TH1L TUBB1 ZNF831
107	20	61522825	62912463	8	10	2.2e-12	4.6e-12	1.0e+00	100	GMEB2 OPRL1 RGS19 TCEA2 UCKL1AS ZBTB46
108	21	44512286	45879403	2	1	2.3e-07	5.2e-08	1.7e-07	8	PDXK
109	22	28943477	29807855	3	1	4.1e-12	1.2e-08	2.9e-05	46	ZNRF3

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
Bipolar Disorder (2018)	1.88	1	0	0.0	0.00	1.0e+00	ZC3HC1
Bipolar Disorder or Schizophrenia	1.96	7	4	8.9	-0.46	2.5e-01	CERS5 CHMP1A FAM57B FES FURIN NT5C2 TBC1D19
Depressed Affect (Nagel 2018)	1.25	5	3	6.7	-0.51	3.8e-01	ACP2 OSGIN2 RP5-1115A15.1 SH2B3 WNT3
Depression (Nagel 2018)	1.23	1	0	0.0	0.00	1.0e+00	RP5-1115A15.1
Intelligence (Savage-Jansen 2018)	1.21	3	2	4.4	0.00	1.0e+00	DCAF16 GTF2B RBL2
Neuroticism (Nagel 2018)	1.16	5	2	4.4	-0.41	4.9e-01	ACP2 FURIN KAT8 RP5-1115A15.1 WNT3
Schizophrenia (2018)	1.81	4	3	6.7	-0.78	1.2e-01	FAM57B FES FURIN NT5C2
Worry (Nagel 2018)	1.27	2	2	4.4	0.00	1.0e+00	KAT8 NT5C2
Alzheimer’s Disease (including proxy)	1.44	4	2	4.4	-0.99	7.4e-03	ACE KAT8 PRKD3 PVRIG
Crohns Disease (2017)	1.41	3	2	4.4	0.00	1.0e+00	NTN5 PDLIM4 PMS2P5
Irritable Bowel Disease (IBD)	1.50	5	1	2.2	-0.82	8.9e-02	GMEB2 OPRL1 PDLIM4 PMS2P5 RGS19
Ulcerative Colitis (UC)	1.48	2	0	0.0	-0.29	6.4e-01	OPRL1 RGS19
Major Depression (MDD)	1.16	1	0	0.0	0.00	1.0e+00	FES
Reaction Time	1.12	1	1	2.2	0.00	1.0e+00	SH2B3
Verbal and Numeric Reasoning (VNR)	1.15	3	2	4.4	0.00	1.0e+00	DCAF16 RBL2 TEX15
Breast Cancer	2.25	12	3	6.7	0.50	5.9e-02	CSK FES FURIN LSP1 OPRL1 PDLIM4 PMS2P5 RGS19 RP11-1055B8.4 SIK2 SLC4A7 UBL7
Ovarian Cancer	1.27	2	0	0.0	0.00	1.0e+00	ABO WNT3
Prostate Cancer	1.36	1	0	0.0	0.00	1.0e+00	TNNT3
Body Mass Index (BMI) (2010)	1.77	1	0	0.0	0.00	1.0e+00	STAG3L1
Coronary Artery Disease (CAD)	2.07	2	2	4.4	0.00	1.0e+00	ABO MRAS
Crohns Disease (2012)	1.25	1	1	2.2	0.00	1.0e+00	PDLIM4
Fasting Glucose	1.63	1	1	2.2	0.00	1.0e+00	ACP2
HDL Cholesterol	1.44	4	1	2.2	-0.70	3.0e-01	ACP2 ADRB1 CTSW PIGV
LDL Cholesterol	1.81	4	1	2.2	-0.28	7.2e-01	ABO NTN5 PIGV SH2B3
Neuroticism (2016)	1.25	2	0	0.0	0.00	1.0e+00	MSRA NEIL2
Primary Biliary Cirrhosis	1.23	2	1	2.2	0.00	1.0e+00	CISD2 SH2B3
Rheumatoid Arthritis	1.31	2	0	0.0	0.00	1.0e+00	RGS19 SH2B3
Schizophrenia (2014)	1.78	6	3	6.7	-0.36	4.3e-01	CERS5 FAM57B FES FURIN NT5C2 RP5-1115A15.1
Triglycerides	1.45	3	0	0.0	0.00	1.0e+00	KAT8 NEIL2 NRBF2
Blood Eosinophil Count	3.57	23	17	37.8	0.59	2.9e-03	ABO ADRB2 CCDC36 CERS5 FAM57B FBF1 KAT8 NDUFAF6 NUCB2 PDLIM4 PDXK PIGV RP11-617D20.1 RP5-1115A15.1 SH2B3 SIK2 SIPA1 TCHP TSPY26P WNT3 ZC3HC1 ZNF652 ZNF831
Blood Platelet Count	2.91	43	34	75.6	-0.25	8.7e-02	ABCF3 AC091133.1 C20orf160 CAPZA1 CAST CERS5 CLCN6 COX5A CSK CTSW CWF19L2 DCAF16 FBF1 GMEB2 GTF2B HDAC7 HEXIM1 LFNG MGRN1 MPI MTHFR MYO9B NELFCD NRBF2 NTN5 NUCB2 PDLIM4 PHIP PIGV RHOC RP11-617D20.1 RPP25 SH2B3 SIK2 SLC4A7 SWAP70 TH1L TMEM170A TUBB1 UBL7 USP37 ZC3HC1 ZNF318
Blood Red Count	1.91	44	26	57.8	0.24	8.8e-02	ABO ARID3B BICC1 C20orf160 C4orf22 CENPW CHMP1A CLCN6 COX5A CSK CYB5D1 FAM57B FBF1 GMEB2 GTF2B HEXIM1 INPP5A IPO11 KAT8 MGRN1 MPI MTHFR NCOA1 NDUFAF6 NELFCD NPPA NPPA-AS1 NT5C2 PDXK PVRIG RP11-617D20.1 RPP25 SH2B3 SLC35F6 TDRD1 TH1L TSPY26P TUBB1 UBL7 ULK3 USP37 VEGFB WNT3 ZNF641
Blood White Count	1.93	30	14	31.1	0.57	7.3e-04	ABO ADRB2 C10orf118 CERS5 CMIP CYB5D1 DCAF16 FBF1 FES FLJ12825 FURIN GTF2B KB-1107E3.1 KCNK3 MGRN1 MOBP NRBF2 NT5C2 PDLIM4 PLCB1 RP11-617D20.1 RP5-1115A15.1 SGOL1 SH2B3 SRR TEX15 TMEM133 ULK3 VEGFB ZNF652
Heel T-Score	1.89	36	28	62.2	-0.13	4.4e-01	ABO ACP2 ATG7 BICC1 C20orf160 CAPZA1 CCDC36 CMIP CTSW CYB5D1 DCAF16 FAM57B GTF2B HEXIM1 INPP5A KAT8 LFNG NCOA1 NELFCD NT5C2 PMS2P5 RHOC RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 SIPA1 SOX6 STK32C TH1L TMEM133 TNFRSF25 TNFSF12 TUBB1 WNT3 ZNF318 ZNRF3
BMI	2.21	40	24	53.3	0.57	1.1e-04	AC006111.1 AC091133.1 C20orf160 C4orf22 CAST CEP41 CHP1 CISD2 CLCN6 COX5A CTB-31O20.6 CTSW FAM108C1 FAM57B FBF1 HSD17B12 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MRAS NRBF2 NT5C2 PDE1A PMS2P5 RGS19 RNF34 RP11-296I10.6 RP11-538P18.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25 TSPY26P USP37
Height	1.71	53	43	95.6	-0.34	1.4e-02	ABO AC006111.1 AC091133.1 ACE ACP2 ADRB1 ARID3B BICC1 CAPZA1 CENPW CERS5 CHP1 CTSW DBN1 DCAF16 EFR3B FAM57B FES FURIN GOPC GTF2B HEXIM1 HRCT1 LSP1 MGRN1 NCOA1 NT5C2 NTN5 NUCB2 PDLIM4 PIGV PTPN12 RBL2 RHOC RP11-1055B8.4 RP11-538P18.2 RP11-617D20.1 RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 SH2B3 SLC35F6 SLC4A7 STAG3L1 TMEM133 TMEM170A ULK3 USP37 WDR66 YEATS4 ZNF318 ZNF652 ZNF831
Waist Hip Ratio (WHR)	2.20	23	14	31.1	0.61	7.6e-04	CEP41 CMIP CTSW DBN1 FLJ12825 GTF2B MRAS MYO9B NCOA1 NTN5 OPRL1 PTPN12 RBL2 RGS19 SIK2 SIPA1 SWAP70 TBC1D19 TCEA2 VEGFB WNT3 ZNF318 ZNRF3
Systolic Blood Pressure	13.21	124	105	233.3	0.96	9.3e-82	ABCF3 AC006111.1 AC091133.1 ACE ACP2 ADRB1 ADRB2 AGT AKR1B1 ARID3B ATG7 ATP2B1 BICC1 C10orf118 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CCDC36 CENPW CERS5 CHP1 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTSW CWF19L2 CYB5D1 DCAF16 EFR3B ENPEP FAM108C1 FBF1 FCF1P2 FCN3 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HDAC7 HEXIM1 HOXA10 HRCT1 IPO11 KB-1107E3.1 KDM2B KLF16 LDB3 LFNG LSP1 MGRN1 MPI MRAS MTHFR MYO9B NCOA1 NDUFAF6 NEIL2 NELFCD NOC3L NPPA NPPA-AS1 NRBF2 NSUN6 NT5C2 NTN5 NUCB2 OPRL1 PDE1A PDXK PHIP PIGV PLCB1 PRDM8 PRKD3 PTPN12 RGS19 RHOC RNF34 RP11-1055B8.4 RP11-296I10.6 RP11-538P18.2 RP11-588K22.2 RP4-635E18.7 RP5-1115A15.1 RPP25 SH2B3 SIK2 SIPA1 SLC2A4 SLC4A7 SOX6 SRR STAG3L1 SWAP70 TBC1D19 TCEA2 TCHP TH1L TMEM133 TMEM170A TNFRSF25 TNFSF12 TNNT3 TUBB1 UBL7 UCKL1AS UFL1 ULK3 VEGFB WDR66 WNT3 ZBTB46 ZC3HC1 ZNF318 ZNF641 ZNF652 ZNF831 ZNRF3
Smoking Status	1.30	6	0	0.0	-0.16	7.3e-01	CTSW FAM108C1 FES RP5-1115A15.1 SRR ZNF652
Allergy or Eczema	2.06	13	5	11.1	0.26	4.0e-01	ABO CHP1 CLCN6 GMEB2 HDAC7 HEXIM1 NRBF2 PDLIM4 RNF34 RP5-1115A15.1 SIK2 SRR ZNF652
Cardiovascular Disease	13.49	142	117	260.0	0.99	4.0e-134	ABCF3 AC006111.1 AC091133.1 ACE ACP2 ADRB1 ADRB2 AGT AKR1B1 ARID3B ATG7 ATP2B1 BICC1 C10orf118 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CAST CCDC36 CENPW CEP41 CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTSW CWF19L2 CYB5D1 DBN1 DCAF16 EFR3B ENPEP EXOC4 FAM108C1 FAM57B FBF1 FCF1P2 FCN3 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HEXIM1 HOXA10 HRCT1 HSD17B12 IPO11 JARID2 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 LDB3 LFNG LSP1 MGRN1 MOBP MPI MRAS MTHFR MYO9B NCOA1 NDUFAF6 NELFCD NOC3L NPPA NPPA-AS1 NRBF2 NSUN6 NT5C2 NTN5 NUCB2 OPRL1 PDE1A PDXK PHIP PIGV PLCB1 PMS2P5 PRDM8 PTPN12 PVRIG RBL2 RGS19 RHOC RNF34 RP11-1055B8.4 RP11-296I10.6 RP11-538P18.2 RP11-588K22.2 RP11-617D20.1 RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 RPP25 SH2B3 SIK2 SIPA1 SLC2A4 SLC35F6 SLC4A7 SOX6 STAG3L1 SWAP70 TBC1D19 TCEA2 TCHP TDRD1 TEX15 TH1L TMEM133 TMEM170A TNFRSF25 TNFSF12 TNNT3 TSPY26P TUBB1 UBL7 UCKL1AS UFL1 ULK3 USP37 VEGFB WDR66 YEATS4 ZBTB46 ZC3HC1 ZNF318 ZNF641 ZNF652 ZNF831 ZNRF3
Hypothyroidism (self reported)	1.82	3	1	2.2	0.00	1.0e+00	NTN5 RP5-1115A15.1 SH2B3
Respiratory disease	1.73	9	3	6.7	0.58	1.0e-01	CHP1 FBF1 GMEB2 HDAC7 HEXIM1 PDLIM4 RP5-1115A15.1 SIK2 ZNF652
Type 2 Diabetes (T2D) (2018)	2.12	9	2	4.4	0.97	1.6e-05	ACE CTSW MRAS NDUFAF6 PMS2P5 RBL2 SH2B3 VEGFB ZBTB46
Lung FEV1/FVC ratio	1.84	27	15	33.3	-0.36	6.2e-02	ABO ATG7 ATP2B1 C1GALT1 CACNB2 CENPW CEP41 CTB-31O20.6 CYB5D1 FLJ12825 GOPC HDAC7 INPP5A KB-1107E3.1 NRBF2 NTN5 PDLIM4 PVRIG RP11-810M2.2 RP5-1115A15.1 STK32C TMEM133 TMEM170A TNFRSF25 TSPY26P WNT3 ZNF652
Lung FVC	1.68	17	11	24.4	-0.25	2.9e-01	C1GALT1 CHP1 DCAF16 FLJ12825 GMEB2 HOXA10 HSD17B12 KAT8 NCOA1 NRBF2 OPRL1 PDLIM4 RGS19 RP11-538P18.2 TNFRSF25 WNT3 ZBTB46
Neuroticism	1.15	4	2	4.4	-0.46	5.4e-01	FURIN NT5C2 RP5-1115A15.1 WNT3
Chronotype (morning person)	1.08	2	0	0.0	0.00	1.0e+00	RP11-810M2.2 RP5-1115A15.1
Hair Pigment	0.91	17	10	22.2	0.25	3.0e-01	ACP2 ATP2B1 C20orf160 C4orf22 CHMP1A CTSW FES OPRL1 PIGV RGS19 SH2B3 SIPA1 SOX6 TSPY26P WNT3 ZNF831 ZNRF3
Tanning	1.37	6	3	6.7	-0.28	5.9e-01	CHMP1A DBN1 NRBF2 SH2B3 TSPY26P UBL7
Hand grip strength (left)	1.44	6	2	4.4	-0.64	1.7e-01	DCAF16 FAM57B FES HEXIM1 MGRN1 PDLIM4
Number of treatments/medications taken	4.11	15	6	13.3	0.94	1.6e-07	AC091133.1 ACE CHP1 CISD2 DCAF16 FAM108C1 FES RP11-617D20.1 SH2B3 STK32C TMEM133 YEATS4 ZNF652 ZNF831 ZNRF3
Sensitivity / hurt feelings	1.38	4	3	6.7	-0.64	2.4e-01	AC091133.1 FES FURIN WNT3
Frequency of depressed mood in last 2 weeks	1.23	1	0	0.0	0.00	1.0e+00	RP5-1115A15.1
Hearing difficulty/problems: Yes	1.03	1	1	2.2	0.00	1.0e+00	ZNF318
Relative age of first facial hair	1.28	5	3	6.7	-0.74	1.6e-01	ATG7 C4orf22 HEXIM1 SIPA1 WNT3
Systolic blood pressure, automated reading	10.01	90	58	128.9	0.98	7.1e-66	AC006111.1 ACP2 ADRB1 ADRB2 AGT ATG7 ATP2B1 BICC1 C4orf22 CACNB2 CAPZA1 CCDC36 CERS5 CHP1 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTSW CWF19L2 DCAF16 FAM108C1 FAM57B FCF1P2 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HDAC7 HEXIM1 HOXA10 INPP5A IPO11 KLF16 LFNG LSP1 MGRN1 MPI MSRA MTHFR MYO9B NCOA1 NEIL2 NOC3L NPPA NPPA-AS1 NRBF2 NSUN6 NT5C2 NUCB2 OPRL1 PDE1A PHIP PIGV PMS2P5 PRKD3 RGS19 RHOC RP11-296I10.6 RP11-538P18.2 RP11-588K22.2 RP4-635E18.7 RP5-1115A15.1 RPP25 SH2B3 SLC2A4 SLC4A7 SOX6 SRR STAG3L1 SWAP70 TBC1D19 TCEA2 TCHP TH1L TMEM133 TMEM170A TNFSF12 TNNT3 UBL7 UFL1 ULK3 WNT3 ZBTB46 ZNF318 ZNF831 ZNRF3
Angina	2.93	5	3	6.7	0.96	6.6e-04	FES FURIN OPRL1 RGS19 ZNF652
Medication: Metformin	1.75	2	0	0.0	0.00	1.0e+00	CISD2 PMS2P5
Diabetes (father)	1.13	1	0	0.0	0.00	1.0e+00	AC091133.1
Pack years adult smoking proportion	1.31	1	0	0.0	0.00	1.0e+00	PMS2P5
Impedance of leg (right)	2.30	40	20	44.4	-0.03	8.7e-01	ABCF3 AC091133.1 ATG7 CEP41 CERS5 CTB-31O20.6 CTSW DBN1 FAM108C1 FAM57B FES FLJ12825 FURIN HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA MYO9B NEIL2 NELFCD NOC3L NT5C2 NUCB2 PDE1A PMS2P5 PRKD3 RBL2 RGS19 SLC35F6 SRR STAG3L1 SWAP70 TH1L TMEM133 USP37 WDR66 ZNF641 ZNF652
Leg fat-free mass (left)	1.92	27	15	33.3	0.19	3.5e-01	ABCF3 C10orf118 CENPW CTB-31O20.6 CTSW DBN1 DCAF16 FAM108C1 FAM57B FES FURIN HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SLC35F6 SRR STAG3L1 TDRD1 WDR66
Trunk fat percentage	1.99	27	11	24.4	0.67	1.5e-04	ABO AC091133.1 CHP1 CTB-31O20.6 CTSW FAM108C1 FAM57B FLJ12825 HOXA10 HSD17B12 KAT8 KCNK3 KDM2B MRAS MYO9B NOC3L RNF34 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 SRR STAG3L1 STK32C TEX15 TNFRSF25 TNFSF12 WNT3
Hand grip strength (right)	1.58	8	3	6.7	-0.66	7.4e-02	ABO CAPZA1 DCAF16 HEXIM1 JARID2 PDLIM4 RHOC UCKL1AS
Townsend deprivation index at recruitment	1.17	1	0	0.0	0.00	1.0e+00	KLF16
Current tobacco smoking	1.62	1	0	0.0	0.00	1.0e+00	MSRA
Maternal smoking around birth	1.19	1	0	0.0	0.00	1.0e+00	C20orf160
Fed-up feelings	1.25	3	1	2.2	0.00	1.0e+00	SH2B3 SLC2A4 TEX15
Relative age voice broke	1.14	1	0	0.0	0.00	1.0e+00	WNT3
Taking other prescription medications	2.04	4	2	4.4	1.00	1.8e-03	CISD2 PMS2P5 SH2B3 ZNF652
Age when periods started (menarche)	1.67	9	4	8.9	-0.05	9.0e-01	CCDC36 CTB-31O20.6 CTSW FAM57B HSD17B12 KLF16 NTN5 PMS2P5 STAG3L1
Heel bone mineral density (BMD) T-score, automated (left)	1.67	8	4	8.9	-0.21	6.2e-01	ACP2 CMIP CYB5D1 MSRA NEIL2 RP5-1115A15.1 SIPA1 ZNRF3
High blood pressure	14.82	154	139	308.9	1.00	1.0e-234	ABCF3 ABO AC006111.1 AC091133.1 ACE ACP2 ADRB1 ADRB2 AGT AKR1B1 ARID3B ATG7 ATP2B1 BICC1 C10orf118 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CAST CCDC36 CENPW CEP41 CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTSW CWF19L2 CYB5D1 DBN1 DCAF16 EFR3B ENPEP EXOC4 FAM108C1 FAM57B FBF1 FCF1P2 FCN3 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HDAC7 HEXIM1 HOXA10 HRCT1 HSD17B12 INPP5A IPO11 JARID2 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 LDB3 LFNG LSP1 MGRN1 MOBP MPI MRAS MSRA MTHFR MYO9B NCOA1 NDUFAF6 NEIL2 NELFCD NOC3L NPPA NPPA-AS1 NRBF2 NSUN6 NT5C2 NTN5 NUCB2 OPRL1 OSGIN2 PDE1A PDLIM4 PDXK PHIP PIGV PLCB1 PMS2P5 PRDM8 PRKD3 PTPN12 PVRIG RBL2 RGS19 RHOC RNF34 RP11-1055B8.4 RP11-296I10.6 RP11-538P18.2 RP11-588K22.2 RP11-617D20.1 RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 RPP25 SGOL1 SH2B3 SIK2 SIPA1 SLC2A4 SLC35F6 SLC4A7 SOX6 SRR STAG3L1 STK32C SWAP70 TBC1D19 TCEA2 TCHP TDRD1 TEX15 TH1L TMEM133 TMEM170A TNFRSF25 TNFSF12 TNNT3 TSPY26P TUBB1 UBL7 UCKL1AS UFL1 ULK3 USP37 VEGFB WDR66 WNT3 YEATS4 ZBTB46 ZC3HC1 ZNF318 ZNF641 ZNF652 ZNF831 ZNRF3
Hayfever, allergic rhinitis or eczema	1.96	5	5	11.1	0.57	3.1e-01	CHP1 PDLIM4 RP5-1115A15.1 SIK2 ZNF652
Supplements: Glucosamine	1.59	2	1	2.2	0.00	1.0e+00	CSK NRBF2
Medication: Atenolol	5.41	7	2	4.4	0.99	4.3e-06	CLCN6 FES FURIN PRKD3 RHOC SH2B3 TMEM133
Medication: Levothyroxine sodium	1.68	2	1	2.2	0.00	1.0e+00	MSRA SH2B3
Sitting height	1.44	25	14	31.1	-0.17	4.1e-01	AC091133.1 ADRB1 C10orf118 C20orf160 CENPW CERS5 CHP1 DCAF16 FCN3 GOPC GTF2B HEXIM1 JARID2 NTN5 PDLIM4 RBL2 RP11-538P18.2 SLC35F6 SLC4A7 WDR66 WNT3 ZNF641 ZNF652 ZNF831 ZNRF3
High blood pressure (mother)	5.55	14	4	8.9	0.96	4.3e-10	AGT CENPW CHMP1A CLCN6 FES FLJ12825 FURIN HOXA10 LSP1 NT5C2 PIGV SLC4A7 TNFRSF25 ZNF831
Body mass index (BMI)	2.35	30	18	40.0	0.78	2.9e-07	AC091133.1 CAST CEP41 COX5A CTB-31O20.6 CTSW DCAF16 FAM108C1 FAM57B HSD17B12 KAT8 KCNK3 KDM2B KLF16 MSRA NEIL2 NRBF2 NT5C2 PDE1A PMS2P5 RP11-296I10.6 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25 USP37
Impedance of leg (left)	2.31	37	22	48.9	-0.07	6.5e-01	ABCF3 AC091133.1 ATG7 CEP41 CERS5 CTB-31O20.6 CTSW DBN1 FAM108C1 FAM57B FES FLJ12825 FURIN HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA MYO9B NEIL2 NELFCD NOC3L NT5C2 NUCB2 PMS2P5 PRKD3 RBL2 RGS19 RP11-296I10.6 SLC35F6 SRR STAG3L1 SWAP70 TMEM133 USP37 ZNF652
Leg predicted mass (left)	1.92	27	15	33.3	0.15	4.7e-01	ABCF3 C10orf118 CENPW CTSW DBN1 DCAF16 FAM108C1 FAM57B FES FURIN HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA MYO9B NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SLC35F6 SRR STAG3L1 TDRD1 WDR66
Trunk fat mass	1.96	24	9	20.0	0.65	5.7e-04	CAST CTB-31O20.6 CTSW FAM108C1 FAM57B HOXA10 HSD17B12 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MRAS NT5C2 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25
Waist circumference	2.26	26	12	26.7	0.70	6.3e-05	CMIP COX5A CTB-31O20.6 CTSW EFR3B EXOC4 FAM108C1 FAM57B HSD17B12 KAT8 KB-1107E3.1 KCNK3 KLF16 MPI NRBF2 PHIP RP11-296I10.6 RP11-810M2.2 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25 UBL7
Number of incorrect matches in round	1.41	4	1	2.2	-1.00	2.6e-06	FAM57B FES FURIN KAT8
Past tobacco smoking	1.26	1	0	0.0	0.00	1.0e+00	SH2B3
Alcohol usually taken with meals	1.23	1	0	0.0	0.00	1.0e+00	FES
Nervous feelings	1.32	3	1	2.2	0.00	1.0e+00	KAT8 MSRA NT5C2
Frequency of tenseness / restlessness in last 2 weeks	1.14	1	0	0.0	0.00	1.0e+00	NT5C2
Hearing difficulty/problems with background noise	1.52	4	2	4.4	-0.99	8.3e-03	CSK UBL7 ULK3 ZNF318
Hair/balding pattern: Pattern 2	1.51	2	1	2.2	0.00	1.0e+00	C4orf22 PRDM8
Had menopause	1.04	1	0	0.0	0.00	1.0e+00	CHP1
Forced vital capacity (FVC)	1.71	11	6	13.3	-0.36	2.8e-01	CAPZA1 CENPW DCAF16 GMEB2 KAT8 NCOA1 RBL2 RHOC RP11-538P18.2 WDR66 WNT3
Heel bone mineral density (BMD) T-score, automated (right)	1.65	7	5	11.1	-0.17	7.2e-01	ACP2 CYB5D1 MSRA NEIL2 RP5-1115A15.1 SIPA1 ZNRF3
Qualifications: None of the above	1.35	2	1	2.2	0.00	1.0e+00	PHIP RBL2
Mouth/teeth dental problems	1.41	2	0	0.0	0.00	1.0e+00	NTN5 PMS2P5
Heart attack	2.53	3	1	2.2	0.00	1.0e+00	FES ZC3HC1 ZNF652
Allergy	2.22	10	6	13.3	-0.19	6.1e-01	ABO CHP1 FES GMEB2 HDAC7 HEXIM1 PDLIM4 RP5-1115A15.1 SIK2 ZNF652
Diabetes (self-reported)	1.94	3	1	2.2	0.00	1.0e+00	PMS2P5 RBL2 ZBTB46
Medication: Ramipril	4.77	8	2	4.4	0.98	2.9e-05	CISD2 CMIP CSK FES GOPC LSP1 TMEM133 ZC3HC1
Medication: Simvastatin	4.22	10	4	8.9	0.76	1.5e-03	ABO DCAF16 FES NTN5 OPRL1 PIGV RGS19 VEGFB YEATS4 ZNF831
Fluid intelligence score	1.17	2	2	4.4	0.00	1.0e+00	DCAF16 RBL2
Illnesses of siblings	3.88	7	2	4.4	-0.98	1.4e-06	CLCN6 FES KAT8 NRBF2 RBL2 SH2B3 TMEM133
Neuroticism score	1.18	4	3	6.7	-0.99	1.1e-02	MSRA NEIL2 RP5-1115A15.1 WNT3
Weight	2.00	30	16	35.6	0.44	1.5e-02	C10orf118 CAST CTB-31O20.6 CTSW DCAF16 EFR3B EXOC4 FAM108C1 FAM57B HSD17B12 KAT8 KB-1107E3.1 KCNK3 KLF16 MRAS MSRA NEIL2 NT5C2 PDE1A PDLIM4 RBL2 RP11-296I10.6 RP11-810M2.2 RPP25 SH2B3 SRR STAG3L1 STK32C TDRD1 WDR66
Impedance of arm (right)	2.05	31	14	31.1	-0.45	1.1e-02	ABO ARID3B CCDC36 CERS5 CISD2 CMIP CTB-31O20.6 CTSW FAM57B FLJ12825 HEXIM1 HOXA10 HSD17B12 KAT8 KLF16 LSP1 MSRA MYO9B NEIL2 NOC3L NRBF2 NUCB2 PDE1A RGS19 SLC4A7 STAG3L1 TNFSF12 TSPY26P UCKL1AS ZNF641 ZNF652
Arm fat percentage (right)	2.20	30	17	37.8	0.66	7.8e-05	ABO AC091133.1 CHP1 COX5A CTB-31O20.6 CTSW DCAF16 FAM108C1 FAM57B FBF1 HOXA10 HSD17B12 KAT8 KCNK3 KDM2B KLF16 MSRA NT5C2 PMS2P5 RNF34 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 SLC2A4 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25
Trunk fat-free mass	1.86	25	18	40.0	0.01	9.5e-01	ABO C10orf118 CENPW DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 JARID2 KAT8 KCNK3 KLF16 MYO9B NCOA1 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 SLC4A7 TMEM133 WDR66
Hip circumference	2.14	29	12	26.7	0.17	3.6e-01	CAST CLCN6 CTB-31O20.6 FAM108C1 FAM57B FBF1 HSD17B12 KAT8 KB-1107E3.1 KCNK3 KLF16 MRAS MSRA NPPA NPPA-AS1 NT5C2 PDE1A PHIP PMS2P5 RBL2 RGS19 RP11-296I10.6 RP11-810M2.2 SH2B3 SRR STAG3L1 STK32C VEGFB WDR66
Alcohol intake versus 10 years previously	1.15	2	0	0.0	0.00	1.0e+00	FAM57B NTN5
Father's age at death	2.27	3	2	4.4	0.00	1.0e+00	ABO FES SH2B3
Worrier / anxious feelings	1.51	4	1	2.2	-0.59	4.1e-01	KAT8 MSRA NEIL2 NT5C2
Frequency of tiredness / lethargy in last 2 weeks	1.37	3	1	2.2	0.00	1.0e+00	AC091133.1 CCDC36 RP5-1115A15.1
Hair/balding pattern: Pattern 3	1.76	4	2	4.4	0.71	2.9e-01	C4orf22 HEXIM1 PRDM8 WNT3
Forced expiratory volume in 1-second (FEV1)	1.77	13	3	6.7	-0.30	3.1e-01	ABO DCAF16 GOPC KAT8 MSRA NCOA1 NRBF2 PDLIM4 RHOC RP11-538P18.2 TMEM133 TSPY26P WNT3
Pulse rate	1.03	1	0	0.0	0.00	1.0e+00	RBL2
Qualifications: A levels/AS levels or equivalent	1.25	2	0	0.0	0.00	1.0e+00	RBL2 STAG3L1
Serious illness, injury or assault of a close relative in last 2 years	1.17	1	0	0.0	0.00	1.0e+00	NTN5
Mouth/teeth dental problems: Dentures	1.22	2	1	2.2	0.00	1.0e+00	NTN5 RP11-1055B8.4
Asthma	1.89	5	4	8.9	0.63	2.6e-01	HDAC7 PDLIM4 RP5-1115A15.1 SIK2 ZNF652
Medication: Cholesterol lowering	4.20	13	5	11.1	0.85	1.6e-05	ABO CHP1 CLCN6 FES NTN5 OPRL1 PIGV PVRIG RGS19 TMEM133 TNFRSF25 YEATS4 ZNF831
Depression (self-reported)	1.05	1	0	0.0	0.00	1.0e+00	RP5-1115A15.1
Illnesses of mother	3.65	1	1	2.2	0.00	1.0e+00	FES
Forced expiratory volume in 1-second (FEV1), Best measure	1.69	9	5	11.1	-0.24	5.3e-01	ABO DCAF16 KAT8 NCOA1 NRBF2 PDLIM4 RP11-538P18.2 TMEM133 WNT3
Pulse wave Arterial Stiffness index	1.84	1	0	0.0	0.00	1.0e+00	VEGFB
Impedance of arm (left)	2.09	31	17	37.8	-0.39	3.2e-02	ABO ARID3B CCDC36 CERS5 CISD2 CMIP CTSW FAM108C1 FAM57B FLJ12825 HEXIM1 HOXA10 HSD17B12 KAT8 LSP1 MSRA MYO9B NEIL2 NOC3L NRBF2 PDE1A PRKD3 RGS19 SH2B3 SLC4A7 STAG3L1 TNFSF12 TSPY26P UCKL1AS ZNF641 ZNF652
Arm fat mass (right)	2.19	28	13	28.9	0.69	4.1e-05	AC091133.1 CAST COX5A CTB-31O20.6 CTSW EFR3B FAM108C1 FAM57B HOXA10 HSD17B12 KAT8 KCNK3 KDM2B KLF16 MSRA NT5C2 PDE1A PMS2P5 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25
Trunk predicted mass	1.86	24	17	37.8	0.05	8.3e-01	ABO C10orf118 CENPW DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 JARID2 KAT8 KCNK3 KLF16 MYO9B NCOA1 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 SLC4A7 WDR66
Standing height	1.66	42	25	55.6	-0.29	6.3e-02	AC006111.1 AC091133.1 ACP2 ADRB1 C10orf118 CAPZA1 CENPW CERS5 CHP1 DBN1 DCAF16 EFR3B FAM57B GOPC GTF2B HEXIM1 LSP1 MGRN1 MSRA NCOA1 NUCB2 PDLIM4 PIGV PTPN12 RBL2 RHOC RP11-1055B8.4 RP11-538P18.2 RP11-617D20.1 RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 SH2B3 SLC35F6 SLC4A7 TMEM170A ULK3 USP37 WDR66 ZNF318 ZNF652 ZNF831
Tense / 'highly strung'	1.10	3	0	0.0	0.00	1.0e+00	KAT8 NT5C2 RP5-1115A15.1
Hair/balding pattern: Pattern 4	2.04	8	6	13.3	0.49	2.2e-01	C4orf22 CENPW CERS5 HEXIM1 PRDM8 RP5-1115A15.1 SRR WNT3
Birth weight of first child	3.32	15	4	8.9	-0.98	1.9e-13	CLCN6 COX5A CSK DCAF16 FES FURIN GTF2B MTHFR NPPA-AS1 OPRL1 RGS19 RPP25 SH2B3 STAG3L1 TMEM170A
Peak expiratory flow (PEF)	1.71	8	4	8.9	-0.61	1.1e-01	ABO C1GALT1 DCAF16 MSRA NTN5 SLC2A4 TMEM170A WNT3
Pulse wave reflection index	1.30	2	0	0.0	0.00	1.0e+00	FLJ12825 INPP5A
Blood clot in the leg (DVT)	2.96	1	1	2.2	0.00	1.0e+00	ABO
Medication: Paracetamol	1.67	1	0	0.0	0.00	1.0e+00	UFL1
Headache pain in last month	1.51	3	1	2.2	0.00	1.0e+00	TMEM170A UFL1 WNT3
Medication for cholesterol, blood pressure or diabetes	8.17	37	14	31.1	-0.98	5.4e-33	ACE ATP2B1 C1GALT1 C4orf22 CHP1 CISD2 CLCN6 CSK CTSW FAM108C1 FCF1P2 FES FURIN JARID2 LFNG MTHFR OPRL1 OSGIN2 PDXK PLCB1 PVRIG RGS19 RHOC RP11-296I10.6 RP11-588K22.2 SH2B3 SIK2 SLC4A7 TH1L TMEM133 TNFRSF25 TSPY26P ULK3 YEATS4 ZBTB46 ZNF652 ZNF831
Gout (self-reported)	1.58	2	0	0.0	0.00	1.0e+00	SH2B3 SIPA1
Hypothyroidism/myxoedema (self-reported)	1.65	3	1	2.2	0.00	1.0e+00	MSRA RP5-1115A15.1 SH2B3
Medication: Amlodipine	6.19	19	9	20.0	0.95	1.8e-12	CAPZA1 CLCN6 FAM108C1 FES KCNK3 KDM2B LSP1 MTHFR NPPA-AS1 OSGIN2 RHOC RNF34 RP11-617D20.1 RP4-635E18.7 SLC35F6 TMEM133 TNFSF12 TNNT3 ZNF318
Medication: Ventolin 100micrograms inhaler	1.30	1	0	0.0	0.00	1.0e+00	ZNF652
Birth weight	2.73	13	9	20.0	-0.58	2.9e-02	ADRB1 DBN1 DCAF16 FES FURIN NTN5 SH2B3 SIK2 SLC2A4 SRR TNNT3 UCKL1AS ZNRF3
High blood pressure (siblings)	4.96	9	4	8.9	0.98	2.1e-08	ACP2 CLCN6 FES KAT8 NPPA NRBF2 RHOC SH2B3 TMEM133
Forced vital capacity (FVC), Best measure	1.57	11	5	11.1	-0.44	1.7e-01	ACP2 CENPW DBN1 DCAF16 GMEB2 KAT8 NCOA1 RBL2 RHOC RP11-538P18.2 WNT3
Body fat percentage	2.11	30	11	24.4	0.61	3.9e-04	ABO AC091133.1 CAST CHP1 COX5A CTB-31O20.6 CTSW DCAF16 FAM108C1 FAM57B FLJ12825 HOXA10 HSD17B12 KAT8 KCNK3 KDM2B MRAS MYO9B NOC3L PMS2P5 RNF34 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TEX15 TNFRSF25
Leg fat percentage (right)	2.21	23	12	26.7	0.82	1.4e-06	CHP1 COX5A CTB-31O20.6 CTSW DCAF16 FAM108C1 FAM57B GTF2B HSD17B12 KAT8 KCNK3 KDM2B MOBP MSRA NOC3L RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 STAG3L1 STK32C TEX15 TNFRSF25
Arm fat-free mass (right)	1.88	23	13	28.9	0.17	4.3e-01	ABO C10orf118 CENPW CTSW DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MYO9B NEIL2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 STAG3L1 WDR66
Comparative body size at age 10	1.65	11	6	13.3	0.34	3.1e-01	ATG7 CERS5 EFR3B FAM57B FCF1P2 KAT8 MSRA NTN5 SIPA1 SRR ZNF652
Worry too long after embarrassment	1.10	1	0	0.0	0.00	1.0e+00	MSRA
Seen a psychiatrist for nerves, anxiety, tension or depression	1.37	1	0	0.0	0.00	1.0e+00	ADRB1
Wheeze or whistling in the chest in last year	1.67	3	0	0.0	0.00	1.0e+00	GMEB2 SIK2 ZNF652
Qualifications: College or University degree	1.12	8	2	4.4	-0.75	3.1e-02	DCAF16 FAM57B GTF2B RBL2 STAG3L1 TEX15 TNFRSF25 WNT3
Medication for pain relief, constipation, heartburn	1.95	6	2	4.4	-0.98	5.4e-04	ACE C20orf160 FAM108C1 STK32C UFL1 YEATS4
Neck or shoulder pain in last month	1.42	1	0	0.0	0.00	1.0e+00	RP5-1115A15.1
Medication: Blood pressure	10.31	68	28	62.2	0.99	1.3e-63	AC091133.1 ACE ACP2 ADRB1 ATP2B1 BICC1 C1GALT1 C20orf160 C4orf22 CAPZA1 CEP41 CHMP1A CISD2 CLCN6 CMIP CSK CTSW CWF19L2 CYB5D1 DCAF16 EFR3B FAM108C1 FAM57B FCF1P2 FES FURIN HOXA10 JARID2 KDM2B KLF16 LDB3 LFNG LSP1 MOBP MSRA MTHFR NELFCD NOC3L NPPA NPPA-AS1 OSGIN2 PDXK PLCB1 PRDM8 PVRIG RGS19 RHOC RNF34 RP11-810M2.2 RP4-635E18.7 SH2B3 SIK2 SIPA1 SLC2A4 SLC4A7 SOX6 STAG3L1 TH1L TMEM133 TNNT3 TSPY26P ULK3 WDR66 ZBTB46 ZC3HC1 ZNF318 ZNF652 ZNF831
Angina (self-reported)	2.91	5	1	2.2	0.97	3.9e-04	FES FURIN OPRL1 RGS19 ZNF652
Migraine (self-reported)	1.28	1	1	2.2	0.00	1.0e+00	UFL1
Medication: Allopurinol	1.58	3	0	0.0	0.00	1.0e+00	CYB5D1 SH2B3 WDR66
Medication: Seretide 50 evohaler	1.36	2	0	0.0	0.00	1.0e+00	PDLIM4 ZNF652
Mean time to correctly identify matches	1.15	2	1	2.2	0.00	1.0e+00	RP11-810M2.2 SH2B3
Whole body fat mass	2.04	28	14	31.1	0.65	2.0e-04	AC091133.1 CAST COX5A CTB-31O20.6 CTSW FAM108C1 FAM57B HOXA10 HSD17B12 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MRAS MSRA NT5C2 PMS2P5 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25
Leg fat mass (right)	2.14	25	12	26.7	0.85	1.0e-07	AC091133.1 CAST CTB-31O20.6 CTSW FAM108C1 FAM57B HSD17B12 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MOBP MRAS MSRA PMS2P5 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 STAG3L1 STK32C TEX15 TNFRSF25 TSPY26P
Arm predicted mass (right)	1.87	24	12	26.7	0.20	3.4e-01	ABO C10orf118 CENPW CMIP DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MYO9B NEIL2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 STAG3L1 TSPY26P WDR66
Pulse rate, automated reading	1.32	6	2	4.4	-0.07	8.9e-01	ABO ACP2 CCDC36 PVRIG RBL2 SIK2
Alcohol intake frequency.	1.60	7	3	6.7	0.69	8.7e-02	ARID3B FAM57B KAT8 NTN5 PMS2P5 TEX15 ZNF318
Comparative height size at age 10	1.57	19	10	22.2	-0.21	3.8e-01	CENPW DBN1 DCAF16 FAM108C1 FAM57B FES GTF2B NCOA1 NTN5 NUCB2 PDLIM4 PIGV RBL2 RP11-617D20.1 RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 SH2B3 WDR66
Number of full sisters	1.37	1	0	0.0	0.00	1.0e+00	NRBF2
Suffer from 'nerves'	1.14	1	0	0.0	0.00	1.0e+00	RP5-1115A15.1
Overall health rating	2.15	11	5	11.1	0.99	1.3e-09	AC091133.1 CTSW DCAF16 HEXIM1 KAT8 MSRA PMS2P5 RBL2 TEX15 TSPY26P ZNF652
Had major operations	1.22	1	0	0.0	0.00	1.0e+00	ZNF652
Medication: Aspirin	3.97	6	1	2.2	0.95	1.1e-04	AC091133.1 FES GOPC OPRL1 RGS19 SIK2
Knee pain experienced in last month	1.51	1	0	0.0	0.00	1.0e+00	ARID3B
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.27	1	0	0.0	0.00	1.0e+00	KDM2B
Illnesses of father: Heart disease	2.55	3	1	2.2	0.74	2.6e-01	ABO FES RGS19
Smoking status: Previous	1.10	1	0	0.0	0.00	1.0e+00	SH2B3
Forced expiratory volume in 1-second (FEV1), predicted	1.31	4	2	4.4	-0.95	4.5e-02	DCAF16 HEXIM1 MGRN1 PDLIM4
Whole body fat-free mass	1.90	23	17	37.8	0.08	7.3e-01	C10orf118 CENPW DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MYO9B NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 SLC4A7 STAG3L1 WDR66
Leg fat-free mass (right)	1.95	28	16	35.6	0.07	7.1e-01	ABCF3 C10orf118 CENPW CTSW DBN1 DCAF16 FAM108C1 FAM57B FES FURIN HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA MYO9B NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 SRR STAG3L1 TDRD1 WDR66
Arm fat percentage (left)	2.19	27	18	40.0	0.70	4.5e-05	ABO AC091133.1 CHP1 COX5A CTB-31O20.6 CTSW DCAF16 FAM108C1 FAM57B FBF1 HOXA10 HSD17B12 KAT8 KCNK3 KDM2B KLF16 MSRA PMS2P5 RNF34 RP11-296I10.6 RP5-1115A15.1 SLC2A4 SRR STAG3L1 STK32C TEX15 TNFRSF25
Average weekly red wine intake	1.27	1	0	0.0	0.00	1.0e+00	MPI
Mood swings	1.24	3	0	0.0	0.00	1.0e+00	ACP2 OSGIN2 WNT3
Loneliness, isolation	1.36	1	0	0.0	0.00	1.0e+00	RP5-1115A15.1
Long-standing illness, disability or infirmity	1.88	3	0	0.0	0.00	1.0e+00	CHP1 PMS2P5 ZNF652
Ever had bowel cancer screening	1.16	1	0	0.0	0.00	1.0e+00	SIK2
Diabetes diagnosed by doctor	2.19	5	2	4.4	1.00	1.6e-04	CTSW MRAS PMS2P5 RBL2 ZBTB46
Mouth/teeth dental problems: Mouth ulcers	1.41	1	0	0.0	0.00	1.0e+00	OSGIN2
Medication for cholesterol	6.77	26	8	17.8	-0.97	1.4e-16	ATG7 C4orf22 CAPZA1 CENPW CHMP1A CISD2 CMIP FES HOXA10 JARID2 KAT8 LSP1 MGRN1 NTN5 PIGV PLCB1 PRKD3 RBL2 RGS19 RHOC SH2B3 TMEM133 VEGFB ZBTB46 ZNF831 ZNRF3
Back pain experienced in last month	1.60	1	0	0.0	0.00	1.0e+00	WDR66
Mineral and other dietary supplements	1.30	1	0	0.0	0.00	1.0e+00	NRBF2
Breast cancer (self-reported)	1.42	1	0	0.0	0.00	1.0e+00	SLC4A7
Asthma (self-reported)	1.84	6	4	8.9	0.43	4.0e-01	FBF1 HDAC7 PDLIM4 RP5-1115A15.1 SIK2 ZNF652
Osteoarthritis (self-reported)	1.64	2	0	0.0	0.00	1.0e+00	COX5A RPP25
Medication: Aspirin	4.14	5	1	2.2	0.93	6.7e-04	FES OPRL1 RGS19 SIK2 VEGFB
Illnesses of father: None of the above (group 1)	2.62	2	1	2.2	0.00	1.0e+00	FES SH2B3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.68	5	3	6.7	-0.22	7.2e-01	KAT8 NRBF2 RP11-538P18.2 TMEM170A WNT3
Whole body water mass	1.91	23	17	37.8	0.07	7.4e-01	C10orf118 CENPW DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA MYO9B NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 STAG3L1 WDR66
Leg predicted mass (right)	1.94	27	16	35.6	0.05	8.1e-01	ABCF3 C10orf118 CENPW DBN1 DCAF16 FAM108C1 FAM57B FES FURIN HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA MYO9B NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 SRR STAG3L1 TDRD1 WDR66
Arm fat mass (left)	2.15	29	12	26.7	0.61	4.5e-04	AC091133.1 CAST COX5A CTB-31O20.6 CTSW EFR3B FAM108C1 FAM57B FBF1 HOXA10 HSD17B12 KAT8 KCNK3 KDM2B KLF16 MRAS MSRA NT5C2 PMS2P5 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25
Number of self-reported non-cancer illnesses	4.96	16	6	13.3	0.97	1.4e-12	CISD2 CLCN6 CYB5D1 GMEB2 HDAC7 MYO9B NTN5 OPRL1 PDLIM4 PMS2P5 RGS19 SH2B3 ZNF318 ZNF652 ZNF831 ZNRF3
Miserableness	1.15	3	0	0.0	0.00	1.0e+00	ACP2 RP5-1115A15.1 WNT3
Eye problems/disorders: Glaucoma	1.22	1	0	0.0	0.00	1.0e+00	TEX15
Medication: Blood pressure	11.08	89	39	86.7	0.99	9.7e-76	ACE ACP2 ADRB1 AGT AKR1B1 ARID3B ATG7 ATP2B1 C1GALT1 C4orf22 CACNB2 CAPZA1 CENPW CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTSW CWF19L2 CYB5D1 FAM108C1 FCF1P2 FES FLJ12825 FURIN GMEB2 GTF2B HEXIM1 HOXA10 HRCT1 KAT8 KB-1107E3.1 KCNK3 KDM2B LFNG LSP1 MGRN1 MPI MRAS MSRA MTHFR MYO9B NCOA1 NEIL2 NPPA NRBF2 NSUN6 NT5C2 NTN5 OPRL1 PDLIM4 PDXK PIGV PLCB1 PRKD3 PTPN12 RGS19 RHOC RNF34 RP11-1055B8.4 RP11-588K22.2 RP11-810M2.2 RP4-635E18.7 RPP25 SH2B3 SIK2 SIPA1 SLC2A4 SLC35F6 SLC4A7 TBC1D19 TDRD1 TEX15 TMEM133 TNFSF12 TNNT3 UBL7 UCKL1AS ULK3 VEGFB WNT3 ZBTB46 ZNF318 ZNF831 ZNRF3
Supplements: Fish oil (including cod liver oil)	1.07	1	0	0.0	0.00	1.0e+00	HEXIM1
High cholesterol (Self-reported)	3.74	10	7	15.6	0.61	2.0e-02	ABO CLCN6 DCAF16 FBF1 NTN5 OPRL1 PIGV RGS19 TMEM133 VEGFB
Medication: Bendroflumethiazide	7.33	33	11	24.4	0.97	5.1e-22	ABCF3 ACP2 ADRB1 AGT ATP2B1 CACNB2 CAPZA1 CHMP1A CLCN6 CSK FAM108C1 FAM57B FES HOXA10 KAT8 LSP1 MGRN1 MYO9B NEIL2 NRBF2 NTN5 PDLIM4 PIGV PLCB1 RHOC SH2B3 SLC35F6 SLC4A7 TEX15 TMEM133 TNFSF12 USP37 ZNF831
Medication: Paracetamol	1.72	1	0	0.0	0.00	1.0e+00	UFL1
Medication: Lisinopril	4.55	6	0	0.0	0.98	5.5e-04	ACP2 CSK FCF1P2 LSP1 NRBF2 ZNF831
Medication: Atorvastatin	2.09	1	0	0.0	0.00	1.0e+00	ABO
Illnesses of father: High blood pressure	4.31	6	1	2.2	0.99	1.0e-05	ACE C4orf22 CHMP1A FES NCOA1 PLCB1
Ever smoked	1.28	2	0	0.0	0.00	1.0e+00	SH2B3 SRR
Basal metabolic rate	1.91	23	17	37.8	0.18	4.0e-01	C10orf118 CENPW CTSW DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 STAG3L1 WDR66
Leg fat percentage (left)	2.23	23	10	22.2	0.82	1.7e-06	CHP1 COX5A CTB-31O20.6 CTSW DCAF16 FAM108C1 FAM57B GTF2B HSD17B12 KAT8 KCNK3 KDM2B MOBP MSRA PMS2P5 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 STAG3L1 STK32C TEX15 TNFRSF25
Arm fat-free mass (left)	1.87	26	13	28.9	0.31	1.3e-01	ABO C10orf118 CENPW CMIP CTSW DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA NEIL2 NT5C2 PDE1A PDLIM4 RBL2 RP11-810M2.2 SH2B3 SLC35F6 STAG3L1 TSPY26P WDR66
Irritability	1.28	3	3	6.7	0.00	1.0e+00	CCDC36 MSRA NEIL2
Risk taking	1.25	2	0	0.0	0.00	1.0e+00	KCNK3 STK32C
Diastolic blood pressure, automated reading	9.02	84	53	117.8	0.97	9.8e-60	ABO AC006111.1 AC091133.1 ACE ACP2 ADRB1 AGT ATP2B1 C10orf118 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CENPW CEP41 CERS5 CHP1 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTSW CWF19L2 CYB5D1 DCAF16 ENPEP FAM108C1 FCF1P2 FES FURIN GMEB2 HDAC7 HEXIM1 HOXA10 HRCT1 IPO11 KAT8 LFNG LSP1 MPI MSRA MTHFR MYO9B NCOA1 NDUFAF6 NEIL2 NELFCD NOC3L NPPA NPPA-AS1 NRBF2 NSUN6 NT5C2 PDLIM4 PHIP PIGV PMS2P5 PVRIG RGS19 RHOC RP11-296I10.6 RP11-538P18.2 RP5-1115A15.1 RPP25 SH2B3 SIPA1 SLC2A4 SRR STAG3L1 SWAP70 TBC1D19 TCEA2 TCHP TH1L TMEM133 TNFSF12 TUBB1 UBL7 ULK3 ZC3HC1 ZNF652 ZNF831
Myopia	1.21	1	0	0.0	0.00	1.0e+00	CAPZA1
Vascular/heart problems diagnosed by doctor	14.42	153	114	253.3	-1.00	1.6e-176	ABCF3 ABO AC006111.1 AC091133.1 ACE ACP2 ADRB1 ADRB2 AGT AKR1B1 ARID3B ATG7 ATP2B1 BICC1 C10orf118 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CAST CCDC36 CENPW CEP41 CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTSW CWF19L2 CYB5D1 DCAF16 EFR3B ENPEP EXOC4 FAM108C1 FAM57B FBF1 FCF1P2 FCN3 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HDAC7 HEXIM1 HOXA10 HRCT1 HSD17B12 INPP5A IPO11 JARID2 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 LDB3 LFNG LSP1 MGRN1 MOBP MPI MRAS MSRA MTHFR MYO9B NCOA1 NDUFAF6 NEIL2 NELFCD NOC3L NPPA NPPA-AS1 NRBF2 NSUN6 NT5C2 NTN5 NUCB2 OPRL1 OSGIN2 PDE1A PDLIM4 PDXK PHIP PIGV PLCB1 PMS2P5 PRDM8 PRKD3 PTPN12 PVRIG RBL2 RGS19 RHOC RNF34 RP11-1055B8.4 RP11-296I10.6 RP11-538P18.2 RP11-588K22.2 RP11-617D20.1 RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 RPP25 SGOL1 SH2B3 SIK2 SIPA1 SLC2A4 SLC35F6 SLC4A7 SOX6 SRR STAG3L1 STK32C SWAP70 TBC1D19 TCEA2 TCHP TDRD1 TEX15 TH1L TMEM133 TMEM170A TNFRSF25 TNFSF12 TNNT3 TSPY26P TUBB1 UBL7 UCKL1AS UFL1 ULK3 USP37 VEGFB WDR66 WNT3 YEATS4 ZBTB46 ZC3HC1 ZNF318 ZNF641 ZNF652 ZNF831 ZNRF3
Cholesterol lowering medication	3.38	8	6	13.3	0.73	6.6e-03	ABO DCAF16 NTN5 OPRL1 PIGV RGS19 RNF34 VEGFB
Pain experienced in last month	1.54	2	0	0.0	0.00	1.0e+00	KAT8 UFL1
Heart attack/myocardial infarction (self-reported)	2.52	4	1	2.2	0.97	6.9e-03	FES SH2B3 ZC3HC1 ZNF652
Deep venous thrombosis (DVT) (self-reported)	2.95	1	1	2.2	0.00	1.0e+00	ABO
Heart disease (siblings)	1.87	2	0	0.0	0.00	1.0e+00	FES PVRIG
Pack years of smoking	1.27	1	0	0.0	0.00	1.0e+00	PMS2P5
Impedance of whole body	2.23	39	20	44.4	-0.35	2.7e-02	ABCF3 ABO ATG7 CCDC36 CENPW CEP41 CERS5 CISD2 CTB-31O20.6 CTSW DBN1 FAM108C1 FAM57B FLJ12825 HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 LSP1 MSRA MYO9B NEIL2 NOC3L NT5C2 NUCB2 PDE1A PMS2P5 PRKD3 RGS19 RP11-296I10.6 SLC4A7 SRR STAG3L1 SWAP70 TNFSF12 USP37 ZNF641 ZNF652
Leg fat mass (left)	2.15	26	14	31.1	0.83	1.2e-07	AC091133.1 CAST COX5A CTB-31O20.6 CTSW FAM108C1 FAM57B HSD17B12 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MSRA PDE1A PMS2P5 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 STAG3L1 STK32C TDRD1 TEX15 TNFRSF25 TSPY26P
Arm predicted mass (left)	1.90	25	13	28.9	0.30	1.5e-01	ABO C10orf118 CENPW CMIP CTSW DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA NCOA1 NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 STAG3L1 WDR66

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Adipose Subcutaneous	37	1.06	2.9
GTEx	Adipose Visceral Omentum	16	0.79	3.0
GTEx	Adrenal Gland	15	1.03	2.9
GTEx	Artery Aorta	40	1.34	3.1
GTEx	Artery Coronary	10	0.85	2.9
GTEx	Artery Tibial	44	1.17	3.0
GTEx	Brain Caudate basal ganglia	5	0.54	2.9
GTEx	Brain Cerebellar Hemisphere	15	1.01	2.9
GTEx	Brain Cerebellum	19	0.96	3.0
GTEx	Brain Cortex	8	0.77	3.1
GTEx	Brain Frontal Cortex BA9	9	0.97	3.0
GTEx	Brain Hippocampus	2	0.38	2.8
GTEx	Brain Hypothalamus	1	0.17	2.7
GTEx	Brain Nucleus accumbens basal ganglia	5	0.58	2.9
GTEx	Brain Putamen basal ganglia	4	0.64	2.7
GTEx	Breast Mammary Tissue	20	1.01	2.9
GTEx	Breast Mammary Tissue (Male)	14	1.17	2.9
GTEx	Breast Mammary Tissue (Female)	17	1.03	2.9
GTEx	Cells EBV-transformed lymphocytes	8	0.56	2.8
GTEx	Cells Transformed fibroblasts	35	0.83	2.8
GTEx	Colon Sigmoid	17	1.16	2.9
GTEx	Colon Transverse	18	0.87	2.9
GTEx	Esophagus Gastroesophageal Junction	15	1.04	3.0
GTEx	Esophagus Mucosa	32	0.96	2.9
GTEx	Esophagus Muscularis	36	1.11	2.9
GTEx	Heart Atrial Appendage	14	0.89	2.8
GTEx	Heart Left Ventricle	18	1.18	2.9
GTEx	Liver	6	0.84	2.6
GTEx	Lung	26	0.90	3.0
GTEx	Muscle Skeletal	23	0.80	2.9
GTEx	Nerve Tibial	34	0.79	2.8
GTEx	Ovary	11	1.21	3.3
GTEx	Pancreas	15	0.92	2.9
GTEx	Pituitary	11	0.99	2.9
GTEx	Prostate	14	1.68	3.2
GTEx	Skin Not Sun Exposed Suprapubic	28	1.14	3.0
GTEx	Skin Sun Exposed Lower leg	39	1.07	2.9
GTEx	Small Intestine Terminal Ileum	3	0.65	3.0
GTEx	Spleen	11	0.78	2.8
GTEx	Stomach	19	1.31	3.1
GTEx	Testis	31	0.98	2.9
GTEx	Thyroid	41	1.03	2.9
GTEx	Uterus	6	1.06	2.8
GTEx	Vagina	5	0.79	3.0
GTEx	Whole Blood	15	0.75	2.8
METSIM	Adipose	25	0.54	2.5
NTR	Blood	17	0.71	2.7
ROSMAP	Brain Pre-frontal Cortex	54	1.23	3.0
YFS	Blood	28	0.61	2.6
CommonMind	Brain Pre-frontal Cortex	45	0.84	2.7
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	10	0.60	2.6
The Cancer Genome Atlas	Breast Invasive Carcinoma	34	0.77	2.7
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	7	0.64	2.6
The Cancer Genome Atlas	Colon Adenocarcinoma	23	1.11	2.8
The Cancer Genome Atlas	Esophageal Carcinoma	3	0.44	2.6
The Cancer Genome Atlas	Glioblastoma Multiforme	6	0.59	2.6
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	18	0.66	2.6
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	35	0.85	2.8
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	17	0.83	2.7
The Cancer Genome Atlas	Brain Lower Grade Glioma	27	0.63	2.6
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	6	0.54	2.5
The Cancer Genome Atlas	Lung Adenocarcinoma	25	0.85	2.6
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	19	0.76	2.6
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	13	0.82	2.7
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	18	1.08	2.8
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	12	0.90	2.7
The Cancer Genome Atlas	Prostate Adenocarcinoma	28	0.61	2.5
The Cancer Genome Atlas	Rectum Adenocarcinoma	6	0.87	2.7
The Cancer Genome Atlas	Soft Tissue Sarcoma	5	0.47	2.6
The Cancer Genome Atlas	Skin Cutaneous Melanoma	2	0.37	2.7
The Cancer Genome Atlas	Stomach Adenocarcinoma	15	0.89	2.8
The Cancer Genome Atlas	Testicular Germ Cell Tumors	6	0.47	2.6
The Cancer Genome Atlas	Thyroid Carcinoma	39	0.76	2.6
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	4	0.79	2.6