Best TWAS P=1.24e-09 · Best GWAS P=1.28e-09 conditioned to 0.000945
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | ADAM19 | 0.14 | 0.03 | enet | 19 | 0.09 | 2.4e-06 | -4.0 | 6.1 | 1.2e-09 | 0.54 | 0.12 | 0.79 | TRUE |
| 2 | GTEx | Muscle Skeletal | ADAM19 | 0.06 | 0.02 | lasso | 4 | 0.01 | 1.5e-02 | 4.1 | 5.5 | 3.7e-08 | 0.58 | 0.14 | 0.76 | FALSE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | ADAM19 | 0.10 | 0.01 | lasso | 4 | 0.08 | 5.2e-05 | 4.9 | 6.0 | 1.5e-09 | 0.74 | 0.06 | 0.92 | FALSE |
| 4 | GTEx | Whole Blood | ADAM19 | 0.12 | 0.07 | enet | 20 | 0.07 | 9.8e-07 | 5.4 | 6.0 | 2.6e-09 | 0.62 | 0.10 | 0.90 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | ADAM19 | 0.08 | 0.02 | blup | 159 | 0.03 | 5.3e-04 | 3.2 | 5.5 | 4.9e-08 | 0.37 | 0.15 | 0.14 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | ADAM19 | 0.09 | 0.03 | lasso | 4 | 0.05 | 2.4e-06 | 4.1 | 5.8 | 5.7e-09 | 0.61 | 0.21 | 0.76 | FALSE |
| 7 | The Cancer Genome Atlas | Thyroid Carcinoma | ADAM19 | 0.07 | 0.00 | blup | 159 | 0.02 | 2.0e-03 | -4.0 | 5.5 | 2.8e-08 | 0.39 | 0.16 | 0.08 | FALSE |