Hub : Traits :

Hypertension (Self-reported)

1359 significantly associated models · 374 unique genes.

Significant Loci

# chr p0 p1 # assoc genes # joint genes best TWAS P best SNP P cond SNP P % var exp joint genes
1 1 5829039 7221458 1 1 1.9e-07 1.2e-06 1.5e-02 75 TNFRSF25
2 1 7715776 9571422 2 1 7.9e-09 1.9e-08 2.3e-01 96 RP5-1115A15.1
3 1 10435170 12600396 8 9 1.7e-28 3.7e-30 NaN NaN CLCN6 MTHFR NPPA NPPA-AS1 RP4-635E18.7
4 1 26428864 28406173 4 2 1.5e-08 2.9e-07 2.6e-01 95 FCN3 PIGV
5 1 88621347 90053563 1 1 1.0e-09 8.8e-10 9.0e-02 92 GTF2B
6 1 112312154 113941737 5 2 5.4e-17 8.5e-22 1.7e-10 56 CAPZA1 RHOC
7 1 230142626 231548480 1 1 3.4e-14 2.4e-12 4.9e-02 92 AGT
8 2 24021231 26068509 4 2 6.6e-12 2.7e-10 2.0e-02 86 EFR3B NCOA1
9 2 26223547 27689899 2 2 5.4e-09 1.4e-34 3.0e-25 28 KCNK3 SLC35F6
10 2 36778887 38298877 2 1 3.6e-10 1.4e-09 1.0e+00 100 PRKD3
11 2 182763586 183632923 1 1 2.3e-07 3.3e-09 1.3e-03 70 PDE1A
12 2 218622292 220128895 1 1 6.1e-08 6.4e-05 6.6e-01 99 USP37
13 3 10617048 12457119 2 1 9.5e-09 9.2e-11 2.6e-03 78 ATG7
14 3 19959756 20466630 1 1 2.0e-07 7.9e-08 1.9e-03 66 SGOL1
15 3 26563909 28211713 2 1 2.2e-16 9.7e-18 9.2e-03 91 SLC4A7
16 3 38812165 40267321 1 1 2.4e-07 7.2e-06 2.2e-03 54 MOBP
17 3 47204518 49538932 9 2 4.5e-12 2.9e-12 1.0e+00 100 CCDC36 FCF1P2
18 3 137189600 138819532 2 1 7.7e-08 4.1e-08 2.2e-01 95 MRAS
19 3 157125828 159106064 3 1 2.9e-09 7.5e-08 3.1e-01 96 RP11-538P18.2
20 3 183204923 184607480 1 1 1.8e-07 6.5e-07 4.2e-01 97 ABCF3
21 4 17104059 18507692 1 1 4.5e-09 1.8e-08 4.1e-03 74 DCAF16
22 4 25880334 27452482 1 2 2.9e-09 2.8e-12 2.4e-07 46 TBC1D19
23 4 37915462 39361551 1 1 1.8e-07 1.9e-08 6.4e-07 22 RP11-617D20.1
24 4 80407869 82578407 3 2 4.8e-20 1.1e-67 2.4e-44 35 C4orf22 PRDM8
25 4 102868793 104627833 5 1 2.3e-11 1.7e-10 8.8e-01 100 CISD2
26 4 110590479 112179424 1 1 7.5e-08 7.3e-13 1.1e-08 37 ENPEP
27 4 155960819 157354250 1 1 1.0e-07 3.0e-12 1.4e-11 6 RP11-588K22.2
28 5 60903201 62529686 2 1 1.4e-07 5.9e-07 7.1e-02 87 IPO11
29 5 95750396 96364645 1 1 3.1e-07 1.9e-06 7.4e-02 86 CAST
30 5 130830617 132425049 8 1 2.8e-08 1.2e-07 2.7e-01 96 PDLIM4
31 5 147516165 148894875 1 1 6.1e-08 3.3e-08 6.2e-05 47 ADRB2
32 5 176043333 177591495 2 1 8.4e-08 1.1e-06 1.0e+00 100 DBN1
33 6 14551209 16209635 1 1 9.3e-08 5.2e-07 1.3e-02 76 JARID2
34 6 42586058 44034691 2 1 4.5e-12 1.7e-12 1.0e+00 100 ZNF318
35 6 78880271 80486611 2 1 1.3e-08 1.6e-08 1.8e-01 94 PHIP
36 6 96275538 97699026 3 1 1.7e-08 5.1e-09 8.3e-02 91 UFL1
37 6 117187910 118613435 1 1 1.9e-07 9.1e-10 8.8e-10 0 GOPC
38 6 125970401 127355237 1 1 2.4e-10 1.7e-30 1.8e-23 24 CENPW
39 7 1854263 3264728 1 1 8.2e-11 1.8e-10 1.0e+00 100 LFNG
40 7 6502367 7988091 1 1 2.1e-14 1.0e-10 1.0e-01 94 C1GALT1
41 7 26969253 27533292 2 1 6.3e-15 7.3e-16 6.3e-03 88 HOXA10
42 7 73425238 75714883 6 2 4.3e-09 9.0e-09 3.4e-01 97 PMS2P5 STAG3L1
43 7 76506844 77966572 1 1 9.1e-08 1.3e-06 1.4e-01 91 PTPN12
44 7 99081730 100516003 2 1 4.1e-08 3.6e-07 6.5e-01 99 PVRIG
45 7 129342404 130779678 2 2 4.9e-09 1.1e-12 2.3e-05 64 CEP41 ZC3HC1
46 7 132241297 134834499 4 2 1.1e-08 2.8e-09 4.5e-01 98 AKR1B1 EXOC4
47 8 8092025 13120332 28 2 1.3e-14 4.2e-13 7.1e-04 78 MSRA NEIL2
48 8 29996824 31433801 1 1 2.0e-08 9.4e-09 1.7e-01 94 TEX15
49 8 90238179 91633434 1 1 2.7e-07 3.6e-08 2.8e-02 84 OSGIN2
50 8 95213858 96825195 2 1 1.1e-08 8.9e-08 4.7e-01 98 NDUFAF6
51 8 102002608 103832256 2 1 4.2e-09 1.3e-09 6.2e-04 68 KB-1107E3.1
52 9 35208145 36597142 1 1 8.9e-09 7.0e-09 1.3e-04 56 HRCT1
53 9 135883620 136399075 1 1 3.0e-08 1.5e-07 4.6e-01 98 ABO
54 10 18221643 19601824 2 2 6.2e-12 6.3e-17 4.9e-12 32 CACNB2 NSUN6
55 10 59577377 61286904 1 1 7.3e-10 3.9e-09 6.8e-02 90 BICC1
56 10 63856856 65606229 3 1 1.1e-11 3.6e-10 2.5e-02 87 NRBF2
57 10 87495534 88960852 2 1 7.4e-08 4.9e-08 3.1e-02 84 LDB3
58 10 95379543 96818402 1 1 1.4e-10 2.9e-13 6.6e-05 70 NOC3L
59 10 103572925 105850787 8 1 7.2e-14 4.5e-15 1.8e-02 91 NT5C2
60 10 115244596 116689519 3 3 3.5e-12 6.3e-19 4.6e-08 62 ADRB1 C10orf118 TDRD1
61 10 133652765 135295396 2 2 1.7e-07 7.0e-08 6.0e-01 99 INPP5A STK32C
62 11 1213806 2705175 5 2 6.8e-22 2.0e-23 6.3e-03 92 LSP1 TNNT3
63 11 9003306 10471931 1 1 1.3e-07 5.1e-10 6.8e-08 25 SWAP70
64 11 15741673 17001235 1 1 2.5e-08 9.8e-16 7.5e-10 41 SOX6
65 11 17037793 17619908 1 1 1.3e-07 6.5e-07 2.6e-02 80 NUCB2
66 11 42881882 44596817 2 1 6.1e-08 3.8e-10 6.5e-04 70 HSD17B12
67 11 46010847 48783497 20 1 6.3e-24 1.2e-19 8.2e-07 70 ACP2
68 11 63305184 64701030 1 1 2.0e-08 7.5e-08 1.0e+00 100 VEGFB
69 11 64721908 66333072 3 2 7.6e-10 3.0e-13 2.2e-02 90 CTSW SIPA1
70 11 99859184 101559718 2 1 2.7e-36 2.5e-35 8.5e-02 98 TMEM133
71 11 106485489 108027561 2 1 1.0e-09 7.6e-10 3.3e-02 88 CWF19L2
72 11 110721187 112491227 6 1 3.0e-11 3.0e-11 1.0e+00 100 SIK2
73 12 47737273 49444545 3 2 8.9e-09 1.1e-08 1.6e-01 94 HDAC7 ZNF641
74 12 49780778 51256065 4 1 4.5e-11 3.7e-12 1.2e-09 23 CERS5
75 12 54158993 54760824 4 1 7.3e-12 1.2e-12 2.8e-03 82 FLJ12825
76 12 69057879 70476863 1 1 1.2e-08 1.8e-06 8.2e-01 100 YEATS4
77 12 89116708 90799212 3 1 9.5e-17 3.9e-25 4.9e-15 43 ATP2B1
78 12 109591369 111015121 2 1 1.1e-08 4.5e-08 8.0e-02 90 TCHP
79 12 111102574 113517494 14 1 3.0e-19 1.6e-27 2.9e-11 62 SH2B3
80 12 121146219 123131824 3 3 2.3e-14 5.6e-14 1.0e+00 100 KDM2B RNF34 WDR66
81 15 40360741 42749023 9 1 1.3e-11 9.8e-12 1.1e-01 94 CHP1
82 15 73933444 76108550 14 9 9.6e-22 2.7e-21 1.0e+00 100 ARID3B COX5A CSK MPI RPP25 UBL7 ULK3
83 15 80377452 81936479 2 1 1.6e-11 1.7e-14 1.6e-04 76 FAM108C1
84 15 90712555 92187978 3 3 6.1e-39 1.5e-28 1.0e+00 100 FES FURIN
85 16 3025993 5441125 5 3 8.2e-10 8.9e-09 6.5e-06 38 AC006111.1 MGRN1
86 16 29711343 31860399 15 2 4.5e-10 5.9e-09 5.3e-01 99 FAM57B KAT8
87 16 53226098 53759123 1 1 1.0e-07 1.3e-06 7.2e-01 99 RBL2
88 16 69337091 71292172 6 1 2.4e-08 1.6e-07 4.5e-01 98 RP11-296I10.6
89 16 74778006 76197034 1 1 2.5e-07 6.2e-06 2.7e-01 94 TMEM170A
90 16 81230341 81993974 1 1 4.1e-13 3.4e-13 5.6e-06 61 CMIP
91 16 89013848 90172696 11 1 2.0e-14 3.8e-14 3.0e-01 98 CHMP1A
92 17 1517914 2918626 1 1 3.0e-07 4.5e-08 1.8e-03 67 SRR
93 17 3208350 4766937 2 1 6.6e-10 3.7e-09 3.8e-01 98 RP11-810M2.2
94 17 6493198 8484683 10 3 6.3e-13 6.3e-13 1.0e+00 100 CYB5D1 SLC2A4 TNFSF12
95 17 42976114 43383100 1 1 5.6e-08 7.9e-07 4.6e-02 84 HEXIM1
96 17 44788310 45597098 1 1 1.9e-07 1.4e-11 2.1e-11 2 WNT3
97 17 46258510 47718188 7 2 2.3e-11 2.7e-14 2.6e-04 77 AC091133.1 ZNF652
98 17 60858059 62279811 2 1 9.4e-16 9.4e-16 1.0e+00 100 ACE
99 17 73175294 74629867 4 1 1.2e-08 8.5e-09 2.6e-01 96 FBF1
100 17 78665405 80023050 1 1 2.1e-07 8.0e-06 1.9e-04 30 RP11-1055B8.4
101 19 1163934 2560423 3 2 7.4e-10 4.3e-09 1.0e+00 100 CTB-31O20.6 KLF16
102 19 16045294 18007950 4 1 1.7e-12 5.8e-14 5.8e-05 71 MYO9B
103 19 48464978 49935001 4 1 2.7e-09 1.5e-08 4.0e-01 98 NTN5
104 20 7419920 9648826 1 2 2.1e-11 9.1e-19 4.7e-06 73 PLCB1
105 20 29927166 31469577 2 2 1.1e-08 7.6e-07 4.2e-05 31 C20orf160 TSPY26P
106 20 56858751 58262841 4 7 4.3e-18 2.5e-34 NaN NaN NELFCD TH1L TUBB1 ZNF831
107 20 61522825 62912463 8 10 2.2e-12 4.6e-12 1.0e+00 100 GMEB2 OPRL1 RGS19 TCEA2 UCKL1AS ZBTB46
108 21 44512286 45879403 2 1 2.3e-07 5.2e-08 1.7e-07 8 PDXK
109 22 28943477 29807855 3 1 4.1e-12 1.2e-08 2.9e-05 46 ZNRF3

Pleiotropic Associations

Trait chisq ratio # genes+ # genes++ % genes++ corr corr P genes
Bipolar Disorder (2018) 1.88 1 0 0.0 0.00 1.0e+00 ZC3HC1
Bipolar Disorder or Schizophrenia 1.96 7 4 8.9 -0.46 2.5e-01 CERS5 CHMP1A FAM57B FES FURIN NT5C2 TBC1D19
Depressed Affect (Nagel 2018) 1.25 5 3 6.7 -0.51 3.8e-01 ACP2 OSGIN2 RP5-1115A15.1 SH2B3 WNT3
Depression (Nagel 2018) 1.23 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Intelligence (Savage-Jansen 2018) 1.21 3 2 4.4 0.00 1.0e+00 DCAF16 GTF2B RBL2
Neuroticism (Nagel 2018) 1.16 5 2 4.4 -0.41 4.9e-01 ACP2 FURIN KAT8 RP5-1115A15.1 WNT3
Schizophrenia (2018) 1.81 4 3 6.7 -0.78 1.2e-01 FAM57B FES FURIN NT5C2
Worry (Nagel 2018) 1.27 2 2 4.4 0.00 1.0e+00 KAT8 NT5C2
Alzheimer’s Disease (including proxy) 1.44 4 2 4.4 -0.99 7.4e-03 ACE KAT8 PRKD3 PVRIG
Crohns Disease (2017) 1.41 3 2 4.4 0.00 1.0e+00 NTN5 PDLIM4 PMS2P5
Irritable Bowel Disease (IBD) 1.50 5 1 2.2 -0.82 8.9e-02 GMEB2 OPRL1 PDLIM4 PMS2P5 RGS19
Ulcerative Colitis (UC) 1.48 2 0 0.0 -0.29 6.4e-01 OPRL1 RGS19
Major Depression (MDD) 1.16 1 0 0.0 0.00 1.0e+00 FES
Reaction Time 1.12 1 1 2.2 0.00 1.0e+00 SH2B3
Verbal and Numeric Reasoning (VNR) 1.15 3 2 4.4 0.00 1.0e+00 DCAF16 RBL2 TEX15
Breast Cancer 2.25 12 3 6.7 0.50 5.9e-02 CSK FES FURIN LSP1 OPRL1 PDLIM4 PMS2P5 RGS19 RP11-1055B8.4 SIK2 SLC4A7 UBL7
Ovarian Cancer 1.27 2 0 0.0 0.00 1.0e+00 ABO WNT3
Prostate Cancer 1.36 1 0 0.0 0.00 1.0e+00 TNNT3
Body Mass Index (BMI) (2010) 1.77 1 0 0.0 0.00 1.0e+00 STAG3L1
Coronary Artery Disease (CAD) 2.07 2 2 4.4 0.00 1.0e+00 ABO MRAS
Crohns Disease (2012) 1.25 1 1 2.2 0.00 1.0e+00 PDLIM4
Fasting Glucose 1.63 1 1 2.2 0.00 1.0e+00 ACP2
HDL Cholesterol 1.44 4 1 2.2 -0.70 3.0e-01 ACP2 ADRB1 CTSW PIGV
LDL Cholesterol 1.81 4 1 2.2 -0.28 7.2e-01 ABO NTN5 PIGV SH2B3
Neuroticism (2016) 1.25 2 0 0.0 0.00 1.0e+00 MSRA NEIL2
Primary Biliary Cirrhosis 1.23 2 1 2.2 0.00 1.0e+00 CISD2 SH2B3
Rheumatoid Arthritis 1.31 2 0 0.0 0.00 1.0e+00 RGS19 SH2B3
Schizophrenia (2014) 1.78 6 3 6.7 -0.36 4.3e-01 CERS5 FAM57B FES FURIN NT5C2 RP5-1115A15.1
Triglycerides 1.45 3 0 0.0 0.00 1.0e+00 KAT8 NEIL2 NRBF2
Blood Eosinophil Count 3.57 23 17 37.8 0.59 2.9e-03 ABO ADRB2 CCDC36 CERS5 FAM57B FBF1 KAT8 NDUFAF6 NUCB2 PDLIM4 PDXK PIGV RP11-617D20.1 RP5-1115A15.1 SH2B3 SIK2 SIPA1 TCHP TSPY26P WNT3 ZC3HC1 ZNF652 ZNF831
Blood Platelet Count 2.91 43 34 75.6 -0.25 8.7e-02 ABCF3 AC091133.1 C20orf160 CAPZA1 CAST CERS5 CLCN6 COX5A CSK CTSW CWF19L2 DCAF16 FBF1 GMEB2 GTF2B HDAC7 HEXIM1 LFNG MGRN1 MPI MTHFR MYO9B NELFCD NRBF2 NTN5 NUCB2 PDLIM4 PHIP PIGV RHOC RP11-617D20.1 RPP25 SH2B3 SIK2 SLC4A7 SWAP70 TH1L TMEM170A TUBB1 UBL7 USP37 ZC3HC1 ZNF318
Blood Red Count 1.91 44 26 57.8 0.24 8.8e-02 ABO ARID3B BICC1 C20orf160 C4orf22 CENPW CHMP1A CLCN6 COX5A CSK CYB5D1 FAM57B FBF1 GMEB2 GTF2B HEXIM1 INPP5A IPO11 KAT8 MGRN1 MPI MTHFR NCOA1 NDUFAF6 NELFCD NPPA NPPA-AS1 NT5C2 PDXK PVRIG RP11-617D20.1 RPP25 SH2B3 SLC35F6 TDRD1 TH1L TSPY26P TUBB1 UBL7 ULK3 USP37 VEGFB WNT3 ZNF641
Blood White Count 1.93 30 14 31.1 0.57 7.3e-04 ABO ADRB2 C10orf118 CERS5 CMIP CYB5D1 DCAF16 FBF1 FES FLJ12825 FURIN GTF2B KB-1107E3.1 KCNK3 MGRN1 MOBP NRBF2 NT5C2 PDLIM4 PLCB1 RP11-617D20.1 RP5-1115A15.1 SGOL1 SH2B3 SRR TEX15 TMEM133 ULK3 VEGFB ZNF652
Heel T-Score 1.89 36 28 62.2 -0.13 4.4e-01 ABO ACP2 ATG7 BICC1 C20orf160 CAPZA1 CCDC36 CMIP CTSW CYB5D1 DCAF16 FAM57B GTF2B HEXIM1 INPP5A KAT8 LFNG NCOA1 NELFCD NT5C2 PMS2P5 RHOC RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 SIPA1 SOX6 STK32C TH1L TMEM133 TNFRSF25 TNFSF12 TUBB1 WNT3 ZNF318 ZNRF3
BMI 2.21 40 24 53.3 0.57 1.1e-04 AC006111.1 AC091133.1 C20orf160 C4orf22 CAST CEP41 CHP1 CISD2 CLCN6 COX5A CTB-31O20.6 CTSW FAM108C1 FAM57B FBF1 HSD17B12 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MRAS NRBF2 NT5C2 PDE1A PMS2P5 RGS19 RNF34 RP11-296I10.6 RP11-538P18.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25 TSPY26P USP37
Height 1.71 53 43 95.6 -0.34 1.4e-02 ABO AC006111.1 AC091133.1 ACE ACP2 ADRB1 ARID3B BICC1 CAPZA1 CENPW CERS5 CHP1 CTSW DBN1 DCAF16 EFR3B FAM57B FES FURIN GOPC GTF2B HEXIM1 HRCT1 LSP1 MGRN1 NCOA1 NT5C2 NTN5 NUCB2 PDLIM4 PIGV PTPN12 RBL2 RHOC RP11-1055B8.4 RP11-538P18.2 RP11-617D20.1 RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 SH2B3 SLC35F6 SLC4A7 STAG3L1 TMEM133 TMEM170A ULK3 USP37 WDR66 YEATS4 ZNF318 ZNF652 ZNF831
Waist Hip Ratio (WHR) 2.20 23 14 31.1 0.61 7.6e-04 CEP41 CMIP CTSW DBN1 FLJ12825 GTF2B MRAS MYO9B NCOA1 NTN5 OPRL1 PTPN12 RBL2 RGS19 SIK2 SIPA1 SWAP70 TBC1D19 TCEA2 VEGFB WNT3 ZNF318 ZNRF3
Systolic Blood Pressure 13.21 124 105 233.3 0.96 9.3e-82 ABCF3 AC006111.1 AC091133.1 ACE ACP2 ADRB1 ADRB2 AGT AKR1B1 ARID3B ATG7 ATP2B1 BICC1 C10orf118 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CCDC36 CENPW CERS5 CHP1 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTSW CWF19L2 CYB5D1 DCAF16 EFR3B ENPEP FAM108C1 FBF1 FCF1P2 FCN3 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HDAC7 HEXIM1 HOXA10 HRCT1 IPO11 KB-1107E3.1 KDM2B KLF16 LDB3 LFNG LSP1 MGRN1 MPI MRAS MTHFR MYO9B NCOA1 NDUFAF6 NEIL2 NELFCD NOC3L NPPA NPPA-AS1 NRBF2 NSUN6 NT5C2 NTN5 NUCB2 OPRL1 PDE1A PDXK PHIP PIGV PLCB1 PRDM8 PRKD3 PTPN12 RGS19 RHOC RNF34 RP11-1055B8.4 RP11-296I10.6 RP11-538P18.2 RP11-588K22.2 RP4-635E18.7 RP5-1115A15.1 RPP25 SH2B3 SIK2 SIPA1 SLC2A4 SLC4A7 SOX6 SRR STAG3L1 SWAP70 TBC1D19 TCEA2 TCHP TH1L TMEM133 TMEM170A TNFRSF25 TNFSF12 TNNT3 TUBB1 UBL7 UCKL1AS UFL1 ULK3 VEGFB WDR66 WNT3 ZBTB46 ZC3HC1 ZNF318 ZNF641 ZNF652 ZNF831 ZNRF3
Smoking Status 1.30 6 0 0.0 -0.16 7.3e-01 CTSW FAM108C1 FES RP5-1115A15.1 SRR ZNF652
Allergy or Eczema 2.06 13 5 11.1 0.26 4.0e-01 ABO CHP1 CLCN6 GMEB2 HDAC7 HEXIM1 NRBF2 PDLIM4 RNF34 RP5-1115A15.1 SIK2 SRR ZNF652
Cardiovascular Disease 13.49 142 117 260.0 0.99 4.0e-134 ABCF3 AC006111.1 AC091133.1 ACE ACP2 ADRB1 ADRB2 AGT AKR1B1 ARID3B ATG7 ATP2B1 BICC1 C10orf118 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CAST CCDC36 CENPW CEP41 CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTSW CWF19L2 CYB5D1 DBN1 DCAF16 EFR3B ENPEP EXOC4 FAM108C1 FAM57B FBF1 FCF1P2 FCN3 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HEXIM1 HOXA10 HRCT1 HSD17B12 IPO11 JARID2 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 LDB3 LFNG LSP1 MGRN1 MOBP MPI MRAS MTHFR MYO9B NCOA1 NDUFAF6 NELFCD NOC3L NPPA NPPA-AS1 NRBF2 NSUN6 NT5C2 NTN5 NUCB2 OPRL1 PDE1A PDXK PHIP PIGV PLCB1 PMS2P5 PRDM8 PTPN12 PVRIG RBL2 RGS19 RHOC RNF34 RP11-1055B8.4 RP11-296I10.6 RP11-538P18.2 RP11-588K22.2 RP11-617D20.1 RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 RPP25 SH2B3 SIK2 SIPA1 SLC2A4 SLC35F6 SLC4A7 SOX6 STAG3L1 SWAP70 TBC1D19 TCEA2 TCHP TDRD1 TEX15 TH1L TMEM133 TMEM170A TNFRSF25 TNFSF12 TNNT3 TSPY26P TUBB1 UBL7 UCKL1AS UFL1 ULK3 USP37 VEGFB WDR66 YEATS4 ZBTB46 ZC3HC1 ZNF318 ZNF641 ZNF652 ZNF831 ZNRF3
Hypothyroidism (self reported) 1.82 3 1 2.2 0.00 1.0e+00 NTN5 RP5-1115A15.1 SH2B3
Respiratory disease 1.73 9 3 6.7 0.58 1.0e-01 CHP1 FBF1 GMEB2 HDAC7 HEXIM1 PDLIM4 RP5-1115A15.1 SIK2 ZNF652
Type 2 Diabetes (T2D) (2018) 2.12 9 2 4.4 0.97 1.6e-05 ACE CTSW MRAS NDUFAF6 PMS2P5 RBL2 SH2B3 VEGFB ZBTB46
Lung FEV1/FVC ratio 1.84 27 15 33.3 -0.36 6.2e-02 ABO ATG7 ATP2B1 C1GALT1 CACNB2 CENPW CEP41 CTB-31O20.6 CYB5D1 FLJ12825 GOPC HDAC7 INPP5A KB-1107E3.1 NRBF2 NTN5 PDLIM4 PVRIG RP11-810M2.2 RP5-1115A15.1 STK32C TMEM133 TMEM170A TNFRSF25 TSPY26P WNT3 ZNF652
Lung FVC 1.68 17 11 24.4 -0.25 2.9e-01 C1GALT1 CHP1 DCAF16 FLJ12825 GMEB2 HOXA10 HSD17B12 KAT8 NCOA1 NRBF2 OPRL1 PDLIM4 RGS19 RP11-538P18.2 TNFRSF25 WNT3 ZBTB46
Neuroticism 1.15 4 2 4.4 -0.46 5.4e-01 FURIN NT5C2 RP5-1115A15.1 WNT3
Chronotype (morning person) 1.08 2 0 0.0 0.00 1.0e+00 RP11-810M2.2 RP5-1115A15.1
Hair Pigment 0.91 17 10 22.2 0.25 3.0e-01 ACP2 ATP2B1 C20orf160 C4orf22 CHMP1A CTSW FES OPRL1 PIGV RGS19 SH2B3 SIPA1 SOX6 TSPY26P WNT3 ZNF831 ZNRF3
Tanning 1.37 6 3 6.7 -0.28 5.9e-01 CHMP1A DBN1 NRBF2 SH2B3 TSPY26P UBL7
Hand grip strength (left) 1.44 6 2 4.4 -0.64 1.7e-01 DCAF16 FAM57B FES HEXIM1 MGRN1 PDLIM4
Number of treatments/medications taken 4.11 15 6 13.3 0.94 1.6e-07 AC091133.1 ACE CHP1 CISD2 DCAF16 FAM108C1 FES RP11-617D20.1 SH2B3 STK32C TMEM133 YEATS4 ZNF652 ZNF831 ZNRF3
Sensitivity / hurt feelings 1.38 4 3 6.7 -0.64 2.4e-01 AC091133.1 FES FURIN WNT3
Frequency of depressed mood in last 2 weeks 1.23 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Hearing difficulty/problems: Yes 1.03 1 1 2.2 0.00 1.0e+00 ZNF318
Relative age of first facial hair 1.28 5 3 6.7 -0.74 1.6e-01 ATG7 C4orf22 HEXIM1 SIPA1 WNT3
Systolic blood pressure, automated reading 10.01 90 58 128.9 0.98 7.1e-66 AC006111.1 ACP2 ADRB1 ADRB2 AGT ATG7 ATP2B1 BICC1 C4orf22 CACNB2 CAPZA1 CCDC36 CERS5 CHP1 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTSW CWF19L2 DCAF16 FAM108C1 FAM57B FCF1P2 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HDAC7 HEXIM1 HOXA10 INPP5A IPO11 KLF16 LFNG LSP1 MGRN1 MPI MSRA MTHFR MYO9B NCOA1 NEIL2 NOC3L NPPA NPPA-AS1 NRBF2 NSUN6 NT5C2 NUCB2 OPRL1 PDE1A PHIP PIGV PMS2P5 PRKD3 RGS19 RHOC RP11-296I10.6 RP11-538P18.2 RP11-588K22.2 RP4-635E18.7 RP5-1115A15.1 RPP25 SH2B3 SLC2A4 SLC4A7 SOX6 SRR STAG3L1 SWAP70 TBC1D19 TCEA2 TCHP TH1L TMEM133 TMEM170A TNFSF12 TNNT3 UBL7 UFL1 ULK3 WNT3 ZBTB46 ZNF318 ZNF831 ZNRF3
Angina 2.93 5 3 6.7 0.96 6.6e-04 FES FURIN OPRL1 RGS19 ZNF652
Medication: Metformin 1.75 2 0 0.0 0.00 1.0e+00 CISD2 PMS2P5
Diabetes (father) 1.13 1 0 0.0 0.00 1.0e+00 AC091133.1
Pack years adult smoking proportion 1.31 1 0 0.0 0.00 1.0e+00 PMS2P5
Impedance of leg (right) 2.30 40 20 44.4 -0.03 8.7e-01 ABCF3 AC091133.1 ATG7 CEP41 CERS5 CTB-31O20.6 CTSW DBN1 FAM108C1 FAM57B FES FLJ12825 FURIN HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA MYO9B NEIL2 NELFCD NOC3L NT5C2 NUCB2 PDE1A PMS2P5 PRKD3 RBL2 RGS19 SLC35F6 SRR STAG3L1 SWAP70 TH1L TMEM133 USP37 WDR66 ZNF641 ZNF652
Leg fat-free mass (left) 1.92 27 15 33.3 0.19 3.5e-01 ABCF3 C10orf118 CENPW CTB-31O20.6 CTSW DBN1 DCAF16 FAM108C1 FAM57B FES FURIN HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SLC35F6 SRR STAG3L1 TDRD1 WDR66
Trunk fat percentage 1.99 27 11 24.4 0.67 1.5e-04 ABO AC091133.1 CHP1 CTB-31O20.6 CTSW FAM108C1 FAM57B FLJ12825 HOXA10 HSD17B12 KAT8 KCNK3 KDM2B MRAS MYO9B NOC3L RNF34 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 SRR STAG3L1 STK32C TEX15 TNFRSF25 TNFSF12 WNT3
Hand grip strength (right) 1.58 8 3 6.7 -0.66 7.4e-02 ABO CAPZA1 DCAF16 HEXIM1 JARID2 PDLIM4 RHOC UCKL1AS
Townsend deprivation index at recruitment 1.17 1 0 0.0 0.00 1.0e+00 KLF16
Current tobacco smoking 1.62 1 0 0.0 0.00 1.0e+00 MSRA
Maternal smoking around birth 1.19 1 0 0.0 0.00 1.0e+00 C20orf160
Fed-up feelings 1.25 3 1 2.2 0.00 1.0e+00 SH2B3 SLC2A4 TEX15
Relative age voice broke 1.14 1 0 0.0 0.00 1.0e+00 WNT3
Taking other prescription medications 2.04 4 2 4.4 1.00 1.8e-03 CISD2 PMS2P5 SH2B3 ZNF652
Age when periods started (menarche) 1.67 9 4 8.9 -0.05 9.0e-01 CCDC36 CTB-31O20.6 CTSW FAM57B HSD17B12 KLF16 NTN5 PMS2P5 STAG3L1
Heel bone mineral density (BMD) T-score, automated (left) 1.67 8 4 8.9 -0.21 6.2e-01 ACP2 CMIP CYB5D1 MSRA NEIL2 RP5-1115A15.1 SIPA1 ZNRF3
High blood pressure 14.82 154 139 308.9 1.00 1.0e-234 ABCF3 ABO AC006111.1 AC091133.1 ACE ACP2 ADRB1 ADRB2 AGT AKR1B1 ARID3B ATG7 ATP2B1 BICC1 C10orf118 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CAST CCDC36 CENPW CEP41 CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTSW CWF19L2 CYB5D1 DBN1 DCAF16 EFR3B ENPEP EXOC4 FAM108C1 FAM57B FBF1 FCF1P2 FCN3 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HDAC7 HEXIM1 HOXA10 HRCT1 HSD17B12 INPP5A IPO11 JARID2 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 LDB3 LFNG LSP1 MGRN1 MOBP MPI MRAS MSRA MTHFR MYO9B NCOA1 NDUFAF6 NEIL2 NELFCD NOC3L NPPA NPPA-AS1 NRBF2 NSUN6 NT5C2 NTN5 NUCB2 OPRL1 OSGIN2 PDE1A PDLIM4 PDXK PHIP PIGV PLCB1 PMS2P5 PRDM8 PRKD3 PTPN12 PVRIG RBL2 RGS19 RHOC RNF34 RP11-1055B8.4 RP11-296I10.6 RP11-538P18.2 RP11-588K22.2 RP11-617D20.1 RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 RPP25 SGOL1 SH2B3 SIK2 SIPA1 SLC2A4 SLC35F6 SLC4A7 SOX6 SRR STAG3L1 STK32C SWAP70 TBC1D19 TCEA2 TCHP TDRD1 TEX15 TH1L TMEM133 TMEM170A TNFRSF25 TNFSF12 TNNT3 TSPY26P TUBB1 UBL7 UCKL1AS UFL1 ULK3 USP37 VEGFB WDR66 WNT3 YEATS4 ZBTB46 ZC3HC1 ZNF318 ZNF641 ZNF652 ZNF831 ZNRF3
Hayfever, allergic rhinitis or eczema 1.96 5 5 11.1 0.57 3.1e-01 CHP1 PDLIM4 RP5-1115A15.1 SIK2 ZNF652
Supplements: Glucosamine 1.59 2 1 2.2 0.00 1.0e+00 CSK NRBF2
Medication: Atenolol 5.41 7 2 4.4 0.99 4.3e-06 CLCN6 FES FURIN PRKD3 RHOC SH2B3 TMEM133
Medication: Levothyroxine sodium 1.68 2 1 2.2 0.00 1.0e+00 MSRA SH2B3
Sitting height 1.44 25 14 31.1 -0.17 4.1e-01 AC091133.1 ADRB1 C10orf118 C20orf160 CENPW CERS5 CHP1 DCAF16 FCN3 GOPC GTF2B HEXIM1 JARID2 NTN5 PDLIM4 RBL2 RP11-538P18.2 SLC35F6 SLC4A7 WDR66 WNT3 ZNF641 ZNF652 ZNF831 ZNRF3
High blood pressure (mother) 5.55 14 4 8.9 0.96 4.3e-10 AGT CENPW CHMP1A CLCN6 FES FLJ12825 FURIN HOXA10 LSP1 NT5C2 PIGV SLC4A7 TNFRSF25 ZNF831
Body mass index (BMI) 2.35 30 18 40.0 0.78 2.9e-07 AC091133.1 CAST CEP41 COX5A CTB-31O20.6 CTSW DCAF16 FAM108C1 FAM57B HSD17B12 KAT8 KCNK3 KDM2B KLF16 MSRA NEIL2 NRBF2 NT5C2 PDE1A PMS2P5 RP11-296I10.6 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25 USP37
Impedance of leg (left) 2.31 37 22 48.9 -0.07 6.5e-01 ABCF3 AC091133.1 ATG7 CEP41 CERS5 CTB-31O20.6 CTSW DBN1 FAM108C1 FAM57B FES FLJ12825 FURIN HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA MYO9B NEIL2 NELFCD NOC3L NT5C2 NUCB2 PMS2P5 PRKD3 RBL2 RGS19 RP11-296I10.6 SLC35F6 SRR STAG3L1 SWAP70 TMEM133 USP37 ZNF652
Leg predicted mass (left) 1.92 27 15 33.3 0.15 4.7e-01 ABCF3 C10orf118 CENPW CTSW DBN1 DCAF16 FAM108C1 FAM57B FES FURIN HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA MYO9B NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SLC35F6 SRR STAG3L1 TDRD1 WDR66
Trunk fat mass 1.96 24 9 20.0 0.65 5.7e-04 CAST CTB-31O20.6 CTSW FAM108C1 FAM57B HOXA10 HSD17B12 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MRAS NT5C2 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25
Waist circumference 2.26 26 12 26.7 0.70 6.3e-05 CMIP COX5A CTB-31O20.6 CTSW EFR3B EXOC4 FAM108C1 FAM57B HSD17B12 KAT8 KB-1107E3.1 KCNK3 KLF16 MPI NRBF2 PHIP RP11-296I10.6 RP11-810M2.2 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25 UBL7
Number of incorrect matches in round 1.41 4 1 2.2 -1.00 2.6e-06 FAM57B FES FURIN KAT8
Past tobacco smoking 1.26 1 0 0.0 0.00 1.0e+00 SH2B3
Alcohol usually taken with meals 1.23 1 0 0.0 0.00 1.0e+00 FES
Nervous feelings 1.32 3 1 2.2 0.00 1.0e+00 KAT8 MSRA NT5C2
Frequency of tenseness / restlessness in last 2 weeks 1.14 1 0 0.0 0.00 1.0e+00 NT5C2
Hearing difficulty/problems with background noise 1.52 4 2 4.4 -0.99 8.3e-03 CSK UBL7 ULK3 ZNF318
Hair/balding pattern: Pattern 2 1.51 2 1 2.2 0.00 1.0e+00 C4orf22 PRDM8
Had menopause 1.04 1 0 0.0 0.00 1.0e+00 CHP1
Forced vital capacity (FVC) 1.71 11 6 13.3 -0.36 2.8e-01 CAPZA1 CENPW DCAF16 GMEB2 KAT8 NCOA1 RBL2 RHOC RP11-538P18.2 WDR66 WNT3
Heel bone mineral density (BMD) T-score, automated (right) 1.65 7 5 11.1 -0.17 7.2e-01 ACP2 CYB5D1 MSRA NEIL2 RP5-1115A15.1 SIPA1 ZNRF3
Qualifications: None of the above 1.35 2 1 2.2 0.00 1.0e+00 PHIP RBL2
Mouth/teeth dental problems 1.41 2 0 0.0 0.00 1.0e+00 NTN5 PMS2P5
Heart attack 2.53 3 1 2.2 0.00 1.0e+00 FES ZC3HC1 ZNF652
Allergy 2.22 10 6 13.3 -0.19 6.1e-01 ABO CHP1 FES GMEB2 HDAC7 HEXIM1 PDLIM4 RP5-1115A15.1 SIK2 ZNF652
Diabetes (self-reported) 1.94 3 1 2.2 0.00 1.0e+00 PMS2P5 RBL2 ZBTB46
Medication: Ramipril 4.77 8 2 4.4 0.98 2.9e-05 CISD2 CMIP CSK FES GOPC LSP1 TMEM133 ZC3HC1
Medication: Simvastatin 4.22 10 4 8.9 0.76 1.5e-03 ABO DCAF16 FES NTN5 OPRL1 PIGV RGS19 VEGFB YEATS4 ZNF831
Fluid intelligence score 1.17 2 2 4.4 0.00 1.0e+00 DCAF16 RBL2
Illnesses of siblings 3.88 7 2 4.4 -0.98 1.4e-06 CLCN6 FES KAT8 NRBF2 RBL2 SH2B3 TMEM133
Neuroticism score 1.18 4 3 6.7 -0.99 1.1e-02 MSRA NEIL2 RP5-1115A15.1 WNT3
Weight 2.00 30 16 35.6 0.44 1.5e-02 C10orf118 CAST CTB-31O20.6 CTSW DCAF16 EFR3B EXOC4 FAM108C1 FAM57B HSD17B12 KAT8 KB-1107E3.1 KCNK3 KLF16 MRAS MSRA NEIL2 NT5C2 PDE1A PDLIM4 RBL2 RP11-296I10.6 RP11-810M2.2 RPP25 SH2B3 SRR STAG3L1 STK32C TDRD1 WDR66
Impedance of arm (right) 2.05 31 14 31.1 -0.45 1.1e-02 ABO ARID3B CCDC36 CERS5 CISD2 CMIP CTB-31O20.6 CTSW FAM57B FLJ12825 HEXIM1 HOXA10 HSD17B12 KAT8 KLF16 LSP1 MSRA MYO9B NEIL2 NOC3L NRBF2 NUCB2 PDE1A RGS19 SLC4A7 STAG3L1 TNFSF12 TSPY26P UCKL1AS ZNF641 ZNF652
Arm fat percentage (right) 2.20 30 17 37.8 0.66 7.8e-05 ABO AC091133.1 CHP1 COX5A CTB-31O20.6 CTSW DCAF16 FAM108C1 FAM57B FBF1 HOXA10 HSD17B12 KAT8 KCNK3 KDM2B KLF16 MSRA NT5C2 PMS2P5 RNF34 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 SLC2A4 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25
Trunk fat-free mass 1.86 25 18 40.0 0.01 9.5e-01 ABO C10orf118 CENPW DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 JARID2 KAT8 KCNK3 KLF16 MYO9B NCOA1 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 SLC4A7 TMEM133 WDR66
Hip circumference 2.14 29 12 26.7 0.17 3.6e-01 CAST CLCN6 CTB-31O20.6 FAM108C1 FAM57B FBF1 HSD17B12 KAT8 KB-1107E3.1 KCNK3 KLF16 MRAS MSRA NPPA NPPA-AS1 NT5C2 PDE1A PHIP PMS2P5 RBL2 RGS19 RP11-296I10.6 RP11-810M2.2 SH2B3 SRR STAG3L1 STK32C VEGFB WDR66
Alcohol intake versus 10 years previously 1.15 2 0 0.0 0.00 1.0e+00 FAM57B NTN5
Father's age at death 2.27 3 2 4.4 0.00 1.0e+00 ABO FES SH2B3
Worrier / anxious feelings 1.51 4 1 2.2 -0.59 4.1e-01 KAT8 MSRA NEIL2 NT5C2
Frequency of tiredness / lethargy in last 2 weeks 1.37 3 1 2.2 0.00 1.0e+00 AC091133.1 CCDC36 RP5-1115A15.1
Hair/balding pattern: Pattern 3 1.76 4 2 4.4 0.71 2.9e-01 C4orf22 HEXIM1 PRDM8 WNT3
Forced expiratory volume in 1-second (FEV1) 1.77 13 3 6.7 -0.30 3.1e-01 ABO DCAF16 GOPC KAT8 MSRA NCOA1 NRBF2 PDLIM4 RHOC RP11-538P18.2 TMEM133 TSPY26P WNT3
Pulse rate 1.03 1 0 0.0 0.00 1.0e+00 RBL2
Qualifications: A levels/AS levels or equivalent 1.25 2 0 0.0 0.00 1.0e+00 RBL2 STAG3L1
Serious illness, injury or assault of a close relative in last 2 years 1.17 1 0 0.0 0.00 1.0e+00 NTN5
Mouth/teeth dental problems: Dentures 1.22 2 1 2.2 0.00 1.0e+00 NTN5 RP11-1055B8.4
Asthma 1.89 5 4 8.9 0.63 2.6e-01 HDAC7 PDLIM4 RP5-1115A15.1 SIK2 ZNF652
Medication: Cholesterol lowering 4.20 13 5 11.1 0.85 1.6e-05 ABO CHP1 CLCN6 FES NTN5 OPRL1 PIGV PVRIG RGS19 TMEM133 TNFRSF25 YEATS4 ZNF831
Depression (self-reported) 1.05 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Illnesses of mother 3.65 1 1 2.2 0.00 1.0e+00 FES
Forced expiratory volume in 1-second (FEV1), Best measure 1.69 9 5 11.1 -0.24 5.3e-01 ABO DCAF16 KAT8 NCOA1 NRBF2 PDLIM4 RP11-538P18.2 TMEM133 WNT3
Pulse wave Arterial Stiffness index 1.84 1 0 0.0 0.00 1.0e+00 VEGFB
Impedance of arm (left) 2.09 31 17 37.8 -0.39 3.2e-02 ABO ARID3B CCDC36 CERS5 CISD2 CMIP CTSW FAM108C1 FAM57B FLJ12825 HEXIM1 HOXA10 HSD17B12 KAT8 LSP1 MSRA MYO9B NEIL2 NOC3L NRBF2 PDE1A PRKD3 RGS19 SH2B3 SLC4A7 STAG3L1 TNFSF12 TSPY26P UCKL1AS ZNF641 ZNF652
Arm fat mass (right) 2.19 28 13 28.9 0.69 4.1e-05 AC091133.1 CAST COX5A CTB-31O20.6 CTSW EFR3B FAM108C1 FAM57B HOXA10 HSD17B12 KAT8 KCNK3 KDM2B KLF16 MSRA NT5C2 PDE1A PMS2P5 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25
Trunk predicted mass 1.86 24 17 37.8 0.05 8.3e-01 ABO C10orf118 CENPW DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 JARID2 KAT8 KCNK3 KLF16 MYO9B NCOA1 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 SLC4A7 WDR66
Standing height 1.66 42 25 55.6 -0.29 6.3e-02 AC006111.1 AC091133.1 ACP2 ADRB1 C10orf118 CAPZA1 CENPW CERS5 CHP1 DBN1 DCAF16 EFR3B FAM57B GOPC GTF2B HEXIM1 LSP1 MGRN1 MSRA NCOA1 NUCB2 PDLIM4 PIGV PTPN12 RBL2 RHOC RP11-1055B8.4 RP11-538P18.2 RP11-617D20.1 RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 SH2B3 SLC35F6 SLC4A7 TMEM170A ULK3 USP37 WDR66 ZNF318 ZNF652 ZNF831
Tense / 'highly strung' 1.10 3 0 0.0 0.00 1.0e+00 KAT8 NT5C2 RP5-1115A15.1
Hair/balding pattern: Pattern 4 2.04 8 6 13.3 0.49 2.2e-01 C4orf22 CENPW CERS5 HEXIM1 PRDM8 RP5-1115A15.1 SRR WNT3
Birth weight of first child 3.32 15 4 8.9 -0.98 1.9e-13 CLCN6 COX5A CSK DCAF16 FES FURIN GTF2B MTHFR NPPA-AS1 OPRL1 RGS19 RPP25 SH2B3 STAG3L1 TMEM170A
Peak expiratory flow (PEF) 1.71 8 4 8.9 -0.61 1.1e-01 ABO C1GALT1 DCAF16 MSRA NTN5 SLC2A4 TMEM170A WNT3
Pulse wave reflection index 1.30 2 0 0.0 0.00 1.0e+00 FLJ12825 INPP5A
Blood clot in the leg (DVT) 2.96 1 1 2.2 0.00 1.0e+00 ABO
Medication: Paracetamol 1.67 1 0 0.0 0.00 1.0e+00 UFL1
Headache pain in last month 1.51 3 1 2.2 0.00 1.0e+00 TMEM170A UFL1 WNT3
Medication for cholesterol, blood pressure or diabetes 8.17 37 14 31.1 -0.98 5.4e-33 ACE ATP2B1 C1GALT1 C4orf22 CHP1 CISD2 CLCN6 CSK CTSW FAM108C1 FCF1P2 FES FURIN JARID2 LFNG MTHFR OPRL1 OSGIN2 PDXK PLCB1 PVRIG RGS19 RHOC RP11-296I10.6 RP11-588K22.2 SH2B3 SIK2 SLC4A7 TH1L TMEM133 TNFRSF25 TSPY26P ULK3 YEATS4 ZBTB46 ZNF652 ZNF831
Gout (self-reported) 1.58 2 0 0.0 0.00 1.0e+00 SH2B3 SIPA1
Hypothyroidism/myxoedema (self-reported) 1.65 3 1 2.2 0.00 1.0e+00 MSRA RP5-1115A15.1 SH2B3
Medication: Amlodipine 6.19 19 9 20.0 0.95 1.8e-12 CAPZA1 CLCN6 FAM108C1 FES KCNK3 KDM2B LSP1 MTHFR NPPA-AS1 OSGIN2 RHOC RNF34 RP11-617D20.1 RP4-635E18.7 SLC35F6 TMEM133 TNFSF12 TNNT3 ZNF318
Medication: Ventolin 100micrograms inhaler 1.30 1 0 0.0 0.00 1.0e+00 ZNF652
Birth weight 2.73 13 9 20.0 -0.58 2.9e-02 ADRB1 DBN1 DCAF16 FES FURIN NTN5 SH2B3 SIK2 SLC2A4 SRR TNNT3 UCKL1AS ZNRF3
High blood pressure (siblings) 4.96 9 4 8.9 0.98 2.1e-08 ACP2 CLCN6 FES KAT8 NPPA NRBF2 RHOC SH2B3 TMEM133
Forced vital capacity (FVC), Best measure 1.57 11 5 11.1 -0.44 1.7e-01 ACP2 CENPW DBN1 DCAF16 GMEB2 KAT8 NCOA1 RBL2 RHOC RP11-538P18.2 WNT3
Body fat percentage 2.11 30 11 24.4 0.61 3.9e-04 ABO AC091133.1 CAST CHP1 COX5A CTB-31O20.6 CTSW DCAF16 FAM108C1 FAM57B FLJ12825 HOXA10 HSD17B12 KAT8 KCNK3 KDM2B MRAS MYO9B NOC3L PMS2P5 RNF34 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TEX15 TNFRSF25
Leg fat percentage (right) 2.21 23 12 26.7 0.82 1.4e-06 CHP1 COX5A CTB-31O20.6 CTSW DCAF16 FAM108C1 FAM57B GTF2B HSD17B12 KAT8 KCNK3 KDM2B MOBP MSRA NOC3L RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 STAG3L1 STK32C TEX15 TNFRSF25
Arm fat-free mass (right) 1.88 23 13 28.9 0.17 4.3e-01 ABO C10orf118 CENPW CTSW DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MYO9B NEIL2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 STAG3L1 WDR66
Comparative body size at age 10 1.65 11 6 13.3 0.34 3.1e-01 ATG7 CERS5 EFR3B FAM57B FCF1P2 KAT8 MSRA NTN5 SIPA1 SRR ZNF652
Worry too long after embarrassment 1.10 1 0 0.0 0.00 1.0e+00 MSRA
Seen a psychiatrist for nerves, anxiety, tension or depression 1.37 1 0 0.0 0.00 1.0e+00 ADRB1
Wheeze or whistling in the chest in last year 1.67 3 0 0.0 0.00 1.0e+00 GMEB2 SIK2 ZNF652
Qualifications: College or University degree 1.12 8 2 4.4 -0.75 3.1e-02 DCAF16 FAM57B GTF2B RBL2 STAG3L1 TEX15 TNFRSF25 WNT3
Medication for pain relief, constipation, heartburn 1.95 6 2 4.4 -0.98 5.4e-04 ACE C20orf160 FAM108C1 STK32C UFL1 YEATS4
Neck or shoulder pain in last month 1.42 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Medication: Blood pressure 10.31 68 28 62.2 0.99 1.3e-63 AC091133.1 ACE ACP2 ADRB1 ATP2B1 BICC1 C1GALT1 C20orf160 C4orf22 CAPZA1 CEP41 CHMP1A CISD2 CLCN6 CMIP CSK CTSW CWF19L2 CYB5D1 DCAF16 EFR3B FAM108C1 FAM57B FCF1P2 FES FURIN HOXA10 JARID2 KDM2B KLF16 LDB3 LFNG LSP1 MOBP MSRA MTHFR NELFCD NOC3L NPPA NPPA-AS1 OSGIN2 PDXK PLCB1 PRDM8 PVRIG RGS19 RHOC RNF34 RP11-810M2.2 RP4-635E18.7 SH2B3 SIK2 SIPA1 SLC2A4 SLC4A7 SOX6 STAG3L1 TH1L TMEM133 TNNT3 TSPY26P ULK3 WDR66 ZBTB46 ZC3HC1 ZNF318 ZNF652 ZNF831
Angina (self-reported) 2.91 5 1 2.2 0.97 3.9e-04 FES FURIN OPRL1 RGS19 ZNF652
Migraine (self-reported) 1.28 1 1 2.2 0.00 1.0e+00 UFL1
Medication: Allopurinol 1.58 3 0 0.0 0.00 1.0e+00 CYB5D1 SH2B3 WDR66
Medication: Seretide 50 evohaler 1.36 2 0 0.0 0.00 1.0e+00 PDLIM4 ZNF652
Mean time to correctly identify matches 1.15 2 1 2.2 0.00 1.0e+00 RP11-810M2.2 SH2B3
Whole body fat mass 2.04 28 14 31.1 0.65 2.0e-04 AC091133.1 CAST COX5A CTB-31O20.6 CTSW FAM108C1 FAM57B HOXA10 HSD17B12 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MRAS MSRA NT5C2 PMS2P5 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25
Leg fat mass (right) 2.14 25 12 26.7 0.85 1.0e-07 AC091133.1 CAST CTB-31O20.6 CTSW FAM108C1 FAM57B HSD17B12 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MOBP MRAS MSRA PMS2P5 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 STAG3L1 STK32C TEX15 TNFRSF25 TSPY26P
Arm predicted mass (right) 1.87 24 12 26.7 0.20 3.4e-01 ABO C10orf118 CENPW CMIP DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MYO9B NEIL2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 STAG3L1 TSPY26P WDR66
Pulse rate, automated reading 1.32 6 2 4.4 -0.07 8.9e-01 ABO ACP2 CCDC36 PVRIG RBL2 SIK2
Alcohol intake frequency. 1.60 7 3 6.7 0.69 8.7e-02 ARID3B FAM57B KAT8 NTN5 PMS2P5 TEX15 ZNF318
Comparative height size at age 10 1.57 19 10 22.2 -0.21 3.8e-01 CENPW DBN1 DCAF16 FAM108C1 FAM57B FES GTF2B NCOA1 NTN5 NUCB2 PDLIM4 PIGV RBL2 RP11-617D20.1 RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 SH2B3 WDR66
Number of full sisters 1.37 1 0 0.0 0.00 1.0e+00 NRBF2
Suffer from 'nerves' 1.14 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Overall health rating 2.15 11 5 11.1 0.99 1.3e-09 AC091133.1 CTSW DCAF16 HEXIM1 KAT8 MSRA PMS2P5 RBL2 TEX15 TSPY26P ZNF652
Had major operations 1.22 1 0 0.0 0.00 1.0e+00 ZNF652
Medication: Aspirin 3.97 6 1 2.2 0.95 1.1e-04 AC091133.1 FES GOPC OPRL1 RGS19 SIK2
Knee pain experienced in last month 1.51 1 0 0.0 0.00 1.0e+00 ARID3B
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 1.27 1 0 0.0 0.00 1.0e+00 KDM2B
Illnesses of father: Heart disease 2.55 3 1 2.2 0.74 2.6e-01 ABO FES RGS19
Smoking status: Previous 1.10 1 0 0.0 0.00 1.0e+00 SH2B3
Forced expiratory volume in 1-second (FEV1), predicted 1.31 4 2 4.4 -0.95 4.5e-02 DCAF16 HEXIM1 MGRN1 PDLIM4
Whole body fat-free mass 1.90 23 17 37.8 0.08 7.3e-01 C10orf118 CENPW DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MYO9B NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 SLC4A7 STAG3L1 WDR66
Leg fat-free mass (right) 1.95 28 16 35.6 0.07 7.1e-01 ABCF3 C10orf118 CENPW CTSW DBN1 DCAF16 FAM108C1 FAM57B FES FURIN HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA MYO9B NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 SRR STAG3L1 TDRD1 WDR66
Arm fat percentage (left) 2.19 27 18 40.0 0.70 4.5e-05 ABO AC091133.1 CHP1 COX5A CTB-31O20.6 CTSW DCAF16 FAM108C1 FAM57B FBF1 HOXA10 HSD17B12 KAT8 KCNK3 KDM2B KLF16 MSRA PMS2P5 RNF34 RP11-296I10.6 RP5-1115A15.1 SLC2A4 SRR STAG3L1 STK32C TEX15 TNFRSF25
Average weekly red wine intake 1.27 1 0 0.0 0.00 1.0e+00 MPI
Mood swings 1.24 3 0 0.0 0.00 1.0e+00 ACP2 OSGIN2 WNT3
Loneliness, isolation 1.36 1 0 0.0 0.00 1.0e+00 RP5-1115A15.1
Long-standing illness, disability or infirmity 1.88 3 0 0.0 0.00 1.0e+00 CHP1 PMS2P5 ZNF652
Ever had bowel cancer screening 1.16 1 0 0.0 0.00 1.0e+00 SIK2
Diabetes diagnosed by doctor 2.19 5 2 4.4 1.00 1.6e-04 CTSW MRAS PMS2P5 RBL2 ZBTB46
Mouth/teeth dental problems: Mouth ulcers 1.41 1 0 0.0 0.00 1.0e+00 OSGIN2
Medication for cholesterol 6.77 26 8 17.8 -0.97 1.4e-16 ATG7 C4orf22 CAPZA1 CENPW CHMP1A CISD2 CMIP FES HOXA10 JARID2 KAT8 LSP1 MGRN1 NTN5 PIGV PLCB1 PRKD3 RBL2 RGS19 RHOC SH2B3 TMEM133 VEGFB ZBTB46 ZNF831 ZNRF3
Back pain experienced in last month 1.60 1 0 0.0 0.00 1.0e+00 WDR66
Mineral and other dietary supplements 1.30 1 0 0.0 0.00 1.0e+00 NRBF2
Breast cancer (self-reported) 1.42 1 0 0.0 0.00 1.0e+00 SLC4A7
Asthma (self-reported) 1.84 6 4 8.9 0.43 4.0e-01 FBF1 HDAC7 PDLIM4 RP5-1115A15.1 SIK2 ZNF652
Osteoarthritis (self-reported) 1.64 2 0 0.0 0.00 1.0e+00 COX5A RPP25
Medication: Aspirin 4.14 5 1 2.2 0.93 6.7e-04 FES OPRL1 RGS19 SIK2 VEGFB
Illnesses of father: None of the above (group 1) 2.62 2 1 2.2 0.00 1.0e+00 FES SH2B3
Forced expiratory volume in 1-second (FEV1), predicted percentage 1.68 5 3 6.7 -0.22 7.2e-01 KAT8 NRBF2 RP11-538P18.2 TMEM170A WNT3
Whole body water mass 1.91 23 17 37.8 0.07 7.4e-01 C10orf118 CENPW DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA MYO9B NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 STAG3L1 WDR66
Leg predicted mass (right) 1.94 27 16 35.6 0.05 8.1e-01 ABCF3 C10orf118 CENPW DBN1 DCAF16 FAM108C1 FAM57B FES FURIN HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA MYO9B NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 SRR STAG3L1 TDRD1 WDR66
Arm fat mass (left) 2.15 29 12 26.7 0.61 4.5e-04 AC091133.1 CAST COX5A CTB-31O20.6 CTSW EFR3B FAM108C1 FAM57B FBF1 HOXA10 HSD17B12 KAT8 KCNK3 KDM2B KLF16 MRAS MSRA NT5C2 PMS2P5 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 SRR STAG3L1 STK32C TDRD1 TEX15 TNFRSF25
Number of self-reported non-cancer illnesses 4.96 16 6 13.3 0.97 1.4e-12 CISD2 CLCN6 CYB5D1 GMEB2 HDAC7 MYO9B NTN5 OPRL1 PDLIM4 PMS2P5 RGS19 SH2B3 ZNF318 ZNF652 ZNF831 ZNRF3
Miserableness 1.15 3 0 0.0 0.00 1.0e+00 ACP2 RP5-1115A15.1 WNT3
Eye problems/disorders: Glaucoma 1.22 1 0 0.0 0.00 1.0e+00 TEX15
Medication: Blood pressure 11.08 89 39 86.7 0.99 9.7e-76 ACE ACP2 ADRB1 AGT AKR1B1 ARID3B ATG7 ATP2B1 C1GALT1 C4orf22 CACNB2 CAPZA1 CENPW CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTSW CWF19L2 CYB5D1 FAM108C1 FCF1P2 FES FLJ12825 FURIN GMEB2 GTF2B HEXIM1 HOXA10 HRCT1 KAT8 KB-1107E3.1 KCNK3 KDM2B LFNG LSP1 MGRN1 MPI MRAS MSRA MTHFR MYO9B NCOA1 NEIL2 NPPA NRBF2 NSUN6 NT5C2 NTN5 OPRL1 PDLIM4 PDXK PIGV PLCB1 PRKD3 PTPN12 RGS19 RHOC RNF34 RP11-1055B8.4 RP11-588K22.2 RP11-810M2.2 RP4-635E18.7 RPP25 SH2B3 SIK2 SIPA1 SLC2A4 SLC35F6 SLC4A7 TBC1D19 TDRD1 TEX15 TMEM133 TNFSF12 TNNT3 UBL7 UCKL1AS ULK3 VEGFB WNT3 ZBTB46 ZNF318 ZNF831 ZNRF3
Supplements: Fish oil (including cod liver oil) 1.07 1 0 0.0 0.00 1.0e+00 HEXIM1
High cholesterol (Self-reported) 3.74 10 7 15.6 0.61 2.0e-02 ABO CLCN6 DCAF16 FBF1 NTN5 OPRL1 PIGV RGS19 TMEM133 VEGFB
Medication: Bendroflumethiazide 7.33 33 11 24.4 0.97 5.1e-22 ABCF3 ACP2 ADRB1 AGT ATP2B1 CACNB2 CAPZA1 CHMP1A CLCN6 CSK FAM108C1 FAM57B FES HOXA10 KAT8 LSP1 MGRN1 MYO9B NEIL2 NRBF2 NTN5 PDLIM4 PIGV PLCB1 RHOC SH2B3 SLC35F6 SLC4A7 TEX15 TMEM133 TNFSF12 USP37 ZNF831
Medication: Paracetamol 1.72 1 0 0.0 0.00 1.0e+00 UFL1
Medication: Lisinopril 4.55 6 0 0.0 0.98 5.5e-04 ACP2 CSK FCF1P2 LSP1 NRBF2 ZNF831
Medication: Atorvastatin 2.09 1 0 0.0 0.00 1.0e+00 ABO
Illnesses of father: High blood pressure 4.31 6 1 2.2 0.99 1.0e-05 ACE C4orf22 CHMP1A FES NCOA1 PLCB1
Ever smoked 1.28 2 0 0.0 0.00 1.0e+00 SH2B3 SRR
Basal metabolic rate 1.91 23 17 37.8 0.18 4.0e-01 C10orf118 CENPW CTSW DBN1 DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 STAG3L1 WDR66
Leg fat percentage (left) 2.23 23 10 22.2 0.82 1.7e-06 CHP1 COX5A CTB-31O20.6 CTSW DCAF16 FAM108C1 FAM57B GTF2B HSD17B12 KAT8 KCNK3 KDM2B MOBP MSRA PMS2P5 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 STAG3L1 STK32C TEX15 TNFRSF25
Arm fat-free mass (left) 1.87 26 13 28.9 0.31 1.3e-01 ABO C10orf118 CENPW CMIP CTSW DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA NEIL2 NT5C2 PDE1A PDLIM4 RBL2 RP11-810M2.2 SH2B3 SLC35F6 STAG3L1 TSPY26P WDR66
Irritability 1.28 3 3 6.7 0.00 1.0e+00 CCDC36 MSRA NEIL2
Risk taking 1.25 2 0 0.0 0.00 1.0e+00 KCNK3 STK32C
Diastolic blood pressure, automated reading 9.02 84 53 117.8 0.97 9.8e-60 ABO AC006111.1 AC091133.1 ACE ACP2 ADRB1 AGT ATP2B1 C10orf118 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CENPW CEP41 CERS5 CHP1 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTSW CWF19L2 CYB5D1 DCAF16 ENPEP FAM108C1 FCF1P2 FES FURIN GMEB2 HDAC7 HEXIM1 HOXA10 HRCT1 IPO11 KAT8 LFNG LSP1 MPI MSRA MTHFR MYO9B NCOA1 NDUFAF6 NEIL2 NELFCD NOC3L NPPA NPPA-AS1 NRBF2 NSUN6 NT5C2 PDLIM4 PHIP PIGV PMS2P5 PVRIG RGS19 RHOC RP11-296I10.6 RP11-538P18.2 RP5-1115A15.1 RPP25 SH2B3 SIPA1 SLC2A4 SRR STAG3L1 SWAP70 TBC1D19 TCEA2 TCHP TH1L TMEM133 TNFSF12 TUBB1 UBL7 ULK3 ZC3HC1 ZNF652 ZNF831
Myopia 1.21 1 0 0.0 0.00 1.0e+00 CAPZA1
Vascular/heart problems diagnosed by doctor 14.42 153 114 253.3 -1.00 1.6e-176 ABCF3 ABO AC006111.1 AC091133.1 ACE ACP2 ADRB1 ADRB2 AGT AKR1B1 ARID3B ATG7 ATP2B1 BICC1 C10orf118 C1GALT1 C20orf160 C4orf22 CACNB2 CAPZA1 CAST CCDC36 CENPW CEP41 CERS5 CHMP1A CHP1 CISD2 CLCN6 CMIP COX5A CSK CTB-31O20.6 CTSW CWF19L2 CYB5D1 DCAF16 EFR3B ENPEP EXOC4 FAM108C1 FAM57B FBF1 FCF1P2 FCN3 FES FLJ12825 FURIN GMEB2 GOPC GTF2B HDAC7 HEXIM1 HOXA10 HRCT1 HSD17B12 INPP5A IPO11 JARID2 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 LDB3 LFNG LSP1 MGRN1 MOBP MPI MRAS MSRA MTHFR MYO9B NCOA1 NDUFAF6 NEIL2 NELFCD NOC3L NPPA NPPA-AS1 NRBF2 NSUN6 NT5C2 NTN5 NUCB2 OPRL1 OSGIN2 PDE1A PDLIM4 PDXK PHIP PIGV PLCB1 PMS2P5 PRDM8 PRKD3 PTPN12 PVRIG RBL2 RGS19 RHOC RNF34 RP11-1055B8.4 RP11-296I10.6 RP11-538P18.2 RP11-588K22.2 RP11-617D20.1 RP11-810M2.2 RP4-635E18.7 RP5-1115A15.1 RPP25 SGOL1 SH2B3 SIK2 SIPA1 SLC2A4 SLC35F6 SLC4A7 SOX6 SRR STAG3L1 STK32C SWAP70 TBC1D19 TCEA2 TCHP TDRD1 TEX15 TH1L TMEM133 TMEM170A TNFRSF25 TNFSF12 TNNT3 TSPY26P TUBB1 UBL7 UCKL1AS UFL1 ULK3 USP37 VEGFB WDR66 WNT3 YEATS4 ZBTB46 ZC3HC1 ZNF318 ZNF641 ZNF652 ZNF831 ZNRF3
Cholesterol lowering medication 3.38 8 6 13.3 0.73 6.6e-03 ABO DCAF16 NTN5 OPRL1 PIGV RGS19 RNF34 VEGFB
Pain experienced in last month 1.54 2 0 0.0 0.00 1.0e+00 KAT8 UFL1
Heart attack/myocardial infarction (self-reported) 2.52 4 1 2.2 0.97 6.9e-03 FES SH2B3 ZC3HC1 ZNF652
Deep venous thrombosis (DVT) (self-reported) 2.95 1 1 2.2 0.00 1.0e+00 ABO
Heart disease (siblings) 1.87 2 0 0.0 0.00 1.0e+00 FES PVRIG
Pack years of smoking 1.27 1 0 0.0 0.00 1.0e+00 PMS2P5
Impedance of whole body 2.23 39 20 44.4 -0.35 2.7e-02 ABCF3 ABO ATG7 CCDC36 CENPW CEP41 CERS5 CISD2 CTB-31O20.6 CTSW DBN1 FAM108C1 FAM57B FLJ12825 HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 LSP1 MSRA MYO9B NEIL2 NOC3L NT5C2 NUCB2 PDE1A PMS2P5 PRKD3 RGS19 RP11-296I10.6 SLC4A7 SRR STAG3L1 SWAP70 TNFSF12 USP37 ZNF641 ZNF652
Leg fat mass (left) 2.15 26 14 31.1 0.83 1.2e-07 AC091133.1 CAST COX5A CTB-31O20.6 CTSW FAM108C1 FAM57B HSD17B12 KAT8 KB-1107E3.1 KCNK3 KDM2B KLF16 MSRA PDE1A PMS2P5 RP11-296I10.6 RP11-810M2.2 RP5-1115A15.1 RPP25 STAG3L1 STK32C TDRD1 TEX15 TNFRSF25 TSPY26P
Arm predicted mass (left) 1.90 25 13 28.9 0.30 1.5e-01 ABO C10orf118 CENPW CMIP CTSW DCAF16 EFR3B FAM108C1 FAM57B HEXIM1 HSD17B12 KAT8 KCNK3 KLF16 MSRA NCOA1 NEIL2 NT5C2 PDE1A PDLIM4 RBL2 SH2B3 SLC35F6 STAG3L1 WDR66

Associations by panel

study tissue # hits % hits/tests avg chisq
GTEx Adipose Subcutaneous 37 1.06 2.9
GTEx Adipose Visceral Omentum 16 0.79 3.0
GTEx Adrenal Gland 15 1.03 2.9
GTEx Artery Aorta 40 1.34 3.1
GTEx Artery Coronary 10 0.85 2.9
GTEx Artery Tibial 44 1.17 3.0
GTEx Brain Caudate basal ganglia 5 0.54 2.9
GTEx Brain Cerebellar Hemisphere 15 1.01 2.9
GTEx Brain Cerebellum 19 0.96 3.0
GTEx Brain Cortex 8 0.77 3.1
GTEx Brain Frontal Cortex BA9 9 0.97 3.0
GTEx Brain Hippocampus 2 0.38 2.8
GTEx Brain Hypothalamus 1 0.17 2.7
GTEx Brain Nucleus accumbens basal ganglia 5 0.58 2.9
GTEx Brain Putamen basal ganglia 4 0.64 2.7
GTEx Breast Mammary Tissue 20 1.01 2.9
GTEx Breast Mammary Tissue (Male) 14 1.17 2.9
GTEx Breast Mammary Tissue (Female) 17 1.03 2.9
GTEx Cells EBV-transformed lymphocytes 8 0.56 2.8
GTEx Cells Transformed fibroblasts 35 0.83 2.8
GTEx Colon Sigmoid 17 1.16 2.9
GTEx Colon Transverse 18 0.87 2.9
GTEx Esophagus Gastroesophageal Junction 15 1.04 3.0
GTEx Esophagus Mucosa 32 0.96 2.9
GTEx Esophagus Muscularis 36 1.11 2.9
GTEx Heart Atrial Appendage 14 0.89 2.8
GTEx Heart Left Ventricle 18 1.18 2.9
GTEx Liver 6 0.84 2.6
GTEx Lung 26 0.90 3.0
GTEx Muscle Skeletal 23 0.80 2.9
GTEx Nerve Tibial 34 0.79 2.8
GTEx Ovary 11 1.21 3.3
GTEx Pancreas 15 0.92 2.9
GTEx Pituitary 11 0.99 2.9
GTEx Prostate 14 1.68 3.2
GTEx Skin Not Sun Exposed Suprapubic 28 1.14 3.0
GTEx Skin Sun Exposed Lower leg 39 1.07 2.9
GTEx Small Intestine Terminal Ileum 3 0.65 3.0
GTEx Spleen 11 0.78 2.8
GTEx Stomach 19 1.31 3.1
GTEx Testis 31 0.98 2.9
GTEx Thyroid 41 1.03 2.9
GTEx Uterus 6 1.06 2.8
GTEx Vagina 5 0.79 3.0
GTEx Whole Blood 15 0.75 2.8
METSIM Adipose 25 0.54 2.5
NTR Blood 17 0.71 2.7
ROSMAP Brain Pre-frontal Cortex 54 1.23 3.0
YFS Blood 28 0.61 2.6
CommonMind Brain Pre-frontal Cortex 45 0.84 2.7
The Cancer Genome Atlas Bladder Urothelial Carcinoma 10 0.60 2.6
The Cancer Genome Atlas Breast Invasive Carcinoma 34 0.77 2.7
The Cancer Genome Atlas Cervical Squamous Cell Carcinoma 7 0.64 2.6
The Cancer Genome Atlas Colon Adenocarcinoma 23 1.11 2.8
The Cancer Genome Atlas Esophageal Carcinoma 3 0.44 2.6
The Cancer Genome Atlas Glioblastoma Multiforme 6 0.59 2.6
The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma 18 0.66 2.6
The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma 35 0.85 2.8
The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma 17 0.83 2.7
The Cancer Genome Atlas Brain Lower Grade Glioma 27 0.63 2.6
The Cancer Genome Atlas Liver Hepatocellular Carcinoma 6 0.54 2.5
The Cancer Genome Atlas Lung Adenocarcinoma 25 0.85 2.6
The Cancer Genome Atlas Lung Squamous Cell Carcinoma 19 0.76 2.6
The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma 13 0.82 2.7
The Cancer Genome Atlas Pancreatic Adenocarcinoma 18 1.08 2.8
The Cancer Genome Atlas Pheochromocytoma and Paraganglioma 12 0.90 2.7
The Cancer Genome Atlas Prostate Adenocarcinoma 28 0.61 2.5
The Cancer Genome Atlas Rectum Adenocarcinoma 6 0.87 2.7
The Cancer Genome Atlas Soft Tissue Sarcoma 5 0.47 2.6
The Cancer Genome Atlas Skin Cutaneous Melanoma 2 0.37 2.7
The Cancer Genome Atlas Stomach Adenocarcinoma 15 0.89 2.8
The Cancer Genome Atlas Testicular Germ Cell Tumors 6 0.47 2.6
The Cancer Genome Atlas Thyroid Carcinoma 39 0.76 2.6
The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma 4 0.79 2.6